How are genetically modified (transgenic) animals made?

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Ian Baxter

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Ian Baxter  asked the Naked Scientists:

Chris

Love your show, I listen to it while driving, and I always phone my  
kids to tell them to do the Kitchen Science experiments, then when I  
get home I ask them to tell me what happened and I explain the science behind it to them.  Great fun!

I want to ask about how genes are modified in lab rats - Is just one  
cell modified and it replicates, thereby having the effect of changing  
genes in lots of cells?  Once scientists find out a gene does a  
certain thing and they want to change it, how do they effect the same  
gene modification in the all the cells?  I hope I am asking the  
question clearly?

Thanks for a great show.

Ian Baxter
Atlanta GA

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Offline biolight

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How are genetically modified (transgenic) animals made?
« Reply #1 on: 22/10/2008 19:52:40 »
I want to ask about how genes are modified in lab rats - Is just one 
cell modified and it replicates, thereby having the effect of changing 
genes in lots of cells?  Once scientists find out a gene does a 
certain thing and they want to change it, how do they effect the same 
gene modification in the all the cells?  I hope I am asking the 
question clearly?
We are created by two cells. The rats is not exclusion. Even if  we do not disturb the ovum in the female`s  organism, the male`s genetic material , which brings with spermatozoids, we can change in test tube, and deliver it by the instrumentality of syringe.
Later, fertilized ovum will be divide. And we will have a cells (so and organism)  with changed genome.