Post Orgasmic Illness Syndrome (POIS)

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Offline rockytop

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20000 on: 03/04/2016 02:37:25 »
Hi,

This is my first ever post.  I think this forum provides fantastic support to all of us who suffer from this cruel condition......a condition which in normal circumstances is incredibly to talk about.

I have had what I presume is POIS for 20 years.  I guess compared to many of the other sufferers on this website I have a fairly mild version of POIS but my symptoms are still severe enough to have a huge impact and limiting effect on my life.  The main symptom associated with my POIS is burning, sore and puffy eyes.......to the extent that I just can't look anyone else in the eye when I am in my POIS state.  Lesser symptoms include mild brain fog and fatigue.  The veins on my arms also become slightly distended during my POIS state.  My symptoms last for the rest of day on which I O and the following day......the day after that I am POIS free.  Even if I pass a tiny drop of semen (without any kind of arousal) when peeing I get symptoms so I guess this would suggest that my POIS is of the allergic reaction kind.  I have had short term relationships but my condition prevents them from lasting beyond a month. 

I have tried a few treatments with limited success.  These include:

Niacin - reduces symptoms by around 80-90% when O after flush.  However, for me there is an unpleasant side effect from taking niacin where I repeatedly flush (often severe rosacea-like flush accompanied by eczema) for weeks afterwards so this is not really a treatment option for me.  It could be the Niacin is mobilizing heavy metals (primarily mercury) in my cells and this is causing the rosacea.

Probiotics - I read a paper which suggested that Lactobacillus casei could help modulate auto-immune responses so I bought a probiotic supplement which contained this strain.  For around 5-6 weeks these supplements completely eliminated my POIS symptoms.  After 5-6 weeks the supplements quickly lost their efficacy.  I have tried a number of different strains since but have not come that close to replicating my initial success.

Olive Leaf/fenugreek/garlic/Mucuna/DAOsin/theanine supplements - no effect

Herman's vitamin/mineral regime - I forget the exact protocol but consisted of manganese, copper, zinc, pantothenic acid.  This protocol did have a little effect.....around 30-40% reduction in symptoms after persisting with it for a few weeks.

Gluten free diet - no effect

Alcohol seems to reduce the symptoms significantly (70-80%) but I do not really see this is a realistic treatment.  I also had all of my mercury amalgam fillings removed just over a year ago and will monitor over the next couple of years whether there is any general improvement (am only chelating very very slowly with the occasional DMSA and/or ALA capsule)   My next treatment experimentation will involve Alpha GPC supplements.

Anyway, I would be interested to hear from POISers who have the same or similar symptoms and hear about the treatments they have tried.  My initial success with probiotics suggests that optimizing gut health can be an important part of any POIS treatment.

All the best
Rockytop

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20001 on: 03/04/2016 06:58:35 »
<former Moderator visiting periodically>

Just in case you're not aware, there is also another POIS resource named:

POISCenter






« Last Edit: 04/04/2016 16:55:35 by demografx »

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Offline happy2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20002 on: 05/04/2016 18:43:20 »
Vincent M,
The benadryl actually winds me up, doesn't make me sleep better.  It does that with some people.  To answer your question, the 2 benadryls IMMEDIATELY following O, and Zyrtec every day, completely knock-out my POIS symptoms.  It used to be I'd get it, like real bad, for 3 1/2 days like everybody else, then crash on days 4 and 5 with fatigue.  Now, all I have to deal with is the benadryl hangover day 1.  The brain-fog, and all other symptoms, either cognitive or physical are completely GONE.  I wake up day 2 feeling completely normal; no brain-fog, joint-pain, or fatigue and most importantly, no POIS.   It's worked for me [:)].  I previously suffered from POIS for 20+ years.  I'm now 35 years old.  Symptoms got REALLY bad when I was 21.

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20003 on: 06/04/2016 21:34:50 »
Vincent M,
The benadryl actually winds me up, doesn't make me sleep better.  It does that with some people.  To answer your question, the 2 benadryls IMMEDIATELY following O, and Zyrtec every day, completely knock-out my POIS symptoms.  It used to be I'd get it, like real bad, for 3 1/2 days like everybody else, then crash on days 4 and 5 with fatigue.  Now, all I have to deal with is the benadryl hangover day 1.  The brain-fog, and all other symptoms, either cognitive or physical are completely GONE.  I wake up day 2 feeling completely normal; no brain-fog, joint-pain, or fatigue and most importantly, no POIS.   It's worked for me [:)].  I previously suffered from POIS for 20+ years.  I'm now 35 years old.  Symptoms got REALLY bad when I was 21.
can you post your result in poiscenter.com, i believe others should try it. The effects on my fatigue were just to profound. I would have posted there but i think the system there is having problems, it deleted my account and wont let me create another one.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20004 on: 07/04/2016 01:12:58 »
CertainlyPOIS, I'm really sorry you experienced that!!

Please send me your IP and we'll try to get you back in!


« Last Edit: 07/04/2016 04:19:08 by demografx »

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20005 on: 08/04/2016 00:47:34 »
CertainlyPOIS, I'm really sorry you experienced that!!

Please send me your IP and we'll try to get you back in!




I should have contacted you already buy I dont have stable internet right now. when i do, i will send you an ip address.

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Offline happy2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20006 on: 12/04/2016 04:03:36 »
CertainlyPOIS,
I just saw you posted.  I'll try posting on POIS.com.

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Offline gogetter

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20007 on: 17/04/2016 00:32:38 »
Dear  all
Thank you so much.
I have now spent almost a week since I have discovered this forum here and at the poiscenter, browsing and reading whenever I have a few minutes.
I'm in awe and disbelief, how many people suffer of this illness. I am even more shocked HOW most Doctors have STILL never heard of it. You guys have done so much research and experiments all on your own Kudos to that. I am grateful at the same of the people who are generous in sharing their findings in order to help others. To each single one of you and especially to the moderators and repliers I say Thank you from all my heart.
As most POIS'ers I have done the usual runaround to the doctors, I have also met with an iridolgist an energy healer and finally a competent kinesiologist, All of them having absolutely no clue to this syndrome.
The last time I visited my GP he sent me for a blood test to check my testosterone levels among other things. (which I though was quite intelligent and non judgmental of him. I surely appreciated him looking into it seriously) My testosterone levels came back fine albeit slightly low; Therefore, I am wondering though how wearing testosterone patches would be of any benefit?.
I have ordered Niacin and am hoping to get it by Monday and start experimenting with that right away.
I find this Forum quite overwhelming to the amount of information available yet the lack of organized subcategories. I wish I could just type in search box how often and best time to use Niacin and then get a whole bunch of posts from various people relating specifically to the use of Niacin; Though, I realize it may be my lack of experience/skill using search on Forums.
Finally I want to share my experience that I have been a Pois sufferer since my early 20's though I have had brain fog much earlier. I am now 42 and I have been getting sharp pains in the tip of my penis noticed during intercourse. It is only when this started happening that I have started taking my POIS seriously again and realized this is not just a  psychological or spiritual disorder.
 Unfortunately I am not seeing much talk of this particular symptom in this forum aside of the burning semen syndrome which war veterans have described having. I am not a war veteran nor I do not eat canned tuna therefore how am I getting mercury in my system?
Has anyone else had this sensation almost like someone is poking the tip of your penis with multiple needles? (strange I realize)
As far as the illness is concerned I am at the end of my tethers; Though, as far as treatment is concerned I am right at the beginning of my journey, so I am still hopeful. I am also very much looking forward to the result of the NORD team and or the Rutgers university study to see what treatments they come up with.
In the meantime any replies with tips suggestions or links to recent information are most welcome.

Thank You all again
Gratefully, GoGetter


PS:  Can anyone come up with tips on how to navigate the website? How to find multiple collection of answers on a treatment without having to sift through tons and tons of individual posts would be great.
« Last Edit: 17/04/2016 01:04:46 by gogetter »

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Offline iLikeScience

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20008 on: 17/04/2016 20:26:21 »
Hello,

I'm new to this forum. Was wondering, found out last week that there's a medical term called 'hyperspermia' (see wikipedia)
Have not heard of this term before, maybe its rather new. Could there be a relation between the semen volume and POIS ?
maybe this is discussed before on this forum...

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Offline Scarysheep

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20009 on: 18/04/2016 22:07:27 »
I wish I could just type in search box how often and best time to use Niacin and then get a whole bunch of posts from various people relating specifically to the use of Niacin; Though, I realize it may be my lack of experience/skill using search on Forums.

gogetter, have you checket out the POIS forums yet? www DOT poiscenter DOT com/forums/index DOT php (No posting links, so replace DOT with .)

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20010 on: 25/04/2016 00:41:24 »
<former Moderator visiting periodically>



PS:  Can anyone come up with tips on how to navigate the website? How to find multiple collection of answers on a treatment without having to sift through tons and tons of individual posts would be great.


In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 posted results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.


« Last Edit: 25/04/2016 00:45:29 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20011 on: 29/04/2016 17:17:37 »
<former Moderator visiting periodically>


On Apr 29, 2016, at 7:42 AM, Jacqueline Kraska/NORD wrote:

Hi demo,

Sorry it has taken some time but please find attached the public section of the 3rd scientific report, which was the same as provided in the section 2 for our reviewers called "accomplishments"...

All the best,
Jacqui

--
Jacqueline Kraska
Research Programs Manager
National Organization for Rare Disorders

===============================



"Based on the 97 respondents (mean age: 33.5 years) summarized in the attached Table, a clear picture emerges of the age of onset of POIS symptoms as being in adolescence (mean: 18 years of age), that POIS symptoms can be triggered by self- or partner erotic stimulation that does not necessarily involve intercourse. Penile stimulation is the most prevalent inducer of POIS symptoms compared to rectal or prostate stimulation. The POIS symptoms that are most prevalent are: “Brain fog”, lack of concentration, and fatigue, each of which symptoms were reported by at least 82% (80-83/97) of the respondents. These three symptoms are also the most severe, as indicated by a Likert scale (i.e., subjective rating of severity on a scale from 1 to 10 with 10 being the most severe possible). In order of decreasing intensity, the most prevalent symptoms are: “Brain fog”, lack of concentration, fatigue, depression, irritability, anxiety, headache, and nausea. These range from brain fog, with a mean intensity of 7.6 out of a maximum of 10, to nausea, with a mean intensity of 4.8. The mean durations of these symptoms were reported to range from 2.8 to 5 days (mean = 4.4 days). Somewhat surprising to us, and which will require a slight modification of our protocol, is that the latency of onset of these eight POIS symptoms ranged from 2.2 to 3.7 hours (mean = 3.1 hours). We now will continue our recordings in the laboratory for at least 4 hours post-orgasm, as the latency for the POIS symptoms is evidently longer than we were led to believe originally. It is clear from this summary table that POIS is reliably characterized by a highly distressing cognitive and physical state that starts within a few hours after orgasm and persists for days. We plan to publish these findings, which we trust will raise awareness of this distressing condition. We hope that the vagal tone component of our research will reliably shed light on the cause, and suggest therapy, for POIS. We already are seeing, as presented in our progress report submitted December 13, 2015, that after orgasm, the HRV index is relatively low compared to resting and exercise. If our continuing research shows this to be a reliable phenomenon, it suggests that procedures designed to reduce vagal tone may be effective in counteracting or preventing POIS symptoms."







 
« Last Edit: 29/04/2016 20:59:11 by demografx »

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Offline meteo74

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20012 on: 18/05/2016 17:32:04 »
<former Moderator visiting periodically>



PS:  Can anyone come up with tips on how to navigate the website? How to find multiple collection of answers on a treatment without having to sift through tons and tons of individual posts would be great.


In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 posted results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.



I always write just 2 words (post orgasmic) in google..

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20013 on: 19/05/2016 05:26:34 »
<former Moderator visiting periodically>



meteo, yes, but that does not give you 1) only the category you are interested in -- 2) within this thread at Naked Science Forum.

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Offline bruxe

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20014 on: 22/05/2016 20:11:41 »
« Last Edit: 22/05/2016 20:13:50 by bruxe »

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Offline nathan123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20015 on: 21/06/2016 13:10:28 »
Hi All,

Hope all are doing well. It has been two years after I am posting in POIS. As mentioned earlier, I got cure from POIS from the past two years and now leading a healthy life. For immediate relief from POIS, please do the following technique whenever you are in POIS and you will be surprised and will get cure from POIS.

Whenever you are in POIS, please massage top of toes of each finger of your legs for two to three minutes and you will be immediately out of POIS. When you are in POIS, our brain chemistry would be imbalanced. Massaging top of our toe would produce production of Serotonin and also activate the brain.   Within twenty minutes and without any cost, you all can come out of the POIS. Try this technique and give me the feedback. Suggestion is to massage hardly the top of the toe or you can also use the massager.

thanks & regards,

Nathan.

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20016 on: 22/06/2016 09:24:44 »
Has anyone here tried Happy2's anti-histamine treatment and been disappointed? 
We have one person who has tried it and has replicated his successful results.  The active ingredient in Benedryl was not easy to find in products in my country but I tried a syrup with it in it, and was disappointed. I recently discovered it has much less than 2 Benedryl and also recently discovered Snuzaid is available OTC and has 50mg diphenthydramine in it so will give it another go with that med. Hopefully it does not make me really groggy like some other 1st generation anti-histamines. Second generation anti-histamines like Zertec, Claritone worked well with hay fever days but did nothing for pois.

I wonder why an allergic response to orgasm if that is the case wipes many of us to various degrees for so long (4-5 days) yet a day out in spring pollen weather for a susceptible person  does not wipe them out for anything like that length from a short term exposure. Has anyone here who has had genetic testing done, can confirm if they have mutations in the genes related to DAO production (used to block histamine)?   I see Rocktop a few posts above tried DAO supplement and it did nothing to help him.

Happy2 - did you used to get dark circles around your eyes, photosensitive, skin deterioration/rash or dandruff post O prior to Benedryl/Zyrtec?

I was going down the path of heavy metal detoxing as solution, but it has become difficult. Initially I thought it was helping reduce symptoms somewhat (only when on chelator then I would crash a little off cycle). I am getting bad face eczema/dermatitis when I do now even at low doses of chelator, which is a real shame as it would seem that is quite likely a sign of detox but at the same time who wants to look like they are sunburned all the time.
« Last Edit: 22/06/2016 10:22:04 by acronym »

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20017 on: 22/06/2016 09:38:50 »
Demo
Is the second part of the 3rd Nord report coming out later in the year?
It is great to have Nord officially document pois and its symptoms, but for us on this forum that info so far is nothing new. Have you been given info on what the MRI scans showed? 
Ultimately though for us, unless the scans can give a clear indication of a weakness/defect that has a proven therapeutic path to treatment that has been used with other conditions showing the same, then its going to be just a stepping stone to more (and not so simple) research needed down the line.

Q - You are on TRT. Do you take HCG as part of that (most docs dont know or care about it)?  What about an anti aromatize inhibitor or are your Est levels well under control?  Just curious

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20018 on: 08/07/2016 01:47:35 »
<former Mod visiting periodically>


HI acronym,

•The 4th & final report will be out mid-September.

•No fMRI or tVNS study info has been released yet. Probably will not until final publication.

•I'm only on Androderm TRT, 4mg daily. Nothing else.


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Offline Bulbo

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20019 on: 10/07/2016 11:12:49 »
Hi guys
I am going to post my progress. I have been eating 2 backyard hen's eggs a day for 1 year 5 months and 23 days. My pois was of a type where brain fog does not go away after an o meaning it was present always. After starting eggs i found my pois duration was 5 or 6 days. By Jan 14, 2016 POIS duration became 2 or 3 days. By the next three months pois duration should have reduced to 1 or 2 days, but it didnt happen. But unfortunately by March 10, 2016 every time i o my pois lasted for 6 days. This 6 day POIS lasted everytime i o from march 10, 2016 onwards. I was very desperate. Those days were very tough. But by June 6, 2016 my POIS duration all of a sudden became 1 day. I am so happy guys. At last POIS duration became 1 day.

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20020 on: 13/07/2016 23:14:25 »
Update:
I have been abstinent for a long time but recently had an orgasm and did not have any POIS. Prior to this event I was taking some supplements, the most significant of which might have been Black Elderberry extract capusules. When I first started it I experienced sensations in the pubic region (under the skin), something akin to occasional vibrations. I don't know what was going on but I wondered if it might be the reaction of the Elderberry fighting a latent virus of some kind. It perhaps sounds odd but Elderberry is purported to be an anti-viral, among other things. So I stayed on it until the sensations went away and then went off it. Then a few weeks later I started it again prior to orgasm and then continued on it for a couple of weeks.  During this time I did not experience any of my prior POIS symptoms. I am considering the Elderberry to be the most likely cause of the positive results.

I will also mention the other supplements I have been on during this time in case they are significant: turmeric capsules and ALA (alpha lipoic acid).  The turmeric is taken for general health, and the ALA was being taken for potential benefits of chelating heavy metals from my system. This was because I did a heavy metals urine test last fall and was told I have statistically elevated levels of mercury and lead (relative to the general population) .

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Offline B_Jim

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20021 on: 14/07/2016 17:15:48 »
Welcome back John !

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20022 on: 15/07/2016 11:07:17 »
Thanks B_Jim  : )

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20023 on: 22/07/2016 23:39:34 »
Update:
I have been abstinent for a long time but recently had an orgasm and did not have any POIS. Prior to this event I was taking some supplements, the most significant of which might have been Black Elderberry extract capusules. When I first started it I experienced sensations in the pubic region (under the skin), something akin to occasional vibrations. I don't know what was going on but I wondered if it might be the reaction of the Elderberry fighting a latent virus of some kind. It perhaps sounds odd but Elderberry is purported to be an anti-viral, among other things. So I stayed on it until the sensations went away and then went off it. Then a few weeks later I started it again prior to orgasm and then continued on it for a couple of weeks.  During this time I did not experience any of my prior POIS symptoms. I am considering the Elderberry to be the most likely cause of the positive results.

I will also mention the other supplements I have been on during this time in case they are significant: turmeric capsules and ALA (alpha lipoic acid).  The turmeric is taken for general health, and the ALA was being taken for potential benefits of chelating heavy metals from my system. This was because I did a heavy metals urine test last fall and was told I have statistically elevated levels of mercury and lead (relative to the general population) .

what brand and dosage are you using.
Dont you think your abstinence might have a big effect on why you dont have any symptoms.
I know if i am abstinent  for  just a mont,  sysmptoms from one orgasm is not that bad.   Pois only comes to full form when i do multiple orgasms.

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20024 on: 25/07/2016 21:31:23 »
I started with Sambucol Black Elderberry Syrup which is 1.83 grams of concentrate taken 4 times a day. After that I changed to a capusle supplement of 1g concentrate taken 4 times per day.

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20025 on: 25/07/2016 21:50:20 »
I started with Sambucol Black Elderberry Syrup which is 1.83 grams of concentrate taken 4 times a day. After that I changed to a capusle supplement of 1g concentrate taken 4 times per day.

thanks

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20026 on: 27/07/2016 10:55:30 »
Whether abstinence might have been a factor I don't know. It is possible I suppose but I rather doubt it.

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Offline Wordist45

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I am a 71 year-old male in peak physical condition. (I came in 3rd in my age group in a recent 5k run.) I never experienced POIS until I began practicing Tantric sex with the same partner. Including foreplay, the time to ejaculation could be from 30 minutes to an hour or more. A couple of hours later I will experience debilitating weakness and brain fog. The longer the period of sexual stimulation the longer and deeper the dysphoria, which usually disappeared by morning.

Today I found a possible solution, a combination of 50 mg 5HTP with 25 mg DHEA. Within 15 minutes of administering the dosage I feel much better.

Is it possible that this prolongation of sexual stimulation caused the release of excess endorphins, and the absorption of oxytocin received via the exchange of saliva through kissing and vaginal-penile contact?







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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20028 on: 31/07/2016 17:10:13 »
Why did you choose this combination? Isn't 5HTP for sleep and DHEA for heavy metal chelation?

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Offline Wordist45

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20029 on: 31/07/2016 20:36:23 »
John21: "Why did you choose this combination? Isn't 5HTP for sleep and DHEA for heavy metal chelation?"

On the theory that the POIS malaise is caused by the depletion of serotonin, dopamine, endorphins and other "feel good" neurotransmitters, I chose both supplements because of their effect on serotonin and these other neurotransmitters. Multiple sources reported that 5HTP is a serotonin precursor, and I've taken it for years for depression in doses ranging from 50mg to 300mg daily. (Presently I take 100mg daily.)

DHEA I've been taking for years for adrenal fatigue (stemming from severe childhood trauma) in daily dosages from 25mg to 75mg for prohormone replacement, with amazing positive effects on mood, libido and energy. (Presently I take 75mg daily.) DHEA is concentrated in the brain and throughout the nervous system; so I postulated that it, too, should have a positive effect on serotonin depletion.

Here I am the next day, less that 24 hours after my POIS episode, feeling great. I ran 3.1 miles this morning and feel great.

I am including a chart showing the position of DHEA in the chain of Steroidal hormone pathways.

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Offline Wordist45

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20030 on: 01/08/2016 00:30:07 »
Wikipedia's Hormone Hypothesis fits what I have described above:

quote--
According to another hypothesis, POIS is caused by a hormone imbalance, such as low progesterone,[7] low cortisol, low testosterone, elevated prolactin, hypothyroidism, or low DHEA.[16]

POIS could be caused by a defect in neurosteroid precursor synthesis. In this case, the same treatment may not be effective for different sufferers. Different sufferers may have different missing precursors, ultimately leading to a deficiency of the same particular neurosteroid, causing similar symptoms.[7]
--unqoote

[7]  Dexter S (Feb 2010). "Benign coital headache relieved by partner's pregnancies with implications for future treatment.". BMJ Case Rep. 2010:
[16]  Attia AM, Yasien HA, Al-Ziny MH (2013). "Post-orgasmic illness syndrome: a case report". F1000Research 2 (113). doi:10.12688/f1000research.2-113.v1.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20031 on: 03/08/2016 20:28:27 »
<former Mod visiting>




Hi, all!

Things are slow in POIS ResearchLand...nature of the beast :)

Hope some of you have found some POIS relief -- at least partial -- from the many good ideas bandied about here.

HOPE TO HAVE SOME POIS NEWS IN MID-SEPTEMBER!

BEST wishes,
Demo

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20032 on: 03/08/2016 20:30:25 »





Congratulations to John21,  B_Jim and CertainlyPOIS for nearly 10 years POIS forum participation!

(Sorry if I missed anyone else!)





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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20033 on: 03/08/2016 20:36:36 »

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20034 on: 06/08/2016 01:03:35 »
Wow it has been that long! Thanks Demo!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20035 on: 06/08/2016 20:20:34 »
🙂

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Offline akt1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20036 on: 22/08/2016 21:49:22 »
Hey you guys,

Im a sufferer from this #¤%&&%.
Niacin has given me great relief.

I believe I do suffer from a general serotonin deficiency, which might run in the family. bad receptors or something, dont know.

Tryptophan, as you well might know, is the precursor to serotonin. Though, if one is deficient in niacin, it takes 60g tryptophan to produce 1g niacin in the body.. instead of serotonin. Which might mean that you do not get that much serotonin from the tryptophan.

I take like 200mg niacin pre o, and some afterwards.. and i also take whey protein - which is a good source for tryptophan as well as other amino acids. So, with this formula i get; niacin + tryptophan -> serotonin naturally.

I do not want to rush things, but the pois is gone for me.
I also feel harmony, relaxation, good mood when I take this when needed in general.

niacin + whey protein has proven, at least from how i see it, to provide me with serotonine when needed.

- I take this when I start to feel "mentally negatively strained" in everyday life, and also after O and also the day after alcohol.
Earlier i got panic attacks the day after alcohol, niacin has taken away this. My theory is that it all boils down to a serotonine deficiency which is "killed" with niacin and tryptophan for me.

Hope this can contribute in some way.
I might be wrong, but after lots of trial and error, this is where im at right now.


cheers

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Offline akt1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20037 on: 23/08/2016 17:06:36 »
Update:
200mg niacin + whey protein (500mg tryptophan) pre-o -> no pois

Theory:
Niacin and tryptophan prevent serotonin defiency/depletion after O.

peace out
akt1

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Offline akt1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20038 on: 24/08/2016 23:10:25 »
Could it be that niacin helps to make tryptophan available as serotonin?
-The niacin flush metabolises available tryptophan in the body and creates serotonin?

So if one adds extra tryptophan (for example whey protein) then it is granted that tryptophan is available when niacin is used.
in case this is a question about serotonin..

I believe whey protein (o,5g tryptophan among other amino acids) and niacin has helped me after o as well.

regards

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Offline akt1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20039 on: 25/08/2016 07:53:25 »
Update2

The anti-pois effects was probably due to niacin.
Nacin and whey (tryptophan) does give relief also though. Relaxation and presence.

Does anybody else feel like their brain starts to live its own life when hit by pois?
You get almost disturbing nightmarish thoughts out of nowhere?

Feels again more like an inflammation problem..
200mg niacin/nicotinic acid pre-o seems to work wonders though for me.

Wish you all success with this "#¤%.

Best regards

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Offline akt1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20040 on: 26/08/2016 23:42:44 »
update3 :)

Still, there is something going on..
I only took 50mg niacin in the morning and then 2 portions of whey during the day.
Had an O in the evening. Got some pois symptoms; could not sleep, disturbing thoughts, anxiousness.
Took niacin and whey in the morning the day after - zero pois.. usually my pois lasts for messed up 2-3 weeks or something.
Feels as if im able to kill pois after o with whey and niacin..
niacin pre-o is always good though - takes away symptoms after o.
So niacin pre-o and whey and niacin after o, that will probably fix it for me..

My why contains about 18 amino acids i believe, where tryptophan is one of them.

Have a good evening
Akt1

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Offline akt1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20041 on: 27/08/2016 23:43:20 »
Still wondering if pois has something to do with serotonin depletion.. since that seems to be sort of an epidemic in our time.. SSRI being one of the most commonly prescribed drugs.. But maybe ssri has been experimented with here.

Niacin and whey (including tryptophan) are supposed to provide serotonin naturally..

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Offline duke0knight

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20042 on: 05/09/2016 05:34:47 »
Below are my 2 articles about how I cured myself from POIS.
This was my article about POIS in August of 2015 (below that article is my article a year later in September of 2016):

 POIS NATURAL HEALING:

I was lucky that I suffered from Post Orgasm Illness Syndrome for only 6 months until I found a natural way to heal myself on my own. I have searched everywhere online and have heard that POIS is not curable at the moment and that the only solution so far is to inject people with their own semen because doctors think that we are allergic to our own semen (I dont think that is the case or at least not in my case).

 I AM NOT A DOCTOR so please do not rely on my advice 100%. Many of my statements probably arent 100% accurate but roughly I think they are correct and they did cure me from POIS. I have only been POIS free for the past 20 days (but I had orgasm every night and worked in my office 6 days a week, 11 hours a day - pretty tough on a body and yet NO POIS SYMPTOMS) so Im still not 100% sure that all of these things that Im naming here below work but I just really want to hurry and not wait longer and help people out there who still suffer. In case I do discover some more relevant knowledge about beating the POIS I will write back here or on some other blog UNDER MY BLOG NAME "DUKE0KNIGHT."

From what I have learned after trying for months to cure myself is that all my troubles originated in my stomach and my Adrenal Glands. The CURE was to REDUCE the amount of CORTISOL AND ADRENALIN in my body throughout the day and especially in the seconds immediately after my orgasm:
- too much stress raises the levels of cortisol and adrenalin
- if you are stressed all day long your levels of cortisol and adrenalin are high and your Adrenal Glands keep producing cortisol and adrenalin even during night (because they are used to producing it and just cant stop producing it that easily) so that is why many of us cant sleep well during night. I had NO IDEA that I had stress and I never believed in it. It just sounded stupid to me but I learned that STRESS is very present in our lives and really damages our bodies.
- YOGA helped me a lot. I go to yoga 3 times a week. At first I didnt want to go to Yoga because its boring but after doing it 5 times I started recognizing how bad my breathing was and how stressed I actually was during the day. I believe that through correct breathing we reduce stress and therefore we REDUCE CORTISOL AND ADRENALIN which are the MAIN REASON FOR POIS. I also did Infra Red Sauna 20 times but I dont think it helped me that much.
- if you think about it the symptoms that you get after an orgasm (or at least thats  how I feel) are very similar to the body feeling after a big stressful moment in life and/or very low immunity and/or getting a flu. THIS IS WHAT helped me realize that CORTISOL AND ADRENALIN are the main reasons for my POIS. Cortisol and Adrenalin are being excreted DURING ORGASM.
- the only natural ways of reducing Cortisol and Adrenalin I could google online that worked for me were:
- Yoga
- A bunch of herbs that REDUCE Cortisol and Adrenalin and INCREASE MELATONIN (Melatonin is very important because it fights agains Cortisol and Adrenalin): HOLY BASIL LEAF, ST JOHS WORT, ASHWAGANDHA, MACA ROOT, KAVA, VALERIAN ROOT, REISHI MUSHROOM.
- make your room PITCH BLACK DARK when you sleep because that helps elevate the levels of MELATONIN. Melatonin is great and you need a lot of it to fight away Cortisol and Adrenalin. The sunlight or indoor light (bulbs, computers, cellphones, etc.) reduces Melatonin in our bodies and that is why we need to keep our bedrooms very dark (cover windows, cover door holes, and take out computers and cellphones or at least put them further away from your bed).
- try having 8-9 hours of sleep and try falling asleep BEFORE 12AM because Melatonin is being produced I think starting at 10pm so you dont want to miss those hours being awake.
- Immediately after orgasm (literally a second after you have an orgasm start doing heavy Yoga style breathing to reduce the excretion of Cortisol and Adrenalin. Try to relax your entire body by breathing and reducing the Cortisol and Adrenalin excretion. During orgasm Cortisol and Adrenalin are being excreted and that is BAD. Im not sure about this breathing thing but I think that it does help me. The thing is that the moment I realized that it is Cortisol and Adrenalin what causes my POIS I hit Cortisol and Adrenalin from all sides with multiple approaches (Yoga, herbs, sleeping on time and for 8-9 hours, breathing after orgasm, etc.) so now I dont know which one of them are actually working and which ones arent that important.

Final thing that I did was get a nutritionist to help me. Im not sure how instrumental she was but she definitely helped me with my stomach issues. Bad stomach issues can also lead to STRESS in your body and we all know now that STRESS EQUALS CORTISOL AND ADRENALIN.
After doing hair mineral test, blood micronutrient test and blood spot test (this is the list of those tests but I think you can do it through any other company that does the same thing: arlok dot com, greatplainslaboratory dot com/home/ , spectracell dot com)  she has shown me that there were multiple imbalances in my body (for example I had too much copper, aluminum and mercury, lack of zinc, etc.) and taught me how to eat well. Her website is: nourishholisticnutrition dot com but you can also go to any other legit natural healing nutritionist and Im sure they will be helpful.

I REALLY hope that some of you will be cured from POIS by following my advice.
Please, email me at duke0knight AT gmail DOT com if you have any questions and I will do my best to answer them.

Thanks,
______________________________________________________________________________

 This was my article about POIS in September of 2016 (a year after my first article):


My POIS is completely gone. The key was to work on strengthening my adrenal glands. The main things that helped me fix my adrenals were:

- Dr. Lam in California who gave me many of his natural tinctures and advice. His wife Doreen was the one who consulted me and it cost me $100 per consultation. I did a consultation every week in the beginning and then every month and now every 6 months.
- Physical therapist Shawn Phillips in Los Angeles gave me a lot of good nutritional and exercise advice since he already had issues with adrenal fatigue.
- Hot yoga helped me immensely as well. I feel that doing yoga 1-2 times a week works best for me.
- At my worst I tried not to do any heavy and intense physical exercise so I did walking and running, light weights with not too many repetitions and light boxing. After I felt better I started increasing the intensity and now I have almost reached maximum intensity in all those exercises.
- I fall asleep before 11pm every night almost. This enables me not to lose melatonin production (which our bodies produce from 10pm to 2am) and allows me to have a good night sleep. Lack of sleep, insomnia, etc. also damages adrenal glands heavily. At my worst, I had to take triple the dosage of melatonin pills (the healthiest sleeping aid out thereI guess) just to fall asleep. They helped me a lot and now I dont need them at all.
- At my worst I took out all the SUGAR and lowered CARBS in my diet. That was insanely helpful. Now I do carbloading weekends, which means that I eat as much sweets and carbs (bread) as I want. But my body is healthy now and can take this.
- Finding a sexual partner, girlfriend, wife, etc. would definitely help. The key is not to simply stop ejaculating. For me once a week ejaculation was working well and now I can do 2-4 ejaculations on many weeks, which I feel like is very normal for a guy like myself, in his 30s. I do have a sexual partner now and Im not watching any more porn. I feel that porn actually really messed me up since I watched it every night almost from age 13 to 30.
- Meditation helps me tremendously (especially right after sex or heavy exercise when I meditate for 10min-20min). I meditate 1-3 times a day. The goal for me is always to meditate 20 min in the morning and 20 min 4 hours before sleep but that isnt often possible so I take 5min or 10min whenever and wherever I can (at work lunch room, park, any peaceful place, etc.) and do my best and this brings me great results. It helps me with sleep and lowers my daily stress significantly. My meditation technique is very simple (exactly like this one: www DOT youtube DOT com/watch?v=rqoxYKtEWEc ). I lay down or sit (mostly lay down) and breathe. I think about my breath going in and out of my body. If any other thoughts come in I slowly try to put them a side and go back to thinking about my breathing. After 5min or 20min of this Im done with meditation. Meditation is boring but the effects are so awesome that I keep doing it. Dr. Lam's deep breathing exercises are also very helpful during meditation (breathe in deeply and slowly through your nose and feel your stomach and then lungs expanding, hold the breath for a bit and then breathe out again through your nose slowly and feel your lungs and stomach contracting).
- Tons of water. I drink 80 to 100 ounces of water a day. But I am careful not to drink a lot of water 30min before food and 45 min after food because water can mess up digestion. I do sip a bit of water though sometimes during meals to soften the food.
- Herbs that helped me (they can all be found at Wholefoods, Lassens, Sprouts, Amazon and other stores):
- Tons of Vitamin C (we urinate out all the Vitamin C that our body doesnt need) - great for immunity and adrenal glands
- Echinacea tincture - great for immunity and adrenal glands
- Beet juice and also all other organic fresh squeezed juices - increase significantly my number of bowel movements. I drink these juices in the morning, right after Ive had 22 ounces of water on my empty stomach. This almost always guarantees a bowel movement within an hour or two.
- Double the amount of normal dosage of Magnesium pills also helped me tremendously and increased the number of bowel movements. However, at my current stage I dont use any more Magnesium pills since I feel much better and my bowel movements are regular. At one point I noticed that probably because I was taking so many Magnesium pills I had diarrhea so I stopped taking them at that point. Diarrhea was a signal that my body has recouped all of its missing magnesium and there was no need for more pills, so I stopped.
- Dr. Schulze's Ginseng Tincture and Heart Tincture ( www DOT herbdoc DOT com ) helped me tons with my adrenal glands.
- Dr. Schulze's Formula 1 helped me with my bowel movements. I would take these pills only when I was very constipated and I would not rely on these pills long term.
- Probiotic pills and digestive enzymes (Im not saying everyone needs them but they did help a bit).
- My current state is that I dont need to use almost any more supplements/herbs/tinctures. I only use supplements if I notice that my adrenal glands are not doing well. Once they are better again, I stop using supplements/herbs/tinctures.

This is roughly my current update as of 9/4/2016.


Hello again,

Can anybody say they are 100% POIS cured. The answear at this stage is still a big NO. Every so often somebody comes up saying do this and that and you cured. CURED is a big word when it comes to pois. If you come on this website or any other POIS forum and you say you cured we only just might start believing you if you have managed to explain what exactly you been going through all these years with POIS. In my opinion even every vitamin, mineral, extract, med, whatever you try always has its pros and cons but it never quiet comes down to a permanent solution. More than likely only the scientists will solve this mistery.

As soon as I can I'd like to elaborate a bit further on my testosterone experience but just 1st want to try get pen and paper so I can also explain this to my doc in the best possible way. Deciding on using TRT sure is a bit of a daunting task when you dont understand it all, besides never mind convincing your doc.  [|)]




Hi 4everfogged

*I beleive no one has cured from pois.
**I think that no one can fined acure for pois except a sick doctor with the same illness,

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20043 on: 07/09/2016 08:25:35 »
Still wondering if pois has something to do with serotonin depletion.. since that seems to be sort of an epidemic in our time.. SSRI being one of the most commonly prescribed drugs.. But maybe ssri has been experimented with here.

Niacin and whey (including tryptophan) are supposed to provide serotonin naturally..
With the whey powder you are taking how many mgs of tryptophan are you taking (just curious)? Will you experiment with just tryptophan powder?  Maybe one of the other amino acids is a big deal too. Glycine on empty stomach at night helped me a little with symptoms.
As for ssri's I would not say it is necessarily indicative of serotonin depletion epidemic. Doctors will prescribe ssris for depression regardless if it is caused by nutrient deficiency or hormone imbalance or if you are low in gaba, dopamine, acetyl chloline, endorphines, etc.
« Last Edit: 07/09/2016 08:30:48 by acronym »

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Offline akt1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20044 on: 07/09/2016 21:17:01 »
Here are The amino acids (swedish):
100g and 30g portions.

Aminosyraprofil per 100 g och per portion 30 g.
L-isoleucin*   5,25 g   1,58 g
L-leucin*         8,39 g           2,52 g
L-lysin          7,06 g     2,12 g
DL-metionin   1,75 g   0,53 g
L-fenylalanin   2,58 g   0,77 g
L-treonin           5,13 g     1,46 g
L-tryptofan   1,45 g   0,38 g
L-valin*   4,87 g   1,46 g
L-histidin   1,26 g   0,38 g
L-alanin   3,85 g   1,16 g
L-arginin   1,88 g   0,56 g
L-asparaginsyra   8,88 g   2,66 g
L-cystein   1,92 g   0,58 g
Glutaminsyra   13,57 g   4,07 g
Glycin   1,30 g   0,39 g
L-prolin   4,28 g   1,28 g
L-serin   3,30 g   0,99 g
L-tyrosin   2,08 g   0,62 g
Total halt protein
-varav BCAA    78,80 g
18,51 g   23,65 g
5,56 g


I took this and niacin before and after o, and i had no pois.
Like 200mg niacin and whey pre o, 100mg The day after plus a wheydrink.
That made me get away with no pois.
Started to feel *#%% pois-bad The day after o, but niacin and whey (or maybe only whey)
Killed that state. Will try to elaborate some more, but i regularly do nofap.
Hope sincerely that it might help someone.
(I take natural whey without artificial sweetener, thus no fenylalanin)


Best regards
« Last Edit: 07/09/2016 21:25:16 by akt1 »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20045 on: 09/09/2016 18:57:29 »
Yahoo! general audience publication article about POIS from 2015:

"The Crazy Reason This Man Never Wants To Orgasm"
By Amy Rushlow
https://www.yahoo.com/beauty/the-crazy-reason-this-man-never-wants-to-orgasm-110191674787.html


"This is not something we would wish on our worst enemy." (Photo: Getty Images)

THIS ARTICLE MENTIONS BOTH POIS FORUMS! :)
demo

« Last Edit: 09/09/2016 19:34:23 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20046 on: 09/09/2016 19:27:52 »
<former Mod visiting periodically>


HI acronym [see Acronym's question re NORD's POIS study on previous page]

•The 4th & final report will be out mid-September.

•No fMRI or tVNS study info has been released yet. Probably will not until final publication.



On Aug 29, 2016, at 7:10 AM, Jacqueline at NORD wrote:

Hi Demo,

[The Final POIS Study Public Report #4 -- officially due on September the] 18th is right around the corner so I'll be following up with the PI [Dr Komisaruk] this week to ensure he has the relevant paperwork etc., to submit it, and once passed to MAC for approval get to you ASAP for sharing.

I hope all is well with you.

Kind regards,
Jacqui
NORD


« Last Edit: 09/09/2016 19:45:22 by demografx »

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Offline akt1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20047 on: 11/09/2016 08:55:10 »
Update

Had a wet dream and got pois (could not sleep, it starts to "creep" in My body).
Took whey and niacin .. And Then i was ok.. Which os a breakthrough for me since whey and niacin
Seems to kill pois -after o-. Never Been able to get rid of it after o before.
I take whey everyday and have experienced a better general well being.
And if i combine niacin and whey daily i almost feel too good.. But maybe
Thats how i should feel - getting enough serotonin?

Have a Nice day
Akt1

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Offline FedUpWithThis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20048 on: 27/09/2016 21:24:16 »
Hi all, I've had brain fog for a lot of years constantly now. I thought that it would jus be exhaustion because of exercising and then masturbating, but none of my friends had the same symptoms. I've been searching all over the net for brain fog and what causes it, tried to take fish oil as a supplement but I have found out what is the cause of it, although I did suspect it would come from masturbating.

I have found out about POIS a few months ago so I tried see how directly related is masturbation to my extreme exhaustion. Turned up, it happens about 90% percent of the time I get at least one symptom the day after (on the same day, I get bad at socializing and my sight gets slown down).

I have a question, because the matter got worse this month. I used to get brain fog, reduced perception (sight, hearing), very slow reaction time, feeling like I am detached, unable to socialize and a lot of times extreme exhaustion ehich would drag on for a few days up to a week.

Now, I get higher temperature along with the other symptoms (37°C +) and I feel like sh1t (sorry for this), everything hurts me so much, just like if I had a flu and I barely sleep. Oh and I get diarrhea for two days as well. I've had "this" three times in one month, so it's hardly a flu. It's correlated to masturbation, and the symptoms increase with the intensity of orgasm.

I want to know, can POIS give those symptoms? Or am I just unlucky and caught a cold three times in a row?

I am 23 years old now, and had a brain fog for at least ten years (there were a few days in a year that I would feel great during high school and college). I tried abstinence, but sometimes I get to a point where I can't hold it anymore, even though I know how crappy I will feel after... Also there's are wet dreams which I can't help.

I exercise 4 times a week, calisthenics, but I feel like limited because of this.

I am very sad and depressed most of the time because of constant exhaustion and brain foggyness. There are only a few days each year that I feel on point, motivated and energetic... It's killing me knowing how I can't reach my potential. I am afraid of work now.
 
« Last Edit: 27/09/2016 21:32:47 by FedUpWithThis »

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Offline Titus1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #20049 on: 28/09/2016 11:01:53 »
Hello,

its my first post here.

Does actually somebody know what causes POIS??

I want to give all sufferers an advice! Try NAET Dr. Namudripad Allergy Elimination Technique. It works!! You will not have any problems after ejaculation with this therapie.

Never give up!

Kind regards!