0 Members and 1 Guest are viewing this topic.
I don't think that thoughts can trigger an allergy.
1899-1900 Sperm recognized as immunogenic (will cause an autoimmune reaction if transplanted from the testis into a different area of the body) by Lansteiner (1899) and Metchinikoff, (1900) Immune privilege in the testis Sperm are immunogenic - that is they will cause an autoimmune reaction if transplanted from the testis into a different part of the body. This has been demonstrated in experiments using rats by Lansteiner (1899) and Metchinikoff (1900) , mice and guinea pigs . The likely reason for this is that sperm first mature at puberty, after immune tolerance is established, therefore the body recognizes them as foreign and mounts an immune reaction against them. Since sperm do not die in the testis, mechanisms for their protection must exist in this organ. The blood-testis barrier is likely to contribute to the survival of sperm. However, it is believed in the field of testicular immunology that the blood-testis barrier cannot account for all immune suppression in the testis, due to (1) its incompleteness at a region called the rete testis and (2) the presence of immunogenic molecules outside the blood-testis barrier, on the surface of spermatogonia . Another mechanism which is likely to protect sperm is the suppression of immune responses in the testis . Both the suppression of immune responses and the increased survival of grafts in the testis have led to its recognition as an immunologically privileged site. Other immunologically privileged sites include the eye, brain and uterus. http://www.reference.com/browse/testicular+immunology
Quote from: Quasar on 02/09/2011 00:14:42So, today i tried again 100mg Niacin and i had an O. 1 hour later. I was afraid to try 200mg because first i want to be comfortable with 100mg. I noticed a flush in my ears. Niacin seemed to help with my scalp tenderness and headache after the O. This time my worst symptom was my stomach area. It's in the left abdomen, and immediately after having an O. it gets bloated and hurts. It's like having an stomach migraine or "abdominal migraine". I hate it []Can anyone confirm this abdominal pain and bloating? Specially in the left area? Quasar, is this pain in the stomach new, just with the Niacin?I often get pains in the abdomen, I have the feeling they originate in the lower abdomen area (above and to the side of the prostate) with reflections that appear higher up. In my case they're mostly on the right.
So, today i tried again 100mg Niacin and i had an O. 1 hour later. I was afraid to try 200mg because first i want to be comfortable with 100mg. I noticed a flush in my ears. Niacin seemed to help with my scalp tenderness and headache after the O. This time my worst symptom was my stomach area. It's in the left abdomen, and immediately after having an O. it gets bloated and hurts. It's like having an stomach migraine or "abdominal migraine". I hate it []Can anyone confirm this abdominal pain and bloating? Specially in the left area?
Even here in Chile believe it or not CCconfucious there is a doctor doing desensitization. For any Chileans, send me a PM and I can get you the information.Looking for Niacin is a nother situation. I found a 300mg gel cap with Vitamin C. They say that this is ALL there is made here in Chile. Sounds like a rare bird. Didn't buy it yet, it cost 20 bucks for 60 capsules. 300 mg is a lot and being a gel cap, it might be hard to divide. If it where dividable, it would be 180 doses. Still kind of expensive.And I don't know what effect Vit C would have. Probably none negative.I'm going to see if there is some other make.
Quote from: Zoop on 03/09/2011 12:59:33I don't think that thoughts can trigger an allergy.Yes and that's the whole point. Even if the thought itself activated some physiological processes resulting in an autoimmune response, it is clear, that this would happened during masturbation without ejaculating as well. But Dr. Waldinger claims, that masturbation without ejaculating does not bring POIS.
Quote from: JRD on 03/09/2011 11:27:28Quote from: Zoop on 03/09/2011 09:23:09I get POIS from excitement all alone.Different hypothesis :- i'm allergic to my pre seminal fluid (that doesn't exclude the possibility of being allergic to my sperm)- excitement trigger sperm mixing, that could be eliminated later in urine- this is not an allergyWell, take a look at this quote: “They didn’t feel ill when they masturbated without ejaculating…, but as soon as the semen came from the testes …they became ill, sometimes within a few minutes.”, which is exactly, what Dr. Waldinger said and what was paraphrased in various articles.It is counterintuitive for me to think, that an isolated sexual fantasy or getting an arousal would cause allergic reaction rather than physical masturbation (which is induced by sexual desire) without ejaculation itself.I don't think that thoughts can trigger an allergy.
Quote from: Zoop on 03/09/2011 09:23:09I get POIS from excitement all alone.Different hypothesis :- i'm allergic to my pre seminal fluid (that doesn't exclude the possibility of being allergic to my sperm)- excitement trigger sperm mixing, that could be eliminated later in urine- this is not an allergyWell, take a look at this quote: “They didn’t feel ill when they masturbated without ejaculating…, but as soon as the semen came from the testes …they became ill, sometimes within a few minutes.”, which is exactly, what Dr. Waldinger said and what was paraphrased in various articles.It is counterintuitive for me to think, that an isolated sexual fantasy or getting an arousal would cause allergic reaction rather than physical masturbation (which is induced by sexual desire) without ejaculation itself.
I get POIS from excitement all alone.Different hypothesis :- i'm allergic to my pre seminal fluid (that doesn't exclude the possibility of being allergic to my sperm)- excitement trigger sperm mixing, that could be eliminated later in urine- this is not an allergy
Quote from: Zoop on 03/09/2011 12:59:33I don't think that thoughts can trigger an allergy.It has been found that in people with multi-personality disorder, they will test positive allergic to a substance in one personality, and negative to the same substance when in their other personality.Many doctors/medicine in general are now moving away from the old Newtonian physics that drugs are the answer to chronic problems, and more towards the quantum physics way of thinking that, the mind and energy fields are the key to chronic illness, if watch you the whole of the living matrix you'll get the idea, which is why NLP & reiki etc are good for chronic illhealth.The Living Matrix //www.youtube.com/watch?v=Bl2DiT6jg88 Anyways, it has been known since 1899 that everybody are probably allergic to their semen.Quote from: horizon on 06/05/2011 22:29:211899-1900 Sperm recognized as immunogenic (will cause an autoimmune reaction if transplanted from the testis into a different area of the body) by Lansteiner (1899) and Metchinikoff, (1900) Immune privilege in the testis Sperm are immunogenic - that is they will cause an autoimmune reaction if transplanted from the testis into a different part of the body. This has been demonstrated in experiments using rats by Lansteiner (1899) and Metchinikoff (1900) , mice and guinea pigs . The likely reason for this is that sperm first mature at puberty, after immune tolerance is established, therefore the body recognizes them as foreign and mounts an immune reaction against them. Since sperm do not die in the testis, mechanisms for their protection must exist in this organ. The blood-testis barrier is likely to contribute to the survival of sperm. However, it is believed in the field of testicular immunology that the blood-testis barrier cannot account for all immune suppression in the testis, due to (1) its incompleteness at a region called the rete testis and (2) the presence of immunogenic molecules outside the blood-testis barrier, on the surface of spermatogonia . Another mechanism which is likely to protect sperm is the suppression of immune responses in the testis . Both the suppression of immune responses and the increased survival of grafts in the testis have led to its recognition as an immunologically privileged site. Other immunologically privileged sites include the eye, brain and uterus. http://www.reference.com/browse/testicular+immunology
But it may be a big step in moving towards confirmation of potential autoimmune causes for severe cognitive symptoms. For those who do not believe that an "allergy" can make you feel "out of it", "depressed", even "suicidal", the effects that niacin has over the reduction of symptoms may point to the mechanism which maybe cause those symptoms.
Hi everyone. I've posted on here briefly some time ago but not much since. I kind of avoided thinking much about POIS as I have other issues going on in my life. My POIS was triggered by starting on an SSRI medication. I don't know how or why, but I never noticed having this problem prior to taking it. I take Escitalopram. I also know of someone who took Citalopram who suffered brainfog after orgasm. My symptoms are mainly attention difficulties, difficulty focusing, aswell as motivation problems. It is very hard to be around people when in this state. I get minor body aches too. I think in my case it may be connected to the SSRI depleting my dopamine levels, which get further depleted after orgasm. Just my guess. So, from what I can see reading the last few pages, niacin seems popular? Can this be taken after an orgasm?
Quote from: daveman on 04/09/2011 15:35:30But it may be a big step in moving towards confirmation of potential autoimmune causes for severe cognitive symptoms. For those who do not believe that an "allergy" can make you feel "out of it", "depressed", even "suicidal", the effects that niacin has over the reduction of symptoms may point to the mechanism which maybe cause those symptoms.Just a little correction.
Niacin seems to be working for me. I started taking 100 mg in the morning yesterday. Made me agressive and sexually aroused. Had an O, then took 200 mg. Had another O. Not 100% by any means, but definitely feeling better than I would under the circumstances. We'll see what tomorrow brings. A few questions:1. Many of us were normal at one point, and then experienced POIS. Sometimes the development was gradual. Some have identified specific substances that maybe the trigger, e.g. Animus's herbal male enhancement and baboo's Escitalopram. So, the question is, how did they become allergic to their own semen? I suppose I have trouble with idea that one can suddenly become allergic to their own semen. If it was a birth disorder, then it would be more acceptable. But, the idea that SSRI's or other neurochemical altering substances can "trigger" POIS leads me to believe there is more to it than a very intense allergic reaction.2. The quote Horizon provided from reference.com is fascinating. It basically states that all people can be allergic to their own semen: "Sperm are immunogenic - that is they will cause an autoimmune reaction if transplanted from the testis into a different part of the body." This raises the question of whether intradermal tests actually tell us anything. Furthermore, as many have pointed out, and as one allergy dr. my endocrinologist phoned during my appointment immediately identified, there is no control group in Waldinger's work. According to the research cited, the photos Habibou shared do not show anything unexpected. 3. The symptoms of sexual exhaustion seem to be very similar, if not identical, to those of POIS. This may also explain why multiple O's will lead to more severe POIS symptoms. Simply because many people can have multiple O's in one day without any consequences does not rule out that some can become extremely fatigued after one. But, I do believe there is more to POIS than just exhaustion. I would like more investigation into the condition of the blood-testis barrier and the rete testis in POIS sufferers. Could it be that we have damaged this mechanism? This may explain why some people develop POIS after years of normality. But, why would SSRI's or herbal male enhancements lead to this? Maybe they are red herrings. Or, they effected the mechanism in a way that made it more vulnerable to damage. My endocrinologist can not make sense of why anti-histamines have no effect whatsoever. He's gone so far as to recommend I make the trip to Holland. He also recommended I see Dr. Arthur Burnett. He's a big shot urologist at John's Hopkins. Let's see what he thinks. Looking forward to your thoughts.
"Saw palmetto is used by natural health practitioners to treat a variety of ailments in men and women, such as testicular inflammation, urinary tract inflammation, coughs, and respiratory congestion. It is also used to strengthen the thyroid gland, balance the metabolism, stimulate appetite, and aid digestion."http://medical-dictionary.thefreedictionary.com/saw+palmettoSince saw palmetto makes my testicles much less tender and takes away the burning feeling that usually accompanies urination, these facts provide evidence of actual inflammation in my body resulting from orgasm. Saw palmetto also reduces the bloating I have during POIS and makes bowel movements less painful which is evidence that POIS causes my intestines to become inflamed or my digestion to become hindered in some way.