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Vaccinia, a pox virus particle.

Triggering the immune system to attack tumours

... rashes, and organ damage.  But if we could trigger our own immune system to target a tumour, then we'd have a way to ... David K. -   What we do is we get the body's own defence mechanism, the immune system, to turn its sights ... healthy tissues get hit too. But if we could trigger our own immune system to target a tumour, then we’d have a way ...

Parasites and Allergies

... bit immunosuppressive, dampen the immune system for their own protection.  In the absence of those parasites and those ... in mice so that parasites were able to expand the body's own mechanism that protects us from allergy. Kat -   So the ... the parasite manipulating this human immune system in its own interest, but at the same time, actually having a ...

Electron micrograph of an adult male Schistosoma parasite worm. The bar (bottom left) represents a magnification of 0.5mm.

Preservation of Parasites

Almost every species has its own unique species of parasite - so with every extinction ... and by learning about parasites, we can learn about our own physiology and anatomy.  We also know that parasites are ... of Natural History Almost every species studied has its own unique species of parasite – so with every extinction ...

Figure 2 - Hypothesized reconstruction of the Trichomonas-like infection of a Tyrannosaurus rex. Parasites have plagued vertebrates for a very, very long time. They have co-evolved with us and our evolutionary ancestors over many millions of years.

The Hygiene Hypothesis, Part 3. Are Parasitic Worms Friend or Foe?

... aggressive or inappropriate responses and damages our own tissues in the process. We also learned how helminths ... getting out of hand and causing excessive damage to our own tissues. Mechanisms for this 'immune regulation' include ... that actively attempt to suppress it, purely to aid their own survival. Now, what happens when many of these infectious ...

HIV viruses in green budding from a lymphocyte

Gene therapy for HIV

... to give high doses of chemotherapy to clear the patient's own cells, to allow the incoming cells that are resistant to ... from a donor. You're saying “can I take a person's own cells or even get donor cells and change them in some way ... immune system can be rebuilt from those cells and their own virus can attack them.” Michael - The idea is to take ...

Breastfeeding an infant

Do babies acquire immunity from breastmilk?

... so-called "passive immunity" while the infant animal's own immune system becomes established. But, we don't believe ... after that time the baby should be able to stand on its own two immunological feet. Unfortunately, although ...

Immune cells

Long covid & the immune system: what's going wrong?

Inflammation is a really strong hint that the patient’s own immune system is a major player in this 'long covid'. ... bad. Clare Bryant, University of Cambridge The patient's own immune system seems to be the major player in long ...

Spies

Infiltrating Immune Intelligence

... sometimes something goes wrong and they present our own antigens, initiating immune responses against ourselves." ... they react to certain diseases to better understand our own responses. We can intercept and suppress the precursors ...

Brain scan

Fighting Brain Tumours with Artificial Antibodies

... do instead? Samuel - What we can do instead is to get your own body to fight the cancer, and the main part of the body ... to subvert the cancer tricking in order to get your own immune system to go ahead and attack the tumour again and ...

Electron micrograph of an adult male Schistosoma parasite worm. The bar (bottom left) represents a magnification of 0.5mm.

The Hygiene Hypothesis Unraveled

... autoimmunity ', where the immune system attacks the body's own tissues, and ' allergy ', where harmless particles from ... much of the former and you get excessive damage of your own tissues (e.g. with autoimmune disease or allergy), too ... Diseases caused by the body's immune system targeting its own tissues 'by mistake', resulting in tissue damage. ...

''Ancylostoma caninum'', a type of hookworm, attached to the intestinal mucosa. Hookworms are blood-sucking nematodes that feed on blood. Heavy infections can cause anaemia due to loss of blood.

The Hygiene Hypothesis Part 2: Will Whipworm Work?

... aggressive or inappropriate responses and damages our own tissues in the process. Reintroducing certain parasitic ...

The cuckoo, perhaps the best known parasite, is reared by foster parents. After it hatches the chick pushes its adoptive brothers and sisters out of the nest.

Alzheimer's Protein Relieves MS Paralysis

... but cuckoo chicks have evolved to push out the host's own eggs in order to gain their foster parents' full ... of safely falling nose-first from heights of 2.7 times its own body length. Lawrence Steinman, Stanford University; ...

Inhaler

When the Immune System Fails

... and non-self, thus resulting in an attack on the body's own tissues as in the case of autoimmunity, or by an ... II Occurs when antibodies bind to antigenson the patient's own cells, marking them for destruction, Autoimmune ...

Protein “Restraining Order” for Gut Bacteria

... us healthy, performing important metabolic roles that our own cells can't.  But we don't fully understand how the ...

Sea urchin larva

A new animal model of immunity

... years of evolution - uses many of the same signals our own human immune system does... Kate - Sea urchins have what ...

Probiotic Drink

Teaching T Cells to Tolerate Friends

... other molecules.  Some of these would interact with our own cells, leading to auto-immune diseases but in the thymus ...

Vaccine injection

Immune systems tackling cancer

... of a free, natural resource available to all of us: our own immune systems. The immune system doesn't usually target ...

this is a picture of a syringe and needle

In-situ cancer vaccine knocks out lymphoma

... cells as a threat, because they are still the body’s own cells and can escape immune surveillance. The new ...

Cervical Intraepithelial Neoplasia CIN2

Cancer and Immunity

... system attack the tumour because they are after all your own cells? Richard -   That's a really puzzling thing about ...

Cancer cells in culture

How do cancer cells survive?

... for the cell itself, so they end up dying of their own mutations. Very, very rarely, you get this perfect storm ...

The Red ribbon is a symbol for solidarity with HIV-positive people and those living with AIDS.

AIDS Awareness Week

... HIV works by entering immune cells and using the cell's own machinery to make copies of itself, damaging the cell in ...

cold sore herpes

DNA editing techniques can combat herpes

... of small pieces of DNA that park themselves alongside our own human DNA inside our cells. This places them beyond the ...

Poison Ivy Plant

Plants Need to Switch Off Intruder Alerts

... can contribute to the immune system attacking the person's own tissues, a condition known as autoimmunity. The same ...

Blueberries

Resensitising bacteria to old agents

... and then you'll get an immune response?  You'll make your own antibodies to your drug. Mike -   Well, that's again a ...

Kidneys - these are actually Lamb kidneys, not human ones, but these will do for illustration purposes...

Regulatory T cells trigger immunity to transplant rejection

... whole field of transplantation has been a victim of its own success and so we just can't keep up with the numbers of ...