[Bored chemist]

It is almost 70 years later and there is still no good statistical explanation for this, even though it is a well established experimental fact. Something is still missing from the status quo explanations of life, which often raises questions in the minds of young scientists.

No.
It is not missing from science.
It's just that you persist in ignoring things like this
https://en.wikipedia.org/wiki/Chaperone_(protein)
because they don't fit with your pipedreams.

I think I get the gist but it's perhaps a bit beyond my understanding!

It's beyond Puppypower's understanding too.
But he keeps banging on about it.