[Quasar]

Quasar, thank you!

Yes, Adderall was effective. Only because of insurance I switched to Ritalin. Equally effective.

I also supplement with caffeine.

I must stress: these are dangerous combinations, especially with TRT which is ALSO a stimulant! Especially for someone like me, a post-cardiac bypass surgery patient!

So, what percentage from that 80% do you think is thanks to Adderall/Ritalin?

Do you take Ritalin for helping in Pois, or other health issues?

Thanks a lot Demo!

[demografx]

Quasar, very hard to say in percentage terms, because I was on ADHD stimulants prior to TRT.

However, I can clearly say that TRT is the lion's share by far in my 80%+ POIS cure for the last 2 and 1/2 years.

In terms of forcing sleep, Benadryl is my added experimental drug of choice. I find that "forcing" or "extra" sleep does wonders in boosting the speed of my POIS recovery.

These are NOT recommendations for others here! Find your own medical path to a POIS cure with a solid, empathetic medical professional(s).

In my case, following the wisdom of this forum in its early years, I did full hormonal bloodtesting with a very competent and empathetic endocrinologist.

I would have never done that if it weren't for this forum!

It still feels like a miracle.

[demografx]

Ryuk,
Welcome!

I can imagine it is almost impossible to go through the 600 pages here;
This community has therefore created a forum to discuss in topics,
for example about the recent niacin solution:
http://poiscenter.com/forums/index.php?topic=174.0
then just click home to see the other topics, it's the best POIS overview we have right now.

mod edit - bold emphasis mine

[GoingCrazy]

I'm just one data point though.

Gee.....and here I thought you were a swell human being.....where did I go wrong??? []

haha demo this where you went wrong... you missed the 1st question !  []  just joking!

lol, she took 50/50

[GoingCrazy]

I take niacin daily without effect:

1) maybe the "spike" of niacin is needed, so my daily intake doesn't work possibly because I have built a tolerance to niacin and now my body doesn't "react", it simply has gotten used to it.

2) I take 325mg aspirin at the same time, which may _counter_  the flush that is necessary for POIS treatment effectiveness.

3) My ongoing and very successful POIS treatment with testosterone + stimulants maybe means that I'm not a good candidate for niacin?

demo, u'd be surprised a lot of stimulants have niacin in them, coffee being the highest.

I've also found it strange that what I think caused POIS for me (coffee) can also relieve it during an episode.

[GoingCrazy]

I've read people dying from that sort of therapy due to shock?  Be careful

Sublingual therapy?

I guess I should of thought twice when I took 100% semen and put it under my tongue.

[GoingCrazy]

I "O'd" seven times in between yesterday night and this morning around 11 am, it is now 12 midnight.  I have about 50% POIS symptoms which usually last for a day.  So far it is pretty much gone.  Should be gone within 12 hours from this point.

This is for everybody taking niacin...

You all mean vitamin B correct?


I definitely feel though, that is, the affect of POIS for me is like something that starts where the orgasm takes place in my head (the upper neck lower brain connection), and feels like something is being forced from there up to my midbrain and into the front of my head.  I'm surprised nobody has POIS like this. [?]

[Willem]

Willem, what exact procedure do you use to prepare the diluted solution of semen?

And do you just hold the solution under your tongue for a few seconds then spit it out?

I will probably try it in the future considering I don't have money to spend on doctor visits and injection treatments.

Willem's Sublingual Immunotherapy Treatment Process

PROCESS:

• Collect fresh semen sample in small glass bowl and let sit at room temp until it completely liquifies (>1hr for me)
• Wrap Al foil over top of glass bowl and freeze
• Treatment schedule is variable.  Always do it at night so I can rest if it induces POIS.  Usually do treatments every other night.
• Anti-histamines: I use anti-histamines to reduce reaction to O, but need to be off of them for 48hrs before treatment in order to gauge how my body is reacting.  I've been off of AHs for over a month now.
• For treatment, remove from freezer, chip off tiny piece (roughly 0.1mL) into another glass bowl, let thaw.  Immediately re-cover and refreeze main sample.
• Fill 1L measuring cup with warm tap water
• Using a 1mL needle-less syringe, draw the chipped-off/thawed sample from the bowl into the syringe.  
• Squirt sample into measuring cup and make sure syringe is evacuated and double check that the semen sample dilutes well (no coagulation)
• Stir, and while stirring, draw a small sample with a dropper
• Clear all saliva from under tongue
• Apply two drops under tongue
• Let sit for at least 5 minutes (no swallowing)
• Swallow.  No food or drink for 30 minutes (so as not to disturb the sore throat measurement)
• The treatment usually gives me a sore throat.  If the sore throat goes away by 10AM (and no POIS etc.), I increase the concentration of the next treatment.  Otherwise I back off of the concentration a bit or keep the concentration constant.

EQUIPMENT:
To get started all you need is a 1mL syringe (see picture below) and a 2L measuring cup with metric units on it.  Once you get into higher concentrations, you will need a graduated cylinder.  Both the 1mL and cylinder came with this dilution kit purchased online.  


PRECAUTION:
This is not medical advice, try at your own risk.  May result in an anaphylactic shock and death or a home remedy cure for POIS, wish me luck.

mod edit - bold red emphasis mine

[GoingCrazy]

Hi Everyone,

Dave and Demo think it's alright to share preliminary results of my sublingual therapy so here goes:

I've been doing the home therapy since May 2011.  I started at 1:50,000 and now am at 1:167.  Around 1:10,000, I started noticing dramatic improvements and have been about the same since then.  Overall POIS is down over 50%.  My mind/energy/motivation/sleep are 80% improved.  My muscles and nerves are about 40% improved.  Recuperation time has gone from 7 days to about 2 days.  I've increased my O frequency from ~1X per week to ~2X per week (trying to get pregnant) and am still feeling pretty good.  Vandemolen has mentioned that major improvements may also come at the 1:70 range so I'm looking forward to that. 

CAVEATS: Since I'm still in the escalation phase I get random side effects from the treatment that I never had from POIS such as: joint pain, intestinal irritation, and pulled muscles.  It also induces a mild, baseline POIS, so maybe I'm being too aggressive, but the treatment itself is not that much fun.  I've been out of town a few weeks and had to take a break from treatments and felt a lot better then, almost normal.  In another 6 weeks or so I should be in the maintenance phase and stop reacting to the treatments.  I'll have a real good idea then of the final outcome.     

Please tell me in 6 weeks if you have POIS anymore.  I am not going to lie about myself but I am a skeptic about this theory.  Please honestly inform me when you are done and orgasm a couple of times, that would be great if it worked. 

[Willem]

I've read people dying from that sort of therapy due to shock?  Be careful

Sublingual therapy?

I guess I should of thought twice when I took 100% semen and put it under my tongue.

Last I read, there were no confirmed deaths attributable to sublingual therapy.  Even when prescribed by a doctor, the treatment is administered at home with no medical supervision because of its safe track record.  My guess is that your mouth needs to be pretty flexible about what it reacts to.  The main reason most people need a doctor for this is to get access to the samples and at the right dilutions.  As long as we are careful about the dilutions, we have plenty of the sample.

All of us are coming into contact with 1:1 semen periodically so wouldn't we all face the risk of anaphylactic shock?

[horizon]

I am not going to lie about myself but I am a skeptic about this theory. 

yeah, im doubtful it works. i did it for awhile.
sure, you get a negative reaction after dabbing a semen mix under the tongue but i suspected it was self-induced.
I decided to do my own double blind test with one bottle 1:2000 semen mix and another bottle pure mineral water.
One gave me a 3/10 negative reaction, the other 0.5/10.
It turned out it was the mineral water that gave me the stronger negative reaction.

It was nacebo (negative placebo.)
ive since stopped mainly because i feel the semen allergy theory is a load of total bollocks.

[prister]

Hey,
Even when i get aroused,
i start getting a headache and i feel numbness and heaviness in my head.
My neck becomes stiff and get a back ache.
i find it difficult to even lift my head and it hurts only on one side and that is on the top right of my head.
i feel memory loss and it is hard to read or remember anything also.
The pain is consistent for several days.
it even continuously hurts in the back of my right eye.
Can i have brain aneurysm or hematoma???
Doctors say it might be a migraine attack but medicines dont help and pain doesnt go for days.!!!
Feels like right side of my brain is rigid or kind of dead..!!!
I too get nocturnal emissions at times.
What problem do i have? (

[Vincent M]

pristor, it definitely sounds like POIS to me.

We've been experimenting with a lot of small home treatments. For instance fenugreek pills taken with a raw garlic clove greatly ease my brainfog and some of my other symptoms. Saw palmetto works very well for me too, but I think it works for me more by reducing inflammation especially in the lower region of my body.

[Quasar]

Hey,
Even when i get aroused,
i start getting a headache and i feel numbness and heaviness in my head.
My neck becomes stiff and get a back ache.
i find it difficult to even lift my head and it hurts only on one side and that is on the top right of my head.
i feel memory loss and it is hard to read or remember anything also.
The pain is consistent for several days.
it even continuously hurts in the back of my right eye.
Can i have brain aneurysm or hematoma???
Doctors say it might be a migraine attack but medicines dont help and pain doesnt go for days.!!!
Feels like right side of my brain is rigid or kind of dead..!!!
I too get nocturnal emissions at times.
What problem do i have? (

Welcome prister!

Yes, it sounds as Pois with a heavy migraine/headache component.

BTW, your right side of your brain is not dead, it's just the scalp. I also get numbness in my scalp after having an "O".

The worse part is that i told doctors i would like to have screened that area of the scalp, but they just limited to do a CT and MRI/MRA of the brain, which obviously was right. In that kind of scans, the scalp -and it's veins and arteries- are NOT easily seen.

[demografx]

I take niacin daily without effect:

1) maybe the "spike" of niacin is needed, so my daily intake doesn't work +possibly because I have built a tolerance to niacin and now my body doesn't "react", it simply has gotten used to it.

2) I take 325mg aspirin at the same time, which may _counter_  the flush that is necessary for POIS treatment effectiveness.

3) My ongoing and very successful POIS treatment with testosterone + stimulants maybe means that I'm not a good candidate for niacin?

demo, u'd be surprised a lot of stimulants have niacin in them, coffee being the highest.

I've also found it strange that what I think caused POIS for me (coffee) can also relieve it during an episode.

GoingCrazy, very interesting!

[demografx]

prister, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:

Our new POIS Forum - architectural genius: "daveman" - for detailed subject-by-subject discussion!
http://www.POISCenter.com/forums/index.php
Our 4-year-old POIS thread here at Naked Science Forum will also always remain open for newcomers, for general unstructured discussion, and historical research of the 10,000+ postings here since 2007.

The Learning Channel's (TLC)  feature TV presentation on POIS, featuring our member here at this forum, "Animus". It was aired on May 22, 2011. Here is a link to the file for that TV documentary, "Desperate Measures", which can be downloaded and played. The segment starts at about 12:20..
http://www.fileserve.com/file/cUtJa9R/TITLE01.mp4

Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

The POIS Information Website is home to the famous POIS Forum Compendium, written by "Pyropeach", and contains theories already discussed here and treatments that have both worked and failed.

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
http://forums.delphiforums.com/POIS/chat

Post Orgasmic Illness Syndrome "POIS": Case report

Authors:
Abdalla M Attia*, Magda H Al-Ziny, Hossam A Yasien
*Corresponding author: Andrology Unit, Minoufiya University, Shibin El Kom, Eygpt

For more info, check out emi_b's  SMF POIS thread:
http://poiscenter.com/forums/index.php?topic=191.0;topicseen


Available Upon Request:

1. and 2. POIS Research Studies, 2011

These 2 papers reveal Dr. Waldinger's POIS autoimmune hypothesis and suggests one possible avenue of treatment.

3. First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

  
4. Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


5. British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


How to get any or all of the above 5 studies: send me or "daveman" a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and we'll send you back the PDF(s).

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around the recipient's name, i.e., "demografx", or "daveman".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the Journal of Sexual Medicine (Dr. Waldinger's study), British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 4 years, our POIS forum has attracted over 200 POIS sufferers worldwide who have posted here, research on an additional 200 sufferers elsewhere on the internet, plus over 1,300,000 page visits. Not bad for a rare malady!



SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: more than 4 years' worth of posts (over  10,000 posts!) from 200+ Forum members, and an additional 200 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.



We started a POIS Medical Research Fund to accelerate our finding a POIS cure! It is explained here in detail:
http://poiscenter.com/forums/index.php?topic=125.0


We've raised nearly $3,000.....with much more $$$ pledged!


And your POIS fund donation is most welcome here:
http://rarediseases.org/about/support/research-donations


Helping the Fund will help YOU to a faster cure for YOUR POIS!!


If you can't contribute now, post your PLEDGE ! Knowledge of your "future funding" intentions will be very uplifting and will affect us all!!


$ Large or small $ !! THANK YOU!!!

[demografx]

All of us are coming into contact with 1:1 semen periodically so wouldn't we all face the risk of anaphylactic shock?

Willem, excellent point!

Wish me luck [with my Sublingual Immunotherapy Treatment Process].

Best wishes, Willem!!

[EDS]

Come on folks!
We really need to get OUR POIS Fund fully funded!

We can get an answer to what really works and what doesn't when we get the professionals at NORD conducting serious scientific research on our behalf.

Let's continue to try things and speculate, but ultimately we need group coordination and trained physicians on our side.

Please pledge... or better yet actually give to OUR fund.

https://rarediseases.org/about/support/research-donations/fg_base_view_p3 [nofollow]

If we don't do this - no one else will!!

[apostate801]

SLIT info

Do you have to create the mixture everyday or will one liter be good til you get desensitized and increase the concentration

[Willem]

SLIT info

Do you have to create the mixture everyday or will one liter be good til you get desensitized and increase the concentration

I personally create the mixture for every application since the particular concentration depends on how I reacted to the previous treatment.  I also try to minimize the freeze/thaw cycles on the semen.