Post Orgasmic Illness Syndrome (POIS)

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5850 on: 22/10/2009 00:12:46 »

Watson Pharmaceuticals certainly sounds like they are taking POIS seriously. Excellent news, Demo!


Many thanks, hurray! Keep in mind it's a giant corporation and as such, takes its time, and will need multiple staff approval.

But so far so good!! (And it doesn't hurt that I'm a walking testimony to their product working!)

************************************************************

By the way, I'm still pinching myself to see if I'm awake: since I increased my testosterone dose 50% AFTER hitting normal T-range, and supplemented that with a Day Zero increase in stimulants...I'm practically POIS-free now! 

It is simply unbelievable after 30+ years of wretched, ugly POIS!

I sincerely hope that this gives much hope to others!
« Last Edit: 22/10/2009 00:14:24 by demografx »

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Offline Looking_for_answer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5851 on: 22/10/2009 00:33:59 »

My POIS treatment

Lately, I've been able to maintain almost 100% POIS-free episodes (increased testosterone and increased adderall). Can't really explain it (the near-100%). Maybe the treatment is catching up and is in effect a "wholesale cure"!

Today, when Day Zero symptoms started creeping up, I forced myself out into the sunshine...and it worked! (My natural tendency on Day Zero is to maximize physical/mental passivity). Simplistic? You bet! [;D]

i believe there is fundamentally nothing wrong with us and drugs are just a quick way out.


Very interesting point of view, not sure I agree.


Anyone else have a thought about that?

Personally i think there is something wrong with us and that thing was dormant untill excessive pleasure aggravated. Untill we can find out what is wrong we dont know if drug will be a quick fix or it will take longer.  

Yes ok by 'fundamentally wrong' i mean something like a genetic deffect or something like that, ie that probably needs pills for life (for example, bad eyesight needs glasses/contacts for life or surgery). But i dont exclude that we might have had a dormant problem for quite some time before symptoms appeared, I just mean that i believe it can be cured by natural means.

For example, suppose that as a kid someone is (asymptomatically) chronically dehydrated, or drink milk every meal, or his mother had low zinc levels during pregnancy, or had some digestive issues because some enzyme werent produced sufficiently, etc and end up with a low level of zinc. then it would be dormant for a while and would only get exposed after many ejaculations. i would not call that a fundamental problem, but rather a fixable problem.

dont forget that pharmaceutical compagnies only want to make profit (duh) so they will tell you of a cure only if they can sell u enough pills, ie u arent made aware of possible natural treatment and u likely end up with a life pill requiremnt, not a short pill treatment (like antibiotics). im too young to accept that sentence already.

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Offline Looking_for_answer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5852 on: 22/10/2009 00:35:26 »
As anyone tried to taste zinc tally?

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Offline Looking_for_answer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5853 on: 22/10/2009 00:49:42 »

My POIS treatment

Lately, I've been able to maintain almost 100% POIS-free episodes (increased testosterone and increased adderall). Can't really explain it (the near-100%). Maybe the treatment is catching up and is in effect a "wholesale cure"!

Today, when Day Zero symptoms started creeping up, I forced myself out into the sunshine...and it worked! (My natural tendency on Day Zero is to maximize physical/mental passivity). Simplistic? You bet! [;D]

sorry if im confused, by day zero do u mean in the hours after sexual activity? and were you in the sun enough to actually see a change in skin color?

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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5854 on: 22/10/2009 00:51:30 »
Good to hear that you are still getting the better of POIS, Demo! My Fenugreek has all but killed the social anxiety component of POIS I used to suffer from, and as a bizarre side-effect my hair is always really glossy and lustrous - well, I'm not complaining :)

Like you Demo I am cautiously optimistic about the latest developments. But I think Watson could do very well from researching a POIS drug. Although many posters here suffer POIS acutely, I believe that POIS is a sliding scale, and potentially millions of people may suffer from a milder form of POIS which could also be treatable.

If you posed the question "Have you ever suffered from sexual exhaustion?" to 100 people, I bet a reasonable number of them would answer "yes".

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Offline Looking_for_answer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5855 on: 22/10/2009 01:08:08 »
ok last post for now.

if people wish, we could have a post with symptoms that everyone could quote and add all of his own health problems, even the ones he believes are totally unrelated to POIS and equally "embarrassing", like having testicules that shrink too much at the gym. Then if someone is computer litterate enough, we could turn the lists of all problems/symptoms into a survey in which we could vote on each item that affect us. End result would be a huge list of health problems/symptoms and their frequencies among POIS sufferes.. we could have surprises.


i was trying to make a short list myself, so i was reading page 247. i saw adrenal/chronic fatigue, immune system deficiencies, low testosterone, concentration/memory issues. i know im annoying with my zinc but i cant help to notice that these are the main effect of a zinc deficiency. Also 2-3 members on that page talked about alcolism, one of the leading cause of zinc deficiencies. I think a survey as mentionned above could really help. and every new member, in the introduction message, could be invited to take part in it. so it would keep evolving.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5856 on: 22/10/2009 06:51:24 »

My POIS treatment

Lately, I've been able to maintain almost 100% POIS-free episodes (increased testosterone and increased adderall). Can't really explain it (the near-100%). Maybe the treatment is catching up and is in effect a "wholesale cure"!

Today, when Day Zero symptoms started creeping up, I forced myself out into the sunshine...and it worked! (My natural tendency on Day Zero is to maximize physical/mental passivity). Simplistic? You bet! [;D]

sorry if im confused, by day zero do u mean in the hours after sexual activity? and were you in the sun enough to actually see a change in skin color?

Yes and no.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5857 on: 22/10/2009 06:55:14 »
LFA,

1. Have you read through our previous discussions about zinc?
http://www.google.com/search?q=zinc+POIS+site:http://thenakedscientists.com&ie=UTF-8&oe=UTF-8&hl=en&client=safari

2. Did you see our online POIS survey questionnaire to see if you can recommend adding to it?

Both were discussed in your welcome post.
« Last Edit: 22/10/2009 07:05:38 by demografx »

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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5858 on: 22/10/2009 18:16:38 »
Welcome new sufferers .
We exceeded the number of 300 cases.
Hi, hurray. It's amazing that fenugreek helps you with social anxiety.    
It would be nice to talk about this with other social anxiety sufferers (Non-Pois).
Do you take 3 caps a day every day or just after ?
I will retry fenugreek extract after glutamine test.


I take one cap of Solgar Fenugreek (370mg raw fenugreek seed powder, 150mg fenugreek seed powdered extract) every day while in POIS, although I will often take it outside POIS for its positive social effects. I also take a couple of caps before and after orgasm as a precaution, it does help with the immediate after-effects but it isn't a 100% cure.

Fenugreek is supposed to help the body produce oxytocin (it is used by nursing mothers to encourage milk production) which could explain its effects - another theory is that it is a precursor to estrogen, which is thought to enhance sociability.

Good idea B_Jim - you would imagine that social anxiety sufferers would have discovered fenugreek themselves, but a quick google search didn't bring much up. Perhaps I should join a forum and ask around.

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5859 on: 22/10/2009 21:25:41 »
Welcome new sufferers .
We exceeded the number of 300 cases.
Hi, hurray. It's amazing that fenugreek helps you with social anxiety.    
It would be nice to talk about this with other social anxiety sufferers (Non-Pois).
Do you take 3 caps a day every day or just after ?
I will retry fenugreek extract after glutamine test.
---
I had an orgasm 3 days ago and I catch a cold the day after... There is really something wrong with immune system.
The tempeartures are cooler here and I feel much more sensitive to cold during the first hours dispite I have no more fevers (8-15 hours later) or diarrheas (3-7 hours later)since i stopped sugar.



That same thing happend to me, i did three big O's, and after every Big O my temprature went up and felt more sick but went a way after sleep. 
and then 2 days later i get the a flu without big O that last two days.   
This never happend during the summer i just got hot for mins and body temprature was back to normal.

i was scarred i thought got swine because i never get sick.   

Am in line with you here.
flu like symptoms
headaches
fatigue.
seems to lead to immune dysfuction.

so will it be the immune system is to strong or the immune system gets weaken after pois. or a totall different story.
« Last Edit: 22/10/2009 21:29:47 by CCconfucius »

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5860 on: 22/10/2009 21:35:53 »
I was wondering if you guys can please Pm me the outside reasearch that you have done.  i want links, books. I am going to start doing some extensive reasearch and i want to know where to start and what to skip.
I will start with alcohol+weightgain+immunesystem.
alcohol and weight gain were the two main things that change in my life when i noticed full effects of pois.

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5861 on: 23/10/2009 04:38:42 »
MUST CHECK OUT/ 2ND TO THE LAST PARAGRAPH.
http://www.nutramed.com/immunology/mediators.htm, -
This website talks about cytokins and interlukins and how they affect thinking.
« Last Edit: 23/10/2009 04:41:41 by CCconfucius »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5862 on: 23/10/2009 06:28:16 »

I had an orgasm 3 days ago and I catch a cold the day after... There is really something wrong with immune system.


B_Jim, in my earlier years of POIS, I was constantly getting colds the day after, until I learned to keep my physical and mental activity/output to a bare minimum. That worked for me very well. (But I became a zombie).

I agree, it always felt like orgasm immediately lowers the proper functioning of the immune system: a sudden and very strong feeling of susceptibility to colds and flu.
« Last Edit: 23/10/2009 06:35:04 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5863 on: 23/10/2009 06:33:41 »

We exceeded the number of 300 [POIS] cases.


Great to hear!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5864 on: 23/10/2009 06:38:18 »

I was wondering if you guys can please Pm me the outside reasearch that you have done.  i want links, books.


Doesn't the welcome-newcomer post contain all that?

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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5865 on: 23/10/2009 12:12:59 »
Personally I rarely get flu, but have allergies. I had allergies before my first orgasm which could eventually cause a tendency to develop POIS (?)
The flu-like symptom described by some of you in POIS does not appply to me or I don't have enough experience with flu. I'd say I'm just very tired after a short effort in POIS.

Do you get flu the day after or immediately?
Bad sleep weakens the immune system and has often been reported in POIS.

I forgot to report that after a nocturnal emission I always have half sleep for the rest of the night with very pronounced racing mind, I can't relax.
« Last Edit: 23/10/2009 12:18:51 by martin88 »

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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5866 on: 23/10/2009 12:48:50 »

Watson Pharmaceuticals
Our contact promised to write up a possible POIS study scenario and send it on to a company committee that meets several times a year for consideration.
I wrote again today asking when I can call to follow up with Watson to see what our status is.
Great efforts Demo, hope this will work!

Good to hear that you are still getting the better of POIS, Demo! My Fenugreek has all but killed the social anxiety component of POIS I used to suffer from.

I believe that POIS is a sliding scale, and potentially millions of people may suffer from a milder form of POIS which could also be treatable.
I think my sociability is not changed in POIS, but since my cognitive problems will eventually be noticed by people this is causing social anxiety.
Maybe we have excessive dopamine out of POIS and not enough in POIS, like hyperglycemia followed by hypoglycemia. Fenugreek is reducing dopamine..

I believe a lot of cases of depression can be undiagnosed POIS.

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Offline mister_z

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5867 on: 23/10/2009 13:44:02 »
I believe a lot of cases of depression can be undiagnosed POIS.

From what I have been reading so far, it would seem to me that starting at puberty the human brain is flooded with "random" spikes of hormones; which define our behavior for the rest of our lives. So, personally I believe ANYTHING that we do/experience from puberty until death is heavily influenced by our hormonal/neurotransmitter state.

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Offline mister_z

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5868 on: 23/10/2009 14:28:14 »
I was wondering and looking for a simple answer actually...

As far as blood pressure is concerned does dopamine lower or raise it?
How about serotonin? testosterone?

I have noticed that after orgasm when I dont get the shakiness, nausea, cold, sweats etc... I get irritable and eventually sad.
My father (after interrogation confessed that after orgasm he also feels sad)

Should I give SSRI (or SNRIs) a go? I tried Paxil a long time ago, gave me panic attacks so never finished the first 2 weeks of "adaptation". (same problem with imipramine)
The problem I have with SSRI/SNRI (and other psychoactive drugs) is the time they take to work and their addictive properties. I'm not sure I could be bothered to renew
prescriptions for such drugs.

I'd like to give testosterone patches a shot (even though it is my free testosterone that is low) just to briefly see how I feel on them. I wouldn't intend to stay on them for a long period also as I suspect that it would soon become useless as the testosterone would just get bound. Is there btw a proven way to unbind testosterone ?
I doubt my doctor would agree to give me testosterone even as a short trial because my free testosterone levels are indeed lower than normal range but not dramatically so; or should I insist ?

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Offline nsf

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5869 on: 23/10/2009 17:40:33 »
I have observed my blood pressure level goes up significantly in 24-hours after orgasm. It takes days, sometimes weeks, before feeling being back to normal. My BP readings goes beyond 150/90. Do anyone feel similar symptoms?

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5870 on: 23/10/2009 18:25:24 »

Quote
B_Jim, in my earlier years of POIS, I was constantly getting colds the day after, until I learned to keep my physical and mental activity/output to a bare minimum.


I agree. Many testimonies refers to "cold after sex". In fact, the  best thing to do is to sleep, if possible.


Yes, I agree! Sleep is the most effective tool. Naps, even for just a few minutes have often broken or at least reduced the POIS spell (hell!) for me!

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5871 on: 23/10/2009 18:30:11 »
I have observed my blood pressure level goes up significantly in 24-hours after orgasm. It takes days, sometimes weeks, before feeling being back to normal. My BP readings goes beyond 150/90. Do anyone feel similar symptoms?

that has happned to me once but i never checked after that.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5872 on: 23/10/2009 18:45:24 »

I doubt my doctor would agree to give me testosterone even as a short trial because my free testosterone levels are indeed lower than normal range but not dramatically so; or should I insist ?


I insisted. Insisting worked.

I suspect that taking more T than necessary, i.e., going beyond normal range might be the trick for POIS (vs. for hypogonadism, the usual treatment application). It certainly was for me. Just my theory, though! Not proven! Caution please, and work with an open-minded endo!

Insisting on treatment (I emphatically said it was for POIS, and said it loud and clear as if POIS were a major worldwide illness : - ). And this was 7 years ago! I was desperate, after 30 years of POIS Agony/Life Destruction and then finding a highly regarded Czech sex researcher who thought testosterone was the key to POIS. Insisting was necessary before working with my endocrinologist. No need to insist now.

I don't trust most T-testing. Prior to my current endo, my tests were mostly done badly with GP's and urologists, including one test that classified me as a female and said my T was too high!! (There is no way that my first name is even close to a female name!)

I trust the testing now (which includes much repeat testing of not just T (incl free T and bioavailable T), but related hormones such as LH) And I very much trust my endo - who was and is open to POIS, a very important point - and the University lab, which has a strong reputation.
« Last Edit: 23/10/2009 18:54:01 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5873 on: 23/10/2009 18:58:39 »

I believe a lot of cases of depression can be undiagnosed POIS.


I think goingcrazy would agree. I responded negatively to one of his posts about that, but maybe I was wrong.

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5874 on: 23/10/2009 19:07:52 »

I was wondering if you guys can please Pm me the outside reasearch that you have done.  i want links, books.


Doesn't the welcome-newcomer post contain all that?

It only contains what people have posted i want what hasnt been posted.

I want more material other than summaries.

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Offline mister_z

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5875 on: 23/10/2009 19:51:18 »
Anyone suggested starting a wiki yet?

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Offline demografx

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5877 on: 23/10/2009 19:56:00 »

CC, everything I know is posted. After 3 years, you think we've missed some major non-posted references? If so, where would we, or anyone, start to look?

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5878 on: 23/10/2009 21:25:04 »
nsf,
As I mentioned, temporary high blood pressure in the POIS state was a definite symptom for me, at least some of the times.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5879 on: 23/10/2009 21:52:23 »

I'm not sure I can contribute intelligently to the BP discussion, since I'm on (very effective) blood pressure meds.

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Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5880 on: 23/10/2009 23:16:45 »

I believe a lot of cases of depression can be undiagnosed POIS.


I think goingcrazy would agree. I responded negatively to one of his posts about that, but maybe I was wrong.

    Maybe depression could be a big hoax, and it just really is POIS, but you never know.  I mean, why do you think they invented anti-masturbation devices in the past?  There's got to be some explanation towards it.

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Offline lauracostis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5881 on: 24/10/2009 03:45:49 »
i can ethier get low blood pressure and cognitive problems/brain fog or high blood pressure and anxiety.

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Offline lauracostis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5882 on: 24/10/2009 04:09:53 »
i put ".75cc im" of "T" into my system yesterday evening for test purposes. i usually test T after "O" once in a while, but i have not o'd in 10-12 days.  i felt good today cleaned my house, washed all dirty cloths, ect...  but i can still feel the horible simptoms lurking just under the surface, that are just being masked by "T" not cured.  the positive effects will start to diminish over the next day or two, but for now i will take advantage of extra energy.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5883 on: 24/10/2009 04:10:57 »

    Maybe depression could be a big hoax, and it just really is POIS, but you never know.  I mean, why do you think they invented anti-masturbation devices in the past?  There's got to be some explanation towards it.


The devices had to do with "morality" and enforcing someone's opinion of what constitutes 'good behavior' and avoiding 'evil behavior', not to heal depression.

I have a history of depression, and now that I'm wise to POIS, I'm sure that at least SOME of my past depressions were POIS-related, and I just didn't know it at the time.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5884 on: 24/10/2009 04:25:12 »

I put ".75cc im" of "T" into my system yesterday evening for test purposes. I usually test T after "O" once in a while, but I have not o'd in 10-12 days.  I felt good today, cleaned my house, washed all dirty clothes, etc...  but I can still feel the horible symptoms lurking just under the surface, that are just being masked by "T" not cured.  The positive effects will start to diminish over the next day or two, but for now I will take advantage of extra energy.


If no sex activity for 10-12 days, why are POIS symptoms "lurking"? Do your POIS symptoms last 2 weeks?

I feel there's a cure with T for me and it's somehow associated with speeding up sperm re-generation. But I can't prove it yet. Strong hunch. But even if worst case were true, and T is only "masking" symptoms, I'll take it. It's a cure for me.

These days, I'm functioning as a human being like I never did in my whole life. I never dreamed this was possible. And it's been holding now for about one year!

Today, Day Zero, was not as good for me as the last 5-6 times. A strong nap (over an hour) was necessary for me this afternoon to re-stabilize.

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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5885 on: 24/10/2009 13:18:49 »

I believe a lot of cases of depression can be undiagnosed POIS.


I think goingcrazy would agree. I responded negatively to one of his posts about that, but maybe I was wrong.
Maybe depression could be a big hoax, and it just really is POIS, but you never know.  I mean, why do you think they invented anti-masturbation devices in the past?  There's got to be some explanation towards it.
Definitely POIS is not the cause of all depressions but I believe that for me it was, directly and indirectly the cause.

About blood pressure I have 100/70 which is normal according to MDs. But in POIS I feel dizzy when I stand up too quickly. Probably this is orthostatic hypotension. When I searched for this I found it can be caused by this:

Another disease [cause]is called Dopamine beta hydroxylase deficiency, that is thought to be underdiagnosed also, that causes loss of sympathetic noradrenergic function and is characterized by a low or extremely low levels of norepinephrine but an excess of dopamine.  http://en.wikipedia.org/wiki/Orthostatic_hypotension

Since other pois sufferers have high blood pressure maybe this is not important.(or I'm in POIS stage V...)

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Offline mister_z

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5886 on: 24/10/2009 13:28:50 »
About blood pressure I have 100/70 which is normal according to MDs. But in POIS I feel dizzy when I stand up too quickly. Probably this is orthostatic hypotension. When I searched for this I found it can be caused by this:

Another disease [cause]is called Dopamine beta hydroxylase deficiency, that is thought to be underdiagnosed also, that causes loss of sympathetic noradrenergic function and is characterized by a low or extremely low levels of norepinephrine but an excess of dopamine.  http://en.wikipedia.org/wiki/Orthostatic_hypotension

Since other pois sufferers have high blood pressure maybe this is not important.(or I'm in POIS stage V...)

Now THIS is interesting... I shall study that and try out some ideas.

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Offline mat780

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5887 on: 24/10/2009 18:49:46 »
Welcome new sufferers .
We exceeded the number of 300 cases.
Hi, hurray. It's amazing that fenugreek helps you with social anxiety.    
It would be nice to talk about this with other social anxiety sufferers (Non-Pois).
Do you take 3 caps a day every day or just after ?
I will retry fenugreek extract after glutamine test.
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I had an orgasm 3 days ago and I catch a cold the day after... There is really something wrong with immune system.
The tempeartures are cooler here and I feel much more sensitive to cold during the first hours dispite I have no more fevers (8-15 hours later) or diarrheas (3-7 hours later)since i stopped sugar.



B_Jim, I agree with most of what you said. Thereís definitely a relation between having an orgasm and an immune system weakness. I usually get a cold after having an orgasm, mostly in winter.


I was wondering if you guys can please Pm me the outside reasearch that you have done.  i want links, books. I am going to start doing some extensive reasearch and i want to know where to start and what to skip.
I will start with alcohol+weightgain+immunesystem.
alcohol and weight gain were the two main things that change in my life when i noticed full effects of pois.


CCconfucius, Iíve been in good shape all my life, and I never drink alcohol more than just a few times a year and in very small quantities. So, in my case, you can discard the combo alcohol+weightgain+immunesystem.

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Offline lauracostis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5888 on: 24/10/2009 19:52:03 »

I put ".75cc im" of "T" into my system yesterday evening for test purposes. I usually test T after "O" once in a while, but I have not o'd in 10-12 days.  I felt good today, cleaned my house, washed all dirty clothes, etc...  but I can still feel the horible symptoms lurking just under the surface, that are just being masked by "T" not cured.  The positive effects will start to diminish over the next day or two, but for now I will take advantage of extra energy.


If no sex activity for 10-12 days, why are POIS symptoms "lurking"? Do your POIS symptoms last 2 weeks?

I feel there's a cure with T for me and it's somehow associated with speeding up sperm re-generation. But I can't prove it yet. Strong hunch. But even if worst case were true, and T is only "masking" symptoms, I'll take it. It's a cure for me.

These days, I'm functioning as a human being like I never did in my whole life. I never dreamed this was possible. And it's been holding now for about one year!

Today, Day Zero, was not as good for me as the last 5-6 times. A strong nap (over an hour) was necessary for me this afternoon to re-stabilize.
i have symptoms of adrenal fatigue/cognigitive dysfunction and insomnia all the time, out of pois just means my symptoms are better. i would still be sick even if i never o'd again, o'ing just makes my life even more unberable.  it is possible that my pois is a secondary symptom from some type of chemical deficit. i think of my body/physiology as being a working deficit.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5889 on: 25/10/2009 00:28:12 »
Laurac, I'm really sorry to hear about your condition. It sounds like "POIS+++" !

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5890 on: 25/10/2009 00:30:12 »

CC, everything I know is posted. After 3 years, you think we've missed some major non-posted references? If so, where would we, or anyone, start to look?

I think instead of thinking of pois as been caused by multiple things, we should look at it as sometthing caused by one thing.  In order to do that we need to find out what disorder can cause all the symptoms mentioned, major and minor.  And to find that out we need to go deeper in some of our reasearch.
I am going to start with immune system because i have already done hormone test and because of chemobrain,flu like symptoms and because it affects neuroendocrine and other parts of the body.

I think  this is caused by one thing because we are unique in the sense that this symptoms comes after orgasm.  
« Last Edit: 25/10/2009 00:41:59 by CCconfucius »

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5891 on: 25/10/2009 00:35:37 »
I was thinking what if it is not necessarily overproduction or underproduction of anything but lack of enzyme that breaks down a chemical produce after orgasm or a chemical always in our body.

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Offline Finally

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5892 on: 25/10/2009 01:13:50 »
I was thinking what if it is not necessarily overproduction or underproduction of anything but lack of enzyme that breaks down a chemical produce after orgasm or a chemical always in our body.

I was reading an article about how alcohol is handled in our body.  In order to  eliminate it has to be changed to acetaldehyde through enzymes produced in the body.  This occurs in the Stomach and liver.  One of these alcohol dehydrogenase is produced more by men than women.  One thing that is interesting is that substances used for detoxification for alcoholics heavy use is very similar to those  used for erectile Dysfunction.  They work by inhibiting the chemical that is released at orgasm which causes the refractory period.  Didn't some report limited success with Levitra?
Ironically POIS has been called sexual hangover and some have reported simlar symptoms from alcohol consumption as after orgasm.  Perhaps  enzyme activity  needed to return the body to original balance is very similar.
 Maybe the difference between men and women could mean that Testosterone levels may play a role in production and release of these Enzyme(s).
Maybe it is a reach but we have had a wide range of theories.

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Offline POIS-SUFFERER

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5893 on: 25/10/2009 03:24:44 »
Does anyone get itchy skin on face and scalp, or muscles twitch in the noise area and face after "O".... I do and its annoying. Goes away if no "O" for about 7-10 days.... most annoying right after....

I know the itchy skin or the "bugs" or "ants" crawling on your face is a sign of MS... so I wonder if "O" might be affecting per-MS symptoms.... hope not.

PS.

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Offline pauliebaby61

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5894 on: 25/10/2009 04:27:37 »
I have seen a few people reporting good results using antihistamines. Could any of the users tell how and when it is taken? I would like to try this. The last O i had, the awful fatigue and symptoms lasted 3weeks. It was terrible.
Also, I am happy some are getting results with Testosterone, but it was not the answer for me. I had a T level of 109 1 yr ago. I have been on injectable T, .375 dosage 2x a week for 12 months now. My level is now 896, which is excellent for a 48yr old man, but it has done nothing for the pois, just has increased libido. I have speculated that this was adrenal dysfunction also, but i have been on hydrocortisone for yrs, and a short trial of prednisone,and still suffering with pois.
I am currently doing a program[with my Dr.] of T shots, dhea, 5htp, and a drug that stops the conversion of T into estogen. so far, no change in symptoms, but I have had fatigue issues for years aside from the pois stuff, probably cause by lyme disease that went untreated for 25 yrs before it was discovered.
I am now leaning towards the theory that after O's, there is a release of histamine from the mast cells, causing some type of allergic reaction in the body. This may explain why some are benefitting from the use of antihistamines. Im am ready to try taking one, but am fearful of the pois for 3wks if this does not work.
Can you guys that have got results with antihistamines tell me what brand, and when you take them[before sex, after...] thx

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Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5895 on: 25/10/2009 10:33:01 »
has anybody checked for any kind of adrenal tumors, I think adrenaline just may be released too much after sex.  All my POIS is now is a rush of adrenaline and energy or something that keeps me up at night, thats why i'm posting here at 6 in the morning

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5896 on: 25/10/2009 19:56:48 »


I think instead of thinking of pois as been caused by multiple things, we should look at it as something caused by one thing.  


CC, if that's true, then in my case, the "one thing" causing my POIS would be hypogonadism, i. e., my body produces insufficient tosterone.
« Last Edit: 25/10/2009 21:55:04 by demografx »

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Offline mister_z

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5897 on: 25/10/2009 20:41:59 »
I am sort of afraid that in my case that the answer may be quite simple and depressing

I doubt my answer would apply to any of you guys.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5898 on: 25/10/2009 21:58:42 »

Has anybody checked for any kind of adrenal tumors, I think adrenaline just may be released too much after sex.  All my POIS is now is a rush of adrenaline and energy or something that keeps me up at night, thats why i'm posting here at 6 in the morning


I do notice a rush of energy immediately afterwards, whereas the "normal" response for guys is to roll over and snooze.  [;D]
« Last Edit: 25/10/2009 22:48:10 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5899 on: 25/10/2009 22:01:40 »

I am sort of afraid that in my case that the answer may be quite simple and depressing

I doubt my answer would apply to any of you guys.


You never know. Please post it or PM one of us privately. We're all here to learn from each other! Maybe your answer will spark some new ideas!
« Last Edit: 25/10/2009 22:46:24 by demografx »