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New Theories / Re: Insulin myths and the science that broke through
« on: 27/06/2022 10:41:54 »If insulin was not needed for glucose transport and only functioned to to aid adipose deposition the illness of diabetes mellitus with all it's ravages would not exist.
Thank you very much for your reply Paul!
See that is exactly why I want to revisit this. That is exactly why I collected the medical literature and attempted to make this narrative. Too bad I seem to have failed to communicate the findings. I seem to have failed to help you understand the last 40 years of scientific study:
- Hyperglycemia in diabetes is caused by hepatic glucose production. Sonksen 2000, BJA, Sheehan 2004
- Hepatic glucose production is caused by glucagon, as result of absence of insulin.(quote from Sonksen 2000)
- Basal glucose transport happens without insulin. Waller 2013
- Glucose transport into cell does not require insulin activation.
- Insulin activation of glucose transporters seems to happen under exercise.
- Obesity is a hormonal phenomena, caused by hormones, not energy equations.
It simple to write that off. But thats not what the research says.
In other words, there is a whole other "layer" of events to this glucose metabolism, just as there is to energy storage and hormonal signaling. Sorry I failed to convince you. Have a great summer!