[tintinxx (OP)]

Could anyone explain the center surround receptive system in relation to ON/OFF bipolar cell and lateral inhibition by horizontal cells, please?  []

Thank you!!  [:I] 

[Andrew K Fletcher]

This might be a good starting point to understanding a few problems that change sight by affecting the cones in the eye.

http://www.brps.org.uk/Graphics/G_Guide.html