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New Theories / Re: Controversial ideas on DNA... any thoughts?
« on: 27/08/2020 11:47:29 »
Back in the 1950's an controversial observation was made in biology. It was discovered that proteins fold with exact folds. This was controversial then and even now because this observation was not anticipated by the statistical modeling of cells that had grown popular. The statistical models, then and now, assumed proteins should fold with average folds due to thermal vibrations and other randomization affects. It is almost 70 years later and there is still no good statistical explanation for this, even though it is a well established experimental fact. Something is still missing from the status quo explanations of life, which often raises questions in the minds of young scientists.
The explanation, which is still not mainstream, as evident by the DNA never shown with water in textbooks, is connected to water. The cellular water, in an attempt to lower its potential, is forcing the protein to assume minimal energy states, which make them ideal surface for the dynamics of catalysis; CPU. The CPU of the cell, is not into dice, but has a logical plan based on free energy, with evolution part of this plan.
Below is what is referred to as free energy landscape diagrams. This diagram show two states of a protein in water.
Image b represents a protein hot off the press, that has been synthesized. It is random in many sense. Image A shows the same protein after water packs it to minimize the free energy of the protein-water cooperative.
The hills and peaks in image b represent the various organic rich side groups that create the most potential in water; surface tension. These are packed first; core of the protein and thereby shielded from the water, since the packing of these highest energy will minimize free energy the fastest.
Image A reflects the perfectly packed protein with a surface that is favorable to water; CPU. Water tries to do this everywhere with each type of protein and material having a different optimized potential. This sets priority and helps to establish the protein grid of the cell. The DNA is at lowest potential with the water. As the cell interacts with the environment and reduced materials enter; food, the global water potential increases, which increases the potential at the water and DNA hard drive. This gets the DNA into the game with its response tailored to the global and local CPU.
The explanation, which is still not mainstream, as evident by the DNA never shown with water in textbooks, is connected to water. The cellular water, in an attempt to lower its potential, is forcing the protein to assume minimal energy states, which make them ideal surface for the dynamics of catalysis; CPU. The CPU of the cell, is not into dice, but has a logical plan based on free energy, with evolution part of this plan.
Below is what is referred to as free energy landscape diagrams. This diagram show two states of a protein in water.
Image b represents a protein hot off the press, that has been synthesized. It is random in many sense. Image A shows the same protein after water packs it to minimize the free energy of the protein-water cooperative.
The hills and peaks in image b represent the various organic rich side groups that create the most potential in water; surface tension. These are packed first; core of the protein and thereby shielded from the water, since the packing of these highest energy will minimize free energy the fastest.
Image A reflects the perfectly packed protein with a surface that is favorable to water; CPU. Water tries to do this everywhere with each type of protein and material having a different optimized potential. This sets priority and helps to establish the protein grid of the cell. The DNA is at lowest potential with the water. As the cell interacts with the environment and reduced materials enter; food, the global water potential increases, which increases the potential at the water and DNA hard drive. This gets the DNA into the game with its response tailored to the global and local CPU.
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