The Naked Scientists
  • Login
  • Register
  • Podcasts
      • The Naked Scientists
      • eLife
      • Naked Genetics
      • Naked Astronomy
      • In short
      • Naked Neuroscience
      • Ask! The Naked Scientists
      • Question of the Week
      • Archive
      • Video
      • SUBSCRIBE to our Podcasts
  • Articles
      • Science News
      • Features
      • Interviews
      • Answers to Science Questions
  • Get Naked
      • Donate
      • Do an Experiment
      • Science Forum
      • Ask a Question
  • About
      • Meet the team
      • Our Sponsors
      • Site Map
      • Contact us

User menu

  • Login
  • Register
  • Home
  • Help
  • Search
  • Tags
  • Member Map
  • Recent Topics
  • Login
  • Register
  1. Naked Science Forum
  2. Life Sciences
  3. Physiology & Medicine
  4. Drug cures learning disabilities in rats/mice within days - can't find reference
« previous next »
  • Print
Pages: [1]   Go Down

Drug cures learning disabilities in rats/mice within days - can't find reference

  • 2 Replies
  • 4370 Views
  • 0 Tags

0 Members and 1 Guest are viewing this topic.

Offline _Stefan_ (OP)

  • Hero Member
  • *****
  • 814
  • Activity:
    0%
  • Thanked: 1 times
    • View Profile
    • My Photobucket Album
Drug cures learning disabilities in rats/mice within days - can't find reference
« on: 07/07/2008 08:20:20 »
Hi All,

I was listening to a podcasts a few weeks ago and heard that a drug that had already been approved for the treatment of another disease, was tested on rats or mice with learning disabilities. The mice were "cured" within days (something is making me think 24 hours, but just to be safe). This drug now has implications for human learning disabilities, and needs to go through research to test its efficacy on humans.

I can't remember which podcast I heard it on.

If anyone knows about this research and can direct me to some relevant web pages, I'd appreciate it.

Many thanks in advance.
Logged
Stefan
"No testimony is sufficient to establish a miracle, unless the testimony be of such a kind, that its falsehood would be more miraculous than the fact which it endeavors to establish." -David Hume
 



Offline RD

  • Naked Science Forum GOD!
  • *******
  • 9094
  • Activity:
    1%
  • Thanked: 151 times
    • View Profile
Drug cures learning disabilities in rats/mice within days - can't find reference
« Reply #1 on: 07/07/2008 16:20:59 »
Don't know which podcast but these may be relevant...

Quote
March 09, 2001

Scientists Discover Memory-Enhancing Switch

Scientists have genetically engineered mice with enhanced memory that persists until researchers switch it off by removing a drug that controls a gene that encodes a key memory-governing enzyme. With enhanced memory, the mice perform better on memory tests and then revert to normal when the drug is removed.

The achievement, say the researchers who developed the mouse model, offers important insights into the delicate molecular balance by which memory storage is achieved. Although memory-boosting drugs are a long way off, the researchers believe that the work opens new avenues for understanding the molecular basis of memory.
http://www.hhmi.org/news/kandel2.html



Quote
Study Raises Hope for Memory Recovery in Alzheimer's     
 16 July, 2005  14:34 GMT 

Some recovery of memory may be possible in the early stages of Alzheimer's disease, suggests a provocative new study in mice that could help researchers open a two-pronged attack against the mind-robbing illness.
The research shows a mutant protein named tau is poisoning brain cells, and that blocking its production may allow some of those sick neurons to recover. It worked in demented mice who, to the scientists' surprise, regained memory fairly rapidly.

The mice were bred so that eating a certain antibiotic would switch off a gene responsible for producing the bad tau.

Here's the first surprise: As tau production plummeted, the rodents' memory loss didn't just stop -- they regained some memory. It wasn't a full recovery -- dead brain cells can't be brought back -- but after repeated retesting to confirm the results, Ashe concluded that memory function improved to about half the predemented state. Also, neuron death stopped.
http://health.dailynewscentral.com/content/view/1299/63
Logged
 

Offline _Stefan_ (OP)

  • Hero Member
  • *****
  • 814
  • Activity:
    0%
  • Thanked: 1 times
    • View Profile
    • My Photobucket Album
Drug cures learning disabilities in rats/mice within days - can't find reference
« Reply #2 on: 10/07/2008 05:34:03 »
Thanks RD, but I don't think these are what I was listening to about. They are still interesting though.
Logged
Stefan
"No testimony is sufficient to establish a miracle, unless the testimony be of such a kind, that its falsehood would be more miraculous than the fact which it endeavors to establish." -David Hume
 



  • Print
Pages: [1]   Go Up
« previous next »
Tags:
 

Similar topics (5)

I don’t understand physics: does anyone understand physics these days?

Started by charles1948Board That CAN'T be true!

Replies: 110
Views: 3540
Last post 14/02/2021 05:48:42
by evan_au
Find x-intercept and y-intercept for the function: f(x)=9x^2+12x+4.

Started by malyloBoard General Science

Replies: 1
Views: 9570
Last post 10/11/2011 04:31:16
by CliffordK
Why do we find things "cute"?

Started by mike2niner4Board Plant Sciences, Zoology & Evolution

Replies: 10
Views: 15438
Last post 12/07/2009 06:51:15
by Karen W.
How do you use decay constant formula to find decay in excel?

Started by dgt20Board Physics, Astronomy & Cosmology

Replies: 13
Views: 5131
Last post 05/03/2018 15:59:26
by chris
Where can I find the definition of "label claim viscosity"

Started by ratwingBoard General Science

Replies: 1
Views: 4634
Last post 06/09/2011 13:42:37
by damocles
There was an error while thanking
Thanking...
  • SMF 2.0.15 | SMF © 2017, Simple Machines
    Privacy Policy
    SMFAds for Free Forums
  • Naked Science Forum ©

Page created in 0.117 seconds with 39 queries.

  • Podcasts
  • Articles
  • Get Naked
  • About
  • Contact us
  • Advertise
  • Privacy Policy
  • Subscribe to newsletter
  • We love feedback

Follow us

cambridge_logo_footer.png

©The Naked Scientists® 2000–2017 | The Naked Scientists® and Naked Science® are registered trademarks created by Dr Chris Smith. Information presented on this website is the opinion of the individual contributors and does not reflect the general views of the administrators, editors, moderators, sponsors, Cambridge University or the public at large.