[GoingCrazy]

I've been drinking hot chocolate lately and have been noticing some "happy" hormonal release or something.  I suggest some of you guys try it.  Also the last few orgasms i had were non-POIS.

[demografx]

Ragnar, sports_fan, bright n clean, greg44, m_papanikitas and atlgreg, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:

Our new POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

There are 2 ways to get it: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF. Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show the medical world - which often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community. This can help fight the immediate reaction of some: IT'S NOT "ALL IN OUR HEADS"!

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum for nearly 3 years, which has attracted over 150 POIS sufferers worldwide who have posted here, plus over 500,000 page visits. Not bad for a rare malady!

[demografx]

Ragnar, sports_fan, bright n clean, greg44, m_papanikitas, and atlgreg, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: almost 3 years' worth of posts from 150+ Forum members, and an additional 150 POIS sufferers found on the Internet, but not on this forum.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://www.thenakedscientists.com/

for example, I tried
demografx POIS site:http://www.thenakedscientists.com/

and 1,000+ results came up for "demografx" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

[THISFORUMROCKS!]

On the Mayo clinic website I found these following potential treatments for chronic fatigue which had me thinking about their relation to POIS:

[Methylphenidate (Ritalin, Concerta, others). This psychostimulant appears to boost and balance levels of the brain chemicals called neurotransmitters. It's commonly used to treat attention-deficit/hyperactivity disorder (ADHD). One study found that methylphenidate lessened fatigue and improved concentration in some people with chronic fatigue syndrome.

Treatment of depression. If you're depressed, medications such as tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs) may help. Antidepressants may also help improve sleep and relieve pain. Commonly prescribed antidepressants include amitriptyline (Amitid, Amitril), desipramine (Norpramin) and nortriptyline (Aventyl, Pamelor). SSRIs include fluoxetine (Prozac, Sarafem), paroxetine (Paxil) and sertraline (Zoloft).

Cholinesterase (ko-lin-ES-tur-ase) inhibitors, such as galantamine. These drugs improve the effectiveness of acetylcholine, a chemical messenger that is believed to be important for memory, thought and judgment. Galantamine is used in the treatment of Alzheimer's disease, but it has not been found beneficial for chronic fatigue syndrome.]


Is there any general consensus regarding if tricyclic antidepressants and or methylphenidate can have a generally positive effect on POIS sufferers? [?] Please any replies would be helpful so I can have some more info when I talk to my DOC.

Also if there is any consensus can someone please post it to the POIS website. I know it is a bunch of work so I hate to complain, but it appears as though many attempted remedies/failed remedies/suggested theories and "avoiding NE tips" are missing from the POIS website.

Do I just need to perfect my forum searching skills or could other people also benefit from a more in depth summary on the POIS site, if someone is willing to work more on it?   [?]

A few updates: Neither my gluten free nor short term "GAPS diet" seemed to kill pois, though I do continue with the gluten free diet for health benefits []

TAKE NOTE, If not noted already, I find that going to bed on an empty stomach significantly helps avoid NE's []! Anyone else?

I tried "Endorphix" "endorphin amplifying euphoric energizer". It did not kill POIS BUT, did have a positive psychological and physical effect that is difficult to quantify but it did help me make it through the workday which was nice. [] Anyone have an opinion on "Endorphix" whether having read the label or tried it?

And for anyone depressed, ever try eating a pint of ice cream in one sitting? It might make you smile. It kinda works for me sometimes. Just not right before bed. []

Most importantly, what are your favored antidepressant/attention deficit/anti anxiety meds for me to consider?

Happy Holidays ALL [O8)]

[demografx]

...treat attention-deficit/hyperactivity disorder (ADHD).

[and]

Treatment of depression.

Adderall helps my POIS, concentration, and depression.

On antidepressant Cymbalta daily. Not sure about it's impact, except that if I stop it suddenly, sadness becomes more pronounced.

[John21 (OP)]

NE...and here we go again. This time I am affected but not in a large sense so far. One of the first subtle things I notice change is in my eyesight, the circuitry seems to be altered. Another initial change I notice is my knees, and I am amazed that no one else has reported experiencing this... I feel a definite change in them, like a weakness or something. And my mind seems altered and bogged down. In this state I feel very vulnerable to stress, that it can do damage if it is allowed to enter.

I guess I'm not quite free of it yet... []

[demografx]

I hope you have a good and happy Christmas.
--
According some sites, low testosterone cause anxiety,depression and inability to concentrate/cognitive disorders and lethargy.
Demo, has your concentration be improved with T-patchs too ?
I'm very bored with this symptom :/

B_Jim, I get very, very bored with symptoms, like you. It's normal. However I believe that all of us can improve...albeit not completely...to eliminate the boredom.

One thing I did to fight symptom-boredom in several areas of my life was to "push, push, push" this POIS forum...(remember the early days when sometimes it was only you and me and John posting? [] And the mortality rate of new forums is 90%+ so we should take some pleasure in the achievement of our survival!!

For me, sometimes the boredom goes away just by getting involved in someone else's POIS problems. Or to visit a possible POIS donor or researcher. Or simply to cut and paste a picture of Popeye eating POIS-destroying spinach or cut and paste Oprah Winfrey making googly-eyes at "goingcrazy" []

POIS has always been my misery, so I turned it into a hobby!

Also, I FORCED myself to go back to the piano (I didn't play for 5 years).

B_Jim, I think ANY challenge can work for you or me to get out of "boredom" with symptoms. It doesn't have to be difficult, just....different! Simple steps ALWAYS help me, even if it's as small as sending a 10X - repeate []d email to Dr Waldinger

DIFFICULT question about testosterone that you asked, B_Jim. Has it improved my concentration? I can only GUESS that the answer is yes, because I don't know with certainty how to evaluate it "scientifically".

So I just go through each day, SOMETHING has improved my concentration (not just meds, but I'm also working harder to listen, to read, etc. - and even with that, I feel disappointed at times. Some days, I feel lucky just to find our forum website []

[demografx]

I guess I'm not quite free of it yet... []

John, you mirror my sentiments above. You remind me that I've changed the way to look at it...by reminding myself that I can come here to the forum and post my frustration and....people understand!

I've trained myself to accept that "I'm not quite free of it yet", B U T I'm also not living in the old days when I would try to explain POIS to a doctor...only to get severely rejected about POIS: "Go see a psychiatrist!" !!!!!

[Limejuice]

One symptom that occurs immediately after a trigger is weakness and/or numbness in the feet.  For example, I'll wake after an non-emission NE and explicitly know the waking was caused by an NE by sensations in the feet (not by emission).

I've moderately experiemented with this symptom in an attempt to reduce POIS duration by massaging the feet, but without success.  I'm still confident by the mental feeling proceeding O that the issue is chemical/hormonal in the brain. At orgasm I can almost feel it tweak.

[greg44]

Been taking 10mg per day of Valium(Diazepam) for 2 weeks now and have noticed a huge reduction in all symptoms. I decided to try an O to see how my POIS is. O day not much, day 2 I noticed a little bit of elevation in symptoms, but by day 3 and 4 nothing. Back to same as before the O. Overall I'd say I'm 80% cured of the POIS symptoms. Unfortunately I read that you can start developing tolerance towards this drug and its effects will reduce over time but I'm good for now. Something interesting I noticed that I can now get by on 5-6 hours sleep and feel just fine where as before it was nearly impossible due to symptoms being so strong, was forced to sleep 8-9 hours.
What is weird is doctor told me that the Valium should cause me to become severely fatigued but it seems to have had the opposite effect by giving me more energy throughout the day

[POIS-SUFFERER]

Been taking 10mg per day of Valium(Diazepam) for 2 weeks now and have noticed a huge reduction in all symptoms. I decided to try an O to

I also take ATIVAN which is in the same family at 1mg to get me over the bad days of POIS, if I took 10mg I think I would be dead! 2mg and your pretty "high" 3mg and I get amnesia! I am sure they are different in nature the Diazepam and ATIVAN (Lorazepam http://www.drugs.com/lorazepam.html)

But without it I would probably kill myself when in bad POIS!

PS.

[Defsync]

NE...and here we go again. This time I am affected but not in a large sense so far. One of the first subtle things I notice change is in my eyesight, the circuitry seems to be altered. Another initial change I notice is my knees, and I am amazed that no one else has reported experiencing this... I feel a definite change in them, like a weakness or something. And my mind seems altered and bogged down. In this state I feel very vulnerable to stress, that it can do damage if it is allowed to enter.

I guess I'm not quite free of it yet... []

hmm knees... okay im not sure if this is related, but I do notice after an O (ie POIS-mode) that exercise is much more difficult. To me it feels like I become far more sensitive to pain and fatigue

on another note... has anyone looked into chemical castration, or some kinda of nerve snip to prevent O's from ever occurring ever again? Ive been thinking about this lately, although I have been near 100% effective in not having NE's for the last few years, having to take a muscle relaxer every night to ensure this i think is really taking a toll on my body

[demografx]

Defsync, it seems awfully drastic! but one of our POIS posters here claimed that he did exactly what you're suggesting!:
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg191479#msg191479

[demografx]

Rare Illness Appears in US for First Time

Did that get your attention?

It did mine.

It was "front page" AOL News.

No, it wasn't about POIS, but...just wondering...it tells me that POIS does have a nice potential publicity basis to it. And if we can somehow get out there and DO IT, maybe we can get the world's help a little more easily than we are now?

Hellooooooo? Any advertising or publicity experts here??? []
 

[THISFORUMROCKS!]

I think for publicity sake/forum members benefit, we should hold an annual conference/s for discussing POIS theories/findings/symptoms etc.

The main point being to carry the discussion from sufferers online to word of mouth within the general public/media outlets/health care workers.

If actual people gathered in one or more places at once and pamphlets were handed out or whatever, people would eventually come and take notice, local media would take notice; the word would get out.

Media Option 2 is for a POIS sufferer to join a reality TV show, anybody?

And I'm still looking forward to some more youtube videos on the subject, anyone?
If nobody wants to show their identity on video, maybe an actor/actress/friend could be utilized to read a POIS message on youtube?

[THISFORUMROCKS!]

JOHN21,
I notice weak knees starting after NE worsening for a few days till they are at their worst, then gradually improving for a few days after. Its hard to say if it is specifically knee related or just related to overall NE muscle weakness/fatigue in general. TFR!  []

[greg44]

Read through this article related to GABA but left with couple questions.

Just because you consume the food/supplement (L-theanine) that can be used as building blocks for GABA production, What do you have to do to actually get your body to make use of it and increase GABA naturally?

How much tolerance do you build up to GABA enhancer drugs like valium(diazepam) from long term use. Does it reduce by 50% and level out or does it become 100% ineffective?

I've tried ativan(lorezpam) when i had panick attack and damn that stuff is strong, 10 mg valium not even close to the tranquilizer effect the small 2 mg dose of ativan had on me.

Gabapentin(Neurontin) is weak in comparison to valium, Valium much more effective for me.

Cyclobenzaprine I tried that stuff and had some of the worst side effects within 5 days. No idea why my body rejected that stuff so much when I have barely any side effect with the valium.

[Alexia]

I just learned of POIS a few minutes ago.  I just googled nausea after orgasm and it came up in the search results.  The nausea is annoying, but what really freaks me out is that instantaneously after orgasm, I nearly burst into tears, and sometimes actually do!  It's just this overwhelming sense of sadness, and no explanation as to why I feel it!  Anyway, if I don't have orgasms every so often, I get this pent up sexual frustration, but on the other hand I hate having orgasms because of the way I feel afterward, and the fatigue!  I know men sleep after orgasm most the time, but I don't just want to sleep.  I want to hibernate!  I'll be full of energy and perfectly fine until after orgasm, then I am EXHAUSTED!  This is a very frustrating condition and it angers me that the medical profession dismisses it as guilt or repression.  Especially since I know that NOT to be true.  I have no guilt, and I am NOT repressed, yet this is still happening to me!  Now, I DO have OCD, and anxiety and depression are part of the OCD, so I wonder if it's linked to my OCD?  Does anyone else that experiences POIS have OCD or any other psychological conditions?

[demografx]

Alexia, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:

Our new POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

There are 2 ways to get it: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF. Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show the medical world - which often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community. This can help fight the immediate reaction of some: IT'S NOT "ALL IN OUR HEADS"!

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum for nearly 3 years, which has attracted over 150 POIS sufferers worldwide who have posted here, plus over 500,000 page visits. Not bad for a rare malady!

[demografx]

Alexia, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: almost 3 years' worth of posts from 150+ Forum members, and an additional 150 POIS sufferers found on the Internet, but not on this forum.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://www.thenakedscientists.com/

for example, I tried
demografx POIS site:http://www.thenakedscientists.com/

and 1,000+ results came up for "demografx" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.