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Old woman

Prof David Gems - Healthy ageing

... disease. Cheery stuff. At the UCL Institute of Healthy ageing, researchers are investigating the genetics of ageing, and how understanding the fundamental biological ... biogerontology, and started by asking him what we mean by "ageing". David -   The word 'ageing' is a very slippery term ...

A happy, healthy older man

Ageing and Bioscience at the Babraham Institute

... were brought together recently for conference on Ageing and Bioscience, hosted by the Babraham Institute just ... Partridge and I'm Director of the Institute of Healthy Ageing at UCL.  A very practical problem, I think, is the ... healthy as they get older.  The economic impact of the ageing population on health services is just becoming ...

Ageing effect on worm reproduction

... gene, or a gene, which might be linked to this premature ageing phenomenon that you were searching for? L. Rene -   ... regulates the durability of the circuit as the animal is ageing. Chris -   What does Sir-2 do?  How does it work?  And how does it influence this ageing process? L. Rene -   Sir-2 is an enzyme that ...

Why Senior Moments Are Not Inevitable

... span. It's quite well-known that even with normal healthy ageing, we do seem to see a decline in our cognitive ... memory, attention, etc. - and the Cambridge's Centre for Ageing and Neuroscience or Cam-CAN was setup to try and ... is affected very strongly indeed by our stereotypes of ageing. Ben -   So, if we expect that we are getting ...

Insulin crystals

Jennifer Tullett - Ageing & metabolism

... a look at the researchers hunting for the genes behind ageing, and now we're returning to the topic with a closer look at the links between genes, ageing and metabolism - that's how we use food to generate ... at different transcription factors that are involved in ageing.  Transcription factors are proteins that are ...

Old lady from Zacatecas, Mexico

Younger Looking Skin

Meera - Whilst ageing is both a physical and psychological process, when ... companies promise, it's possible to reverse the effects of ageing... Patrick - The skin is the largest organ in our ... purely targeting people that are wanting to reverse their ageing? Patrick - We had about 25 years ago a big ...

Old lady from Zacatecas, Mexico

Younger-looking Skin

Meera - Whilst ageing is both a physical and psychological process, when ... companies promise, it's possible to reverse the effects of ageing. Patrick - The skin is the largest organ in our body. ... purely targeting people that are wanting to reverse their ageing? Patrick - We had about 25 years ago a big ...

GFP-expressing nerve cells in the mouse cerebral cortex

Protecting Neurons from Age-Related Decline

... developments on your work, today, we're talking about ageing.  What does this nerve degeneration process have to do with ageing? Michael -   So, in answer to one of your earlier ... and in certain types of neurodegenerative disease.  And ageing if you like, is a big new growth area in biomedical ...

Animation of the structure of a section of DNA. The bases lie horizontally between the two spiraling strands.

Damaged DNA

... such as cancer and we believe it can also contribute to ageing. Helen - You touched on the idea that we might be able ... a bet that it would slow down at least some aspects of ageing, maybe not all of them. The problem is that our cells ... of bringing that about then that might actually slow down ageing at a cellular level. Helen - So if we could tease ...

What Determines Female Fertility?

... quality. What people may not realise is that reproductive ageing in females begins when they reach their mid 30s, and ... menopause around age 50. So really, female reproductive ageing is one of the first organ systems in the human body to show signs of overt ageing. Georgia - Do we know why this is? Francesca - My ...

Mouse on the left recieved the treatment compared to mouse who didn't.

Anti-ageing protein reverses senescence

A drug that reverses the ageing process has been unveiled by scientists in the ... of these senescent cells which are contributing to the ageing process and therefore you could, at the very worst, potentially arrest ageing and maybe even wind the clock back a bit? Peter - ...

Fruit flies

The great fly gender divide

... extended. Chris - If one studies the natural history of ageing in these flies (males versus females) and you look ... we did in parallel.  We started to look at the guts of  ageing males and ageing females and when we started out we expected that we ...

Michael Shannack - Fat, old flies

... to our age-old topic, at the UCL Institute of Healthy Ageing. Student Michael Shannack has been studying fruit ... in and this is something that's kind of common in ageing research is to try and stress test the things that ... was Michael Shannack, from the UCL Institute of Healthy Ageing. Michael Shannack, UCL Institute of Healthy Ageing ...

Fluoxetine HCl 20mg Capsules (Prozac)

Nazif Alic - Manipulating metabolism

... topic, with Dr Nazif Alic at the UCL Institute of Healthy Ageing. He's figuring out if tweaking some of the genes ... you actually look at these flies and work out how they're ageing? Nazif -  So, one of the main outputs that we've been ... - That was Nazif Alic from the UCL Institute of Healthy Ageing. Nazif Alic, UCL Institute for Healthy Ageing Tweaking ...

Brain injury

How head trauma leads to dementia

... looked at what their brains looked like compared to normal ageing brains. And what we found in that was that they had a ... in patients who’d had a brain injury than in normal ageing. Chris - So when you say it’s in a wider ... was that tau protein was throughout their brain. In normal ageing it can just be in tiny spots here and there as part of ...

A lovely lady in a face mask.

The science of skincare

... Chris - And why is that? Jane - That’s a natural ageing process but that’s magnified by the effects of the ... to a supermarket or chemist or something and buy and anti-ageing cream or something to make me look a bit younger, how ... can lose that. But the creams that are put forward as anti-ageing creams, there’s a bit of a debate as to how well ...

Zombie Mannequins

Do Zombie cells promote arterial disease?

It’s a fact of life that we’re all ageing, all the time. And as we age, an increasing proportion ... explain how this relates to a concept of a whole person ageing? Martin - As we age, a greater proportion of our cells ... functioning of many many organs associated just with ageing. Professor Martin Bennett - Cambridge University As we ...

Brain schematic

Reversing ageing in the brain

... good working order. The good news is that this aspect of ageing it might be reversible. To explain how, Robin Franklin ... duration there's a big problem of how you deal with the ageing phenomenon in the adult stem cell. Chris - And Kevin ... research reveals the same is true for our brain. Reversing ageing in the brain ...

Blueberries

Mythconception: Do antioxidants really keep you young?

... the University of California, Berkeley, he proposed that ageing is caused by reactive molecules that build up in the ... began to rally around the theory of free radical ageing and that antioxidants such as vitamin C and ... a massive racket. The reason the notion of oxidation and ageing hangs around is because it is perpetuated by people ...

The effects of old age on the human face. Portrait of Elisabetha Drum of Kittsee, Austria. Created by Michael Ströck

Clearing Old Cells Prevents Old Age Diseases

... normal mouse.  So now the phenotypes in this accelerated ageing mouse that display ageing related disorders are sarcopenia, which is basically ... gives us the wrinkled skin.  The third hallmark of ageing was formation of cataracts which is seen in about 25% ...

Young rats

Oxytocin boosts confidence and lengthens telomeres

... because it can actually predict longevity and successful ageing; and what we did here, we measured telomere length, ... here we have a really nice correlation between successful ageing and social experiences throughout a lifetime. And I ... can do about having healthy life trajectories, helping our ageing population to do successfully and protect brain health ...

Broken chromosomes

How DNA gets damaged

... with DNA and damage DNA.  Actually, there's a theory of ageing that suggests that it's this chronic accumulation of damage of DNA that causes ageing. Kat -   But obviously, we need oxygen to be alive, ...

Gene of the month - SIRT1

... many of which are connected to energy production and ageing, as well as stress responses and the body clock. And, ... Alzheimer's, diabetes and cancer.  Scientists studying ageing are particularly interested in SIRT1 as it can be ...

Apollo 17 landing1

Social weight Loss, Youthful plants and Moon Landings

... can live for up to 300 years without showing any signs of ageing. Johan Ehrlén from Stockholm University and ... , to get further insight into the role and importance of ageing. "We could find no evidence of decreased performance ... to lose weight, polymers for probiotics, the never-ageing plant and picturing Moon landings... Social weight ...