Post Orgasmic Illness Syndrome (POIS)

  • 20071 Replies
  • 6553148 Views

0 Members and 12 Guests are viewing this topic.

*

Offline GoingCrazy

  • Hero Member
  • *****
  • 554
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5200 on: 07/08/2009 03:00:56 »
I used Ventolin for asthma in my teens.

A common denominator I see is that all of us were chronic/addicted to masterbating during early teens.

Oh yes... chronically addicted can't even describe it   [^]

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5201 on: 07/08/2009 03:02:47 »

GC, prolactin didn't seem to have any effect on my POIS. I was panicked about the 300%-higher-than-normal count, but the endo didn't seem concerned with the hyperprolactinemia.

Testosterone has been very effective for my POIS. But it also jumpstarted my libido. To achieve celibacy in this state, I would have to be pronounced a saint. Officially. [:)]

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5202 on: 07/08/2009 03:13:29 »

john13, and sclover49, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS forum resources which may be helpful to you:

Our new POIS Information Website is here:
http://sites.google.com/site/poiswebsite/

Please see "B_Jim"'s POIS Forum Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:
http://www.youtube.com/watch?v=UWBxAUC9k1g

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

If you want a copy (PDF), send me a Private Message with your regular email address and I'll send you back the PDF.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show the medical world - which often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community. This can help fight the immediate reaction of some: IT'S NOT "ALL IN OUR HEADS"!

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum for over 2 years, which has attracted over 100 POIS sufferers worldwide who have posted here, plus more than 350,000 page visits. Not bad for a rare malady!

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5203 on: 07/08/2009 03:16:18 »
john13, and sclover49, this post might help you find information about POIS that we have already discussed, by tailoring a Google search to this POIS forum:


SEARCH POIS FORUM WITH GOOGLE

We have an overwhelming amount of data: over 2 years' worth of posts from 150+ Forum members, and an additional 150 POIS sufferers found on the Internet, but not on this forum.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]site:http://www.thenakedscientists.com/

for example, I tried
demografx site:http://www.thenakedscientists.com/

and 1,000+ results came up for "demografx" within POIS Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5204 on: 07/08/2009 03:31:39 »

Martin, or anyone else that has experience with this, is there anything we can do about search engine optimization (SEO) for our new Information Website? http://sites.google.com/site/poiswebsite/

Can we, like the Naked Science Forum, put anything into the site code that helps people (POIS sufferers) find this new website easier? Such as keywords for the spiders...fatigue after orgasm, postorgasm anxiety, etc.?

Or, since this site program we're using is created by Google itself, maybe we don't have to worry about that?


*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5205 on: 07/08/2009 03:36:17 »

Celibacy

I hope no one takes my celibacy remarks/humor as anti-celibacy. I have respect for people who can. I'm just not one of them.

And I have decades' experience trying.
« Last Edit: 07/08/2009 03:37:49 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5206 on: 07/08/2009 04:34:05 »

From the Genetic and Rare Diseases (GARD) Information Center, August 5, 2009 - - Any thoughts, anyone?

Dear [Demo],

The Office of Rare Diseases Research (ORDR) recently forwarded your request regarding post orgasmic illness syndrome to the Genetic and Rare Diseases Information Center (GARD). GARD is a free information service directed by the ORDR and the National Human Genome Research Institute. In your e-mail you requested assistance in finding funds and researchers to study post orgasmic illness syndrome. You stressed that this is an important and under researched condition. You specifically requested the name of an association or person who would has the resources to research this condition.

While we are not able to provide the name of a specific organization or individual able to research post orgasmic illness syndrome, we have identified information resources that you might find helpful. If any of the links we have provided do not work, please copy and paste the entire address into your browser. If you have other technical difficulties with this e-mail, please contact GARDinfo@nih.gov or 888-205-2311 for technical assistance.

How can I learn about funding opportunities at the National Institute of Health?
The Office of Rare Diseases Research is part of the Office of the Director of NIH and not one of 27 distinct institutes and centers that make up the National Institutes of Health (NIH) and who have granting authority.  NIH is the principal health research agency of the Federal Government. At the NIH, the Office of Extramural Research (OER) serves as the common focal point for policies and guidelines for extramural research grants administration at the NIH. You can learn about NIH research and funding opportunities through this office. You can visit the OER web site at the link below.
http://grants2.nih.gov/grants/intro2oer.htm   

In addition, you can find a list of resources regarding research opportunities throughout the National Institutes of Health, at other federal agencies, and outside the Federal government with a focus on rare diseases at the following link.
http://www.rarediseases.info.nih.gov/Resources/Research_Resources.aspx

How can I find researchers who are interested in researching post orgasmic illness syndrome?
From your e-mail it seem as though you may have already started researching the literature for information on post orgasmic illness syndrome. This is a great way to identify researchers who may have an interest in studying this syndrome, as well as to determine what (if any) research has been undertaken in the past. In particular, you may wish to mine the CRISP and PubMed databases. CRISP (Computer Retrieval of Information on Scientific Projects) is a searchable database of federally funded biomedical research projects conducted at universities, hospitals, and other research institutions. To read about studies in CRISP, click on the link below. In the 'enter search terms' box, enter the search term(s) of your choice and click the 'and' button below the box. Then click 'Submit Query.'
http://crisp.cit.nih.gov/crisp/crisp_query.generate_screen   

PubMed is a searchable database of medical literature. Some articles are available as a complete document, while information on other studies is available as a summary abstract. To obtain the full article, contact a medical/university library (or your local library for interlibrary loan), or order it online using the following link. 
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed

The National Library of Medicine (NLM) Web site has a page for locating libraries in your area that can provide direct access to journals (print or online) or where you can get articles through interlibrary loan and Loansome Doc (an NLM document-ordering service). You can access this page at the following link.
http://nnlm.gov/members/

Additionally, we have listed below some umbrella organizations the first of which provides research grants. The second organization may not have funds for research, but they may be able to help you find interested researchers. We recommend contacting the organizations directly to learn more about research opportunities and interests:

American Urologic Disease Foundation
1000 Corporate Boulevard
Suite 410
Linthicum, MD 21090
Toll free: 1–800–828–7866
Phone: 410–689–3990
Email: aua@auanet.org
Web site: http://www.auafoundation.org/
Grants: http://www.auafoundation.org/researchpage.asp?toggle=research6&WT.cg_s=Professional

American Association for Marriage and Family Therapy
112 South Alfred Street
Alexandria, VA 22314-3061
Phone: (703) 838-9808
Fax: (703) 838-9805
Web site: http://www.aamft.org/

When trying to increase research interest in an emerging condition among the scientific community, it can be helpful to speak as an advocacy organization with a strong, unified voice. You may want to consider working with individuals or groups who share your situation, which might strengthen your voice. The following organizations have helped many advocacy groups get started, and have a wealth of information and knowledge to share about the process of raising funds and finding researchers with a passion to study your disease.

The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders.

National Organization for Rare Disorders (NORD)
55 Kenosia Avenue
PO Box 1968
Danbury, CT 06813-1968
Toll-free: 1-800-999-6673 (voicemail only)
Telephone: 203-744-0100
TDD: 203-797-9590
Fax: 203-798-2291
E-mail: orphan@rarediseases.org
Web site: http://www.rarediseases.org/

The Genetic Alliance is an international coalition comprised of more than 600 advocacy, research and health care organizations representing millions of individuals with genetic conditions. As a broad-based coalition of key stakeholders, the Alliance builds partnerships to promote healthy lives for all those living with genetic conditions. While post orgasmic illness syndrome may not be considered genetic at this time, many of the Genetic Alliance's resources are very relevant to goals that you've expressed. The Alliance maintains a forum where advocacy groups can mentor and learn from one another. To learn about the Genetic Alliance, visit the following link:
http://www.geneticalliance.org/

The Alliance's contact information is as follows:

Genetic Alliance
4301 Connecticut Avenue, NW
Suite 404
Washington, DC  20008
Phone: 202-966-5557
Fax: 202-966-8553
E-mail: info@geneticalliance.org
Web site: http://www.geneticalliance.org

We hope that these links give you a good starting point in your research. We suggest that you regularly revisit the Web sites for new information that may become available in the future. If you have any other concerns, please contact us again.

Sincerely,

Sarah Church
Information Specialist

 

The Genetic and Rare Diseases Information Center was established by the National Human Genome Research Institute and the Office of Rare Diseases at the National Institutes of Health to provide responses to public information requests. Information Specialists are available Monday through Friday, 12:00 p.m. to 6:00 p.m. Eastern time (excluding Federal holidays), to respond to questions about genetic and rare diseases.

 

Telephone:  888-205-2311

TTY:        888-205-3223

Email:      GARDinfo@nih.gov

Fax:        202-966-5689

Mail:       PO Box 8126

            Gaithersburg, MD 20898-8126

 

Important Disclaimer:

The materials provided are for informational or educational purposes only and are not intended as a substitute for professional medical care, advice, diagnosis, or treatment. This material does not represent an endorsement of any specific tests or products by the National Human Genome Research Institute or the Office of Rare Diseases at the National Institutes of Health. We cannot guarantee the accuracy, completeness, timeliness, or usefulness of the opinions, advice, services, or other information. Moreover, we strongly recommend that individuals seek the advice of a health care provider with any questions regarding medical care.
« Last Edit: 07/08/2009 06:20:38 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5207 on: 07/08/2009 04:58:39 »

A common denominator I see is that all of us were chronic/addicted to masterbating during early teens.


Oh yes... chronically addicted can't even describe it   [^]


Over masturbation: it's not clear what that means exactly. Especially in teen years. Here are some thoughts:
http://www.healthcaremagic.com/articles/Over-masturbation/7184

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5208 on: 07/08/2009 05:16:33 »

Martin, should we only fill in this form?


Pronobis, thanks for participating in the Email Form!

Just another reminder to everybody: your adding to this list just 1 or 2 emails can really help! It will only take you 5 minutes to find a good source or 2! We've already gotten impressive response from the few we sent!!

========================================================================

Once again, here's where you go to add an organization to our Email List:
http://pois.vndv.com

===============================================================

And don't worry about the letter/email to these organizations, I'll take care of that, or another volunteer, and we'll use Counterpoints' template from WHO and NORD and GARD as the letter. Just think of an organization who would be a good candidate to help the cause.
« Last Edit: 07/08/2009 06:14:02 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5209 on: 07/08/2009 05:21:46 »

Great job on the website!


Thank you, Dean, from Mat, me, and all the contributors!
« Last Edit: 07/08/2009 06:15:15 by demografx »

*

Offline Counterpoints

  • Hero Member
  • *****
  • 592
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5210 on: 08/08/2009 01:06:38 »
POIS an ADDICTION?

The more I think about POIS, the more I am certain it is like having a very intense addiction.

After three/four days of abstinence, I get a headache, I feel less fluent, and much less at ease.  Life generally just seems agitating.  These are classic signs of needing a "fix".  Most people would feel like this to some extent after abstinence, but not nearly with the same intensity, especially after such a short period of time.

Then, when my symptoms are alleviated by subsequent ejac., it seems that sometimes it feels as though I am "coming down" off of something, before I completely return to normal.
« Last Edit: 08/08/2009 01:19:38 by Counterpoints »

*

Offline Defsync

  • Sr. Member
  • ****
  • 161
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5211 on: 08/08/2009 02:18:30 »
Since oxytocin and vasopressin are released in great quantities during orgasm, I figured maybe an antagonist of them both might help with POIS. I found one called Atosiban, with a fairly detailed descript of physiological affects it can ahve on the body. Apparently Oxytocin is released in smaller quantities when heavier meals are eaten, as it is involved in gastric emptying (the rate at which your food leaves the stomach for the small intestines.) This study:

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1434749

seemed to find no serious side effects with men taking Atosiban. A couple things I would like to test:

1) taking Desmopressin (the synthetic form of Vasopressin), to see if POIS symptoms result. It can be ordered here:

 http://www.biogenesis-antiaging.com/product_info.php?products_id=47&

2) taking Oxytocin, for the same reason. Can be ordered here >>>edited:***APPARENTLY THIS CAN BE VERY DANGEROUS, ESPECIALLY WITH MEDS LIKE VIAGRA***
I would like to note that at one time in 2001 I bought a nasal spray of Oxytocin from switzerland and it had no affect when I used it.

3) take Atosiban to see if it stops POIS symptoms. However this may be hard to come buy without a doctors help, and I'm not even sure if its available in non-intravenous form.

« Last Edit: 08/08/2009 02:41:33 by Defsync »

*

Offline Defsync

  • Sr. Member
  • ****
  • 161
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5212 on: 08/08/2009 02:31:46 »
Hmm found an article that mentions a lot more biochems that are involved in the vas deferens (which has to do with the transport of sperm, and thus involved in orgasm), including adenosine, neuropeptide Y, somatostatin, calcitonin gene-related peptide, substance P, galanin, nitric oxide synthase, and vasoactive intestinal peptide.

Here's a link to the article:

http://www.biolreprod.org/cgi/content/full/77/3/416

An exerpt:

"OT and VP are now firmly placed among a list of physiological agents that are documented to increase anion secretion across epithelial cells derived from the vas deferens. Norepinephrine, vasoactive intestinal peptide (VIP), histamine, adenosine, and VP were reported previously to stimulate anion secretion across 1°PVD [30] and PVD9902 cells [28], and adenosine was shown to stimulate anion secretion by 1°HVD cells [43]. A clearer picture of anion secretion regulation emerges as these observations are combined. Norepinephrine, VIP, VP, and OT exhibit activity exclusively from the basolateral aspect of the cells, whereas adenosine effects on 1°HVD are observed only with apical exposure [43]. Adrenergic agonists, adenosine and VP increase adenylyl cyclase activity to promote cAMP generation, whereas OT (and VP likely acting at OXTR) appears to act via a PKC-dependent mechanism. These results suggest that vas deferens epithelial cells integrate signals from a variety of sources to produce a fine-tuned response in the rate and composition of secretions. Submucosal neurons in pig and human vas deferens reportedly contain noradrenalin, VIP, neuropeptide Y, somatostatin, calcitonin gene-related peptide, substance P, galanin, and nitric oxide synthase [52–56]. There may, however, be some species to species differences in OXTR-mediated function, as strong OXTR immunoreactivity has been reported for epithelial cells lining the vas deferens of rams [57] while little OXTR immunoreactivity was observed in marmoset vas deferens [36]. There is clearly a response to OT and VP by cells derived from both the human and pig vas deferens when grown in culture. The source of either VP or OT that would affect vas deferens function in vivo is uncertain. Some reports have suggested that OT is synthesized in the testis [36] and that sexual arousal or orgasm may be associated with elevated serum OT levels [37–39, 47], presumably from the pituitary. Likewise, substantial amounts of VP are also present in testis [38], which suggests local synthesis, and serum levels of VP increase prior to ejaculation [39]. Regardless of source, the present results show that concentrations of OT and VP at or near the physiological range can modify the activity of epithelial cells derived from the vas deferens that, in vivo, would be expected to modify the volume and composition of the luminal environment.

Contributions of the vas deferens to male fertility are poorly defined. Mammalian sperm can neither swim nor fertilize an egg when they leave the testis, but acquire these abilities as they traverse the epididymis [1, 2]. The efferent ducts concentrate sperm by reducing fluid volume by ~96% while maintaining constant Na+ and Cl– concentrations [3, 4]. Approximately 50% of the remaining fluid is absorbed in the epididymes [3]. Luminal pH is reportedly reduced from neutral in the rete testis to ~6.5 in the caput epididymis, a pH that maintains sperm in a quiescent state during storage [58]. HCO3– exposure activates sperm by directly stimulating soluble adenylyl cyclase [11, 12] and by the activation of Ca2+ channels resulting in hypermotility [10]. It was proposed previously that adrenergic stimuli during the pre-ejaculatory arousal period would be expected induce HCO3– secretion that would raise luminal pH and initiate the activation process in sperm [30]. Current results suggest that OT and/or VP may have a similar effect. The serum concentration of both hormones increases during sexual arousal [39] and the results show that direct effects on epithelial anion secretion can occur near the range of concentrations reported in serum. Taken together, these observations strongly suggest that vas deferens epithelium is acutely modulated by OT and VP, in addition to locally released neurotransmitters."
« Last Edit: 08/08/2009 03:32:32 by Defsync »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5213 on: 08/08/2009 02:38:39 »

I posted this about 10 months ago:

From my pharmacology-attorney friend:

OXYTOCIN

"Oxytocin is a prescription drug and very dangerous if used incorrectly. It is used primarily in obstetrics to induce labor and can precipitate abortion. DO NOT TAKE THIS DRUG.  It can also cause a precipitous drop in blood pressure. Deadly combo if used with Viagra."

At the time he wrote this, he might have been referring primarily to me, because of my high blood pressure (successfully med-controlled) and use of Levitra. Nevertheless, I thought it worth posting, especially since the first sentence warning may apply to many people, not just those with my particular medical history.
« Last Edit: 08/08/2009 02:46:25 by demografx »

*

Offline Defsync

  • Sr. Member
  • ****
  • 161
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5214 on: 08/08/2009 02:41:58 »

I posted this about 10 months ago:

From my pharmacology-attorney friend:

OXYTOCIN

"Oxytocin is a prescription drug and very dangerous if used incorrectly. It is used primarily in obstetrics to induce labor and can precipitate abortion. DO NOT TAKE THIS DRUG.  It can also cause a precipitous drop in blood pressure. Deadly combo if used with Viagra."


thanks, I edited my previous post, good lookin out =)

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5215 on: 08/08/2009 02:48:18 »

Defsync, to clarify, I just added a paragraph to that post, in italics.

*

Offline GoingCrazy

  • Hero Member
  • *****
  • 554
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5216 on: 08/08/2009 04:12:58 »
POIS an ADDICTION?

The more I think about POIS, the more I am certain it is like having a very intense addiction.

After three/four days of abstinence, I get a headache, I feel less fluent, and much less at ease.  Life generally just seems agitating.  These are classic signs of needing a "fix".  Most people would feel like this to some extent after abstinence, but not nearly with the same intensity, especially after such a short period of time.

Then, when my symptoms are alleviated by subsequent ejac., it seems that sometimes it feels as though I am "coming down" off of something, before I completely return to normal.

That's one of the theories I still consider too.  Celibacy always benefits me.  When I was abstinent for 4 weeks and took candida treatment I had no POIS afterwards until about my 5th orgasm.  So I believe its either the candida treatment that's working, or the celibacy.  Some people say POIS is worse after long bouts of abstinence, I think we just get used to what non-POIS feels like than when we get into POIS we feel very bad, but still in POIS like we never took a bout of abstinence... if you can follow me  [:-\]
« Last Edit: 08/08/2009 17:15:15 by goingcrazy »

*

Offline martin88

  • Sr. Member
  • ****
  • 453
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5217 on: 08/08/2009 05:03:58 »
according to this, vasopressin is released more before orgasm (?). Ok for oxytocin.
http://books.google.com/books?id=Mp3ZKfleBe8C&pg=PA107&lpg=PA107&dq=vasopressin+orgasm&source=bl&ots=t_t0kYFpms&sig=hzEtv9Yf-2EzdvzDEkq-HAqi9cY&hl=en&ei=N-R8Sq_DBqGBtwePzOHsAQ&sa=X&oi=book_result&ct=result&resnum=5#v=onepage&q=vasopressin%20orgasm&f=false

is there anything we can do about search engine optimization (SEO) for our new Information Website? http://sites.google.com/site/poiswebsite/
... keywords for the spiders...fatigue after orgasm, postorgasm anxiety, etc.?
you can submit your url to search engines (msn,yahoo etc)  I'd suggest to put only true (or at least referenced) information on this site before anything.

About the reply from GARD all we can do is to contact the emails they gave us and see what happens..
« Last Edit: 08/08/2009 05:05:47 by martin88 »

*

Offline Dean93

  • Full Member
  • ***
  • 84
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5218 on: 08/08/2009 05:25:22 »
Goingcrazy, was that your first period of celibacy? Longest?

*

Offline tazdas

  • First timers
  • *
  • 2
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5219 on: 08/08/2009 08:06:30 »
Guys I am first time here and I am 30...I have had POIS since my teens and I have done lots of research on this. POIS is very well knows in Chinese and south east asian Medicine for centuries. Modern medical science use to brush this issue under the rug saying that its all in the 'mind'.

I play lots of sports so I can really feel POIS when it happens

Here are my POIS symptoms that come and go and generally last for 2-3 days

Immediately triggers my mild Asthma (Not every time)
Immediately triggers my allergies i.e Hay fever symptoms (Not every time)
Lower back pains and knee pain..
Weakness in my knees/back
Makes my older lower body injury areas such as Hamstring, shin splints, knee (pettalor tendons) areas temporarily raw, weak and painful..
 
« Last Edit: 08/08/2009 21:52:06 by demografx »

*

Offline John21

  • Hero Member
  • *****
  • 518
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5220 on: 08/08/2009 11:04:54 »
tazdas,
Quote
After doing lots of research I found the supplements from this site 'http://www.actionlove.com/' to be really helpful and they relieved my symptoms specially the lower body pains/weakness. Not a very organized site but I found the some of his POIS explanations logical and understanding. 

I would suggest that you guys do your own research on this site and do a lot of reading and maybe try out the supplements..

I tried his suppliments once and it only helped to spend my money.

*

Offline martin88

  • Sr. Member
  • ****
  • 453
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5221 on: 08/08/2009 13:02:39 »
vasopressin is released more before orgasm (?).
I had the same question with a theory I posted on epinephrine. I can't know if epinephrine or vasopressin increase between 1 second before orgasm and just after. I don't have POIS if I stop just before orgasm..

It's possible that there is a sudden drop of vasopressin after orgasm causing POIS ??
« Last Edit: 08/08/2009 14:17:48 by martin88 »

*

Offline mellivora

  • Sr. Member
  • ****
  • 152
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5222 on: 08/08/2009 15:05:14 »
There's a LOT of info to digest on this forum. I'm still catching up! Congratulations to everyone who has alleviated their symptoms, it seems like there was a lot of progress for a few people earlier this year. It's inspiring.

Here's something that might be of interest to those nitric oxide theorists amongst you. (Demo and others have discussed this in relation to Levitra's effects and Chewbacca asked a long time ago if there was a natural source of nitric oxide). Beetroot juice is high in nitrate which may convert to nitric oxide in the body. The following artice hints at this in relation to athletic performance:
http://news.bbc.co.uk/1/hi/health/8186947.stm

« Last Edit: 08/08/2009 15:20:57 by mellivora »

*

Offline GoingCrazy

  • Hero Member
  • *****
  • 554
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5223 on: 08/08/2009 17:14:21 »
Goingcrazy, was that your first period of celibacy? Longest?

Definitely my longest for about 4 weeks.  But prior to that I would be off an on for a week, than a week 1/2, than a week of abstinence, etc.  Most times, not even reaching a week.
« Last Edit: 08/08/2009 17:16:16 by goingcrazy »

*

Offline Dean93

  • Full Member
  • ***
  • 84
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5224 on: 08/08/2009 18:13:54 »
Goingcrazy, was that your first period of celibacy? Longest?

Definitely my longest for about 4 weeks.  But prior to that I would be off an on for a week, than a week 1/2, than a week of abstinence, etc.  Most times, not even reaching a week.

How did you manage not to have any NE's?

I'd be celibate for as long as I had to if I could avoid those.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5225 on: 08/08/2009 21:39:56 »

After doing lots of research I found the supplements from this site 'http://www.actionlove.com/' to be really helpful and they relieved my symptoms specially the lower body pains/weakness...I would suggest that you guys do your own research on this site and do a lot of reading and maybe try out the supplements..
 

tazdas, I get concerned about any first-time poster coming here after 5,000 posts to this forum and recommending products, especially ones we've looked at and not very favorably (as John indicated). It's considered spam, and the poster is subject to banning, so I am deleting that reference. Here's a couple hundred Google results on actionlove.com you may want to read first from this forum. If you have comments about the previous posts, please let us know:
http://www.google.com/search?hl=en&q=actionlove.com+POIS+site%3Ahttp%3A%2F%2Fthenakedscientists.com&aq=f&oq=&aqi=

If you'd like to know more about us first, let me know and I'd be happy to start you off with some references about this forum and our website.
« Last Edit: 09/08/2009 05:57:09 by demografx »

*

Offline Defsync

  • Sr. Member
  • ****
  • 161
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5226 on: 09/08/2009 01:22:54 »
btw people, if you click the PRINT icon at the top or bottom of this thread, it displays the ENTIRE thread (every post) on one page in a general text format. I've been doing this periodically then saving it to my hard drive as backup/up-to-date reference.

*

Offline GoingCrazy

  • Hero Member
  • *****
  • 554
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5227 on: 09/08/2009 04:47:18 »
Goingcrazy, was that your first period of celibacy? Longest?

Definitely my longest for about 4 weeks.  But prior to that I would be off an on for a week, than a week 1/2, than a week of abstinence, etc.  Most times, not even reaching a week.

How did you manage not to have any NE's?

I'd be celibate for as long as I had to if I could avoid those.

         Well, I can only say I experienced an NE once during the 4 week period of abstinence, and that was possibly, not really sure I had it.  I don't take any measures to avoid it.  But the first one I had during abstinence led me feeling very calm afterwards, non-POIS like. 
         Say now if I had an NE I doubt it would lead me into POIS because I believe my orgasms now to have a say, 1/3 chance of causing POIS.  As I said I had about 5 orgasms and the last one spiraled me into POIS and bad moods, etc.

*

Offline Dean93

  • Full Member
  • ***
  • 84
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5228 on: 09/08/2009 05:34:24 »
Thanks Goingcrazy.

Was anyone here not breastfed as an infant? I wasn't.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5229 on: 09/08/2009 05:40:22 »
Disappointed, but also encouraged

Martin was the only forum member who responded to my request for feedback on GARD. I don't recall about NORD and the Email List for outreach, but my sense is that response is very, very light.

As GARD and NORD have both pointed out, the difference between success and failure for groups like us - in finding funding and researchers for curing POIS - is to become a strong advocacy group.

How do we do that?

However, I'm very strongly encouraged by the 3 forum members who have stepped forward and committed hard, cold cash towards researching our cure!

Very exciting news!




*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5230 on: 09/08/2009 05:46:45 »

btw people, if you click the PRINT icon at the top or bottom of this thread, it displays the ENTIRE thread (every post) on one page in a general text format. I've been doing this periodically then saving it to my hard drive as backup/up-to-date reference.


Thank you, Defsync. That is very useful info. I didn't realize it was so easy to backup this whole thread!

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5231 on: 09/08/2009 05:50:42 »

1) taking Desmopressin (the synthetic form of Vasopressin), to see if POIS symptoms result. It can be ordered here:


I've been toying with the idea of taking this for years for my nocturia, with my urologist's approval, but I've been afraid of the side effects.

*

Offline CertainlyPOIS

  • Hero Member
  • *****
  • 727
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5232 on: 09/08/2009 06:01:55 »
This adrenal fatigue seems very plausible. It kinda touches on everyone symptoms and things noticed about pois.
It connects immunity, fatigue, brain fog, sleep ( deep sleep and inability to sleep at night even though tired) It also explains why carbhydrate worsens symptoms and why lots of protein helps symptoms.
The adrenal might connect all our symptoms.
What do you guys think.

After my blood test result come where i tested 13 hormones i think i am going to do adrenal streess index.



*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5233 on: 09/08/2009 08:09:07 »

This adrenal fatigue seems very plausible. It kinda touches on everyone symptoms and things noticed about pois.
It connects immunity, fatigue, brain fog, sleep ( deep sleep and inability to sleep at night even though tired) It also explains why carbhydrate worsens symptoms and why lots of protein helps symptoms.
The adrenal might connect all our symptoms.
What do you guys think.

After my blood test result come where i tested 13 hormones i think i am going to do adrenal streess index.


POIS gives me carb cravings, then indulging the carbs helps. Especially lasagna.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5234 on: 09/08/2009 19:39:21 »

I think it is the opposite for most people. Does anyone else have POIS carbo-crave?

*

Offline Defsync

  • Sr. Member
  • ****
  • 161
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5235 on: 09/08/2009 20:53:51 »

I think it is the opposite for most people. Does anyone else have POIS carbo-crave?

only craving I get from POIS is for a week to pass by as quickly as possible =)

*

Offline CertainlyPOIS

  • Hero Member
  • *****
  • 727
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5236 on: 09/08/2009 21:58:02 »
During pois i get craving for anything but when i eat lots of carbs i feel the pain.

Bjim, why do you say the pancreas too.

*

Offline JonJen99

  • First timers
  • *
  • 5
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5237 on: 09/08/2009 22:02:19 »
Herbs and supplements I've tried

ZMA: (Zinc, Magnesium, b vitamin): made it worst (no longer take)

Ashwaghanda: helped a little at first but later caused difficulty sleeping (no longer take)

Rhodiola Rosea: slight increase in energy, but caused difficulty sleeping (no longer take)


Like another poster above me, I have actually had BETTER sleep with Rhodiola rosea. My experience is that if you take it no later than 5 PM or so, there's no issue even for the sensitive person. I can take it at 10 PM and go to sleep an hour later, with the most incredible dreams! The brand I take has no additives (it's called Mind Body & Spirit) while some of them have caffeine in them. That might be what bothered you! Try some of the better brands, the high end ones (that work) include Verde Botanica and the one I mentioned. Good luck!

*

Offline GoingCrazy

  • Hero Member
  • *****
  • 554
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5238 on: 10/08/2009 02:16:59 »

I think it is the opposite for most people. Does anyone else have POIS carbo-crave?

It's not like I crave carbs, it's just that I am hungry all the time.  When I eat carbs, especially pasta, I usually get really tired at least for an hour afterwards.

*

Offline POIS-SUFFERER

  • Sr. Member
  • ****
  • 133
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5239 on: 10/08/2009 02:35:19 »
Sclover49


--  For my personal experiences, I was in college all last year and I would say I got about 12 hours of sleep each night for half of a year.  What I didn't do was go to bed before 12.  My sleep hours would honestly be from 2 am to about 2 pm, because I took night classes.  I honestly feel better sleeping before 12, and waking up as the sun wakes me up.  I try not to "sleep in" as I did in college because it didn't help me.  But what I did not do in college was combine a lot of sleep with celibacy.

--  I think sleeping before 12 pm is the serotonin/dopamine/melatonin  <-- I really don't know but--- something with chemicals in your head.  In POIS I never get tired.  Out of POIS I can actually feel my body getting tired... Maybe a buildup of some kind of chemical depleted after orgasm?

--  As for being weaker than my friends... it all depends on who to compare it too.  I believe POIS has no affect on your size, but definitely your strength and ability to perform.  <-- POIS mental affects.  I experience about double the brain fog I normally do after a long workout for some reason.  I had that thought in my head too, I think it's more of a depressed POIS thing, thinking I am worse than others around me.

--  Even now with sleep I would have to say I wake up about 3-4 times each night, and I also sleep with a fan blowing in my face which helps me fall asleep, but maybe that's not such a good idea for deep sleep.

Does anybody experience a bad reaction after viewing porn, not after masturbating.. just viewing porn?  Maybe it is a guilt thing.

I have quit sexual stimulation "non-orgasmic" sex, masturbation and viewing porn...a complete laissez-faire "hands off" type of personality      [:P]



As I am learning from my Homeopath Dr. it seems my POIS could all be related to a burned out adrenals, your adrenals has a cycle in 4 phases.... it needs you to go to sleep by around 10PM! and wake around 8AM, this is its normal rythum, this is why you may feel this way..... If it is a burned out adrenal causing your issues, you will probably feel most alert and active in the later evening also! and have a hard time waking....

Also the sleepy with carbs she said was also related and I have that too! Not just sleepy but sever fatigue!

PS.

(I am not a DR, I am only relaying info)

*

Offline POIS-SUFFERER

  • Sr. Member
  • ****
  • 133
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5240 on: 10/08/2009 02:38:45 »

I think it is the opposite for most people. Does anyone else have POIS carbo-crave?

I usually take Ativan right now to make me feel better, and when it kicks in I just get the good old munchies! :-)

PS

*

Offline GoingCrazy

  • Hero Member
  • *****
  • 554
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5241 on: 10/08/2009 05:04:33 »
POIS-SUFFERER

Burnt out adrenals was at first what I thought it was also.  I always felt like coffee somehow caused all of this.  It is still a pretty good theory if you ask me.  When I used to drink coffee it used to prevent me from dreaming at night, hence no deep sleep.  The previous night I went to bed before 12 and felt kind of "POIS" in my dream, and then felt very calm in an instant afterwards.  Maybe some neurotransmitter release, but that rarely happens to me.  I think it was because I went to bed before 12.  Gave my body a full deep rest.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5242 on: 10/08/2009 06:08:47 »

I think it is the opposite for most people. Does anyone else have POIS carbo-crave?

only craving I get from POIS is for a week to pass by as quickly as possible =)


Haha! Best answer yet!

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5243 on: 10/08/2009 06:16:43 »


JonJen99, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS forum resources which may be helpful to you:

Our new POIS Information Website is here:
http://sites.google.com/site/poiswebsite/

Please see "B_Jim"'s POIS Forum Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:
http://www.youtube.com/watch?v=UWBxAUC9k1g

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

If you want a copy (PDF), send me a Private Message with your regular email address and I'll send you back the PDF.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show the medical world - which often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community. This can help fight the immediate reaction of some: IT'S NOT "ALL IN OUR HEADS"!

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum for over 2 years, which has attracted over 100 POIS sufferers worldwide who have posted here, plus more than 350,000 page visits. Not bad for a rare malady!

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5244 on: 10/08/2009 06:21:13 »

JonJen99, this post might help you find information about POIS that we have already discussed, by tailoring a Google search to this POIS forum:


SEARCH POIS FORUM WITH GOOGLE

We have an overwhelming amount of data: over 2 years' worth of posts from 150+ Forum members, and an additional 150 POIS sufferers found on the Internet, but not on this forum.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]site:http://www.thenakedscientists.com/

for example, I tried
demografx site:http://www.thenakedscientists.com/

and 1,000+ results came up for "demografx" within POIS Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

*

Offline JonJen99

  • First timers
  • *
  • 5
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5245 on: 10/08/2009 17:02:14 »
JonJen99 : Welcome, thanks for rodiola rosea.
Are you a Pois sufferer :) ?
Can you give more details ?

Jim, I've lurked here for some time. I don't feel comfortable discussing my condition, but yes -- I've had pois since college, and that was MANY years ago. I've had some relief from pharma, but mostly from herbs.

*

Offline lauracostis

  • Sr. Member
  • ****
  • 257
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5246 on: 10/08/2009 20:03:27 »
has anyone looked into "neurosteroids", they are converted in the brain from regular steroids such as testosterone, fsh, and lh, ect.  neurosteroids naturaly cause sedation and are synthesized now for the purposes of surgical sedation.  "17-Phenylandrostenol" - is an antagonist that blocks the effects of neuroactive steroids

*

Offline lauracostis

  • Sr. Member
  • ****
  • 257
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5247 on: 10/08/2009 23:33:28 »
anyone with medical background go to wickipedia and read about "neurosteroids" and then ("GABA a" receptors ).  neurosteroids that bind to "GABA a" receptors release cholride, causing hyperpolarization, which stops an action potential or signal from moving down the axons of a neuron.

*

Offline lauracostis

  • Sr. Member
  • ****
  • 257
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5248 on: 11/08/2009 00:01:59 »
on a similar note to posible problems with ions; a book i read about fibro myaglia, the doctor claimed that it was caused by a problem with sodium/potassium pumps in cells.  some how active transport of na/k in cells becomes inbalanced, causeing inproper difusion gradiant between inside and outside of cell.  the result would cause endless problems in the body of all kinds, responsible for the many signs and symtoms packaged together in the syndrom of fibro myalgia.  the easyist to detect were the cause of the painfull areas on the back that became chronically inflamed.  the theory being that the difusion imblanced caused the inside of the cell to become hypertonic, pulling in as much fluid as posible to equalize tonicity.  with active transport working improperly, compounds and ions continue to build in cell causeing more swelling fromm water entering cell from osmosis.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8197
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5249 on: 11/08/2009 05:24:01 »


has anyone looked into "neurosteroids"


lauracostis, I'm not sure how you're relating that to POIS? And also your last 2 posts...
« Last Edit: 11/08/2009 05:57:31 by demografx »