[joyrex]

It occurs to me that I have been sitting more recently at nights as I have been reading a book. I have read that simply sitting for long periods can put stress on the prostate area. I suppose even more so if the area is susceptible from prior trauma.  Maybe this is why I have been feeling so lousy this week.

I think considering the amount people spend their time sitting on their backsides, more effort should be put into maintaining a correct sitting posture. It's connected with genital health too; newbielink:http://www.salli.com/default.asp?siteid=en&id=Better_genital_health_for_men_with_better_choices [nonactive]

[kurtosis]

Hi Defsync,

first :31 seconds in and he tells me he once had a normal sex life. Am I the only one that was born this way and from the first orgasm to my last its assaulted my brain eliminating the majority of my intelligence?

No, you are not the only one. I had POIS since my first O too.

Victor

Me too. That's one of the aspects of POIS that's so problematic. You can spend a few years wondering is everyone going through this. The answer is a resounding "NO" of course but it's not the kind of thing most men want to discuss with anybody, including their doctor.

[mat780]

Hi Defsync,

first :31 seconds in and he tells me he once had a normal sex life. Am I the only one that was born this way and from the first orgasm to my last its assaulted my brain eliminating the majority of my intelligence?

No, you are not the only one. I had POIS since my first O too.

Victor

Me too. That's one of the aspects of POIS that's so problematic. You can spend a few years wondering is everyone going through this. The answer is a resounding "NO" of course but it's not the kind of thing most men want to discuss with anybody, including their doctor.

Me too! Although in my puberty years I thought it was normal, later in time, as I’m allergic to several things (dust, pollen, etc) I started to relate it with allergies (because of the similar symptoms).
I remember my allergist telling me it was normal to be tired and relaxed after an O!!! But man, not this way!!!

A few years ago I discovered POIS, and the pieces of my puzzle started to fit.

[CertainlyPOIS]

What is the name of the show and episode from the Learning Channel about POIS?

The Learning Channel's (TLC) feature TV presentation on POIS, featuring our member here at this forum, "Animus". It was aired on May 22, 2011. Here is a link to the YouTube file for the POIS  TV documentary, "Desperate Measures":

first :31 seconds in and he tells me he once had a normal sex life. Am I the only one that was born this way and from the first orgasm to my last its assaulted my brain eliminating the majority of my intelligence?

Oh FYI if you havent watched "Game of Thrones" I oh so highly recommend it. Think Rated-R Lord of the Rings.... epic

the one on hbo, very good is the new season out.

[demografx]

What is the name of the show and episode from the Learning Channel about POIS?

The Learning Channel's (TLC) feature TV presentation on POIS, featuring our member here at this forum, "Animus". It was aired on May 22, 2011. Here is a link to the YouTube file for the POIS  TV documentary, "Desperate Measures":

first :31 seconds in and he tells me he once had a normal sex life. Am I the only one that was born this way and from the first orgasm to my last its assaulted my brain eliminating the majority of my intelligence?

Oh FYI if you havent watched "Game of Thrones" I oh so highly recommend it. Think Rated-R Lord of the Rings.... epic

Defsync, you express very well the rage, anger and immense frustration of POIS !

[Vincent M]

[quote author=badgerstripe
Do users of this forum believe low or high histamine is a cause of POIS? I'm confused. I have always thought high histamine was a problem in allergic reactions.
[/quote]

Many of us including myself believe that POIS is caused by an allergic or auto-immune reaction to some component of our semen. I've found that Claritin and Benadryl, both anti-histamines, relieve the majority of my POIS symptoms when taken about an hour before an orgasm.

[John21 (OP)]

Diuretic Update

So far it seems like diuretics allow me to think clearer, and one herbal specific herbal blend has allowed me to sleep very soundly. I am now considering that this is all to do with the prostate, which fits in nicely with the theory that POIS symptoms are a result of an inflamed prostate.  This week I took a diuretic formula that has Uva Ursi which is great for the urinary tract, and also has Buchu leaf, which is great for the PROSTATE. It makes sense that an irritated prostate would be soothed by removing some water thus reducing the pressure, plus any inherent anti-inflammatory action that the herbs have (Buchu specifically). I'm going to look for a prostate formula that contains Buchu leaf and try that as well.

[Defsync]

the learning channel

so I was the first person asked for this episode. I said no cause my girlfriend was like NOT A CHANCE IN HELL. Ok. Well, we broke up, and now I look at this episode, and /facepalm repeatedly because its not the sperm (testes) its the seminal fluid (prostate).

i.... apologize my friends, for failing to address POIS properly on camera. Im considering calling TLC and asking them if they have another opportunity available.

raping your own brain via nocturnal emissions that you and 99% of the male population cant control, is a more poignant observation of the severity of this condition

[kurtosis]

Have had 2 O's in about 5 weeks. Both times I've felt stinging pain from the seminal fluid. The fatigue and cognitive symptoms seemed to be under control thanks to taking niacin and an amino acid & b vitamin cocktail I've cooked up. Hydrolised whey, glutamine, creatine & a small scoop of piracetam on top. Quite a combination and what I used to use as part of a rowing "stack". It seems extra niacin was the missing ingredient for me and this combo kicks me back into focus and gives me a reserve of energy. But the stinging is odd & I'm wondering if this is down to the niacin.
You're probably thinking "he's taking all that and he's worried about the niacin" but I never noticed the stinging before or, if I did, I've long forgotten about it

[cornelius]

I've updated my post about newbielink:http://poiscenter.com/forums/index.php?topic=226.0 [nonactive], to reflect my current thinking on what caused my case of POIS and what I did to escape the ejaculation->collapse cycle. Follow the link if you're interested.

I now believe that my POIS case was caused by acute depression, and that the Fenugreek and Saw Palmetto either helped with the depression or had a placebo effect -- either way, I saw positive effects from taking them, effects which went away if I missed taking them for a day. It's from Vitacost.com and is all unopened and sealed. I wouldn't sell it on to you guys if it hadn't helped me out.


If you're interested, contact me on the other forum.

I read through your post. To be honest about this, I think you were understandably depressed AND that you had POIS. If POIS is a disease which affects someone as soon as they start having orgasms then you'd probably always remember having POIS but its severity may worsen as you grow older and it takes a greater toll on your nervous system.

I definitely came out of puberty with the idea that an orgasm one day would mean that I would wake up the next in a worse off mental state. Early in college, I mentioned this to friends only to be met with confusion from them. I didn't realise that it was unusual until then.

I'm open to the idea that "the POIS got worse", but it's equally likely that the work I was attempting became harder, and that whatever measure of focus I could bring to bear became less and less equal to the task. As I said in my post - it's impossible to accurately chart the POIS state; it has too many negative mental effects.

Indeed it may indicate that the catch all "ADD" describes illnesses that affect catecholamine levels in a similar manner to POIS. People who first start experiencing ADHD during puberty may actually have POIS and this illness may not be as rare as we believe. Some There's been significant discussion on this group positing that catecholamine depletion could be what's effecting our nervous systems. Every treatment that people are reporting has a benefit seems to raise our levels of dopamine and/or norepinephrine. Strattera will absolutely affect your levels of norepinephrine. If this works for you then that's great and we should all consider it.

You should also bear in mind just how little is understood about normal brain function around orgasm / sexual arousal. It's entirely possible that the catecholamine / histamine / dopamine / norepinephrine levels that you're charting are "perfectly normal" (whatever that is). To play devil's advocate - perhaps the odd test results you're seeing are caused by something completely separate, with POIS only a symptom of that thing.

However, (& I don't intend any offense) ADD is one of the vaguest diagnosis as the disposal of psychiatrists YET the treatment may improve or alleviate POIS symptoms. For example, would you label everybody with "brain fog" as suffering from POIS?

No - the only defining characteristic of POIS is that symptoms have onset with sexual activity, and are reduced thereafter over a period of days. The problem with this is that it's all self-reported, and from patients who admit that they suffer cognitive deficit (most of us?)

I doubt it as it's not yet an approved diagnosis but that's how strattera is being prescribed to kids (mostly young adults) suffering from concentration problems. I'm confident that being prescribed Provigil would improve your focus and concentration issues but that doesn't mean it's a "cure" or that the prescription of it implies any nuanced knowledge of the condition that's causing our neurotransmitter problems.

Post-orgasm mental confusion, loss of short term memory, irritability, exhaustion, inability to get out of bed; these are all symptoms that I had, which lifted when I started dealing with my depression. I realise now that I probably had all of these symptoms on a day-to-day basis, and was completely unaware of how they were affecting me. I only noticed when orgasm made them significantly worse. These are all quite common symptoms of depression, and my Strattera has nothing to do with it.

ADD is rigourously defined in the Diagnostic and Statistical Manual of Mental Disorders; known as DSM-IV.

Therefore, I don't think it's fair for you to suggest that people who are experiencing severe negative symptoms post orgasm are simply deluding themselves when the alternative you're suggesting is a diagnosis that basically says "your brain isn't working right".

Are you accusing me of telling people who report that their 'brains don't work right' post-orgasm that "their brains don't work right post-orgasm"? If so, you're spot on.

My point is that certainly in my case, and perhaps in theirs, that the problem exists without orgasm, which merely acts as a trigger for symptoms. Perhaps they don't experience these symptoms at all when abstaining -- I would have said that of myself at the time -- but perhaps an outside observer would be a better judge of that.

These statements by you below and your ready acceptance of "diagnosis" by "doctors" who never actually tested your neurochemcial levels by Gas chromatography and mass spectrometry, imho, discredit pretty much your entire thesis on a research level.

Are you a neurologist? Humanities' understanding of brain function is far below the ability to perform simple tests to fully understand complex interactions such as orgasm. I'm afraid that there is no such test as one to determine (chemically) whether or not someone is suffering from memory loss or irritability (for example). There are some indicators - such as MRI's of people with Alzheimers, but our understanding is far from complete.

I refer to a diagnosis and doctors without quotes because they have been certified, and are working from the internationally recognised set of diagnostic material.

You have a good charisma

Thanks!

but I dont think your science is too sound. Also the "compendium" for POIS is this forum. Your statement

"regular, intense exercise, these sufferers also"

quotes these sites:
sites.google.com/site/poiswebsite/test.../exercise-and-enhanced-diet
poiscenter.com/forums/index.php?topic=111.60
poiscenter.com/forums/index.php?topic=226.0

None of which would classify as a compendium. Naked Scientists is THE compendium.

The POIS Compendium is a specific document, the section I am referring to is available here:
newbielink:https://sites.google.com/site/poiswebsite/test-page/successful-methods/exercise-and-enhanced-diet [nonactive]

It is a compendium of accumulated observations reported on this forum.

One thing on this forum is you have to be careful how you word things. Our research carries a lot of weight if its scientifically sound.

If you read the thread on the other forum, the credibility of POIS-as-a-condition is far from certain. There is an absolute dearth of data for the 'normal' case, let alone enough to establish anything about how POIS is different.

If you are truly POIS free, that is is awesome.

It certainly is!  []

My experience has caused me to question the idea of POIS as a condition - and to view it more as a set of negative symptoms which predictably and consistently get much worse following sexual activity.
(a set of negative symptoms qualifies as a medical condition)

I had hoped to disprove you, but the definition of 'Medical Condition' is so vague as to be unhelpful. My main point however, that orgasm is not necessarily the cause of the symptoms (even though it is a trigger for their onset) is far from disproven.

I am completely POIS-free
(but then you explain that you are actually not "completely" free. if you have to include an asterisk next to that statement, i wouldnt bother saying it)

I am completely free of post-sexual-activity negative effects.  I just no longer believe that they were caused by a single as-yet-unrecognised new condition. There is insufficient evidence to support such a hypothesis, and more than enough possible and more-plausible alternatives to call that view into question.

first :31 seconds in and he tells me he once had a normal sex life. Am I the only one that was born this way and from the first orgasm to my last its assaulted my brain eliminating the majority of my intelligence?

No, you are not the only one. I had POIS since my first O too.

I believe that I had the symptoms of POIS from my first time as well - but the memory loss and inability to focus made it very hard for me to make the association. I didn't make the association - or that it was unusual - for a very long time (late teens).

[kurtosis]

Cornelius, I'm suggesting that it is irrelevant whether the symptoms of ADHD are rigorously defined when all they say is "displays signs of inattentiveness and forgetfulness" and displays some signs of either hyperactivity or impulse control. That's practically everybody, the only difference is severity.  And by the way, in Europe the criteria for diagnosis are stricter. See Nature Reviews. Neuroscience 9 (12): 957–64. The diagnostic criteria aren't free from controversy - Arch Gen Psychiatry 5 (63): 540–549.

You're insistent that catecholamine depletion could have no effect on depression but this isn't so. See Arch Gen Psychiatry 1999 May; 56(5):395-40 where research shows that the artificial depletion of catecholamines using inhibitors leads to depression in patients that were previously depressed but were considered in remission. This is an interesting result. There's also a misconception that all depression is treated with similar medications but both strattera and Bupropion (that another poster said benefited them) are NRI's rather than SSRI's. Again, this points me towards catecholamine depletion as the cause of the POIS symptoms described by posters.
 
You can't know your depression, post-orgasm physiological experiences and attention problems are not related, nor can you be sure of the causal chain, but you strongly suggested in your previous post that the underlying problem for all of us is ADD and depression. If not, that's what it appeared you're still suggesting in quite a forceful manner may I add. You can't know this so it's just conjecture. It has no more weight than the other conjectures here including my own.

All I said was that the drug you're taking for ADD (which was originally designed as an anti-depressant) could be used to treat POIS if it's a catecholamine depletion disorder. It would have a beneficial effect. But that doesn't mean it's the only possible treatment, nor that with further study the depletion that may occur in POIS could be prevented. Until then, take Strattera. Never suggested you shouldn't. I'd be happy to try it too.

POIS isn't a diagnosis (as you point out) but I've seen compelling similarities in the symptoms described here. Hopefully NORD will raise enough funding to examine it further. That's important as far as I'm concerned. Our POIS symptoms could lead to an ADD diagnosis. Medical professionals may decide POIS is a form of ADD but until then we cannot simply dismiss the possibility that POIS is a separate condition. Especially so as Europeans are less likely to be diagnosed with ADD and therefore less likely to be prescribed Strattera which may improve their symptoms. Accurate, specific and accepted diagnosis is something to aim for as it will hopefully mean that few sufferers of our conditions go untreated. There's nothing to be lost by further investigation by a respected organisation such as NORD.

[GoingCrazy]

Hi Defsync,

first :31 seconds in and he tells me he once had a normal sex life. Am I the only one that was born this way and from the first orgasm to my last its assaulted my brain eliminating the majority of my intelligence?

No, you are not the only one. I had POIS since my first O too.

Victor

I developed it after coffee usage, or maybe it just so happened that I developed POIS as I was drinking coffee.  Both must involve hormones.

I'm pretty sure people must have, but has anybody just gradually developed POIS without introducing a chemical or something different to your body, like coffee for me?  Like have you been able to "O" for years or so and just all of a sudden have POIS occur without doing anything differently?

For me, my POIS is DEFINITELY copable, extending now to just about a day (from about a week a couple of years ago), like I "O'd" this morning and right about now it's just about gone (I forgot to mention the 4 "O's" I had last night [O8)]).  Lately I've been taking two caplets of tylenol extra strength and they seem to calm me down and alleviate POIS.  They have been helping me sleep.

It feels that, post orgasm, my brain is being force-fed hormones that it doesn't want, or has already had enough of.  Like it is being "squeezed" in from the rear brain/neck region, gradually being squeezed like a tube to the front area of my brain, than as this ends my brain lingers with headaches of exhaustion particularly in my rear-brain.  It would be strange if this was a normal bodily reaction to sex, but if so, how can the effects be so great on us?

I understand that the 5 "O's" I had definitely might be overdoing it.  Well obviously, to a person with these symptoms post orgasm.  But if I abstain for too long I start getting angry, more angry than I am with pois, but actual anger, not like migraine hormonal imbalance anger etc. from pois, but I start looking at people differently, or I think too instinctually and I think people notice.  Call it sexual frustration.  It's weird that some of my best days are when I'm in POIS, I feel people trying to relate to me more, but yet again this is in crappy mood pois time.  Maybe if I just O once instead of 5 times...Once a week might be my new motto. []

[Stef]

Defsync --

It's sad that you cannot wholeheartedly support your comrade in his willingness to have gone public via the TLC program.

You've attempted to diminish someone who had the personal fortitude that you, yourself, did not have when the opportunity was apparently presented to you.

The TLC channel will not be interested in another POIS story. They've covered the topic already, thanks to Animus and his courage!!

As an aside -- the TLC channel and its producers/directors edit their shows to THEIR liking.  NORD has worked with them closely on several episodes (we had nothing to do with the POIS episode -- I wish that I could say we did!). We know that they write their shows with tact and compassion, and provide only as much scientific information as they feel the general public will want. Like all TV shows -- they present what they think will appeal to the largest audience.

Please -- everyone -- think about how your comments might make another person feel.  It's difficult with all the frustration and misery that POIS causes -- but this is a support group -- you all need to boost each other up, not tear each other down.

If a comment generates more heat than light -- then it's not the right comment.

the learning channel

so I was the first person asked for this episode. I said no cause my girlfriend was like NOT A CHANCE IN HELL. Ok. Well, we broke up, and now I look at this episode, and /facepalm repeatedly because its not the sperm (testes) its the seminal fluid (prostate).

i.... apologize my friends, for failing to address POIS properly on camera. Im considering calling TLC and asking them if they have another opportunity available.

raping your own brain via nocturnal emissions that you and 99% of the male population cant control, is a more poignant observation of the severity of this condition

[GoingCrazy]

Update:
I'm having interesting results from experimenting with herbal diuretics. I switched from diuretic foods to supplements as it is easier. It is having a profound effect on my sleep. I have had severe insomnia for 10-15 years (I forget when it started). On the diuretics I still wake at night but I am able to get back to sleep and seem to sleep very deeply. It actually feels Iike I'm getting TOO much sleep. This is quite a development for me, I'm thrilled. Herbal diuretics seem fairly safe as long as I don't go way above the recommended doses, and keep my potassium levels up. Presently I have two types: dandelion tincture, and a herbal diuretic blend with Uva Ursi and Buchu leaf. For anyone who is skeptical that something as common as dandelion could have such a profound effect I can assure you that it actually works. The only side effects have been facial twitching and a little dizziness.  So, what is going on and could this have to do with POIS? I don't have a clue, anyone know how this might make sense? My original reason to try it was the notion that increased intercranial pressure might be causing my pulatie tinnitus.  I suppose that is still my best guess, that "subclinical" increased cerebrospinal fluid pressure is being relieved somewhat by the diuretics. This type of problem can also cause double vision, which I also have.

That's interesting and am glad its working for you.  When I think about pois I think about no refreshing sleep whatsoever and a bad mood.  I've always thought about that maybe if I could figure out the "sleep" thing that maybe I could cure my pois and the bad mood.  I too wake up several times a night.  As I've said before I am taking two tablets of tylenol extra strength (weird because tylenol has never really worked for me but maybe its the two pills?) to help me fall asleep.  Again, I've also stated before that the days that i do have really refreshing sleep and sleep all night (only occurs a few nights a year if even that many), the next day I feel phenomenally good without pois.

Please update on your use with these diuretics as I might give it a try, I'm looking for something to help calm me down and help me sleep..

Thanks

Diuretic Update

So far it seems like diuretics allow me to think clearer, and one herbal specific herbal blend has allowed me to sleep very soundly. I am now considering that this is all to do with the prostate, which fits in nicely with the theory that POIS symptoms are a result of an inflamed prostate.  This week I took a diuretic formula that has Uva Ursi which is great for the urinary tract, and also has Buchu leaf, which is great for the PROSTATE. It makes sense that an irritated prostate would be soothed by removing some water thus reducing the pressure, plus any inherent anti-inflammatory action that the herbs have (Buchu specifically). I'm going to look for a prostate formula that contains Buchu leaf and try that as well.

Can you tell me what that one specific herbal blend to help you sleep is?  and where I can get it?

Thanks again 

[John21 (OP)]

Update:
I'm having interesting results from experimenting with herbal diuretics. I switched from diuretic foods to supplements as it is easier. It is having a profound effect on my sleep. I have had severe insomnia for 10-15 years (I forget when it started). On the diuretics I still wake at night but I am able to get back to sleep and seem to sleep very deeply. It actually feels Iike I'm getting TOO much sleep. This is quite a development for me, I'm thrilled. Herbal diuretics seem fairly safe as long as I don't go way above the recommended doses, and keep my potassium levels up. Presently I have two types: dandelion tincture, and a herbal diuretic blend with Uva Ursi and Buchu leaf. For anyone who is skeptical that something as common as dandelion could have such a profound effect I can assure you that it actually works. The only side effects have been facial twitching and a little dizziness.  So, what is going on and could this have to do with POIS? I don't have a clue, anyone know how this might make sense? My original reason to try it was the notion that increased intercranial pressure might be causing my pulatie tinnitus.  I suppose that is still my best guess, that "subclinical" increased cerebrospinal fluid pressure is being relieved somewhat by the diuretics. This type of problem can also cause double vision, which I also have.

That's interesting and am glad its working for you.  When I think about pois I think about no refreshing sleep whatsoever and a bad mood.  I've always thought about that maybe if I could figure out the "sleep" thing that maybe I could cure my pois and the bad mood.  I too wake up several times a night.  As I've said before I am taking two tablets of tylenol extra strength (weird because tylenol has never really worked for me but maybe its the two pills?) to help me fall asleep.  Again, I've also stated before that the days that i do have really refreshing sleep and sleep all night (only occurs a few nights a year if even that many), the next day I feel phenomenally good without pois.

Please update on your use with these diuretics as I might give it a try, I'm looking for something to help calm me down and help me sleep..

Thanks

Diuretic Update

So far it seems like diuretics allow me to think clearer, and one herbal specific herbal blend has allowed me to sleep very soundly. I am now considering that this is all to do with the prostate, which fits in nicely with the theory that POIS symptoms are a result of an inflamed prostate.  This week I took a diuretic formula that has Uva Ursi which is great for the urinary tract, and also has Buchu leaf, which is great for the PROSTATE. It makes sense that an irritated prostate would be soothed by removing some water thus reducing the pressure, plus any inherent anti-inflammatory action that the herbs have (Buchu specifically). I'm going to look for a prostate formula that contains Buchu leaf and try that as well.

Can you tell me what that one specific herbal blend to help you sleep is?  and where I can get it?

Thanks again 

It seems to be a common combination that you will find in herbal diuretics, sometimes with other herbs like cornsilk or dandelion. The one I have is called Herbal Diuretic by Jamieson. Most pharmacies should have one or two types of such products on their shelves. If you want to read the ingredients bring your magnifing glass, lol. I am not having the sleep success that I initially had with this product, and I am fearing that it was only the initial reaction to it that helped me so much, not sure at this point.  For sure these herbal diuretics allow me to think clearer, that has not changed. But the incredible sleep that I got from that specific blend is not performing any more. My thinking is that it was the muscle relaxant properties of one of the herbs that caused the sleep. That would make sense because the only time that I have had a decent sleep in the last 10-15 years is when I am sick with a cold, then I sleep like a baby because I am run down and relaxed.

WARNING:  Uva Ursi can be toxic. I know anything, even water can be toxic but some sources claim that it should only be taken for a short duration.  This source says no longer than 5 days:

http://www.umm.edu/altmed/articles/uva-ursi-000278.htm

My diuretic bottle labels do not contain such warnings so I presume it is a dose dependent warning, or maybe this listed source is very cautious.

[questforlife]

Hi Everyone, its been a long time since I posted on here and I have been reading through all of the posts.

Please can someone tell me as I have been unable to find this. Has anyone constructed a poll or questionnaire for us members to discover if there is a common pattern to:
mental/physical symptoms
chemical levels in the body for tests
supplements/medication that have showed negative and positive effect

Is there any test the moderators believe we should have done - hair elemental analysis?  If we are all anxious for the answers to this, perhaps we should be all getting the same tests done instead of spending money guessing on supplements etc.

There seems to be some people drawing some conclusions, ie low histamine, low zinc levels etc.

Apologies if this has already done but if it has been its not easy to find, perhaps something like this could have an easy access on ever POIS page?  Its very confusing going through peoples notes working out what might be relevant to us all.  I like all of you, im sure want to draw to conclusions, and for me the current format makes this difficult.

I personally have had many tests and am willing to share information however there is also the issue of sharing information that is not relevant  and causing more confusion.

It appears this issue is complex (not saying that the solution has to be) and that if we are not responding to results/factual info then we could be all guessing for a very long time wasting time and money with theories and supplements.

[daveman]

Very good job Vincent Marcus. Pois may cause a rush of histamines, then a depletion.

Claritin and Benardyl are H1 anti-histamine class.

H1 receptors tend to produce the symptoms already listed and activate allergic reactions.

H2 receptors tend to act as negative feedback receptors and turn the allergic reaction off. They also activate the acid-producing, parietal cells of the stomach lining.

Histamine dilates blood vessels and acts with prostaglandins, PGE2 and PGI2, to produce the early swelling, redness and heat of an inflammatory response.

Claririn seems very safe and popular.
Scientific name : Loratadine
Dose : 10 mg a day
Duration of action : 24 hours
Onset : 1-2 hours    

Great answer to a complex question! One would think that if it's an alegrgic reaction, we would need to "kill" the histamines (anti-histamines), but the depletion that anti-histamines can cause has only partial effect, and I think the following is why.

Its seems there could be a more complex situation. First of all, the human male orgasm generates a histamine rush that I would tend to say goes beyond the reach of anti-histamines. If the system normally generates them, it's because they are required. Reducing that reaction with anti-histamines would have a negative effect, and furthermore, most of our tests of anti-histamines have been "after the fact", after the histamaine rush of the orgasm.

So, something like niacin, is like "food" for the system that genreates histamines, and is the same "food" that is definitely required to produce dopamine and serotonine. During the histamine rush and later during any potential auto-immune reaction, all "food" is consumed to make the required histamines. So no "food" remains to make dopamine and serotinine. Geez, why do we feel bad?

So the histamine pump before "O" is tremendously important.

So why don't we have enough capacity to provide this "food" ourselves??

GOOD QUESTION. Who might know? Who, that is, with experience and title and facilities to make ALL of us warm and fuzzy?

[daveman]

the learning channel

so I was the first person asked for this episode. I said no cause my girlfriend was like NOT A CHANCE IN HELL. Ok. Well, we broke up, and now I look at this episode, and /facepalm repeatedly because its not the sperm (testes) its the seminal fluid (prostate).

i.... apologize my friends, for failing to address POIS properly on camera. Im considering calling TLC and asking them if they have another opportunity available.

raping your own brain via nocturnal emissions that you and 99% of the male population cant control, is a more poignant observation of the severity of this condition

You know, any one of us can go on one of these shows and say what we THINK is going on, and we'd probably just be showing our ignorance.

We've all got our theories, God only knows. And right now, he's the only one who knows. What we need are facts. $30.000 more of facts. Research is ALL that we have.

These shows are exposure. They help us find people with bucks to get us that very needed research.

The best that we can do is exactly what has been done. Show what this monster is and what it can lead us to, how it screws up our lives.

There are good people out there with both cash and hearts!!

[daveman]

I'd like to comment on Cornelius's post.

I would venture based on my experience and I suspect many like your own, hat Cornelius has a particular situation which probably reflects in some of us here.

We have had a very hard time with confusion between POIS and other illnesses like ADD, depression, CFS, Sexual Exhaustion etc. etc. This confusion is accentuated by the fact that POIS not only interacts with the aforementioned illnesses, but can outright create symptoms similar to them.

I know there are a number of us who very likely suffer from one or more of these illnesses in and of themselves, or have developed one of them as a result of a lifetime of POIS.

We each have to evaluate what our own situation might be. I can unequivocally state that my situation is NOT like Cornelius's, however, it may well serve some of you to check and see if there could be some other factor involved in your POIS situation.

Perhaps the strongest point to consider is whether or not you can ever find POIS free moments, this of course after a respectable time of abstenance. Obviously if you are having orgasms once every two days, you cannot answer this question. I would imagine that at least 4 weeks of abstenance would be required to properly identify whether your symptoms diminish or not. Some may require more, some less.

BUT, it is certain that Cornelius is not speaking for ALL POIS sufferes, however, the whole area of depression and ADD is a headache for POIS.

Again, RESEARCH, RESEARCH is our only answer. We can ask, and doubt and debate and wonder until we're blue in the face!!

[B_Daniel]

So I've had pois since I was 12.  I'm 28 now, and over the last 16 years, I don't think there were many days that I was out of POIS.  On days now when I'm out of it, I'm in a much better mood, I feel much better, I have less anxiety.  And I can think a little better.  But I can't think perfectly.

Yesterday in class we had to give presentations.  There was no way I could have gotten up, without notes, and spoken for 5 minutes like almost everybody else did.  I had to pass my part off to someone on my team.

Do ya'll think that pois could have given me brainfog for so long that my brain doesn't know how to make the connections properly anymore.  Maybe it will take years out of it for me to really sharpen my thinking again.  

Is this the case with anyone else?  Does anyone have any thoughts on this?