Post Orgasmic Illness Syndrome (POIS)

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Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17700 on: 28/01/2013 12:00:24 »
can taking anti histamine tablet  after or before O effects POIS

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Offline Joe Burger

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Post Orgasmic Illness Syndrome - antihistamine treatment
« Reply #17701 on: 28/01/2013 12:02:25 »
Back story:  I'm a "textbook" sufferer - Wikipedia's POIS entry could have been written for me. 

Last April I saw Dr. Goldmeier in London, who prescribed an antihistamine called Xyzal (levocetirizine dihydrochloride).  This belongs to a group that is less likely to cause drowsiness than older antihistamines.  A single 5mg. tablet taken an hour or two before sex relieved my symptoms, but left me fairly drowsy the following day - nothing that a few stiff coffees and a siesta couldn't sort out - but it affected my sleep cycle.  Whilst it was a big improvement, it wasn't an ideal remedy.

Recently I saw my GP and asked to try a different non-drowsy antihistamine.  He prescribed desloratadine ratiopharm 5mg.  A single tab, again taken an hour beforehand, relieved my symptoms 100%, and did not leave me at all drowsy - in fact I ran around the next day as if my tail was on fire.  The second time was similar.  Needless to say I am completely delighted!  I didn't feel a single side-effect. 

As a word of caution I would point out that I have only tried this twice, but anticipate that it will continue to work as well in the future.

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Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17702 on: 28/01/2013 13:58:26 »
High daily doses of Zinc and Vitamin B6 completely solved the problem for me. Please look up "Pyroluria" on Google. There's plenty of writing on the matter.

POIS was a symptom of Pyroluria for me (there are other symptoms, and POIS isn't traditionally one of them). It is very straightforward to try the supplements and see if it works.

I take 150mg Zn and about 200mg Vitamin B6 (Pyridoxine) every single day. If I "O", I take 50mg Zn and 80mg B6 an hour two after (on top of my daily regular does).

My POIS symptoms were:
1. Sore throat and pain in tonsils (usually right one)
2. Blood shot eyes
3. Brain fog
4. Irritability
5. Fatigue and weakness

Every one of these symptoms is gone now. I do still get bloodshot eyes if I don't take the extra Zinc and B6 about 1 to 2 hours after I "O". Once I take them (say 4 hours after), the bloodshot eyes go away. No other symptoms show up even if I skip this extra dose as long as I'm taking my daily dose (150mg Zn and 200mg B6).

To repeat, look up "Pyroluria" on Google and just try the higher doses of Zn and B6 supplements. If you don't see improvements quickly (a day or two), then this may not be the solution for you. For those that it does work for, I think it will work very quickly and will be obvious that it is a solution for you.

Good luck.

I had a look on Pyroluria...its interesting ; I definitly fit the B6 deficiency symtoms, not that much for the zinc ones.The thing is ; can Pyroluria be sporadic ? Pois is definitly sporadic

Just a few more questions : How long have you been testing this regimen ? Did you have cognitive symptoms that made difficult any profesional or social relations(especialy comparated to situation you are POIS free)? Did orgasm or even sexual activities triggered symtoms ?

thanks

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Offline Gbolduev

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17703 on: 28/01/2013 16:29:57 »
 Pyroluria is  copper / zinc imbalance 

So is POIS. 

This is also imbalance between adrenal and thyroid/    Low histamine levels   high copper,    high histamine low copper.
High ferritin  relatively   low copper,,  low ferritin high copper.   

Lacosse,  it is better to try high  zinc dosage.  most people are high in copper.

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Offline Gbolduev

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17704 on: 28/01/2013 16:35:12 »
LAPOISSE

if you are copper toxic,  and you take zinc  you will  feel like   so shitty it is not even funny.   That is why  most people  dont go thru it/     If they  go by how they feel.   Copper will be dumped in the blood and  it will make  your mind race . and anxiety will go up big time /   That is why   for first week, it will feel bad and  then boom and your energy  skyrockets.
More complicated when you are copper deficient...Since   adrenal place  a part in it  big time, that is why you ahve to  take stress off adrenal, let it make more  ceruplasmin  and take on the copper. or   take   bound  copper if you  kind find that.

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17705 on: 28/01/2013 16:55:09 »
Nightingale, the hygiene hypothesis and helminthic therapy are very interesting. I wish doctors would be more open minded about it.
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17706 on: 28/01/2013 17:56:22 »
Gbolduev, I've read that zinc can decrease copper absorption and utilization, but the way I see it that would increase bio-unavailable copper and make a copper toxicity problem worse. Does zinc also somehow neutralize free unavailable copper in the body or help rid the system of it somehow?
« Last Edit: 28/01/2013 17:58:00 by Vincent M »
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline Gbolduev

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17707 on: 28/01/2013 18:15:38 »
Vincent  M

Zinc and copper and iron compete in the gut /  Also they are direct antogonists in  the tissues/

Zinc /copper ratio is very important,     zinc  is more associated with progesterone and copper with estrogen...Also  Zinc and copper  is  thyroid  ratio. zinc increases pottasium in the cell  making   thyroid hormones more sensitive to the cell  and   copper lowers it.    Cortisol  is connected with progesterone .  And  depletes zinc  by which  increases copper levels for the immune response

I hope this helps

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17708 on: 28/01/2013 18:16:16 »
I found an old study from 1989 that seems to show how glutathione(GSH) might be helpful for copper toxicity:

"Cellular copper metabolism and the mechanism of resistance to copper toxicity were investigated using a wild type hepatoma cell line (HAC) and a copper-resistant cell line (HAC600) that accumulates copper and has a highly elevated level of metallothionein (MT). Of the enzymes involved in reactive oxygen metabolism, only glutathionine peroxidase was elevated (3-4-fold) in resistant cells, suggestive of an increase in the cellular flux of hydrogen peroxide. A majority of the cytoplasmic copper (greater than 60%) was isolated from both cell lines as a GSH complex. Kinetic studies of 67Cu uptake showed that GSH bound 67Cu before the metal was complexed by MT. Depletion of cellular GSH with buthionine sulfoximine inhibited the incorporation of 67Cu into MT by greater than 50%. These results support a model of copper metabolism in which the metal is complexed by GSH soon after entering the cell. The complexed metal is then transferred to MT where it is stored. This study also indicates that resistance to metal toxicity in copper-resistant hepatoma cells is due to increases in both cellular GSH and MT. Furthermore, it is suggested that elevated levels of GSH peroxidase allows cells to more efficiently accommodate an increased cellular hydrogen peroxide flux that may occur as a consequence of elevated levels of cytoplasmic copper."
http://www.ncbi.nlm.nih.gov/pubmed/2564391

I think the best way to raise glutathione levels is to take N-acetylcysteine. What do you think of this, Herman?
« Last Edit: 28/01/2013 18:21:55 by Vincent M »
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline Gbolduev

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17709 on: 28/01/2013 19:14:50 »
N-Acetyl Cysteine (NAC) is a synthetic version of Cysteine that is rapidly converted to the amino acid Cysteine. NAC supplements are moderately effective, but dosing is limited due to the toxic side effects (such as headaches, dizziness, blurred vision) associated with Cysteine Supplementation. NAC decreases Zinc, so supplementing with additional zinc and copper is recommended along with Vitamin C to prevent the Cysteine from converting to Cysteine, which can form kidney and bladder stones.

Recent Study on NAC:
According to recent research at The University of Virginia, N-Acetyl-Cysteine forms a red blood cell derived molecule that makes blood vessels think they are not getting enough oxygen. This leads to pulmonary arterial hypertension (PAH), a serious condition characterized by high blood pressure in the arteries that carry blood to the lungs. The results appeared in the September 2009 issue of the Journal of Clinical Investigation.



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Offline Gbolduev

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17710 on: 28/01/2013 19:48:23 »
Copper-treatment increases the cellular GSH content and accelerates GSH export from cultured rat astrocytes.
Ivo F Scheiber, Ralf Dringen
Center for Biomolecular Interactions Bremen, University of Bremen, D-28334 Bremen, Germany.
To test whether copper exposure affects astroglial glutathione (GSH) metabolism, we have exposed astrocyte-rich primary cultures with copper chloride in concentrations of up to 30 μM and investigated cellular and extracellular GSH contents. Cultured astrocytes accumulated copper in a concentration-dependent manner thereby increasing the specific cellular copper content within 24h up to sevenfold. The increase in the cellular copper content was accompanied by a proportional increase in the specific cellular GSH content that reached up to 165% of the values of cells that had been incubated without copper, while the low cellular content of GSH disulfide (GSSG) remained unaltered in copper-treated cells. Also the rate of GSH export was significantly increased after copper exposure reaching up to 177% of control values. The export of GSH from control and copper-treated astrocytes was lowered by more than 70%, if cells were incubated in presence of the multidrug-resistance protein (Mrp) 1 inhibitor MK571 or at a low incubation temperature of 4C. These data demonstrate that copper accumulation stimulates GSH synthesis and accelerates Mrp1-mediated GSH export from cultured astrocytes. These processes are likely to contribute to the resistance of astrocytes against copper toxicity and could improve the supply of GSH precursors from astrocytes to neurons.


also interesting   done in 2011

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Offline Prancer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17711 on: 28/01/2013 23:26:41 »
Hi Herman, are you able to have as many orgasms as you want (without any pois symptoms) now that you're cured? Thanks! It's very interesting & I enjoy reading your posts.

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17712 on: 29/01/2013 00:34:08 »
I can't find a reliable source that says N-acetylcysteine decreases zinc. I looked at the website you got that info from and they do list some of their sources, but not the source for that fact.

I found a source that seems to say that isn't true(at least not at normal supplemental doses):

"N-Acetylcysteine (NAC) is known to decrease the exacerbation rate in patients with chronic bronchitis. It has also been shown that NAC has both an oxygen-radical scavenger and a heavy-metal chelating effect in high intravenous doses. In a study lasting 5 weeks, 10 healthy volunteers were treated with NAC 200 mg t. d. s. for two weeks. The concentrations of trace metals (Ca, Mg, Fe, Zn & Cu) in plasma were measured weekly and daily in a morning spot urine during the investigation.
No significant change in plasma concentration or excretion was found during the two weeks of treatment, implying that additional administration of trace metals is unnecessary for patients treated perorally with a therapeutic dose of NAC."
http://link.springer.com/article/10.1007%2FBF02657052?LI=true
« Last Edit: 29/01/2013 03:42:46 by Vincent M »
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline Prancer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17713 on: 29/01/2013 05:11:07 »
Hi,

I found a few sources that say NAC decreases zinc. They are: http://www.advance-health.com/nacetylcysteine.html [nofollow] (look under N-acetylcysteine Chelates Heavy Metals), http://www.herbs2000.com/h_menu/nac.htm [nofollow] ("N-acetyl cysteine also augments emission of zinc as well as additional essential minerals when it is taken for a prolonged period of time."), and http://www.psycheducation.org/depression/meds/n-acetylcysteine.htm [nofollow] ("NAC has been studied for use as a means of treating heavy metal exposure. If it works to pull those metals out, maybe with long-term use it could pull out other body metals, like copper or zinc").

I don't know how reliable those sources are, but there are others too.

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17714 on: 29/01/2013 05:54:44 »
None those sources are reliable or cite any scientific studies. I think it only decreases zinc when it's injected in higher than normal amounts, but I guess it's not a big thing to worry about.
« Last Edit: 29/01/2013 05:56:55 by Vincent M »
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17715 on: 29/01/2013 14:56:06 »
no one wants to reply to me but i will keep asking :-'(...can taking anti histamine tablet  after or before O effects POIS

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Offline Nightingale

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17716 on: 29/01/2013 15:08:39 »
no one wants to reply to me but i will keep asking :-'(...can taking anti histamine tablet  after or before O effects POIS

I have found some benefit from taking antihistamines before O, so I take some before each time

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Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17717 on: 29/01/2013 17:35:16 »
I've tried anti histamine few times before and after ; Really difficult to say if it has any benefit ; POIS is not always the same intensity ; Anyways, nothing magik ;

I'll try the copper thing taking Zinc and B6 ; my feritin is quite low...i'll see

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17718 on: 29/01/2013 18:03:30 »
no one wants to reply to me but i will keep asking :-'(...can taking anti histamine tablet  after or before O effects POIS

Some of our members have been helped by antihistamines, myself included. Claritin (Loratadine) seems to have helped the most POIS members. If you take it you should take it about an hour before orgasm.

However I've recently read about some people getting joint pain from Claritin and other antihistamines so I have stopped taking them for now.

My treatment summary: http://poiscenter.com/forums/index.php?topic=81.msg3513#msg3513
« Last Edit: 29/01/2013 18:35:15 by Vincent M »
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17719 on: 29/01/2013 21:40:52 »
Nightingale, the hygiene hypothesis and helminthic therapy are very interesting. I wish doctors would be more open minded about it.

Here's an article in a similar vein.
http://www.huffingtonpost.com/dr-mark-hyman/how-to-stop-attacking-you_b_657395.html
One of the things he mentions is treating yeast infections. If you have obvious yeast infections (I'm thinking recurring penile thrush for example) you have to get it treated. If it keeps coming back and your partner doesn't have it then your doctor hasn't treated it successfully.
There are better drugs now for dealing with systemic fungal infections & no, I'm not saying POIS is candidiasis. 

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Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17720 on: 30/01/2013 07:57:31 »
can we ejaculate while peeing? and can we get POIS from this or can we get POIS from pre ejaulate or semen???please reply this is my big fear while peeing

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Offline B_Daniel

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17721 on: 30/01/2013 15:28:31 »
can we ejaculate at the same time as peeing?  Nope, I've never been able to do that.  I do those 2 functions separately.... Kinda like shnapping.  Shitting and Taking a nap.  You can do one and then the other, but you can't really do them both at the same time
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.

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Offline Limejuice

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17722 on: 30/01/2013 16:24:06 »
+1 for shnapping

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Offline Gbolduev

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17723 on: 30/01/2013 20:15:48 »
Daniel,

I think it happens  when there is  sperm in the urine.  May be that is what he meant.   When you pee , sperm comes out.   
If that happened to him, he needs to go to a doctor and get it treated  .. Usually this is  the result of severe overmasturbation.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17724 on: 31/01/2013 09:42:25 »
Seminal fluid in the urine can be caused by prostatitis

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Offline aks020

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17725 on: 31/01/2013 09:49:00 »
I only get allergy and it converts to cold or cough after sometime after masturbation or night fall.Also problem is sneezing continously for 20-25 times or even more , no other problem is this POIS.


i get cold that is in the form of allergy (that is running nose and sneezing) almost after masturbation or even if i get night fall.
I am 100 % sure about it , if i dont do masturbation for say 7 - 10 days then i dont get cold (allergy that is running nose and sneezing) for that period of time .
Sneezing continously for 20-25 times is too much to handle for me .
Allergy last for 2-3 days if i dont take any medicine .
so i take anti allergy drug and get relive many times. is there any cure for it that is permanent .
i do heavy weight training everyday 7 days a week and i think this way i get some relive and i am fit and i dont get tried after doing workouts .
mine age is 29 years and i never involved in sex till now .
i want to ask if i get married and do sex then also will i get same
thing, if yes that will be a problem as i cant do much in a week.
Is there name for this disease or what it is called .

Hi,
Welcome to the board.

You may have POIS or Post Orgasmic Illness Syndrome. POIS, as we understand it, is a syndrome that affects some people after they have an orgasm by making them feel ill. However, different sufferers have different symptoms. Some have mainly headaches and cognitive problems. Some have more flu-like symptoms. Some feel more fatigue than others.
It may not be a single disease and therefore there may not be a single cure.

As your symptoms are mostly allergic, have you been to your doctor to discuss allergies?
Your doctor may be able to refer you to a specific allergic or immunologist who can
1) perform tests
2) prescribe medication that may help you deal with itching, sinus problems etc.

i dont get any itching , what is sinus , i get only allergy which converts into cough or cold after some days. yes i do take allergy tablet and sometimes it works but sometimes not
thanks

What allergy tablets are you taking?
Doctors sometimes prescribe ketotifen or  leukotriene receptor antagonists for allergies when anti-histamines don't work effectively. I'd give you brand names but these are now "blacklisted terms" of the forum.
Ask your doctor about it? If they don't know then perhaps they could refer you to a specialist.

i take different types of tablets as in few weeks it dont works any more,  and that tablet is difficult to get as medical store person tells we cant give as this cause sleepiness after taking but asking him again and again they give the tablet.
thanks

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17726 on: 31/01/2013 20:30:08 »
I've taken a mast cell stabiliser that did not make me drowsy. Perhaps you could talk to your doctor about this. They're prescription only.

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Offline meteo74

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17727 on: 03/02/2013 11:04:02 »
what good news about pois??

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17728 on: 08/02/2013 20:01:05 »
I've been taking a highly bio-active B-Complex once a night for the past 24 days. 7 days into b-complex I started 500mg of acetyl-L-carnitine morning and night for 13 days. About 4 days after I started ALC I noticed an improvement in my joint pain, muscle strength, eye burning, face irritation, scalp itchiness, and perhaps cognition.

I also took 500mg methionine once a morning for 6 days starting at day 7 of B-complex/ALC, but it seemed to cause a slight worsening of symptoms.

For the past 4 days I've only been taking B-complex to determine whether it or ALC or both were improving my symptoms. I still feel improved symptoms, but it might be a residual effect of the ALC.

This is the B-complex I'm using: http://www.swansonvitamins.com/swanson-ultra-activated-b-complex-high-bioavailability-60-caps

Thiamin (vitamin B-1)                              54.4 mg   3,627%
(as benfotiamine)                                     
Riboflavin (as riboflavin 5'-phosphate)       50 mg   2,941%
Niacin (as inositol hexanicotinate)              100 mg   500%
Vitamin B-6
(as pyridoxal 5-phosphate)                       50 mg   2,500%
Folate                                                   800 mcg   200%
(as Quatrefolic? [6S]-5-Methyltetrahydrofolic acid equivalent to 1.6 mg of [6S]-5-Methyltetrahydrofolic acid, glucosamine salt)
Vitamin B-12                                           500 mcg   8,333%
(as methylcobalamin)
Biotin                                                      50 mcg   17%
Choline                                                   50 mg   *
(as choline dihydrogen citrate)
PABA (para-aminobenzoic acid)               50 mg   *
Pantethine (coenzyme A precursor)           50 mg   *
(from Pantesin? 80% pantethine)
Inositol                                                   25 mg   *
(from inositol hexanicotinate)

After analyzing my diet I noticed it looked low in b vitamins. This is the site I used to determine this: http://nutritiondata.self.com/
« Last Edit: 10/02/2013 17:47:56 by Vincent M »
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17729 on: 09/02/2013 12:04:55 »
As the body uses methylcobalamin (methylated via methyfolate) to recycle methionine from homocysteine, adding more methionine may actually reduce the body's production of its own methionine which may lead to build up of the folic acid you take. Many biological reactions are rate limited, meaning in this case that the presence of SAM-e downstream from methionine you don't make yourself could rate limit the methylation process. I suspect this is a big problem with people taking SAM-e. They feel better as their bodies aren't getting enough SAM-e but they're throwing their bodies out of whack by not giving their bodies the enzymes to make SAM-e effectively themselves.

My genetic test suggested I needed methylfolate and methylcobalamin. Perhaps some extra NADH to help recycle BH4. I gave up taking taking methionine supplements.

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17730 on: 09/02/2013 13:23:57 »
Do you still take SAM-e?
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17731 on: 09/02/2013 16:50:51 »
Vincent M: No, for the same reason. The methionine cycle is explained here.
http://en.wikipedia.org/wiki/S-Adenosyl_methionine

I think that depending on someone's genetics, they may feel better when they take methionine or SAM-e. If so I believe a better way to achieve the same improvement is to look a few steps prior to this in the methylation cycle and to supplement methylfolate and methylcobalamin.
It may be better to give the body more control over the amount of SAM-e it produces rather than force feeding exogenous SAM-e. I haven't seen studies to prove this but I wonder if those who benefit from SAM-e for depression relief may be the same group as those who benefit from methylfolate or methylcobalamin.
The key may be methyl-donation and its role in the management of inflammation and creation of neurotransmitters.
Just some thoughts...

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Offline thereishope

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17732 on: 09/02/2013 17:34:24 »
Hello, I am looking for a P.O.I.S. sufferer the lives in Montreal, Canada; please message me :)

Mod:  Please don't repeat identical (unsolicited) posts in the thread.
I realize you're looking for contacts, but two identical posts in a week won't help
« Last Edit: 09/02/2013 22:51:48 by CliffordK »

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Offline B_Daniel

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17733 on: 10/02/2013 07:19:27 »
Hello, I am looking for a P.O.I.S. sufferer the lives in Montreal, Canada; please message me :)

You just looking to speak with someone in your same city?  (I'm not from montreal btw)
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.

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Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17734 on: 10/02/2013 07:47:04 »
which medcine should i take for inujry testicles .i got hit and i have pain and i think blood is clotted there.generally what medicine should i take?

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Offline B_Daniel

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17735 on: 10/02/2013 07:49:36 »
I'm currently following in the old footsteps of girlwind, michael8028 and a few others on the track of an adrenal and thyroid hypothesis.  Herman helped show me, from the labs I sent him, that my Cortisol is low and that I'm Hypothyroid.  I also sent my labs to Valerie Taylor, the creator of this website: http://adrenalsweb.org/   She went through my labs and said that she also believes that I'm hypothyroid and have adrenal insufficiency. 

From my numbers, there's a lot of information online to support that this may be true, but no scientific studies to confirm it.  I'm currently sending my labs around to a couple endocrinologists to see if any agree with this hypothesis.  Unfortunately, most of my metrics are still within their respective ranges, so despite what seems like a lot of evidence to me, the avg Endo is sure to dismiss there's anything wrong.   

That's all I've got, but I thought it was worthwhile to let ya'll know what I'm up to.  If you have a thyroid panel completed, i recommend contacting Valerie at the website above and getting her thoughts.  She read my labs within just a few minutes over the phone and recommended that i start taking hormone supplements - namely hydrocortisone for the cortisol and T3 for the thyroid.  It's worth noting that these medications aren't to be taken experimentally, because once you start taking them your body will reduce its own production and you may need them for life.  Thus, I'm actively seeking more information now.

Besides Herman's recent suggestions, this forum hasn't discussed Adrenals and Thyroid in a long, long time.  Perhaps someone like B_Jim, Ccconfucius, or another member that's been here a while can chime in with an explanation of why not. 
« Last Edit: 10/02/2013 07:53:10 by B_Daniel »
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.

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Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17736 on: 10/02/2013 08:16:49 »
somebody please help.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17737 on: 10/02/2013 10:54:40 »
which medcine should i take for inujry testicles .i got hit and i have pain and i think blood is clotted there.generally what medicine should i take?
You NEED to go to your doctor. This forum cannot tell you what medicines to take for injury to your testicles. Particularly if you are in pain there could be many reasons including bruising and torsion. Please go to your doctor.

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Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17738 on: 10/02/2013 16:53:13 »
in pak docttors dont undersatnd anything,when i got injury on left one many years ago i keep visiting them and all they did ...nothing

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17739 on: 10/02/2013 17:45:02 »
Correction to my post about my b-vitamin trial. I had actually been taking the b-complex 7 days before I started ALC and for 24 days total. I think that was a bit too long to be taking that much once a night since it seemed I was starting to get odd tiny pain flashes in my joints that I previously didn't have. The past 2 days I stopped taking it and this sensation disappeared but my POIS symptoms still are generally improved.
« Last Edit: 10/02/2013 17:50:07 by Vincent M »
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17740 on: 11/02/2013 07:22:01 »
Correction to my post about my b-vitamin trial. I had actually been taking the b-complex 7 days before I started ALC and for 24 days total. I think that was a bit too long to be taking that much once a night since it seemed I was starting to get odd tiny pain flashes in my joints that I previously didn't have. The past 2 days I stopped taking it and this sensation disappeared but my POIS symptoms still are generally improved.

That's odd. You seem to be well within safe levels of b6. Just check again how much you're taking? Methyl-b12 can cause some nerve tingling but that may not be a bad thing in all circumstances as methylcobalamin / methyl-b12 is often used to treat diabetic neuropathy (nerve damage). It seems that neuropathy itself resembles a tingling sensation (initially) while the repair of nerves that were damaged may also trigger an initial "tingling" sensation.

Here's a paper http://www.sciencedirect.com/science/article/pii/0022510X94902909
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Ultra-high dose methylcobalamin promotes nerve regeneration in experimental acrylamide neuropathy. Tetsuya Watanabe, Ryuji Kaji , Nobuyuki Oka, William Bara and Jun Kimura Department of Neurology, Kyoto University Hospital, Shogoin, Sakyoku, Kyoto 606-01, Journal of Neurological Sciences, Vol 122, Issue 2, April 1994, Pages 140143

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17741 on: 11/02/2013 07:28:53 »
in pak docttors dont undersatnd anything,when i got injury on left one many years ago i keep visiting them and all they did ...nothing
Hi,
I don't believe there are no doctors in Pakistan who can treat an injury to the groin.
It doesn't make sense. In any case, we are not licensed to treat you and cannot recommend a medicine.
When you see people discussing medicines and supplements here they're discussing things that worked for them. Nobody is offering treatment (at least they shouldn't be).

If you just want information about such injuries surely you can google "testicular injuries". Some are very serious and require medical treatment by a doctor.
So far, nobody here has suggested a connection between testicular injuries and POIS so it doesn't appear a relevant discussion fr this forum.

Thanks. 

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17742 on: 11/02/2013 07:34:24 »
Correction to my post about my b-vitamin trial. I had actually been taking the b-complex 7 days before I started ALC and for 24 days total. I think that was a bit too long to be taking that much once a night since it seemed I was starting to get odd tiny pain flashes in my joints that I previously didn't have. The past 2 days I stopped taking it and this sensation disappeared but my POIS symptoms still are generally improved.

That's odd. You seem to be well within safe levels of b6. Just check again how much you're taking? Methyl-b12 can cause some nerve tingling but that may not be a bad thing in all circumstances as methylcobalamin / methyl-b12 is often used to treat diabetic neuropathy (nerve damage). It seems that neuropathy itself resembles a tingling sensation (initially) while the repair of nerves that were damaged may also trigger an initial "tingling" sensation.

Here's a paper http://www.sciencedirect.com/science/article/pii/0022510X94902909
Quote
Ultra-high dose methylcobalamin promotes nerve regeneration in experimental acrylamide neuropathy. Tetsuya Watanabe, Ryuji Kaji , Nobuyuki Oka, William Bara and Jun Kimura Department of Neurology, Kyoto University Hospital, Shogoin, Sakyoku, Kyoto 606-01, Journal of Neurological Sciences, Vol 122, Issue 2, April 1994, Pages 140143
And you're also taking ALCAR which seems to also stimulate nerve growth. Did the tingling persist?
I haven't experienced it myself but I did experience a bizarre desire to chew things (pens mostly) when I took some larger doses of methylb12.

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17743 on: 11/02/2013 17:52:43 »
Interesting. It's possible that the sensation was nerve repair, but since it felt like it would be painful if it intensified I didn't want to risk it. Especially considering I've already gotten an improvement in my symptoms. You're right that I wasn't taking an overdose according to the available data, but I know my body often reacts to substances differently than most. I haven't gotten the sensation today either.

I took 500mg acetyl-L-carnitine this morning and will be taking it morning and night for the next ~ two weeks to see if that was part of my symptom improvement.

I'm used to trying herbs that take effect immediately so I'm still getting used to these longer trials.
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17744 on: 11/02/2013 22:23:56 »
I measure progress over a longer timeframe now. I don't expect overnight results.

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Offline gabin

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17745 on: 13/02/2013 07:00:56 »
http://curezone.com/forums/am.asp?i=1687495 [nofollow] here is an interesting article revealing properties of B3/niacin to fight candida.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17746 on: 13/02/2013 09:49:28 »
http://curezone.com/forums/am.asp?i=1687495 here is an interesting article revealing properties of B3/niacin to fight candida.

Thanks. Interesting link.

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Offline gabin

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17747 on: 13/02/2013 11:41:48 »
Yeap. It's also mentioned that such supplements as olive leaf oil, garlik also contribute to treating candida.
And here is the list of typical candida symptoms:
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What are some systemic symptoms of candida overgrowth?

Symptoms that can be caused by yeast (but may also have other causes) are:
Chronic fatigue, or fatigue in mid-afternoon or after meals
Food cravings, especially for sweets
Depression, brain fog, poor concentration, irritability
Hyperactivity and learning disabilities in children
Loss of sexual desire, dry vaginal area
A reaction or aversion to perfumes, dust, cut grass, tobacco smoke
Allergies or hypersensitivity to foods, chemicals, molds, pollen, perfume, tobacco smoke
Immune impairment, autoimmune disorders
Headaches, stiff neck and back, joint pains
Alternating constipation and diarrhea, or either one
Bladder infections, vaginitis
Sunlight sensitivity, light hurts eyes
An overall feeling of not being well
Bloat and gas. Yeast produces gas and thus bloat, like the gas bubbles that cause the rising of bread.

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17748 on: 13/02/2013 21:21:40 »
For anyone who hasn't visited poiscenter lately there has been some good news. There will almost definitely be a research study relatively soon(not sure how soon, but I'm guessing about a year).

It might make it easier for the researchers if we gather more data on our individual locations and abilities to travel. If you haven't yet you can post your country at this thread: http://poiscenter.com/forums/index.php?topic=299.msg3783#msg3783
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17749 on: 16/02/2013 00:36:54 »
According to Stef, the researcher will be determined around mid-late November this year.
« Last Edit: 16/02/2013 02:21:45 by Vincent M »
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.