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Old woman

Prof David Gems - Healthy ageing

... disease. Cheery stuff. At the UCL Institute of Healthy ageing, researchers are investigating the genetics of ageing, and how understanding the fundamental biological ... biogerontology, and started by asking him what we mean by "ageing". David -   The word 'ageing' is a very slippery term ...

A happy, healthy older man

Ageing and Bioscience at the Babraham Institute

... were brought together recently for conference on Ageing and Bioscience, hosted by the Babraham Institute just ... Partridge and I'm Director of the Institute of Healthy Ageing at UCL.  A very practical problem, I think, is the ... healthy as they get older.  The economic impact of the ageing population on health services is just becoming ...

Does your DNA impact your lifespan?

Do we know which parts of our DNA relate to our ageing, and how much of an effect it has? Georgia Mills spoke ... than for the rest of us. Joao - I became interested in ageing when I was a child. I was quite young and I first ... the internet so I wasn’t even aware that you could study ageing, but I was aware of the biomedical research. I knew we ...

Ageing effect on worm reproduction

... gene, or a gene, which might be linked to this premature ageing phenomenon that you were searching for? L. Rene -   ... regulates the durability of the circuit as the animal is ageing. Chris -   What does Sir-2 do?  How does it work?  And how does it influence this ageing process? L. Rene -   Sir-2 is an enzyme that ...

Insulin crystals

Jennifer Tullett - Ageing & metabolism

... a look at the researchers hunting for the genes behind ageing, and now we're returning to the topic with a closer look at the links between genes, ageing and metabolism - that's how we use food to generate ... at different transcription factors that are involved in ageing.  Transcription factors are proteins that are ...

Old lady from Zacatecas, Mexico

Younger Looking Skin

Meera - Whilst ageing is both a physical and psychological process, when ... companies promise, it's possible to reverse the effects of ageing... Patrick - The skin is the largest organ in our ... purely targeting people that are wanting to reverse their ageing? Patrick - We had about 25 years ago a big ...

Old lady from Zacatecas, Mexico

Younger-looking Skin

Meera - Whilst ageing is both a physical and psychological process, when ... companies promise, it's possible to reverse the effects of ageing. Patrick - The skin is the largest organ in our body. ... purely targeting people that are wanting to reverse their ageing? Patrick - We had about 25 years ago a big ...

Animation of the structure of a section of DNA. The bases lie horizontally between the two spiraling strands.

Damaged DNA

... such as cancer and we believe it can also contribute to ageing. Helen - You touched on the idea that we might be able ... a bet that it would slow down at least some aspects of ageing, maybe not all of them. The problem is that our cells ... of bringing that about then that might actually slow down ageing at a cellular level. Helen - So if we could tease ...

Clock

Could humans live forever?

Some animals appear to be able to reject the processes of ageing completely. Could this ever be the case in humans? ... based in California, which aims to reduce the damage of ageing and allow people to live younger. Aubrey - The body ... of the way the body normally works and, in that sense, ageing in a living organism like you or me is exactly the ...

Mouse on the left recieved the treatment compared to mouse who didn't.

Anti-ageing protein reverses senescence

A drug that reverses the ageing process has been unveiled by scientists in the ... of these senescent cells which are contributing to the ageing process and therefore you could, at the very worst, potentially arrest ageing and maybe even wind the clock back a bit? Peter - ...

Tree rings

Why do we grow old?

Ageing happens to each and every one of us, but what is ... Judy - Of course, we don’t have a clear definition of ageing except to say that it’s a process by which multiple ... parts of the body? Judy - It’s interesting that ageing affects different tissues in different ways, but also ...

Fruit flies

The great fly gender divide

... extended. Chris - If one studies the natural history of ageing in these flies (males versus females) and you look ... we did in parallel.  We started to look at the guts of  ageing males and ageing females and when we started out we expected that we ...

Two people on a bench by the sea

Can gut bugs keep you healthy for longer?

... factor from the bacteria and the worms show accelerated ageing, or their more frail, that molecule coming from those bugs might be involved in the ageing process? Daniel - Correct. Though the molecules that ... a lot of the things that we associate with health versus ageing. Chris - What are those molecules? Daniel - The ...

Regan

Gender divide: why females outlive males

... extended. Chris - If one studies the natural history of ageing in these flies – males versus females and you look ... we did. In parallel, we started to look at the guts of ageing males and ageing females. When we started out, we expected that we ...

Michael Shannack - Fat, old flies

... to our age-old topic, at the UCL Institute of Healthy Ageing. Student Michael Shannack has been studying fruit ... in and this is something that's kind of common in ageing research is to try and stress test the things that ... was Michael Shannack, from the UCL Institute of Healthy Ageing. Michael Shannack, UCL Institute of Healthy Ageing ...

Fluoxetine HCl 20mg Capsules (Prozac)

Nazif Alic - Manipulating metabolism

... topic, with Dr Nazif Alic at the UCL Institute of Healthy Ageing. He's figuring out if tweaking some of the genes ... you actually look at these flies and work out how they're ageing? Nazif -  So, one of the main outputs that we've been ... - That was Nazif Alic from the UCL Institute of Healthy Ageing. Nazif Alic, UCL Institute for Healthy Ageing Tweaking ...

Zombie Mannequins

Do Zombie cells promote arterial disease?

It’s a fact of life that we’re all ageing, all the time. And as we age, an increasing proportion ... explain how this relates to a concept of a whole person ageing? Martin - As we age, a greater proportion of our cells ... functioning of many many organs associated just with ageing. Professor Martin Bennett - Cambridge University As we ...

Brain schematic

Reversing ageing in the brain

... good working order. The good news is that this aspect of ageing it might be reversible. To explain how, Robin Franklin ... duration there's a big problem of how you deal with the ageing phenomenon in the adult stem cell. Chris - And Kevin ... research reveals the same is true for our brain. Reversing ageing in the brain ...

How old am I on the inside?

... and chronological ages. Marija - When we think of ageing, we usually talk about chronological age: the time ... that are working in the field of glycan biology and ageing. We have published over 100 peer reviewed scientific ... Is it all these radio programmes I’m producing are ageing me? Marija - Yeah. I guess this is not really helping ...

Dolly the Sheep with her first born lamb, called Bonnie.

Mythconception: Did Dolly the sheep have arthritis?

... raised about the possible link between cloning and early ageing – and many people became convinced that Dolly’s ... and her lung cancer was caused by a virus – not by early ageing. Having said this, the jury is still out on whether or not there is a link between cloning and early ageing. The DNA of a clone will be older than the DNA of a ...

Dehydrate to survive!

... the animation. It's as though they - they even stop ageing. So, animals will do this and they have a natural ... lifetime and when you dry them, that stops and they stop ageing at that point. When you rehydrate them, they will continue ageing and then they will live out what's left with their ...

Taeniopygia guttata - A male Zebra Finch in Karratha, Pilbara, Western Australia, Australia.

Longevity and Telomeres - Planet Earth Online

... of DNA called telomeres - which are often associated with ageing. Birds are known for their long lives.  Petrels, for ... your research came out of the possible connection to human ageing and it almost being that in this case when it comes to ... DNA called telomeres – which are often associated with ageing. Now, by studying Australian zebra finches, ...

Young rats

Oxytocin boosts confidence and lengthens telomeres

... because it can actually predict longevity and successful ageing; and what we did here, we measured telomere length, ... here we have a really nice correlation between successful ageing and social experiences throughout a lifetime. And I ... can do about having healthy life trajectories, helping our ageing population to do successfully and protect brain health ...

Gene of the month - SIRT1

... many of which are connected to energy production and ageing, as well as stress responses and the body clock. And, ... Alzheimer's, diabetes and cancer.  Scientists studying ageing are particularly interested in SIRT1 as it can be ...

Broken chromosomes

How DNA gets damaged

... with DNA and damage DNA.  Actually, there's a theory of ageing that suggests that it's this chronic accumulation of damage of DNA that causes ageing. Kat -   But obviously, we need oxygen to be alive, ...