[Animus]

why does it take around 7 days to recover from POIS?

My theory - but far from fact - is that very slow sperm regeneration time (SRT) causes the long recovery.

Since TRT, my SRT is now very quick, and POIS is vastly reduced. When I'm "full" (again), I'm fine.

Anyone agree/disagree?

I agree... I think it has to do with sperm and semen regeneration too. I was looking up the time it takes to make sperm, and found that it takes about 74 days, and is being done all the time, but it takes 2-6 days for the sperm to make their final journey and mature fully... the article is here:  http://www.ehow.com/about_5503589_long-sperm-mature.html

So I found that interesting because it seems to match the time it takes to recover...

[Guthrie]

...everything is in ranges except for: D3-low...

Another case of low Vitamin D!

[horizon]

hi demo,
can you email me that waldinger study?
thanks

Sure. For PDF, PM me your regular email. OR for just plain text embedded in long PM, email not needed. Let me know which is preferred.

text version as a PM would be great
thanks!

Sent.

never received it in my inbox(?)

[demografx]

Maybe poor internet connection where I'm staying? I'm traveling next 4 days w/iPhone no puter.

Can anyone else send Waldinger study to horizon, embedded in his PM? Thank you.

[demografx]

why does it take around 7 days to recover from POIS?

My theory - but far from fact - is that very slow sperm regeneration time (SRT) causes the long recovery.

Since TRT, my SRT is now very quick, and POIS is vastly reduced. When I'm "full" (again), I'm fine.

Anyone agree/disagree?

I agree... I think it has to do with sperm and semen regeneration too. I was looking up the time it takes to make sperm, and found that it takes about 74 days, and is being done all the time, but it takes 2-6 days for the sperm to make their final journey and mature fully... the article is here:  http://www.ehow.com/about_5503589_long-sperm-mature.html

So I found that interesting because it seems to match the time it takes to recover...

Animus, fascinating find re 2 - 6 days! Thanks!

[GoingCrazy]

I took some Claritin Clear, antihistamine yesterday, and man, I am never doing that again.  My POIS, as I've said before, comes in 2 stages, 1st is emotional (terrible mood, I want to kill somebody) , 2nd is mental (brain fog).  I haven't O'd in 15 days and took it on the 14th day.  Always as I "O", my brain fog stage turns into the emotional stage.  As I took the antihistamine, this had happened, very weird.  Thinking was crystal clear, but mood was the worst ever.
Testosterone, or should I say demografx  [)], I would try it, but I am a teenager with acne, and I think testosterone would probably be worse for me to take... right?  I believe I am full of it now.
Somebody else try claritin clear or an antihistamine (preferrably c.c. though) and see how they feel.

[RhythmSpring]

For the record, my POIS used to last about a week, but then it grew to 2 weeks for a while, and then gradually went to 4 weeks. Now, it's been a little over one month since my last O, and I'm just now starting to feel better.

[Animus]

Maybe poor internet connection where I'm staying? I'm traveling next 4 days w/iPhone no puter.

Can anyone else send Waldinger study to horizon, embedded in his PM? Thank you.

sure, I can send it-

[Animus]

demographx, do you have a letter which you send to potential POIS researchers? I once sent out about 50 letters to urologists in New York, and I got one response referring me to a specialist. I am going to start up this process again.
Also, has someone compiled the survey data into a short form? Like a summary?
In a way we've done a lot of our own research and testing, and it would be good to document it. I am interested in doing that, will get started right away.

Martin88 makes an excellent point: we get the best results from Directors, Managers, i.e., generalists, rather than researchers. Of course, in some cases, we have no choice when it's an independent researcher.

Feel free to use/modify:

Dear Dr./Mr./Ms. X,

We would like to know if you would be interested in helping to research a serious new medical condition (described below). The smallest suggestion, idea, opinion or ideally a proposition from you to initiate some research, would be very welcome and appreciated. We already have a group of sufferers who would be willing to participate in a study.
 
The first cases were officially described in 2002, by Dr. Marcel Waldinger (MD PhD) and endocrinologist Dr. Dave Schweitzer, MD.(http://www.ncbi.nlm.nih.gov/pubmed/11995603).  He referred to the condition as "Postorgasmic Illness Syndrome" (POIS). His study results are attached.
 
Essentially, those with POIS usually suffer debilitating symptoms that follow within minutes of orgasm, and last for days. The symptoms include severe fatigue, anxiety, and cognitive impairment.
 
About 300 cases can be found directly (or are linked) on a UK Science forum, "The Naked Scientists", which is administered by a Cambridge medic.  Other cases are being increasingly described by the ISSM (International Society for Sexual Medicine).
 
Please consider this carefully.  A helpful response could save lives.  If you have any questions, or need more information, please ask.
 
Best regards,
 
[Your username]
[or first name, surname initial - -
or full name if you're comfortable]
POIS Forum
h t t p : / / t i n y u r l . c o m / d 3 u v 8 8 [without spaces]


And please don't forget to add to Martin88's database:
http://pois.vndv.com/email_list.php

Thanks for posting this useful letter, demo.

[horizon]

post-orgasm related studies
Stuart Brody of the University of Paisley, UK, and Tillmann Krüger of the Swiss Federal Institute of Technology in Zurich
http://www.newscientist.com/article/mg18925405.900

also Aliisa K. Humphries¹ and Jan Cioe¹
¹ Psychology Department, University of British Columbia Okanagan, Kelowna, BC
are doing/have done post-orgasm studies
http://www.sieccan.org/abstracts/vol18no3.html
http://web.ubc.ca/okanagan/psyo/faculty/cioe.html
(not exactly what we are looking for but there you go)

[daveman]

I took some Claritin Clear, antihistamine yesterday, and man, I am never doing that again.  My POIS, as I've said before, comes in 2 stages, 1st is emotional (terrible mood, I want to kill somebody) , 2nd is mental (brain fog).  I haven't O'd in 15 days and took it on the 14th day.  Always as I "O", my brain fog stage turns into the emotional stage.  As I took the antihistamine, this had happened, very weird.  Thinking was crystal clear, but mood was the worst ever.
Testosterone, or should I say demografx  [)], I would try it, but I am a teenager with acne, and I think testosterone would probably be worse for me to take... right?  I believe I am full of it now.
Somebody else try claritin clear or an antihistamine (preferrably c.c. though) and see how they feel.

Hey GC,

Yeah, my trials with antihistamine (which compound is in Calritin Clear?) have been mixed at best. My emotional state is little effected by POIS, althugh I do get brain fog, so I haven't noticed any "depressive" effects. But I'd have to say that anti/histamines make it more worse than better.

On the other hand, I have found that noscapine ( in hot lemon cold/flu remedies ), especially on day 1 does wonders! I'd say that it does more than just help local symptoms, I'd have to say that it seems to reduce the length of the POIS session. Might be just a coincidence, but I 'O'd the night before last, took the cold remedy yesterday and today feel only about 5% POIS symptoms!! Go figure!

[Puscar]

TEMPORARY SOLUTION FOR POIS
Guys, I am glad I found this site today and also discovered the term POIS today as well.  I have been trying to resolve my POIS for the last 5 years. I am 26 and athletic. I suffer ED and PE as well. Here's what ELIMINATES the POIS symptomps. Do intense sports and sweat heavily. Either a 50 plus laps of nonstop swim, or a 8 km run at least will eliminate the symptomps completely and get me to normal IMMEDIATELY as though I had no pois at all. But this only undoes the sympotomps and of course does not resolve the root of the problem permantently.

I am sure it works for you as well. Try it. Cardiac Exercise gets the blood going through the brain. Resistance exercise or walking or cycling does not work here. Lemme know if it works for you as well. This way you can avoid having to wait for many days to recover.
 

[Puscar]

For the record, my POIS used to last about a week, but then it grew to 2 weeks for a while, and then gradually went to 4 weeks. Now, it's been a little over one month since my last O, and I'm just now starting to feel better.

[Hoping]

Hello all!
This is only my second post in the forum. As I stated earlier, I am a 25-year-old male and have suffered from POIS for the past 8 years. I would say that the symptoms have become SEVERE over the last 3 years.
I realize that there are several conversations going on in the forum right now, but I just wanted to quickly report that I have recently started consuming raw garlic as a treatment for POIS. User John21 originally reported success with this method (pages 42-47 of the forum), and I know others have tried it as well.
I am happy to report that it seems to be helping with my symptoms quite a bit. I was extremely skeptical, but figured it wouldn't hurt to try. I sliced up and swallowed a clove of garlic within a half hour of O'ing two days ago. I have been consuming a clove in the morning and before bed since then. Although I was very hesitant, I O'ed again last night (busy week! []) and have felt very few POIS symptoms. I have tried so many things and this is the first that has shown any promise. I strongly encourage others to try it even if you are skeptical. It is easy and inexpensive.

Method:
-Peel and slice the clove in half along the back "spine". Slice each half into at least 6 pieces (12 small pieces total). This make it easier to swallow and easier to digest.
-Take a big gulp of water (or whatever liquid you prefer) and hold it in your mouth without swallowing it. Then, tilt your head up and drop a piece or two (or three!) of garlic in your mouth and swallow it immediately like a pill. Holding a mouthful of water before putting the garlic in your mouth prevents the garlic from touching the inside of your mouth and greatly reduces any sort of garlicky taste or bad breath.
-Repeat until you have consumed the entire clove.

I have thought about purchasing garlic pills but have yet to do so. I don't want to change anything yet if it seems to be working.

*as a side note I am also currently taking a low dosage of Wellbutrin for depression and vitamin D tablets. I have been taking these for over a year without noticing much improvement in my POIS symptoms

[demografx]

For the record, my POIS used to last about a week, but then it grew to 2 weeks for a while, and then gradually went to 4 weeks. Now, it's been a little over one month since my last O, and I'm just now starting to feel better.

RS, very sorry to hear that! And thank you for reporting it.

[Guthrie]

*as a side note I am also currently taking...vitamin D tablets.

mmac06, were taking the vitamin D because you had been diagnosed from test results as having low vitamin D?   If so, that makes the 4th case of low vitamin D (three of which were posted here just within the span of the past week!).

[GoingCrazy]

For the record, my POIS used to last about a week, but then it grew to 2 weeks for a while, and then gradually went to 4 weeks. Now, it's been a little over one month since my last O, and I'm just now starting to feel better.

Wow, it grew for you?  Mine went from about 2 weeks to 2 days (the worst part at least).

TEMPORARY SOLUTION FOR POIS
Guys, I am glad I found this site today and also discovered the term POIS today as well.  I have been trying to resolve my POIS for the last 5 years. I am 26 and athletic. I suffer ED and PE as well. Here's what ELIMINATES the POIS symptomps. Do intense sports and sweat heavily. Either a 50 plus laps of nonstop swim, or a 8 km run at least will eliminate the symptomps completely and get me to normal IMMEDIATELY as though I had no pois at all. But this only undoes the sympotomps and of course does not resolve the root of the problem permantently.

I am sure it works for you as well. Try it. Cardiac Exercise gets the blood going through the brain. Resistance exercise or walking or cycling does not work here. Lemme know if it works for you as well. This way you can avoid having to wait for many days to recover.

I've been exercising a lot and do notice a positive change in mood, as long as I don't over-exert myself.  I plan to run in a 5K race this Saturday.  In short, I've been trying all that I can to stay on a positive track.  It does help POIS immensely.

I find it also weird that I don't share symptoms with anybody (1) my terrible mood, 2) than the physical brain fog in front of head symptom), it just seems so evident and might explain that their are differences with our POIS, and what helps POIS in one, may be totally different for what helps POIS in another.

[demografx]

post-orgasm related studies
Stuart Brody of the University of Paisley, UK, and Tillmann Krüger of the Swiss Federal Institute of Technology in Zurich
http://www.newscientist.com/article/mg18925405.900

also Aliisa K. Humphries¹ and Jan Cioe¹
¹ Psychology Department, University of British Columbia Okanagan, Kelowna, BC
are doing/have done post-orgasm studies
http://www.sieccan.org/abstracts/vol18no3.html
http://web.ubc.ca/okanagan/psyo/faculty/cioe.html
(not exactly what we are looking for but there you go)

Teriffic, Horizon! Any email addresses available?

[demografx]

Puscar, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:


Our new POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
http://forums.delphiforums.com/POIS/chat

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here.
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only formal medical investigation on POIS by Dr. Marcel Waldinger,MD and Dr. Dave Schweitzer, MD.

There are 2 ways to get it: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF. Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 3 years, our POIS forum has attracted over 150 POIS sufferers worldwide who have posted here, plus over 700,000 page visits. Not bad for a rare malady!

[demografx]

Puscar, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: 3 years' worth of posts (over 7,000 posts!) from 150+ Forum members, and an additional 150 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
demografx POIS site:http://thenakedscientists.com/

and 1,000+ results came up for "demografx" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.