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After full ejaculation or orgasm a signal is sent from the testicles to the hypothalamus for the release of GnRH. The GnRH hormone travels from the hypothalamus to the pituitary and stimulates gonadotropin release. Gonadotropins travel to the testicles and stimulate testosterone production. This system is known as the HPG axis ( hypothalmic-pituitary-gonadal axis ).Maybe in POIS, after ejaculation, rather than the HPG axis, the HPA axis gets activated. The HPA axis ( hypothalmic-pituitary-adrenal axis ) is responsible for releasing stress hormones including cortisol. This would mean that the end result after ejaculation would be more stress rather than more testosterone.Research needs to be done as to why this axis crossover occurs.Do you see how the adrenals are downstream from the true source of the problem, which is the hypothalamus ?
Demografx feels much better with dopaminergic Levitra.
Hi guys, Thank you very much for replies, they mean a lot. Its reassuring to know there are people out there who understand. I had another nocturnal emission last night :/ but as you can see.. Im still here... I do not know if this has already been posted but i found this article:...sorry, you cannot view external links. To see them, please
REGISTER or LOGINparticularly go down to sex's hidden hangover
Demografx, I agree the symptoms are very unique. There is a huge lack of physical and mental energy. Severe depression is the most significant illness I experience. I wonder if this is true for others ?Demografx, you asked me above what the next step should be. I think a letter should be sent to the head of research endocrinology directed at several universities. Within the letter outline a discription of the illness and call it POIS. Make a reference to this forum with its URL.
My POIS symptoms are unique, different to when I have done lots of sport. Mine includeMental Fog, Can't concentrate or think logically, work things out or recall necessary things.Severe Depressiona little physical fatigue and headacheLarge pupilsActually to mention on that stretching thing i did find it harder to stretch in a pois cycle, and I used to do lots of hard stretching. I also have pretty bad OCDAnd guess what, i had another wet dream last night! and I have an A2 Module tomorrow! Doesn't it just make you glad to feel alive..
Quote from: rapidgaming on 11/05/2008 09:19:32I do not know if this has already been posted but i found this article: newbielink:http://www.reuniting.info/science/sex_and_addiction [nonactive]particularly go down to sex's hidden hangoverRAPIDGAMING,Very interesting article! I think it agrees with B_JIM's theories.
I do not know if this has already been posted but i found this article: newbielink:http://www.reuniting.info/science/sex_and_addiction [nonactive]particularly go down to sex's hidden hangover
So you were able to have an orgasm without ejaculation and you'd still have the POIS?I don't understand, because the link rapidgaming provided stated that with those techniques the dopamine-hangover is avoided...Or she uses another technique? Does anyone know?for others that don't know: Kegel-excercises are to strengthen the PC-muscle
...Now Apomorphine HCl, a dopamine agonist that stimulates erection, is being approved, and is already for sale in Europe......A dopamine agonist drug, therefore, produces effects similar to dopamine in the brain...Maybe is Levitra acting as dopamine agonist?...sorry, you cannot view external links. To see them, please
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Demografx, I will send you a beginning of letter next week.
If a research team does decide to look into this condition, I wonder how many of you will be willing to travel and participate ??
I'd be willing to participate, HANDS DOWN.
demografxI think the problem of this research will be that everybody would like to stay anonymous. Even if this eventful discovery of the solution to POIS is groundbreaking, nobody would like to be named as subjects with POIS....Therefor the endocrinologists should treat all test subjects and control subjects as anonymous.
In fact, the list of Chronic Fatigue Syndrome symptoms at this site:...sorry, you cannot view external links. To see them, please
REGISTER or LOGINalmost make it seem as though POIS could be a 'short-term' or 'specific-occasion-induced' form of CFS.
It's known as a PDE5 inhibitor--does anybody know what that means?
I was just wondering if anybody would be willing to meet other people with this condition in second life?
What do you mean by second life?
Hi fellow POIS sufferersDo you folks find that POIS seriously affects every aspect of your life everyday ?.I find this a very powerful illness which affects me everyday. This is because the mental symptoms linger for so long after an orgasm.
It's been a while since i last posted anything in this thread.I was just wondering if anybody would be willing to meet other people with this condition in second life?I would like to create such a place but I have no idea wether people would come.