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Quote from: Quasar on 09/08/2011 22:06:25Demografx,What you say makes sense to me. I believe POIS makes some kind of change to the circulatory system. One of my main symptoms is that after O, i feel a change in my scalp, heart, and abdominal veins. I don't know if POIS makes them to contract or dilate. It feels like a migraine to the whole body. Also, under POIS, i loose my sexual potency, and become some kind of impotent. So, it makes a lot of sense that Levitra helps. It would be very nice to know if POIS either makes our blood vessels to dilatee or contract. Then we could think of an strategy. I mean, maybe aborting that dilation, or that contraction in the first place. If we take a look at this page: http://www.relieve-migraine-headache.com/abdominal-migraine.htmlwe can see beta-blockers are proposed for abdominal migraines. Was just reading about Niacin flushes - seems to be related to what you suggest and hence reversal of effect?"Niacin causes flushing by dilating (expanding) the blood vessels on the surface of the skin. Although this side effect of niacin is harmless, it is often severe enough for people to stop taking niacin."
Demografx,What you say makes sense to me. I believe POIS makes some kind of change to the circulatory system. One of my main symptoms is that after O, i feel a change in my scalp, heart, and abdominal veins. I don't know if POIS makes them to contract or dilate. It feels like a migraine to the whole body. Also, under POIS, i loose my sexual potency, and become some kind of impotent. So, it makes a lot of sense that Levitra helps. It would be very nice to know if POIS either makes our blood vessels to dilatee or contract. Then we could think of an strategy. I mean, maybe aborting that dilation, or that contraction in the first place. If we take a look at this page: http://www.relieve-migraine-headache.com/abdominal-migraine.htmlwe can see beta-blockers are proposed for abdominal migraines.
Hello everyone,A friend of mine has been suffering on a daily basis from physical symptoms identical to those of POIS, for about ten years already. He was diagnozed with Fibromyalgia (which has no treatment as far as I know. At least he didn't find one).Yesterday he told me that he has been sufferring from the symptoms (I guess more than usual, he didn't elaborate) also after ejaculating, and that he believes he has POIS.Through out the years he has had lots of tests and turned to lots of specialists who took his money and didn't really help him. When he discovered that POIS existed and that he was not alone or crazy, he turned to his doctors who dismissed his claims explaining that its all psychological and that he should see a psychologist (which he does!).From what I read untill now, I strongly believe that there is a connection between the POIS and the Fibromyalgia.My question is that (and thank you for reading so far! []):Does any of you suffer from those symptoms (especially physical, but not only) also without having ejaculated? even for only a period?TNX a lot!Timri.
Hi,I'm very happy some of you have had success with Niacin. Definitely I'm going to try it myself soon. But as i'm also interested in a long-term cure, i still have some questions about the allergy theory. Basically i'd like to know if any of you tried the standard method some clinics offer in case of semen allergy:"At the University of Cincinnati, we treat semen allergy by desensitizing women to their sexual partner's semen with injections similar to regular allergy shots. We take ejaculate from the woman's sexual partner and separate the large and small proteins. The woman is skin tested to these proteins to determine which ones she react to. She is then desensitized over several hours to the proteins she reacted to in the skin test. The injections are given every 10 to 15 minutes at increasing concentrations. After the desensitization has been completed, ejaculate is instilled into the woman's vagina. If she has no symptoms, then the treatment has been successful."It does not sound very different to Dr. Waldinger methods. And it can be done in a lot of clinics...
I'm in POIS too, so I could only come up with this idea for a T-shirt:If you're curious about the above, see the discussion which starts with B_Daniel's post at:http://poiscenter.com/forums/index.php?topic=125.msg2156#msg2156 []
Quote from: FinalPanic on 09/08/2011 22:46:55Quote from: Quasar on 09/08/2011 22:06:25Demografx,What you say makes sense to me. I believe POIS makes some kind of change to the circulatory system. One of my main symptoms is that after O, i feel a change in my scalp, heart, and abdominal veins. I don't know if POIS makes them to contract or dilate. It feels like a migraine to the whole body. Also, under POIS, i loose my sexual potency, and become some kind of impotent. So, it makes a lot of sense that Levitra helps. It would be very nice to know if POIS either makes our blood vessels to dilatee or contract. Then we could think of an strategy. I mean, maybe aborting that dilation, or that contraction in the first place. If we take a look at this page: http://www.relieve-migraine-headache.com/abdominal-migraine.htmlwe can see beta-blockers are proposed for abdominal migraines. Was just reading about Niacin flushes - seems to be related to what you suggest and hence reversal of effect?"Niacin causes flushing by dilating (expanding) the blood vessels on the surface of the skin. Although this side effect of niacin is harmless, it is often severe enough for people to stop taking niacin."Absolutely. Niacin flush seems to dilate blood vessels, so taken before orgasm, it could abort the vasocongestion an orgasm causes: Before having an O, our blood vessels are contracted because of adrenaline, etc. When we have the O, we also have sudden local spikes in blood pressure in different areas of the body. After having the O, sometimes we get a facial flush because of histamine/serotonin, and blood vessels dilate.¿What if our blood vessels are not enough elastic (or too much contracted) and the local spikes in blood are too high? Then, our blood vessels dilate too much. They overreact! This is how i think the Levitra, and the Niacin flush work:They dilate blood vessels before having an O, so the spike in blood pressure is less intense, and blood vessels don't have to overreact, they don't have to over-dilate.I think a dilation from Levitra / Niacin flush is very different from a dilation from a sudden blood pressure spike coming from contracted blood vessels (orgasm):In the first case, we have a dilation from nitric oxide and niacin. In the second case, we have a dilation from an unhealthy spike, coming from blood too low in oxygen, and the key ingredients are histamine and serotonin, which are more aggresive and more prone to migraines. So, to sum up, it makes a lot of sense that Niacin an Levitra are somehow working. We could think of more vasodilators. Not all of them are going to work, or course.I can think of beta blockers. But they act more like preventing contraction. They are not exactly vasodilators. So, depending on the beta blocker, they could be more or less effective to us.Take a look at this:"The first generation of beta-blockers were non-selective, meaning that they blocked both beta-1 (β1) and beta-1 (β2) adrenoceptors. Second generation beta-blockers are more cardioselective in that they are relatively selective for β1 adrenoceptors. Note that this relative selectivity can be lost at higher drug doses. Finally, the third generation beta-blockers are drugs that also possess vasodilator actions through blockade of vascular alpha-adrenoceptors."But remember: beta blockers don't work instantly, they need some days. Some examples of 3rd generation beta blockers: Carvedilol, Bisoprolol, Nebivolol, Metoprolol. Look at this: "Nebivolol, a new third-generation ß1-selective blocker, which in addition to ß1-adrenergic receptor inhibition also increases endothelial nitric oxide (NO) release, thereby inducing peripheral vasodilatation"And also this one: "Carvedilol:The use of beta blockers for migraine prevention is not new. The evidence for the use of this pharmacologic class was well established with propranolol, timolol, atenolol, and nadolol. The use of novel beta blockers, such as carvedilol, for the prophylactic treatment of migraine is a new concept because it offers additional alpha-1 blocking and antioxidant properties. This nonselective alpha-1 and beta-1 antagonist reduces blood pressure by reducing peripheral vascular resistance with no alteration of heart frequency or cardiac debit.[41] The results are a very favorable adverse event profile, which may represent an appeal in migraine prevention because traditional beta blockers have limiting side effects. Of the 68 patients who completed the study, 40 (59%) experienced a 50% reduction in monthly migraine attack frequency at the third month of treatment."Also, Angiotensin II receptor antagonists are very interesting: they block the activation of angiotensin II AT1 receptors. Blockade of AT1 receptors directly causes vasodilation, reduces secretion of vasopressin, and reduces production and secretion of aldosterone, amongst other actions. The combined effect reduces blood pressure.Here they compare a 3rd generation beta blocker with an Angiotensin II receptor antagonist:http://www.docguide.com/sexual-activity-hypertensive-men-treated-valsartan-or-carvedilol-crossover-studyErectyle disfunction is a complain with betablockers, but it is not with Valsartan (angiotensin II receptor antagonist).Take a look at this: Angiotensin II is a natural substance in your body that affects your cardiovascular system in many ways, such as by narrowing your blood vessels. This narrowing can increase your blood pressure and force your heart to work harder Now that i think about it....i remember that after having an O, one of the symptoms is that i can feel my heart pumping harder. The pumping is quite more strong and noticeable. Another alternative are Alpha blockers: "They relax certain muscles and help small blood vessels remain open. They work by keeping the hormone norepinephrine (noradrenaline) from tightening the muscles in the walls of smaller arteries and veins. Blocking that effect causes the vessels to remain open and relaxed. This improves blood flow and lowers blood pressure.Because alpha blockers also relax other muscles throughout the body, these medications can help improve urine flow in older men with prostate problems."Another alternative i can think of as now is nitric oxide supplements (NO2) taken an hour before having an O. They use to sell them for boybuilding. Finally, another one interesting could be indomethacin (it is used to treat sexual headaches), but i think someone in the forum tried it without too much success.
Very interesting! I am getting major POIS relief from testosterone.And I also take metropolol, Levitra, and Niaspan (extended release Niacin).I hope that I'm not over-dilating!!!
Quote from: TIMRIL on 09/08/2011 15:57:57Hello everyone,A friend of mine has been suffering on a daily basis from physical symptoms identical to those of POIS, for about ten years already. He was diagnozed with Fibromyalgia (which has no treatment as far as I know. At least he didn't find one).Yesterday he told me that he has been sufferring from the symptoms (I guess more than usual, he didn't elaborate) also after ejaculating, and that he believes he has POIS.Through out the years he has had lots of tests and turned to lots of specialists who took his money and didn't really help him. When he discovered that POIS existed and that he was not alone or crazy, he turned to his doctors who dismissed his claims explaining that its all psychological and that he should see a psychologist (which he does!).From what I read untill now, I strongly believe that there is a connection between the POIS and the Fibromyalgia.My question is that (and thank you for reading so far! []):Does any of you suffer from those symptoms (especially physical, but not only) also without having ejaculated? even for only a period?TNX a lot!Timri.TIMRIL, there are over 300 posts here addressing fibromyalgia.Maybe they can help: newbielink:http://www.google.com/#sclient=psy&hl=en&source=hp&q=fibromyalgia+POIS+site:http%3A%2F%2Fthenakedscientists.com&aq=f&aqi=&aql=&oq=&pbx=1&bav=on.2,or.r_gc.r_pw.&fp=64480e3e283e02ba&biw=1045&bih=471 [nonactive]
I had quite a carefully thought out post about a POIS theory, asking for comments, and it seems to have been buried very quickly by intro posts, etc., and forgotten. And before that I had had asked a question about niacinamide and it was also ignored. This sort of thing seems to be happening lately as the number of new posters has been increasing, and the welcome posts have been getting longer, etc. To help with the conversation in this thread, I suggest just linking to the full welcome post. For example, the new welcome could be:"Welcome <name>,Please see this link for a full introduction to this thread:http://www.thenakedscientists.com/forum/index.php?topic=6576.msg364636#msg364636We look forward to your posts!"And we could use tinyurl to make the url more manageable. What do you think Demo (and others)?
Quote from: Counterpoints on 10/08/2011 01:03:25I had quite a carefully thought out post about a POIS theory, asking for comments, and it seems to have been buried very quickly by intro posts, etc., and forgotten. And before that I had had asked a question about niacinamide and it was also ignored. This sort of thing seems to be happening lately as the number of new posters has been increasing, and the welcome posts have been getting longer, etc. To help with the conversation in this thread, I suggest just linking to the full welcome post. For example, the new welcome could be:"Welcome <name>,Please see this link for a full introduction to this thread:http://www.thenakedscientists.com/forum/index.php?topic=6576.msg364636#msg364636We look forward to your posts!"And we could use tinyurl to make the url more manageable. What do you think Demo (and others)?Sounds like a good idea to me. By the way the reason I personally didn't respond to your post about sex/porn addiction is because this topic was recently discussed on the other forum and I feel it is sort of a dead end theory at least for me. Besides I seriously doubt those of us who only have an orgasm once a week are addicted to porn or sex. But anyway I've already put all my thoughts on that topic into the other forum.
this supports the allergy theory of niacin. it uses up the histamine necessary to cause allergic reaction from orgasm.
Niacin, taken orally as nicotinic acid, can produce redness, warmth, and itching over areas of the skin; this "niacin flush" usually occurs when doses of 50mg or more are taken and is a result of the release of histamine by the cells, which causes vasodilation. This reaction is harmless; it may even be helpful by enhancing blood flow to the "flushed" areas, and it lasts only 10-20 minutes. When these larger doses of niacin are taken regularly, this reaction no longer occurs because stores of histamine are reduced.
Quote from: Counterpoints on 10/08/2011 01:03:25I had quite a carefully thought out post about a POIS theory, asking for comments, and it seems to have been buried very quickly by intro posts, etc., and forgotten. And before that I had had asked a question about niacinamide and it was also ignored. This sort of thing seems to be happening lately as the number of new posters has been increasing, and the welcome posts have been getting longer, etc. To help with the conversation in this thread, I suggest just linking to the full welcome post. For example, the new welcome could be:"Welcome <name>,Please see this link for a full introduction to this thread:http://www.thenakedscientists.com/forum/index.php?topic=6576.msg364636#msg364636We look forward to your posts!"And we could use tinyurl to make the url more manageable. What do you think Demo (and others)?Sounds like a good idea to me.
By the way the reason I personally didn't respond to your post about sex/porn addiction is because this topic was recently discussed on the other forum...
Besides I seriously doubt those of us who only have an orgasm once a week are addicted to porn or sex. But anyway I've already put all my thoughts on that topic into the other forum.
So, it may be that it is OK to take niacin regularly--that is, even if you build up tolerance so that it no longer causes a flush, it might still be able to prevent POIS because it is still 'using up' the histamine.
Quote from: demografx on 09/08/2011 06:37:55I'm in POIS too, so I could only come up with this idea for a T-shirt:If you're curious about the above, see the discussion which starts with B_Daniel's post at:http://poiscenter.com/forums/index.php?topic=125.msg2156#msg2156 []I got a couple of quotes for 100 T-Shirts [ Invalid Attachment ] This was the most expensive. Donors could look at buying this $7.22 T-Shirt for a minimum of $100, proceeds going to NORD, something like that.