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i believe there is fundamentally nothing wrong with us and drugs are just a quick way out.
CCconfucius, if you (and Danny_Boy) wish, maybe you could speak with Peter Weiss, he's the original Czech researcher I spoke with who strongly recommended testosterone to me for POIS. He was highly recommended by a foremost sex researcher at Johns Hopkins University. If you want his email address, please PM me.
Quote from: Looking_for_answer on 16/10/2009 07:07:20i believe there is fundamentally nothing wrong with us and drugs are just a quick way out. Very interesting point of view, not sure I agree. Anyone else have a thought about that?
Dopamine is a good possibility to explain some symptoms (of course mental fatigue , repeted yawns when dopamine is depleted; headaches, shortness of breath, and diarrhea (activation of D-1 receptor on intestinal tract) after the supposed "dopammine rush" by orgasm).But it is difficult to explain some symptoms like fever hours following orgasm. Medicine documents about cocaine users(extreme dopamine stimulant) talk about fever and muscles tremors. But when dopamine level is very high (overdose). Something is wrong. It is difficult to explain why the cognitive symptoms appear after 24 hours. Nobody can explain symptoms because there are different steps (tyrosine-dopa-dopamine-noradrenaline-adrenaline) in different body's areas. It's difficult to explain some digestive symptoms and inflammation symptoms (pains in knees, joint... ). I really think immune systme is involved. There is an excellent link between dopamine,immun syst and inflammation here.---It seems on my case only white sugar(saccharose) have negative effect on Pois. I will try again. Ii seems I don't have the same negative effects with other high glycemic carbohydrates as rice, bread and potatoes. Studies on rats show effect of sugar on dopamine. But nobody knows if the release of dopamine is caused by pleasure to eat sugar or if there is a specific mechanism between saccharose and dopamine. And what about other sugars ? (starch, fructose, lactose...).
I genuinely think that we all suffer from a hormonal imbalance caused by orgasm
my hangover is very similar to pois
im a strong believer in the power of the body. i mean, give it the nutrients it needs and it will solve its problems way before you figure it out. So in my case I'm tempted to look at everything that the body needs to produce sperm, and then see if i might be lacking some of it. Since sperm is partly made of the brain fluid, it could make sense that ejaculating would induce cognitive skills loss for a few days (time to replenish to minimal level). Chinese medicine has apparently held a similar view for a very long time. Not to discredit western medecine, but i have talked to a lot of doctors with nice diplomas and zero common sense. i believe there is fundamentally nothing wrong with us and drugs are just a quick way out. im considering starting taking zinc at 10mg/kg/day for a few months, even if it apparently gives nausea. anyone tried this or had an opinion about what other nutrients is required for sperm production?
Don't most Asians lack the enzyme to convert alcohol into a non-toxic substance "asian flush" interesting because my hangover is very similar to pois.... also i know it sounds weird but my pois has a little to do with circulation cuz standing on my head after orgasm takes the depersonalization away...i know it sounds weird but very easy to test out so if it works for anybody else please tell me so i don't feel crazy:)
My POIS treatmentLately, I've been able to maintain almost 100% POIS-free episodes (increased testosterone and increased adderall). Can't really explain it (the near-100%). Maybe the treatment is catching up and is in effect a "wholesale cure"!Today, when Day Zero symptoms started creeping up, I forced myself out into the sunshine...and it worked! (My natural tendency on Day Zero is to maximize physical/mental passivity). Simplistic? You bet! 
Quote from: hurray on 16/10/2009 23:36:41I genuinely think that we all suffer from a hormonal imbalance caused by orgasmHurray, I have always thought that was a "sacred cow" of POIS as well, but how would you explain the fact that several members here have come up with normal readings hormonally?
B_Jim, Hurray, Demo,I buy the idea that at least one form of POIS is caused hormonally. Here is what could be going on. Simplistically: too much adrenaline is produced and has difficulty converting back to dopamine. Dopamine runs low, producing symptoms, and the excess adrenaline produces symptoms. Demo, Have you ever tried taking tyrosine?
Demo, Have you ever tried taking tyrosine?
Hurray, I now understand better your position on hormones I agree.Just curious, hurray, why you stress hormones over, say, neurotransmitters? (I do, too, but I can't explain why).
Hormones vs NeurotransmittersSimilarities:Both H and NT are packaged in vesiclesBoth are expelled from cell through process of exocytosisBoth bind with specific receptorsBoth depolarize target membraneDifferences:Hormones1) secreted by neurons and endocrine cells2) secreted into bloodstream3) travel nanometers to meters4) long latency of action5) no voluntary controlNeurotransmitters1) secreted by neurons2) secreted into synaptic cleft3) travel 20-30 nanometers4) action is generally immediate5) some voluntary control
has anyone done ECG, EEG, CT, MRI, blood pressure, glycemia, blood count, temperature, hormones right after orgasm?
Quote from: ajs on 17/10/2009 02:39:38my hangover is very similar to poisMe too. I stopped drinking 16 years ago. Jet lag and exercise also cause strange body/mind reactions.
has anyone done ECG, EEG, CT, MRI, blood pressure, glycemia, blood count, temperature, hormones right after orgasm?also has anyone looked at midodrine ?
I am considering (not at the same time) 5HTP, TMG (not an aminoacid but... hey.. :p), Theanine, Tyrosine, Arginine (all with B1 and B6) Also I have been taking Glutamine.Do you have any comments/experience with the amino acids mentioned above ?
Quote from: mister_z on 18/10/2009 17:41:32has anyone done ECG, EEG, CT, MRI, blood pressure, glycemia, blood count, temperature, hormones right after orgasm?Exactly what needs to be done! I did MRI of the brain (pituitary) and some of the above, but a week after.
Laurac, they found a "partially empty sella", which didn't seem to concern the endocrinologist at all. He was looking for tumors and found none.
I originally tried five years ago with a physician, urologist, and endocrineologist who offered nothing.