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Quote from: gondal4 on 08/10/2013 15:50:15Quote from: Kima on 07/10/2013 16:28:35It is strange to me Selenium-methionine helps relieve the symptoms of poisKima what an idiot u r,u said u were cured by germany?Treatment Herman, does not helpHerman knows no cure poisHe conducted experiments on usKima,Russia
Quote from: Kima on 07/10/2013 16:28:35It is strange to me Selenium-methionine helps relieve the symptoms of poisKima what an idiot u r,u said u were cured by germany?
It is strange to me Selenium-methionine helps relieve the symptoms of pois
Gonda. I said Germany not Herman, you idiot. I have no idea if Hermans cure works , he never treated me. I am getting my hairtest tommorow from ARL, but some people on the russian forum are feeling much better in 2 days on his diet already.Too bad he wont help you , morons any more. HAHA
"Collectively these observations support the idea that autoimmune disease may in part be considered as localised pellagra manifesting symptoms particular to the inflamed target tissues."
"Distinct among the NAD precursors, nicotinic acid specifically activates the g-protein coupled receptor (GPCR) GPR109a to produce the IDO-inducing tolerogenic prostaglandins PGE(2) and PGD(2). Next, PGD(2) is converted to the anti-inflammatory prostaglandin, 15d-PGJ(2)"
"The importance of IDO dysregulation manifest as autoimmune pellagric dementia is genetically illustrated for Nasu-Hakola Disease (or PLOSL), which is caused by a mutation in the IDO antagonizing genes TYROBP/DAP12 or TREM2. Loss of function leads to psychotic symptoms rapidly progressing to presenile dementia likely due to unchecked increases in microglial IDO expression, which depletes neurons of tryptophan causing neurodegeneration"
Alternatively the direct targeting of the non-redox NAD-dependent proteins using resveratrol to activate SIRT1 or PJ34 in order to inhibit PARP1 and prevent autoimmune pathogenesis are also given consideration.
[CITATION] W1236 NOD2 Mutations Compromise Host Defense Mechanisms to Enteric Bacteria as Shown by Decreased NF-kB in Human B Cells After Muramyl …Z Lin, G John, JP Hegarty, A Berg, TY Li, DM Pastor… - …, 2010 - WB SaundersAll 2 versions Cite[CITATION] W1234 Non-Synonymous Polymorphisms in the Tryptophan Catabolism Pathway: Correlation to Crohn's Disease Risk and PhenotypeA Lee, N Gupta, WF Stenson, MA Ciorba - Gastroenterology, 2010 - WB SaundersAll 2 versions Cite[CITATION] W1233 Genotype-Subphenotype Correlations Between Established Crohn's Disease Risk Alleles and Disease LocationA Lee, TZ Li, H Chen, T Zhang, W Zhu, E Li - Gastroenterology, 2010 - WB SaundersAll 2 versions Cite[CITATION] W1235 Inflammatory Bowel Disease (IBD)-Associated DNA Methylation in B Cells From IBD PatientsZ Lin, JP Hegarty, W Yu, JA Cappel, X Chen… - …, 2010 - WB SaundersAll 2 versions Cite[CITATION] W1237 Haptoglobin Poymorphisms are Associated With Ulcerative Colitis and Crohn's DiseaseL Marquez, I Cleynen, K Machiels, S Organe… - …, 2010 - WB SaundersAll 2 versions CiteThe human indoleamine 2, 3-dioxygenase gene and related human genesMF Murray - Current drug metabolism, 2007 - ingentaconnect.com... 1 rs35059413 G124A (unknown) first A 4 T Exon 1, nonsynonymous 2 rs35099072 G344A(unknown) second R 77 H Exon 3, nonsynonymous 3 rs12545877 G428A (G) second R 105K Exon 4, nonsynonymous 4 rs4463407 T434G (T) second I 107 S Exon 4, nonsynonymous ...Cited by 23 Related articles All 4 versions Cite[CITATION] W1232 A Highly Significant Association of Tumor Necrosis Factor Superfamily Member 15 Gene With Inflammatory Bowel Disease in ChinaF Zhou, T Jiang, L Ge, Z Chen, J Zhao, B Xia - Gastroenterology, 2010 - WB SaundersAll 2 versions Cite
i also had a amino acids test done by great plains laboratory, and all of them were low or very low.
Hi,We finally reached the success with Gaurav's POIS and now he completely cures from POIS. But cause for his POIS is completely different from mine where for me it is due to accumulation of toxins in the body and the same was cleared through panchakarma process. Whereas as updated earlier, we (my dr.kumar's suggestion) tried panchakarma treatment on Gaurav, but found 40% result and his POIS bounce back after two months. Again in coordination with Gaurav's physician, Dr.Kumar suspected nervous system imbalance is the reason for the Gaurav's POIS. For this he suggested various medicines and nothing worked on him. Finally, Gaurav found Wisdom Tooth in both sides of his lower jaw and apparently there was no physical pain. In X-ray it is found that the Wisdom tooth gone depth and due to this there was a imbalance in nervous system function of Gaurav. One month back, he removed his Wisdom Tooth by extraction (small dental surgery) and now he is out of POIS. This is the result of Gaurav's status.
QuoteFenugreek is still doing a good job for me, I'm pleased to say.That's a good point Hurray. For the moment, we must be content with such small successes.
Fenugreek is still doing a good job for me, I'm pleased to say.
I haven't contributed for a while as I have been completely O-free for a long time. But last night I had an NE but I am happy to report that I have no POIS effects.
That's good news John ! There is no difference between NE and normal orgasm for me too. You must continue your experience to see if it works several times. From my experience, you need a lot of food to hope a real but small effect. I will have a look on these beans (I think I eat same familly of these beans but maybe a different version).Edit :Yes, some studies showed a improvement of Parkinson's disease with these beans.http://www.ncbi.nlm.nih.gov/pubmed/1527547?dopt=Citation [Links inactive - To make links active and clickable, login or click here to register]http://www.ncbi.nlm.nih.gov/pubmed/10634260?dopt=Citation [Links inactive - To make links active and clickable, login or click here to register]It's a really good idea ! 250g of beans 5-10 hours before orgasm.It seems all these bean are the same family or close, probably all contains L-Dopa : "broad beans", "fèves" (in french). I would say I usually eat them 2 or 3 times a year.I wonder if your finding could be a real test for Pois sufferers to know once and for all if dopamine is part of Pois or not.
Had strong POIS from urinating ,it had some sperm in it.
After sex i truly have no immune defense what so ever.What has the forum come up with so far about the possibility of this being a sexually transmittable infection?
Quote from: johanstefansson on 21/11/2013 16:12:44After sex i truly have no immune defense what so ever.What has the forum come up with so far about the possibility of this being a sexually transmittable infection?How did they diagnose you with Lyme dicease?Not quite as dramatic as you say J otherwise you would be getting sick to a lot more things then just a cold, and you would be succumbing to them just like AIDS patients. For me when I was younger I did notice how I would often seem to get a cold the day after having an O, but it would not be continuous throughout the year. Generally only through the flu seasons. It would be a case of many people in the office having the flu and I would be fine for the week, but then when I have an O, bam I'd get the flu the next day. This was during my teens + 20s, but not anymore. I do have an irregular immune system though. What I do have is Lymphopenia with reduced Neutrophils, T Cells and Lymphocytes. The doctors did not do anything about it as I hardly ever get any infections anymore (which is weird in that now I never get a cold) so they seem to think the lower numbers are coping well. I was diagnosed with Lyme disease earlier this year, so that supposedly might explain my irregular lymphocyte subsets.As for STD, I got POIS before I had sex in my teens and I feel that is the same situation for quite a few others here. It is not an STD. I have had STD checks done in past years and came back clear.
Any news on how the POIS research is going with the $30,000 NORD grant? Or any news on when there will be some more news?
hellodemografx When will the [POIS] research [begin with NORD]?thank you
Quote from: hurray on 13/11/2013 13:07:57Any news on how the POIS research is going with the $30,000 NORD grant? Or any news on when there will be some more news?Quote from: Kima on 16/11/2013 17:26:40hellodemografx When will the [POIS] research [begin with NORD]?thank youThis December.
Yes, i have retrognathia and my lower jaw is shorter than the upper. So for both questions: yes. Whats his theory?
EDIT: Other notable bone/joint issues for me are pectus excavatum (bowl chest) and hyper-mobile joints.
Quote from: demografx on 24/11/2013 19:32:19Quote from: hurray on 13/11/2013 13:07:57Any news on how the POIS research is going with the $30,000 NORD grant? Or any news on when there will be some more news?Quote from: Kima on 16/11/2013 17:26:40hellodemografx When will the [POIS] research [begin with NORD]?thank youThis December.I should be getting an update first week in December, maybe not who or what yet, but they are in the final throes of choosing the researcher.So very soon we should know.The first real professionally administered and controlled research on POIS.Whatever the results, it will have to be useful.I'll let you all know when the news comes out.
davemanI and my Russian friends will be waiting impatientlythank you
Herman treatment is no longer valid, a waste of time, I drank a full course of mineralsat the time of improvement were, but then ceased act treatment, this man does not know how to treat (Pois) .I made a mistake in it forgive me Sorry that I defended him
Hi all when I am in pois I have trouble speaking clearly and communicating,I can't find words, I Pronounce some words wrong like (shall-sal.. ) like lettel cheldren causing me shame.
... I have EMS (electro magnetic sensitivity) which I developed at the same time as POIS (late teens). So for me the discovery of anything contributing to beating that disorder would inevitably also help me clear up POIS. I recently discovered this video on youtube. It's called Beating Electrical Sensitivity and includes research done from nobel prize winning psychiatrist David R. Hawkins
The majority of provocation trials to date have found that self-described sufferers of electromagnetic hypersensitivity are unable to distinguish between exposure to real and fake electromagnetic fields, and it is not recognized as a medical condition by the medical or scientific communities.
I am not that guy who comes with a cure twice a year but there is something you should try and is helping me: it is rosemary extract. Im taking about 120mg rosmarinic acid a day and its helping my POIS a lot. People who did not respond well to niacin should definetely try it.
... For as long as I can remember, I have felt very weak right after the ejaculation and it takes me days to get back my energy, 4-5 days. In about 7-10 days after last ejaculation, I feel completely normal and energetic. Seconds after ejaculation, weakness takes over my body. I feel like ALL the energy has been drained out of me and I have absolutely no strength left in my body. I become completely lethargic and weak ...
Prolactin provides the body with sexual gratification after sexual acts: The hormone counteracts the effect of dopamine, which is responsible for sexual arousal. This is thought to cause the sexual refractory period. The amount of prolactin can be an indicator for the amount of sexual satisfaction and relaxation.
I also get nocturnal emmissions. But they don't cause any weakness. I have had nocturnal emmissions many times but no weakness after it.