[demografx]

I apologize if some news about Prof. dr. Waldinger's new research is being temporarily discouraged, but he wishes to announce the news himself to us at our forum on Monday, without any potential  distortions that may be reported.

Thank you everyone very much for your cooperation!

do you know what time that is happneing so i can get up, i love sleeping but this time around i will stay up all night starting today.

CC, it's not known, but I will ask him this weekend.

He just informed me that he anticipates the announcement sometime Monday morning, Dutch time.

[nick2k22]

My theories are
1>allergic reaction to something released during O
2>failure to metabolize something released after O
3>dysfunction of some hormonal pathway after O

I'm looking forward to tomorrow.

[daveman]

My theories are
1>allergic reaction to something released during O
2>failure to metabolize something released after O
3>dysfunction of some hormonal pathway after O

I'm looking forward to tomorrow.

My vote is 1 first, then 3.

[demografx]

Now where is Jimmy The Greek now that we need him? []

[Finally]

I would also like to see a more typical case if there is one.

There are more typical cases and that was my point...  John21 and Demografx would be examples.  But there is no point in arguing over this. You seem to have a sense of what the common symptoms are, which is good.  Also, I don't think the onset of POIS being near puberty has as much to do with 'genital development'.  Rather, it is because they are able to achieve orgasm.

Edit: I am sorry for somewhat misrepresenting your situation in my haste to 'make things right'.

I don't know about you, but I was able to achieve orgasm well before I ever reached puberty. I think I was masturbating as early as 4 years old. And I have heard the same is a common thing. Which actually brings up a good point about whether this should be called Post Ejaculatory Illness Syndrome!

Thank you for your apology- no offense taken!

This is an interesting point.  I definitely could not achieve orgasm until I was about 14, and my symptoms started shortly after -- about 6 months after.  I have heard about other cases of people being able to get orgasm when they are very young though (about 4 years old).  The huge difference in age has some interesting developmental implications.  The people who told me this were quite surprised when I told them that I was about 14 -- which I think is fairly normal.

As far as ejaculation vs orgasm... I have thought about this quite a lot.  I used to suppress ejaculation from wet dreams, in the hope that it would improve or stop symptoms from occurring.  The symptoms were still quite bad, so I concluded that (in my case) it was the neuro-chemical trigger of orgasm that was at the root of the problems.

Started having NEs at about 12 or 13. I do remember having flulike symptoms and a stiff neck after one
 Didn't masturbate until 14.  Pois symptoms then were mild if any.  They really began at 18.
How do you stop ejaculation in a wet dream?    I never realize it until I wake up.
and it is too late.

[Counterpoints]

My theories are
1>allergic reaction to something released during O
2>failure to metabolize something released after O
3>dysfunction of some hormonal pathway after O

I'm looking forward to tomorrow.

There could be different explanations for different variants of POIS....

[demografx]

                                                ANNOUNCEMENT OF

                                        PROF. DR. MARCEL  D. WALDINGER

                                                 January 17, 2011

Dear Members of this POIS Forum,
 
For reasons of confidentiality regarding the publication of our article and in order to get the required attention of the media, it has been necessary to maintain strict silence the last few months on the results of our research.
 
Before explaining our results, I  would like to compliment Demografx for his understanding of how things are going when an important scientific publication is at hand. And I also would like to compliment and congratulate Demografx for his impressive accomplishment to have developed this website and making it to a success. No doubt, that probably all of you, will agree with that.

Today, I publish two articles on POIS in the Journal of Sexual Medicine. The first article is about the characteristics of POIS and our hypothesis. The second article is about its treatment.

After 8 years of research, we have found that the various complaints of POIS are due to an immunological reaction of a man to his own semen. Interestingly, as long as the semen is stored in the testis there is no problem. However, as soon as the seminal fluid is released towards and into the urethra the various complaints will occur within a few minutes, and in the majority of our population of men within 30 minutes after ejaculation. But there are also men in whom the complaints start after a few hours.

Briefly, POIS  actually appears to be a systemic immune reaction that occurs only at the moment that semen is ejaculated towards or through the urethra.
 
In order to get hard evidence for this, we have performed a skinprick test with a man’s own (but very diluted) semen in his forearm. In more than the majority of men this has resulted in a positive allergic skin reaction and vague complaints of POIS.

But by saying this, I have to warn all of you. Don’t do this by yourself as a sort of experiment  with your own body without medical expertise. Own semen injection may lead to serious allergic reactions and even a (anaphylactic) shock, e.g. acute severe and life-threatening lowering of blood pressure, urging for acute medical aid. 

Skinprick testing is only safe in hands of a medical professional and with adequate equipment in case that an emergency may happen. The best approach is that a physician performs a skinprick tests with diluted semen in a well-equipped hospital.

The procedure and the results of this skinprick test is described in the first article.

After we had found this cause, we decided to treat POIS by hyposensitization treatment. Injections of diluted toxins is well known in allergy clinics and known as “hyposensitization”. In fact, treatment of POIS follows a similar procedure but instead of a diluted pollen extract we use diluted semen of the man himself.

This treatment consists of regular (weekly) injections in the skin of your own very diluted semen for a few years. By doing this the body looses its immune reaction against the semen. And yes, you have read this well, this treatment lasts a few years. It requires a lot of patience of both the patient and doctor to complete the whole injection program. 

In the second article, we have described two men who were the first to have undergone this treatment. After a few years, this treatment resulted in a significant diminishment of their complaints.

Currently, we also treat other men by hyposensitization but the results of these men are not finalized yet.

In summary, our research has shown that POIS is caused by an immunological reaction to a man’s own semen, that a skinprick test with a man’s own semen confirms this diagnosis, and that hyposensitization treatment diminishes the frequency and intensity of the complaints.

Still, we have a lot of questions about all sort of details. This is normal in science. The results of good research always raise new questions.

In recent years, I have formed a dedicated team of researchers on POIS in the Netherlands. Probably, there is no other research group in the world, that is so much focused on POIS as our team. We continue our research as I would like to find out whether it is possible to cure POIS by medication.

This is not easy, as such research costs a lot of money. Sofar, we have financed our research by our own private money, as there are no institutions that share a serious interest in POIS research. But with the publication of the current key papers on the POIS issue, showing that POIS is a real medical disorder, the odds may rise that financiers become reassured to invest in POIS research.

On the short term, I would like to investigate the characteristics of POIS around the globe since I believe that POIS is a worldwide post-ejaculatory disorder. For that purpose, I would like to send a questionnaire to all of you, and to talk to each of you personally by telephone to discuss your complaints. This will take time and patience from all of us.
 
As most of you are probably interested to read our publication, I propose the following:

If (each of) you will send me an e-mail, stating that you have read this message on the Forum, and that you are willing to fill in a questionnaire, I will send you the copies of both articles by return through email.

At a later date, I will send you the questionnaire which, after having filled in, you should send me back by e-mail.

My e-mail address is : prof.dr.waldinger.pois@gmail.com

You can also look at my website: www.pois-info.com  or www.post-orgasmic-illness-syndrome.com

With best regards,

Prof. Dr. Marcel D. Waldinger

[Finally]

That makes sense.  It explains why sometimes the lymph nodes under my arm would become swollen the first day. 
The treatment sounds expensive and I doubt my insurance will cover it.  And how will you find somebody to do this procedure locally?

[demografx]

Thank you so much, Prof. dr. Waldinger!

[dbfd588]

I read where hyposensitization cn take up to 5 years for treatment. I wonder if that means after 5 or so years that the syndrome will be cured completely or if injections will be a life long chore? Alteast we know now what the cause is.

[dbfd588]

wow yahoo news is going crazy with this new update

[GoingCrazy]

Maybe drinking our own semen was a good idea... haha. I really hope this is the case for all of us.  But I still am confused on how a person can develop this over a period of time, and why symptoms, such as mine, only appear mentally, e.g. I don't get any bodily reactions, no flare ups, sores of anything.  Is there semen flowing through my brain when this happens?  I don't mean to appear as a skeptic or anything it just seems very confusing.

[GoingCrazy]

Still... not a skeptic,  http://www.babycenter.com/404_what-is-a-sperm-allergy-and-how-do-i-know-whether-i-have-one_6150.bc

"A sperm allergy usually has no symptoms (apart from causing fertility problems in some couples). "

maybe we have the "unusual" allergy symptoms?

[CertainlyPOIS]

Maybe drinking our own semen was a good idea... haha. I really hope this is the case for all of us.  But I still am confused on how a person can develop this over a period of time, and why symptoms, such as mine, only appear mentally, e.g. I don't get any bodily reactions, no flare ups, sores of anything.  Is there semen flowing through my brain when this happens?  I don't mean to appear as a skeptic or anything it just seems very confusing.

I do agree how those the brain get connected to all these, i understand the flu reaction but not the fatigue and brain symptoms. 
And how does girlwind figure into all of these women dont make sperm.

[connor]

not sure how much i buy this. at least for my situation, i'm convinced it's more of a nuerological dysfunction that occurs having something to do with nuerotransmitters then an allergy. who knows though

[connor]

wow yahoo news is going crazy with this new update

dont know how much it makes a difference but you can vote up the story so everyone should do that here. or post it to digg reddit, etc.

[POIS-SUFFERER]

Thank you Prof. dr. Waldinger for all your hardwork and dedication to this issue.

I find it interesting and can see how this might explain my condition... but over the last few months things have gotten a bit better for me, I have been taking a lot of D3 and C, and I have dropped the brain fog for sure from my list, all the other items that most have are still there, but the brain fog seems to have lifted :-)

I will email the DR and read the papers and maybe have more to say then.

Thanks again.
PS.

[silverandcol]

Wow, Dr. Waldinger has made some serious progress.  Now the thing that remains is how to make a viable cure that can be used widespread. I hope this can happen soon as 5 years is a long time to suffer.. 

[CertainlyPOIS]

i think dbfd is talking about this.
http://health.yahoo.net/news/s/nm/us_semen_allergy
how did it get out so fast and how do they know so much details.

[demografx]

I agree completely, B_Jim, that it's a great day for us, thank you!

Dr Waldinger said that my success (and 5 others here) with testosterone is not incompatible with his findings.

I think there is much greater hope now. And that doesn't necessarily mean 5 years of waiting. My last 2 years - because of this forum - have been a dramatic, wonderful improvement in my 30-year POIS agony history.

Now, I look forward to even more improvement, and with further research by Prof. dr. Waldinger.

And our road is now paved more smoothly with serious scientific medical papers that we can confidently wave in the faces of all those silly naysayers who say, "it's all in your heads" !