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Hi, everyone a short update on me: after having developed a rash on my scrotum 2 months ago, and embarking on a diet aimed at eliminating candida from my system, I have experienced some good results. I have been able to think more rationally and compose more logical statements than I usually do. I can't say that the feeling of brain fog goes away, so my attention is still rather bad. But I noticed a marked improvement in my ability to express myself and find the words I need. I typically have a log-jam of vocabulary all wanting to be used. But during the various holiday parties I attended with no shortage of well-spoken people with masters and doctorate degrees, I found it especially easy to say what I wanted! Felt nostalgic for times when I have been that high functioning My rash still remains though. I see a dermatologist next month. I have a strong suspicion it is what is called an intertrigo, of the candidal variety. The rash itself isn't too terrible to deal with, but I need to deal with it sooner than later.The diet I've been on has also included taking supplements to eliminate the candida, namely natural anti-fungals and probiotics. For the first month I was quite sick, dealing with the Herx reaction or "die off" where you feel worse before better. I backed off the treatments during the holidays so that I could survive the germ sharing that would go on with my relatives around. I'm back to taking them, and I see myself staying on this program for another month at least. I think I will be taking probiotics for some time afterwards to make sure I keep my gut healthly.In short, this experiment has made it easier to cope with my POIS symptoms, as I feel like a healthier, happier person overall.I am pretty experienced at this program by now, so if anyone wants to know more about it I'd be happy to answer questions.
Hi, My name is sohail. i'm a 21 years old male and i'm from Iran. Now it's about a year that i've understood i have POIS.That was totally by chance after searching google "depression after sex" and reading an article about POIS in mighty wikipedia. I'm so happy i found that i'm sick. I believe this sickness badly affected all dimentions of my life.After a little search i understood (i'm totally sure) my pois is an autoimmune reaction toward my own semen. my immune system recognise my semen(after ejaculation) as an enemy and releases histamine and all the disaster starts. Once i ate my own semen and i got sick! Therefore i try to reach orgasm without ejaculation. Sometimes i'm unable to control my orgasms and i ejaculate. I've learned i should take loratadine 2 hours before orgasm(the key factor is before orgasm); But since i'm unable to plan my ejaculations, i take loratadine minutes after orgasm and it steal works with 50% power. antihistamines work greatly in my case(loratadine and diphenhydramine for sleep).loratadine works on h1 receptors. it improves 100% bodily symptoms and 50% of psycological ones for me specially if i take it 2 hours before ejaculation.mechanism of disease:when semen enters the urethra, immune system releases histamine.Histamine exerts its actions by combining with specific cellular histamine receptors. The four histamine receptors that have been discovered in humans and animals are designated H1 through H4, and are all G protein-coupled receptors (GPCR).Type Location FunctionH1 histamine receptor Found on smooth muscle, endothelium, and central nervous system tissue Causes, bronchoconstriction, bronchial smooth muscle contraction, vasodilation, separation of endothelial cells (responsible for hives), and pain and itching due to insect stings; the primary receptors involved in allergic rhinitis symptoms and motion sickness; sleep and appetite suppression.H2 histamine receptor Located on parietal cells and vascular smooth muscle cells Primarily involved in vasodilation. Also stimulate gastric acid secretionH3 histamine receptor Found on central nervous system and to a lesser extent peripheral nervous system tissue Decreased neurotransmitter release: histamine, acetylcholine, norepinephrine, serotoninH4 histamine receptor Found primarily in the basophils and in the bone marrow. It is also found on thymus, small intestine, spleen, and colon. Plays a role in chemotaxis....sorry, you cannot view external links. To see them, please
REGISTER or LOGIN. I think it's best not to post about new theories over there (as it's against the rules) but you could read the posts if you want. The h3 idea isn't new. H3 blockers aren't widely available. Alternatives are mast cell stabilisers. Just so you know, everyone releases histamine when there's an erection. When h2 blockers are given to someone, it impedes them getting an erection. That doesn't mean there's not an immunological reaction going on here but the question is why are POIS sufferers different rather than why do POIS sufferers have histamine release upon an O.
4) Lastly, speaking of abstaining, it is something that I finally managed to do for over 2 weeks now. My results so far have been mixed. I think I feel about 40-50% better. But I still have some brain fog and mild headache. This could be simply because I haven't abstained long enough and also because I have still been masturbating/having sex with my gf, but NO orgasm (I know it's really difficult though). I plan to keep abstaining indefinitely and see what happens (to see if I have constant pois, to see if I can feel normal again, and just to feel better overall).K, thanks guys and I hope to post again soon! I'll be bock (arnold voice, ha).And before I forget, thanks Herman for all that info you've been sharing with us! It's very interesting to read.
Vincent M, it is quite strange that you talk about survival, yet you need to procreate once a day ))If you have masturbation addiction, then this is your problem, if not I dont see a problem staying away from sex. If niacin helps you then most likely you are over methylated
Do you feel the headache come on when you masturbate, even without orgasm i.e. release of seminal fluid. I do... Not all POIS sufferers seem to have that problem or maybe they don't notice it. It's interesting...
Also my erections are fine. I do agree that if I had more energy my willpower to abstain would increase a bit, but it's silly to say that sex drive is not a factor in masturbation frequency.
Often I get a headache from just masturbating with no orgasm. Mainly though the effects I feel are cognitive problems such as unexplained mental exhaustion and a weird lightheaded feeling and also tightness feeling in my scalp. This is pretty much the same feeling I get after an orgasm, except it is a lot worse. I remember someone describing here one time a feeling like hot wax over their head. This is what I feel too, and it's one of my worst and most disliked pois symptoms; it also corresponds with a lot of brain fog/mental fatigue. POIS can be really weird.Prancer
how can one masturbate without O plz explain,i dont understand this..on a side not you people dont reply to me.i dont know if u dont see my post or just ignore
Vincent M. When were these done? Also please post your thyroid tests here. There is no such thing as normal tests. The ranges used in the labs are worthless/ The important thing is how one gland works against another. Looking at your tests, your problem is quite clear. You might be in POIS type 1. ( I still need the thyroid to prove that) . Му e-mail is firstname.lastname@example.orgCan you please send me stuff there. And I will respond to you with more explanation on what is going on.
low serotonin levels can result in a significantly higher sex drive to the point of potential sexual addiction.
low dopamine can cause addictive behavior.
Also, Kurtosis would not let me forget that histamine levels play a large role too. If you believe you need to wear a chastity belt, I'd bet your histamine levels are super high and you're very easily stimulated.
VIncent M, what are you trying to do with methionine. TO detoxify your liver you need choline, inositol and methionine. 500 mg 3 times a day but it wont have any effect on POIS even if you do this for a year. You cant take stuff before orgasm and hope for it to cure your POIS, since it takes 3 months to break the cycle with no sex.
Romuloid Raimus, I'm curious to know if you tested any of these supplements separately or if you just began them all at the same time.I've had a lot of luck with herbs, but no luck with vitamins. Can you attribute any improvement specifically to the vitamins that you're taking or do you think most of your symptom reduction has been from the herbs?
Good question... Yes, I've tested them all separately. I feel a small improvement in symptoms from taking the multi-vitamin alone... I take it mainly for general health and well being, and like I said, to ensure I have no deficiencies. The iron is precautionary as well. ZMA, on the other hand, has a profound impact on me, and many who take it. The ingredients are simple, but it is very powerful, maybe the most powerful in my stack. I recommend that if you try it, you start with a low dose, and increase slowly. I notice smaller-but-noticable improvements with the omega 3's and the aminos as well. I take considerably low doses of everything in my stack, my logic being that its probably better to spread out your intake of these substances, rather than to take massive amounts of one or two. Just seems more balanced to me. Hope this helps.-RR
Vincent M, I posted on the russian POIS site on the same day I posted here, which is couple of days before New Years, since it was my New Years resolution. Your problem is that you dont understand that over and undermethylation does not mean anything for POIS sufferer at all...what matters is dopamine/ serotonin ratio. That is why you are taking stuff for low serotonin and low dopamine , taking SAMe and all other delitant stuff where you have to be fixing the actual ratio of dopamine/serotonin. If you have low serotonin and high dopamine and you take SAMe, you will get screwed. LMAO Most severe POIS suffers are mixed, with screwed up dopamine./ serotonin level... You cant know that ratio from blood tests ,since the levels are changing really fast.... this is systemic knowledge, that is why you should give me tests and stop being a delitant in denial, LMAO
Quote from: Romuloid Raimus on 06/01/2013 21:59:39Good question... Yes, I've tested them all separately. I feel a small improvement in symptoms from taking the multi-vitamin alone... I take it mainly for general health and well being, and like I said, to ensure I have no deficiencies. The iron is precautionary as well. ZMA, on the other hand, has a profound impact on me, and many who take it. The ingredients are simple, but it is very powerful, maybe the most powerful in my stack. I recommend that if you try it, you start with a low dose, and increase slowly. I notice smaller-but-noticable improvements with the omega 3's and the aminos as well. I take considerably low doses of everything in my stack, my logic being that its probably better to spread out your intake of these substances, rather than to take massive amounts of one or two. Just seems more balanced to me. Hope this helps.-RRThanks for your detailed response. I have tried magnesium and zinc with no effect, but they weren't good quality and I only took them for about a week. How long did you have to take the vitamins for before you noticed an improvement?
Quote from: Vincent M on 07/01/2013 00:58:24Thanks for your detailed response. I have tried magnesium and zinc with no effect, but they weren't good quality and I only took them for about a week. How long did you have to take the vitamins for before you noticed an improvement?Several hours. Perhaps I should note that I only take high quality supplements, i.e. I buy from the big brands only.
Thanks for your detailed response. I have tried magnesium and zinc with no effect, but they weren't good quality and I only took them for about a week. How long did you have to take the vitamins for before you noticed an improvement?
one thing I gaurantee you is that I know how to cure this thing .