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Guys, on dopamine:It's not the answer. I've tried everything you can do to modulate/upregulate/downregulate dopamine. Stimulants. Parkinsons drugs. Antipsychotics. And on and on. I've been through serious medical care for a period of 5 years because of mental illness, and I've had the opportunity to work with the best physicians out there. I've been seen at the National Institutes of Health here in the USA, and I had the ex-director of the entire inpatient center of the NIH (a psychiatrist) literally pull everything out of his hat to see what it would do dopaminergically.The dopamine theories of mental illness and mental health are old news. They are losing relevance in light of research that points to the brain working on neural circuits and specific pathways that primarily create good health or poor health.I personally found out just how important pathways are when deciding to undergo electroconvulsive therapy. It changed my life and SAVED ME from major depression. The repeated shocks and seizures formed new pathways that to this day are the main reasons I am thinking more about life and less about death!That's why I'm so excited about our research, it focuses on a nervous system dysfunction. Nerve tone is essential for your brain's communication with our body, and if our nerves are not toned, or "out of tune", you can get over or under stimulated. And with as complicated a nerve as the vagus nerve is (the one being studied), this means a LOT of things would go wrong, and that's what I believe we see with POIS.How can you help yourself with this approach/theory? Stimulate your body in a healthy way! It seems to me that ejaculation seriously disrupts the state of the nervous system. I have found for myself that if I engage in 1-2 hours of vigorous cardiovascular exercise (like biking or running), then I feel MUCH more peaceful. This would be explained by exercise's modulation of the autonomic nervous system. What else works? Meditation. Mindfulness meditation allows the brain and body to enter into a protective state, where you can handle anxieties more easily and identify sources of pain, physical and psychological. The more active I am, the better I do, and the more I sit in quiet contemplation on a regular basis, the more I can handle.I truly believe this has to do with engaging my body's natural mechanisms to regulate nerve tone.I think that vagal nerve stimulation has a lot of promise for us, and I look forward to some great work done in our study!IF YOU FIND THAT THOUGHTS OF DEATH AND KILLING YOURSELF ENTER YOUR MIND, PLEASE MAKE SURE YOU UNDERSTAND YOU ARE CONSIDERED MAJORLY DEPRESSED AND WOULD BE A CANDIDATE FOR ELECTROCONVULSIVE THERAPY. It IS safe. It IS powerful. Take my results as evidence. I was very scared going into it, but it HAS BEEN THE CHOICE THAT HAS SAVED MY LIFE. DON'T HESITATE TO ASK YOUR DOCTOR.But on a last note, I do find that anti-inflammatories help me deal with POIS. If I take NSAIDs before I ejaculate, I have reduced symptoms. BUT. NSAIDs are dangerous in the long term, and I have found a GREAT replacement in the form of curcumin, the active ingredient in tumeric root. Find a product that CONCENTRATES it, like Terry Naturally's Curamed or Curamin. I have been feeling less aches and pains, and my recovery times are faster.Best,Nightingale
Guys, on dopamine:It's not the answer. I've tried everything you can do to modulate/upregulate/downregulate dopamine. Stimulants. Parkinsons drugs. Antipsychotics. And on and on. I've been through serious medical care for a period of 5 years because of mental illness, and I've had the opportunity to work with the best physicians out there. I've been seen at the National Institutes of Health here in the USA, and I had the ex-director of the entire inpatient center of the NIH (a psychiatrist) literally pull everything out of his hat to see what it would do dopaminergically.
I forgot add one thing in my last post, tomorrow one day, I would watch and read, life after death videos with full happiness. Bye. Bye. to all
I decided to suicide myself as I am not able to tolerate the life. This is my death note.
Hello friends, I decided to suicide myself as I am not able to tolerate the life. This is my death note. If I provide my death note to people in my city, no body would believe what I am saying. Thatís why I am providing my death note to this forum, so that atleast you guys would trust what I a a m saying and there would be a peace to my soul. Reason for sucide is as belowAs posted in my previous post, people in my city are though that I am gay and they are spreading the message to all the people in the city. Further, my parents, my friends, my boss, my colleagues are under the assumption that I am Gay. With add to this, from the past several years, I am helping others too much and I am taking extra care of so many people and I am soft corner to all the people. Why I am doing this, for each help / each extra care / each soft care taking to others, I am praying with my god is that god please cure my POIS and see how I am helping to others. But people around me incluing my parents, my boss, my friends, thought that I am a gay and due to this, I am helping so much to others. But factually, as explained above, I am helping other because, I want to show god that how I am helping everyone and also with intention of my future business plant. Due to this my too much helping nature along with POIS symptoms, people misunderstand me and they thought that I am a gay. Initially, I have around 500 people who had trusted me. But as of now, I not had even a single person who will trust me. I not done even a single mistake / harm to others and not seen any of them sexually except for one girl I loved her and later as she rejected had a quarrel with her and told many lies in this area and also I not taken care my parents and neglected them. Apart from this, I have not done a single mistake / error / bad behaviour in past 6 years of life. However, I confess that in my childhood, i.e. around 10 years back, I have done few mistakes in my life and I realized those mistakes and I never did such a mistake. As explained in my previous post, my astrologer has identified my childhood bad behaviour and he believed that I carrying that behaviour now also and spreaded bad message to my family. He not understand how I changed from 2005 and doing only good things in life and not at all scold any one even if they do any wrong thing, how helpful to others in teaching, giving jobs, giving money, solving problems without any much expectation except praying god for my care and also my future business help. But, to all the people to whom I had helped, not understanding me. Thatís why I came to a conclusion that people like me i.e. very sincere, honest, good, too much caring person is not possible to live in this commercial life, as people had different thing in thier mind and even thgough I had done good work with the intention, would not understand. Thatsís why I am realized that I am become too much honest and it is not possible to live in this world and also not possible to facIe POIS. After my POIS cure, I had a dream of helping orphans. But now, I am leaving my life without achieving my objective i.e. to help orphans and unfortunately, now I am dying as a orphan even though I had so much of friends, parents etc and it is not of any oneís mistake. I also acknowledge my friends reaction to my behaviour as they are normaly commercial people and not abnormal like me where I helped too much to all that one no body would do in this era. So, I felt, my fate is not good and due to this, I am leaving my life at this young age of 26 and my death day is tomorrow late night i.e. between 25th and 26th morning or 26th afternoon. Further, people, due you know how I am going to die, I would take the tablets which I had experimented on body to cure my POIS and this time I would take bundled of tablets to die. 100% I know that I would go directly only to heaven as I have done so much of help to others. However, people in my city would believe that I would go directly to helll as they completely mis-understood me and god only knows my behaviour and what I am and why I am helping so much to others and because of my honest behaviour he is calling very early in my lifeFurther, while writing this and also while taking the tablets, I would be extremely happy and not at all sad as I am going to add and further I am satisfying so many peopleís wish as they want me to die. If I give this death note to my people, no body would trut, thatís why I am giving this note to this forum, so that atleast you would trust. I am humbly requesting you to pray for my soul to go directly to god and also, please pass this message to poiscenter.com. Unfortunately, I am leaving you people in the middle of the POIS research, sorry for the same as I promised so many people that I would be a part of the POIS cure team and I pray god to excuse for this mistake of me. Thanking you,Nathan
Check this out guys: http://ghr.nlm.nih.gov/condition/dopamine-beta-hydroxylase-deficiency
I know MTHFR inside and out, because I've worked with Dr. Lynch before and my work consists of researching (which I rarely do successfully nowadays bc of compulsive masturbation followed by POIS and low dopamine).I also suggest looking into COMT since you are familiar with 23andme. It will lead to adrenal burnout in the long run. Royal jelly will help increase BH4 production.Been there, done that. Vitamins, minerals from A-Z. Methyl B-s, digestive enzymes, probiotics etc.Nothing worked besides L-Tyrosine which gave me severe anxiety so I stopped it.
Now I suspect longterm iodine deficiency. So I decided to give it a shot, but it made my blood sugar problems worse. It is because my adrenals are out of whack and I'm in overdrive from the COMT.Going to follow this guy's dietary protein/carb ratio suggestions: http://ehealthforum.com/health/proteins-trigger-low-blood-sugar-t185956.html followed by megadosing of vitamin C (5-10 g /day), spending less time on the computer and going to bed earlier as well as limiting ejaculation. I've also ordered Skullcap and going to up my magnesium intake. If things will get better then I will give Iodine another shot. I think it's the root cause of my chronic anemia and it's worth mentioning.PS: Anyone tried taking glucose tablets before or after orgasm? How did it affect you?
I also suggest looking into COMT since you are familiar with 23andme. It will lead to adrenal burnout in the long run. Royal jelly will help increase BH4 production.
Nightingale,Good to see you back. I read your article on dopamine and I admire your guts in undertaking electroconvulsive therapy. I am glad that it is working for you. I remember that you have MAOA R279R (+) http://snpedia.com/index.php/Rs6323 Usually this variant causes dopamine level too high, and results in psychosis. Also this variant make it very hard for you to tolerate 5htp supplement, because you may quickly go from deficiency to excess on serotonin.There is a medicine that directly correct this problem for some people: http://www.respena.com/respen-A/respenAclinical.pdfthat increase MAOA activity specifically. Antipsychotic medicines typically just block dopamine D2 receptors in the brain without actually lowering the dopamine levels. I also recommend running this report on your 23andme results: http://www.snpedia.com/index.php/PrometheaseIt has lots of information on what medicine may or may not work for you due to your genetic make up. For example, my dad was able to switch to a more effective medicine for his bipolar disorder, after we found his genetics does not properly transport several SSRI over the brain-blood barrier, including the med he has been taking for years. Now he can take a much lower dose on a more effective med.Also, this diagram may be helpful to you to see what neurotransmitter you are deficient: http://en.wikipedia.org/wiki/File:NorepinephrineDopamineSerotonin.pngRomie S
Hello peoples.I have returned with a small bit of useful info.I have found a new regiment thats really helped me stave off unwanted nocturnal emissions.I consume one Monster Energy Java drink a day. Thats it. Now how does this work? Not sure why this particular energy drink is so potent, but it seems to noticeably "desensitize" one as well as lower the sexual urge. I used to use dream control and take a muscle relaxer etc etc. For whatever reason though drinkin one of those Monster Java energy drinks a day has made avoiding NE's so much easier. Im not gonna even begin to dissect the reason, I just know that it works fairly well. Also relieves minor aches and pains, this particular brand of energy drink, so might be helpful for those who have O'ed as well? Anyways, fight the good fight. Im out. Peace.
Hello all,As explained in my previous post, I attempted for bad thing on 26th, after taking those tablets, I realized importance of my life and our goal to remove POIS. Fortunately, I survived from my attempt and I was in ICU for two days and now back to normal life. Presently praying god for a good job as I lost my previous job. Thanks for the support provided to me. I would be back again on trying things for cure at the earliest.
Quote from: desperate man on 06/08/2014 12:53:40http://psychcentral.com/lib/the-vicious-cycle-of-adult-add-shame-and-compulsive-sexuality/000520that is me in a nutshell. haven't been porn surfing for some years now but i think it has alternated my mind significantly, never seen prostitutes thank god. i think my tinnitus boosted my problems significantly.my parents have never really acknowledged my talents, thats really a shame, they also made me isolated as a young adult.