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MRI OF THE BRAINScheduled for 12/26! I owe thanks to this forum for seeing a top endocrinologist. Why? Before this forum, I had no idea what those guys do for a living! Who knows if it's headed towards a cure. But I'm more hopeful now than any of the last 30 years! Thanks, guys/gal!
Do you remember exactly what molecule of testosterone you were taking ?(Some are safer for the liver)
Demografx, maybe you could ask dr Waldinger what he thinks about cortisol and Pois, next time you will send email to him. But don't send a new one just for this. You are the link beween him and this forum it's very very important to keep this link and don't boring him. Even my symptoms are not as severe as dr Waldinger described...
Possible anti-inflamation diet : Salmon(omega3), Wallnuts(omega3,maybe melatonin), Onions, bluberries(antocyanins), sweet potatoes, spinach, garlic, pineapple (bromelain), ginger, curcumin, apples(flavonoïds), cherries, olive oil, magnesium, vitamin C and K, green tea (without caffeine i suppose )
On the topic of anti-inflammatories, fenugreek has been documented as having anti-inflammatory properties. For example, see here: http://books.google.com/books?id=WJocdLd68sUC&pg=PA299&lpg=PA299&dq=fenugreek+inflammatory&source=web&ots=66s8NQuCpC&sig=Zi9b1RjKd4JIuIiwMdgKbSJqsM8&hl=en&sa=X&oi=book_result&resnum=1&ct=result#PPA299,M1 [Links inactive - To make links active and clickable, login or click here to register]Thus, at least two of the possibly effective POIS-combatting suggestions (garlic and fenugreek) are known for anti-inflammatory properties. So this could be a direction to pursue further.
Mysterious fenugreek But it works for 4/5 of us !
http://books.google.com/books?id=WJocdLd68sUC&pg=PA299&lpg=PA299&dq=fenugreek+inflammatory&source=web&ots=66s8NQuCpC&sig=Zi9b1RjKd4JIuIiwMdgKbSJqsM8&hl=en&sa=X&oi=book_result&resnum=1&ct=result#PPA299,M1 [Links inactive - To make links active and clickable, login or click here to register]says that the dosage range for the clinical studies was 50-100 grams of fenugreek seed per day. The Solgar capsules are 520 mg, so even if you take two per day, that is only 1 gram per day, compared to 50-100 grams! I'm not saying that we POIS folk should necessarily be taking that much, but it definitely seems like a big difference.
I added it; thanks Girlwind.
I was wondering if others out there have their sleep cycle/s interrupted during the 2 to 4 days of discomfort? If so, how so?
Martin, I found the bottle. Each mL contains Testosterone Cypionate Injection 200 mg.The testosterone did cure my POIS! Alas, a GIANT placebo effect: the first and only injection "worked". But my libido was low, so I continued anyway.Testosterone-replenished, having just come out from an extended depression which also left me with ED, my libido went from zero/maybe-minus to more-than-adequate. To the point of being attracted indiscriminately to many things that moved in my line of vision 
Quote from: demografx on 19/12/2008 16:18:10...my libido went from zero/maybe-minus to more-than-adequate. To the point of being attracted indiscriminately to many things that moved in my line of vision to many things!! 
...my libido went from zero/maybe-minus to more-than-adequate. To the point of being attracted indiscriminately to many things that moved in my line of vision 
Remember, it is the accidental discovery that often seems to lead the way for cures.
You case is very interesting because you are the opposite of some guys (Counterpoints and the "Relora testers" for example ) o brain fog but flu-like symptoms. I consider aches, back pain, sweats and chills are flu-like symptoms. You can see in the database cases like this.Sometimes they write : "i have knees pain " , " i have back pain " but they don't have brain fog. So i suppose adrenals are ok for them. Or at least steroids/cortisol ratio. I think for all cases for you, if you fight supposed inflammation after orgasm, your condition might be better.
...they don't have brain fog. So i suppose adrenals are ok for them.
I think for all cases for you, if you fight supposed inflammation after orgasm, your condition might be better.
What's the difference between 'brain fog' and 'feeling out of it'? Maybe the grumpy symptoms, etc., were unrelated to POIS?
Maybe Relora could help you too.
In the last couple months, my POIS has become rather unusual. After one orgasm, I commonly get all of the mental symptoms -- brain fog, social anxiety, etc. Sometimes a subsequent orgasm can alleviate these symptoms. HOWEVER, the relief only lasts for a few hours up to a day. Then I get this symptom of severe distress and anxiety, making it almost impossible to concentrate and develop my thoughts. This distress does not improve with time. Rather, it is worst in the morning until early afternoon, and becomes almost non-existent in the evening. It then gets worse again in the morning, and this cycle repeats.I'm thinking this might have something to do with cortisol: cortisol is usually highest in the morning, and decreases steadily until you go to bed. If there are any other ideas, though, I'd be happy to hear them. Alcohol makes this symptom worse. For example, if I drink in the evening, I will also likely feel this 'distress' in the evening.
It seems to me that exhaustion, fatigue and the other common symptoms of POIS require an incredible energy expenditure. We get into this deficit, and it takes time to come out of it. Our bodies require rest and rebalancing of hormones, neurotransmitters etc. Our nervous system has to return to "normal". Do we burn calories faster than others and at an intensity that puts us into a fight or flight response even though this excitatory period is relatively short, and we are obviously not in fear. For one, I've often thought that I'm releasing adrenaline almost as if there is a "wiring" error and my hyper-excitatory state is mistaken for danger. How else to explain the exhaustion and associated physical conditions? Lately my thought process has taken me to consider adrenal exhaustion as a possible cause of my problems and a nervous system that needs to be seriously built up. I definitely believe that my overall predispostion to anxiety contributes to the intense excitatory state that precipitates POIS and that my body may just become too overloaded. I wish it weren't like this; HOWEVER, I'm hopeful we will find a variety of natural solutions to boost our immune system (for lack of a better term)or strengthen our nervous system and improve our lives. This forum is the best place to brain storm and share ideas no matter how crazy. Remember, it is the accidental discovery that often seems to lead the way for cures. My latest experiments will be with Valerian Root and Holy Basil extract, just to improve my sleep and reduce anxiety. I'll go from there.
Quote from: B_Jim on 20/12/2008 07:30:52I think for all cases for you, if you fight supposed inflammation after orgasm, your condition might be better. I wonder if some of the 12-hour non-steroidal anti-inflammatory preparations (NSAIDS) sold over-the-counter - like *Aleve® with Naproxen Sodium - would work on POIS?
I have noticed, in myself and a few others, various stages of depletion prior to orgasm according to my level of sexual activity.Anyone noticed that?
Happy holidays. Hi, everybody, thanks for everything. It's been very nice making new friends here! - Demo
The nefarious aspect of this illness, for me , is that about 1-1 ½ times out of 10 times I can be orgasmic with absolutely no consequences…
Happy holidays to ALL pois sufferers!
Double Thanks Demografx:For Your Holiday Wishesand for sharing your lab test processes--I hope your efforts lead to some insight into hormone reactions with respect to POIS, and whether there is a sequence of biochemical events that may shed light on how our symptoms manifest themselves. Also, I assume that some of us may just have a genetic predispositon to this "illness". But this certainly does not preclude finding ways to diminish or "cure" this ailment. Thank your for this Forum. It is very therapeutic in itself.