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Hey Lars, I noticed that already and i believe serotonin is involved in POIS ; i've taken SSRI for two years with at first a total suppression of my symptoms.That being said, I dont' think that the mechanism is that simple ; the niacin you ingest to produce serotonin after 30 minutes, it should have to inhibitory/protective effect somehow. My experience with niacin has never been conclusive but I need to give other tentatives ; 5HTP helped me.
Poisers may have a sudden fall in dopamine after an orgasm...symptoms says.
I developed anxiety problems when about 19 whilst suffering terrible insomnia. This just made me feel so ill. Any stimulants - coffee, alcohol, cigarettes all had an amplified effect on me. I was ok before my sleeping troubles. Then my trouble started and BAM - all over the place.
I'm convinced that POIS is one of many manifestations of mercury poisoning.