[demografx]

I was considering Vasopressin for overactive bladder, but I didn't like what I heard about its side effects.

[demografx]

Previous forum discussions about vasopressin:
http://www.google.com/search?q=vasopressin+pois+site:http://thenakedscientists.com&ie=UTF-8&oe=UTF-8&hl=en&client=safari

[victor.kons]

Hi Guys,

If we get enough donations/pledges such that we look sure to make the funding, I'll donate another $800

[victor.kons]

As an idea about how to get more donations, I think we should send email to all members of poiscenter.com forum with the information about activity to gather pois research funds. I know that everyone hates bulk emails, but the reason for this email is special and very important and thats why it is reasonable to do this.

What do you think?

[Mr.Cool]

Hi guys, this is my first post here.
I have had these symptoms for maybe 2 years max.
I have researched what the cause is for that time with great interest. My doctors couldn't find out what was wrong except for hypotension. And that I hit a growth spurt. I want to keep my post short so here is a website that could change the lives of many. It might already be put up here and discussed but its worth a try. A lot of you might have this. Please have a look. Thanks and God bless.
  newbielink:http://cure-erectile-dysfunction.org/symptoms-of-sexual-exhaustion [nonactive]

[demografx]

Mr.Cool, welcome to the POIS thread of The Naked Science Forum!  We believe that 2012 is POIS' Breakthrough Year! We hope to launch serious POIS Medical Research! A great time to be here!




**(If you have any technical questions, please feel free to PM (private message) Daveman or me -- go towards the end of this welcome message (after the 5 available research articles are described) for instuctions on how to send PM. We'll be happy to explain!)***


If you haven't already done so, but would like to like to join the new forum,  send "daveman" a PM here at the Naked Science Forum -- "daveman".  He'll reply to you.


Here are some POIS resources which may be helpful to you:

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
Just click HERE first, and then look for "CHAT" button towards top of page, 6th button to your right!


Our new POIS Forum - architectural genius: "daveman" - for detailed subject-by-subject discussion!
http://www.POISCenter.com/forums/index.php
Our 4-year-old POIS thread here at Naked Science Forum will also always remain open for newcomers, for general unstructured discussion, and historical research of the 10,000+ postings here since 2007.

The Learning Channel's (TLC)  feature TV presentation on POIS, featuring our member here at this forum, "Animus". It was aired on May 22, 2011. Here is a link to the YouTube file for the POIS  TV documentary, "Desperate Measures":

Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

The POIS Information Website is home to the famous POIS Forum Compendium, written by "Pyropeach", and contains theories already discussed here and treatments that have both worked and failed.

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

Post Orgasmic Illness Syndrome "POIS": Case report

Authors:
Abdalla M Attia*, Magda H Al-Ziny, Hossam A Yasien
*Corresponding author: Andrology Unit, Minoufiya University, Shibin El Kom, Eygpt

For more info, check out emi_b's  SMF POIS thread:
http://poiscenter.com/forums/index.php?topic=191.0;topicseen


Available Upon Request:

1. and 2. POIS Research Studies, 2011

These 2 papers reveal Dr. Waldinger's POIS autoimmune hypothesis and suggest one possible avenue of treatment.

3. First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

   
4. Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


5. British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


How to get any or all of the above 5 studies: send me or "daveman" a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and we'll send you back the PDF(s).

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

It can be very  helpful to you when dealing with medical professionals to point out the
POIS' official listing, as recognized by the
National Institutes for Health (NIH), Office of Rare Diseases Research:

And in Europe: Orphanet now lists POIS on their website! - Click here!

POIS also appears in credible medical sources such as the Journal of Sexual Medicine (Dr. Waldinger's study), British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 4 years, our POIS forum has attracted over 200 POIS sufferers worldwide who have posted here, research on an additional 200 sufferers elsewhere on the internet, plus our pages have been read nearly 2,000,000 times! Not bad for a rare malady!



SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: more than 4 years' worth of posts (over  10,000 posts!) from 200+ Forum members, and an additional 200 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

[demografx]

As an idea about how to get more donations, I think we should send email to all members of poiscenter.com forum with the information about activity to gather pois research funds. I know that everyone hates bulk emails, but the reason for this email is special and very important and thats why it is reasonable to do this.

What do you think?

Daveman has put in a lot of work to do that, but progress slowed when he took on a major new work commitment. I'll pass this on to him and I'm sure he will reply soon. Thanks again.

[Quasar]

Hey guys, i think i've found something. I know we have already too many theories, but this one makes a lot of sense:

Today on the news they said they have discovered that prostaglandin D2 (PGD2) is a key factor in male baldness.

One of my symptoms of Pois is that after having an O. i lose a lot of hair, and if i don't O's then my hair remains strong and i don't lose it.

Then i went to wikipedia and learned that PGD2 is related to Asthma and inflammation. And you know what? Another symptom of Pois, at least for me, is that it makes my asthma and my breathing efficiency quite worse.

But not only this. PGD2 is also related to the Niacin Flush. In fact, is what it causes it: "Research carried out in 1989[3] found that PGD2 is the primary mediator of vasodilation (the "niacin flush") after ingestion of niacin (nicotinic acid)."

Maybe the Niacin Flush is helping us, because it uses the PGD2 (in a different way than an O.) before having the O., and then the O. is not so harmful.

Does anyone know if exist a drug that inhibits PGD2?

[demografx]

Quasar, I think diclofenac does that.

[demografx]

...only 4 registered in the niacin survey. I twould REALLY like to be able to cross reference some information and see why niacin works for some and not for others!

C'mon everyone, let's help Dave out here!

[Quasar]

Quasar, I think diclofenac does that.

So, if Diclofenac (Voltaren) does that then it would be very easy to try. It is an NSAID (similar to aspirin) , so it is relatively safe.  But i can't try it, because i am allergic to asperin and Nsaids. It would be great if we can research more about it. If someone decides to try it, it would be more effective taken before having sex. But please, always read the information leaflet before.

Thanks

[Habibou]

Hi guys, this is my first post here.
I have had these symptoms for maybe 2 years max.
I have researched what the cause is for that time with great interest. My doctors couldn't find out what was wrong except for hypotension. And that I hit a growth spurt. I want to keep my post short so here is a website that could change the lives of many. It might already be put up here and discussed but its worth a try. A lot of you might have this. Please have a look. Thanks and God bless.
 http://cure-erectile-dysfunction.org/symptoms-of-sexual-exhaustion

Amazing finding (evenf if I heard about it once without any details) !!!
It explains every symptome I have linked to my neurotransmitters deficiency

It should be interesting if the solution works and how we can implement what is written bellow :

The solution is to help your neuro-endocrine function and stabilize your serotonin and GABA nervous modulation on the Fight or Flight responses. You must also recharge your parasympathetic nervous system and boost your prostaglandin E-1 , E-3, oxytocin and Nitric Oxide production for healing.

are you cured right now MR Cool?

[Habibou]

I dont think so?
Find on the website :

Cure-Erectile-Dysfunction.org is an online, media publishing organization. It provides authoritative, in-depth medical information covering many aspects of erectile dysfunction.

dr.Mark Richards, MD

Shawn Davis, Customer Support

Ronald Howard, Site Administrator

[Mr.Cool]

Thank you Habibou for the feedback.
Yes this website has been very helpfull for me personally however while it does explain all the symptoms, one thing that puzzles me is my ejaculation rate. I only O once every two weeks or so? Also I am NOT cured but getting better everyday. I think time, not causing as much stress and taking a lot of vitamins, salt and water will heal me. God willing.
I have a a hypothesis that age of your first O might have something to do with our illness? any other people have thoughts about that? Thanks and God bless.

[Quasar]

Hmmm :/  it looks like dr Lin's text.

Definitely. It may not be him, but the style is very similar. It talks about 1000 neurotransmitters and hormones...It doesn't specify, and the recommendations of this kinds of sites usually are: stop masturbating so much, take more vitamins, neurotransmitters, etc. But i'm sure Pois can't be cured like that.

[Mr.Cool]

@ Quasar I am not familiar with dr Lin's text? and why are you so sure? we are trying to look into POIS in everyway we can. We are all on the same team. Also one symptom I experience is floaters and light sensitivity. Does anyone else experience this? Thanks and God bless.

[demografx]

We are not looking into "every way we can", Mr. Cool. Our approach is medical and scientific. Which is why we chose to be part of Naked SCIENCE forum.

Welcome again.

[demografx]

I also agree with Quasar and B_Jim.

The writing lacks credibility.

[observercenter]

Thank you Habibou for the feedback.
Yes this website has been very helpfull for me personally however while it does explain all the symptoms, one thing that puzzles me is my ejaculation rate. I only O once every two weeks or so? Also I am NOT cured but getting better everyday. I think time, not causing as much stress and taking a lot of vitamins, salt and water will heal me. God willing.
I have a a hypothesis that age of your first O might have something to do with our illness? any other people have thoughts about that? Thanks and God bless.

I have been suffering POIS since 7 years ago. In summer months, i had no stress, good diet, and very few O- I was never cured. Currently i am taking niacin before orgasm on an empty stomach. The result is NO POIS if i ejaculate the next 3-4 hours(maybe more?). I hadnīt need to follow all the advices that are on that page to fix my organism(I am pretty sure that nothing is wrong on me, except my very strong inmune system). I strongly suggest you to test niacin on your body. You could be amazed by the results.  Keep us updated!

[GoingCrazy]

Yeah, that text quoting Lin's words above I would say isn't related to POIS.  It is probably talking about general laziness after orgasm that "normal" people usually have.  We can abstain for as long as we can and the next orgasm you are in full blown POIS if you do not take anything beforehand.  It is some un-natural reaction that will always occur as long as we are stricken with this illness.  I have abstained for about 5 years now and still have POIS, yet my recovery time is significantly shorter, taking about a day now as opposed to a week if I do not take anything before the O.  But the fact that you can abstain and you will be cured I say is not true, I think you can only affect your recovery rate after the "O".

QUASAR, I believe that anti-histamines like claritin have that ability to stop prostaglandins.  I think when histamine is used by the body it creates inflammation which then sends out prostaglandins.  I could be wrong.