[cpu68 (OP)]

Logistic theory clearly illustrates and can explain so called "Cambrian explosion" (590-545 millions of years).

[cpu68 (OP)]

- Type I, planetary, is connected with transition inside simple backward culture, about 10000 BC
- Type II, civilization which is entering in interplanetary space, is connected with transition from simple backward culture to complex scientific culture, present and future time
- Type III, which is entering in interstellar space, far future, this phase will also be a phase of biological transition from a relatively small braincase to a much larger one, which will be controlled by genetic engineering.

[cpu68 (OP)]

Of course, such an enlarged braincase will not have huge dimensions.

[Wellwisher]

One of the practical problems, with the genetic centric theory of evolution is, although the the DNA is useful to explain the changes in protein, the DNA has little impact, on critical stages, such as the folding and packing protein, and positioning these, so they can be useful and evolutionary.

The mRNA, hot of the DNA press, all by itself is very limited. This does not define life. It still needs to process further to make protein. While as these protein comes off the ribosomes, they are not already folded or able to do anything, nor does the DNA direct them where to go. There are still many things to be don, beyond the DNA, yet DNA gets all the credit. This model glosses over these shaping and placement steps, needed to become alive and useful.

Conceptually, the graph steps, shown in the first post, appears to show these organization steps. To bump up to a new level. there is a lot of sorting to do and placement of new protein, and the rejection of useless or obsolete protein from the DNA, since the theory assumes random. The DNA is not perfect and needs help. The cell or animal needs to sort that out, to evolve. This takes time.

The DNA appears to have and also needs a partner. The DNA brings home the bacon, but something else cooks it and place on plates as tasty meals; DNA's partner. If we knew more about  this partner, what the DNA does, may not seem so random. The partner may wish to make a cake and asks the bacon provider, it also needs eggs and milk.

The most logical co-partner is water. Water was there even before replicators or DNA. It was there even during abiogenesis. That would make DNA, water's partner, since DNA  will only work in water; it is monogamous to water. It will not work in any other solvent.

Enzymes for example, have their hydrophobic moieties packed into the core of the enzyme. These cause the most surface tension with water, and are buried by the water to lower surface tension.  Most other solvents, proposed for life, are good degreasers and would pack the protein inside out. Even ammonia is a good degreaser and would not allow the DNA double helix to form but would keep it dissolved as separate helixes. Water tries to bury the hydrophobia aspect of the DNA, as a double helix, to lower its own surface tension. RNA is more like a single helix since its sugars and one of its bases is less hydrophobic compared to DNA. Water packs; dresses, her partner.

When you think of it DNA, RNA and all Protein evolved in water. They were naturally selected by water, at the nano-scale, which is why they only work in water. It is like the Arctic selected the polar bear, due to his dense thermal coat. This will not work well in another (chemical/solvent) environment like the tropics.

The water selected DNA to be its partner and DNA only has eyes for water; does not work with other solvents. It stays monogamous to water.

Interestingly, water has not changed since before even abiogenesis began; steam. Water is the same today and even the foreseeable future. It is like an eternal bookend partner. It has seen it all; evolution. This adds a steady anchor and the vector for evolution. The DNA on the other hand, is fickle and is always changing with time. The unchangeable and the changeable became partners.

Water chemical properties are based on hydrogen bonding. In a sense, water also taught the DNA hydrogen bonding. Or that it was natural selected since thy had this in common. DNA also has a double helix of water within major and minor groves of the DNA. Water keeps an eye on DNA, since DNA is fickle and needs to tow the line.

[img]https://water.lsbu.ac.uk/water/images/nuclei.gif/img]

[cpu68 (OP)]

One of the practical problems, with the genetic centric theory of evolution is, although the the DNA is useful to explain the changes in protein, the DNA has little impact, on critical stages, such as the folding and packing protein, and positioning these, so they can be useful and evolutionary.
...
Water chemical properties are based on hydrogen bonding. In a sense, water also taught the DNA hydrogen bonding. Or that it was natural selected since thy had this in common. DNA also has a double helix of water within major and minor groves of the DNA. Water keeps an eye on DNA, since DNA is fickle and needs to tow the line.

Very interesting arguments Wellwisher.

[Wellwisher]

One of the practical problems, with the genetic centric theory of evolution is, although the the DNA is useful to explain the changes in protein, the DNA has little impact, on critical stages, such as the folding and packing protein, and positioning these, so they can be useful and evolutionary.
...
Water chemical properties are based on hydrogen bonding. In a sense, water also taught the DNA hydrogen bonding. Or that it was natural selected since thy had this in common. DNA also has a double helix of water within major and minor groves of the DNA. Water keeps an eye on DNA, since DNA is fickle and needs to tow the line.

Very interesting arguments Wellwisher.

Water is the shape maker of life. For example, the bi-layered lipid membranes of all cells do not randomly form. This specific bi-layer shape, is the shape that minimizes surface tension in water. The organic moieties get buried inside the sandwich, and polar moieties face the water.


This shaping of life materials, by water, can be understood as being similar, to the water and oil effect. If we mix water and oil; add energy, we can form an emulsion, which appears all random like a solution. But this is not stable. If we wait and let it settle, the water and oil will separate, driven by the lowering of surface tension. This shape shifting lowers the system energy, that we added via agitation. In abiogenesis, the high tide might mix random organics to form an emulsion with water.  As the tide goes out, pools of this emulsion settle, and will lower surface tension; water and organic phase separation. A sorting process begins to occur.

In this model, the organics of life; DNA,RNA, Protein, fats, etc., are analogous to "oil" and when they appear in water, a variation of the water and oil effect form; some degree of surface tension. The water helps to pack the same shapes, each time, since these specific shapes create minimal surface energy potential.

When enzymes are packed, the most hydrophobic moieties, create the most surface tension in water; most oily. These groups always pack first, thereby lowering the surface tension, fastest. The water, in essence, sets packing energy priority, to get to the sweet spots, as efficiently as possible. This results in repeatable bio-material shapes

Even the organic DNA is treated like "oil" in water. The lowering of the surface tension in water encourages the double helix to help bury the organic bases and sugars, as well as adding pressure to the double helix; squeeze, thereby making the DNA even more precise, since it now takes deliberate enzymatic work to expose base pairs; need to fight the water, deliberately.

The rational for why water is the universal shape maker of life, is the fluid and reversible nature of life's molecules, is based on secondary bonding. The primary or covalent bonds of DNA keep the extremely large/long DNA molecules whole. It is the secondary bonding; hydrogen bonds, between base pairs, that is the essence of life. These weaker secondary bonds, can form and break, without harming the main bonds. These secondary bonds can be used again and again for the same genetic expression, with no harm to the DNA backbone. This duality is critical to fluid genetic reliability; secondary bonds, and long term stability; primary bonds.

Water is the king of secondary bonds, when it comes to life. Water also has primary bonds between oxygen and hydrogen; O-H. Water also forms strong secondary bonds with other water molecules, via hydrogen bonds. The organics of life; oil, is more often Van der Waals types secondary bonds, which are weaker than hydrogen bonds. While each little water molecule, by comparison, can form up to four stronger hydrogen bonds. This collectively adds up to water having the dominant secondary bonding power. Water wants to self bond; optimized, and this will put the squeeze on the oil; shapes them.

The accumulative effect of the water's secondary bonding, with water the main component of life, is that the liquid water matrix is the "big dog" of secondary bonding within life. All the; "oil", is modified, by water, to allow water to optimize; lowest surface tension. This is why enzymes are packed with their worse surface tension in water groups buried. This optimizes water; the big dog. There are 100 times as many water molecules in the cell, as all the rest "oil" combined. Multiple this by four hydrogen bonds each water molecule. This matrix has a very powerful self goal. Water is like a large army of ants that keep the cellular house organized, in a way to optimize the colony; lowers the global surface tension to create a favorable water energy balance.

Evolution, started with replicators. As a visual, as the replicators made new RNA materials, water immediately began house keeping, to maximize itself; secondary bonding big dog. Even if the replicators, were not very useful or precise, yet, their output is still got organized. The goal of the water was and still is, optimize itself.

Flash forward in time; Say water packs all the intermediate stage replicator created protein, into minimal energy shapes. The "best" enzymes become more stand-alone, with a surface that is very agreeable to water. The less than perfect, still have residual surface tension. These will get combined and balled up with other junk protein. Now we have also at some "good enzymes"; solo enzymes, to do additional work. Water takes away the random, since the water has sweet spots, that are energetically favorable; reproducible.

If we go back to abiogenesis, before the replicators, and we have a bunch of random proteins made by other non life process; clay. The water and oil effect, is already in effect, The water will pack these. Since it is so early in the story of life, most of these protein may have residual surface tension with water. Water will combine them, to hide these residual energized areas. This is why we have organelles, these organelles, as a team, minimize the surface tension in water.

One older, but advanced example, that is still in effect, is the packing of the DNA with packing protein to form chromosomes. These packing protein are compose of histone protein, with long carbon chains. These are very "oily". Water will combine these protein, into groups, to lower surface tension, but that does not totally lower surface tension. Water looked for another way to combine, which becomes the DNA.

The combined DNA and packing protein minimize the water's surface tension. The DNA covers the packing protein, to help shield the water. This is very stable. It needs unpacking enzymes to reverse this packing, making genetic expression even more directed, since these will not self unpack, due to the water resisting.

But even the unpacking enzymes are directed by water, since when they attach to the packed DNA, this composite helps water. However, the enzymatic potential water added earlier; original enzyme shaping, sets the enzyme up, for success later; catalytic reversal. However, this exposes the packaging protein and adds surface tension. Water might send now send it to recycle; new equilibrium to lower global surface tension.

The key points to remember is the fluid nature of life is based on reversible secondary bonds. Water is the king of secondary bonds, with four hydrogen bonds per tiny water molecule, and there 100 times as many water molecules as all the "oil" molecules combined.

Through the water and oil effect, water, as the big dog of secondary bonding, shapes the organics; oil, to optimize both the local and global water colony. This action, over time, caused water to naturally select  RNA and then DNA, since they were optimizes to the aqueous  environment; optimize the water. This is why DNA will not work in any other solvent. Both water and oil (DNA and his offspring) need each other, with the team more than the sum of its parts.

[cpu68 (OP)]

Wellwisher, you rightly emphasize the importance of water for life processes, water is the basis of life.

[cpu68 (OP)]

I use the same logistic concept in sociological theory.

[cpu68 (OP)]

It is not known how long we will have to wait for this third phase.

[cpu68 (OP)]

But after thousands of years this phase will come.

[cpu68 (OP)]

Logistic model is an interesting model for model of evolution.