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COVID-19
Do we know how important memory cells are in the vaccine response?
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Do we know how important memory cells are in the vaccine response?
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set fair
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Do we know how important memory cells are in the vaccine response?
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26/02/2021 13:51:26 »
The classic explanation we have obout how vaccines work includes something like "so that our immune system knows how to deal with a real infection when it arrives?" But there is also, levels of antibodies remaining at the time of actual infection. Do we know which - memory or extant antibodies are more important with covid? Is there any evidence that memory is involved?
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Re: Do we know how important memory cells are in the vaccine response?
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26/02/2021 19:23:25 »
Both are important.
- But antibodies are (a bit) easier to measure
Antibody levels decline over time, so memory cells are important for long-term protection (provided the virus does not mutate significantly).
- But during an infection, antibody levels rise: antibodies ideally disable virus particles from entering cells; they also mark virus particles for destruction.
- Killer cells identify human cells that have been taken over as virus factories, and shut them down (with extreme prejudice)
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