[demografx]

Demo, I'd just like to mention that self-injection is almost the same risky as 'third-party'-injection  []
In both situation all you (or person performing the injection) need to do in stick to the precautions you've listed above.

May be I take it easier because of a huge expereince of injections on my relatives and my dog  []
Use wool soaked in alcohol, clean the skin thoroughly, don't touch extraneous surface with the needle of the syringe. And ofcourse everything must be disposable.

Excellent. Thank you for pointing that out, gabin!

I would add that it depends on how knowledgeable the "injecters" are. In some cases, I am sure that a self-injecter can be more competent than a poorly trained "3rd party".

But if I had to choose between an experienced nurse or myself, I would ALWAYS prefer the nurse, REGARDLESS of how attractive she is!  []

[Habibou]

But if I had to choose between an experienced nurse or myself, I would ALWAYS prefer the nurse, REGARDLESS of how attractive she is!  []

Hahaha, let s hide it from your wife OMG !!!  []  []

[silverandcol]

I got some Xan-pro from the anti-aging place for like 19 bucks, will report back when it comes in a couple weeks.  I'll probably test one while not in POIS to make sure it doesn't kill me or if there is any allergic reaction.  I find that when I am out of pois i can handle alot of things better like stress, disease, etc, etch.

[demografx]

But if I had to choose between an experienced nurse or myself, I would ALWAYS prefer the nurse, REGARDLESS of how attractive she is!  []

Hahaha, let s hide it from your wife OMG !!!  []  []

Habibou!!!!!! Ssshhhhhhhhhhh!!!!!! [] [] [] [] [] [] [] []

[demografx]

In a discussion with nordnurse, I learned the following:

"Self-injecting deep IM [intramuscular]into the buttock is very difficult because it's awkward.  Requires a 2" long needle, must be done straight in (90-degree angle) -- or it's not deep IM.  

Also, must be done in the upper, outer quadrant of the buttock -- or else there's danger of hitting the sciatic nerve -- which is not a pleasant experience. And can cause permanent injury. "


Thank you, Stefanie (from NORD)!!!

[demografx]

Niacin monitoring -

Today (POIS onset) was 90%+ POIS-free. After my Niacin dose of 500mg NIASPAN, it feels like it jumped to 100%.

Placebo effect? Time will tell.

(Keep in mind that TRT is still my main POIS "cure", with 2.5 years proven 80% efficacy).

[jivetalk]

Just found this info on Niacin - Very Plain Language for simpletons like me to understand.

http://www.vibrantlifenews.com/?tag=niacin

Read with a little skepticism, as he is selling product, but explains a possible Histamine and Niacian relationship.

Just started taking Niacin 100mg tablets. Will try two tabs a day to see if this has any affect.

[Starsky]

So the main problem could be the histamine thats being released while Orgasm? For the vasolidation is the H2 histamine receptor responsible. Perhaps blocking it with cimetidine, ranitidine, famotidine, and nizatidine before orgasm would make a sense?

H2-receptor-mediated vasodilation contributes to postexercise hypotension
Jennifer L. McCord, Julie M. Beasley, and John R. Halliwill

Department of Human Physiology, University of Oregon, Eugene, Oregon

Submitted 5 August 2005 ; accepted in final form 25 August 2005

The early (∼30 min) postexercise hypotension response after a session of aerobic exercise is due in part to H1-receptor-mediated vasodilation. The purpose of this study was to determine the potential contribution of H2-receptor-mediated vasodilation to postexercise hypotension. We studied 10 healthy normotensive men and women (ages 23.7 ± 3.4 yr) before and through 90 min after a 60-min bout of cycling at 60% peak O2 uptake on randomized control and H2-receptor antagonist days (300 mg oral ranitidine). Arterial pressure (automated auscultation), cardiac output (acetylene washin) and femoral blood flow (Doppler ultrasound) were measured. Vascular conductance was calculated as flow/mean arterial pressure. Sixty minutes postexercise on the control day, femoral (Δ62.3 ± 15.6%, where Δ is change; P < 0.01) and systemic (Δ13.8 ± 5.3%; P = 0.01) vascular conductances were increased, whereas mean arterial pressure was reduced (Δ–6.7 ± 1.1 mmHg; P < 0.01). Conversely, 60 min postexercise with ranitidine, femoral (Δ9.4 ± 9.2%; P = 0.34) and systemic (Δ–2.8 ± 4.8%; P = 0.35) vascular conductances were not elevated and mean arterial pressure was not reduced (Δ–2.2 ± 1.3 mmHg; P = 0.12). Furthermore, postexercise femoral and systemic vascular conductances were lower (P < 0.05) and mean arterial pressure was higher (P = 0.01) on the ranitidine day compared with control. Ingestion of ranitidine markedly reduces vasodilation after exercise and blunts postexercise hypotension, suggesting H2-receptor-mediated vasodilation contributes to postexercise hypotension.

[Habibou]

"Thanks for your input.

Thank you for your donation!  Your generosity will help us provide vital programs and services for the nearly 30 million Americans affected by rare diseases."

I just made a 100,00 $ donation to the NORD for POIS  []

[B_Daniel]

I just made a 100,00 $ donation to the NORD for POIS  []

You're the man, Habibou!  Way to benefit everyone here!

[demografx]

[From NORD:]"Thanks for your input.

Thank you for your donation!  Your generosity will help us provide vital programs and services for the nearly 30 million Americans affected by rare diseases."

I just made a $100.00 donation to NORD for POIS  []

Habibou, thank you very much!!!

[demografx]

Research Fund Total: $2,485.00


Please read about it at:
http://poiscenter.com/forums/index.php?PHPSESSID=97a0a767229bfcd7b6822ec05c6c0160&topic=125.0

Then help yourself! by donating here:
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Thank you very, very much, everyone!!

[demografx]

For all our new visitors and friends!


Our new POIS Forum - architectural genius: "daveman" - for detailed subject-by-subject discussion!
http://www.POISCenter.com/forums/index.php


Our 4-year-old POIS thread here at Naked Science Forum will also always remain open for newcomers, for general unstructured discussion, and historical research of the 10,000+ postings here since 2007.


We started a POIS Research Fund to boost our attack on The POIS Monster! Explained here:
http://poiscenter.com/forums/index.php?topic=125.0


We raised $2,150 in just the first 2 weeks, with much more pledged!


And your POIS fund donation is most welcome here:
http://rarediseases.org/about/support/research-donations

[B_Daniel]

Hello fellow POIS sufferers, I haven't been on the forum in a while, and during that time I have found extreme success in possibly curing my POIS 100%.  I remember how in previous posts, animus explained how his POIS came from his spine up into his head.  So during this time I have done several different things, some based upon that information.  I will list what I believe to be the most important thing I have done, to the least important thing I have done.  I say this has cured my POIS 100% because I O'd 5 times about a week and a half ago without any POIS, and just yesterday I have O'd 4 times without any POIS.  Also am sleeping great.  Hopefully this stays strong.  So anyway...

1)  My uncle is a chiropractor and he gave me an adjustment.  First he twisted my neck, the main chiropractic treatment, and than he pressed heavily on my lower spine (cracking it), than pressed heavily on my upper spine (cracking it) with all of his strength.  I haven't had a headache, or inflammation in my head,as I called it, since than.  He told me it is called a cervicogenic headache.
................
The only thing now, especially the last couple of days, instead of the "ache" being in my head that I believe causes POIS as it happens, it feels like it is now in my tailbone.  Now I feel like I have to go to the bathroom almost all the time.  It's really not that bad though.  SO much better than POIS.  This is just a nuisance, feels like a knot down there, and it could possibly just be from running and sports.  So for my POIS and maybe others, it feels as though this is "spine" based.  Possibly a bad alignment of the spine that comes out with headaches and POIS by supposedly blocking circulation.  I will update.

GoingCrazy, I just wanted to come back to your post from a few days ago.  From a NSF member that's as well known and has contributed as much as you have, we really should be placing more emphasis on your "cure" than we currently are.  I think the reason behind this is two-fold.  1) This XN/ Niacin talk has really excited everyone.  2) seeing a chiropractor just seems like such an unlikely cure - but not to say it's not possible.

I guess just keep us updated on your POIS-free status every couple weeks.  If your POIS starts to revert back, and you again have your back cracked and it works again, THAT would be very promising to know it worked more than once.  Thanks for sharing

[lauracostis]

Hello fellow POIS sufferers, I haven't been on the forum in a while, and during that time I have found extreme success in possibly curing my POIS 100%.  I remember how in previous posts, animus explained how his POIS came from his spine up into his head.  So during this time I have done several different things, some based upon that information.  I will list what I believe to be the most important thing I have done, to the least important thing I have done.  I say this has cured my POIS 100% because I O'd 5 times about a week and a half ago without any POIS, and just yesterday I have O'd 4 times without any POIS.  Also am sleeping great.  Hopefully this stays strong.  So anyway...

1)  My uncle is a chiropractor and he gave me an adjustment.  First he twisted my neck, the main chiropractic treatment, and than he pressed heavily on my lower spine (cracking it), than pressed heavily on my upper spine (cracking it) with all of his strength.  I haven't had a headache, or inflammation in my head,as I called it, since than.  He told me it is called a cervicogenic headache.
................
The only thing now, especially the last couple of days, instead of the "ache" being in my head that I believe causes POIS as it happens, it feels like it is now in my tailbone.  Now I feel like I have to go to the bathroom almost all the time.  It's really not that bad though.  SO much better than POIS.  This is just a nuisance, feels like a knot down there, and it could possibly just be from running and sports.  So for my POIS and maybe others, it feels as though this is "spine" based.  Possibly a bad alignment of the spine that comes out with headaches and POIS by supposedly blocking circulation.  I will update.

GoingCrazy, I just wanted to come back to your post from a few days ago.  From a NSF member that's as well known and has contributed as much as you have, we really should be placing more emphasis on your "cure" than we currently are.  I think the reason behind this is two-fold.  1) This XN/ Niacin talk has really excited everyone.  2) seeing a chiropractor just seems like such an unlikely cure - but not to say it's not possible.

I guess just keep us updated on your POIS-free status every couple weeks.  If your POIS starts to revert back, and you again have your back cracked and it works again, THAT would be very promising to know it worked more than once.  Thanks for sharing

TO: "goingcrazy", my brother is a very good chiropractor, but I have never experienced any reduction of pois from being adjusted.  That is not to say that your chiropractic experience is not the cause of your relief from symptoms.

[Starsky]

I think i have some relief from taking Ranitidine, an antihistamine - 300 mg 2h hours before O. And when i take i can last longer.

[daveman]

I think i have some relief from taking Ranitidine, an antihistamine - 300 mg 2h hours before O. And when i take i can last longer.

Sounds interesting, I could use a little "duration" often. My wife would thank you I'm sure!

In general antihistamines haven't help me (as it varies from person to person). Have you found this antihistamine better than others (if you have tried others of course)?

[daveman]

Research Fund Total: $2,485.00


Please read about it at:
http://poiscenter.com/forums/index.php?PHPSESSID=97a0a767229bfcd7b6822ec05c6c0160&topic=125.0

Then help yourself! by donating here:
http://www.rarediseases.org/about/support/research-donations/fg_base_view_p3


Thank you very, very much, everyone!!

Ooops, did you just hear it go DINNNGGGG!


Now it's Research Fund Total: $2,585.00

[Starsky]

I think i have some relief from taking Ranitidine, an antihistamine - 300 mg 2h hours before O. And when i take i can last longer.

Sounds interesting, I could use a little "duration" often. My wife would thank you I'm sure!

In general antihistamines haven't help me (as it varies from person to person). Have you found this antihistamine better than others (if you have tried others of course)?

I think taking Ranitadine + some H1-antihistamine could lessen the impact of histamine. What i found is that Fenugreek is a antihistamine too.

[Starsky]

Ranitidine, under its more commonly used brand names, including Zantac, has been used in the treatment of allergies for some time. It is an antihistamine, but not of the same sort usually prescribed for the treatment of common allergies. Ranitidine is what’s known as a type 2 antihistamine, with separate properties from the type 1 histamine blockers which are more typically used to fight allergy symptoms.

Ranitidine is, in fact, usually prescribed or bought over the counter for the treatment of GERD, or acid reflux disease. However, studies have shown that some of the same properties it brings to bear in the fight against reflux can also be used as a supplement to treat allergies. Sometimes, people complain that the typical OTC allergy remedies don’t quite relieve them of all of their symptoms. In such a case, ranitidine can be a nice addition to the treatment regiment, and may serve to fully eliminate the allergy symptoms.

Those wishing to add ranitidine into their medications should first consult with a physician to ensure the use of the drug will not interfere with any of your doctor’s other medicines. There may also be an increased risk of some of the more common side effects found in antihistamines, such as drowsiness.