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Malaria remains a major global health concern.New, inexpensive, and effective antimalarial agents are urgently needed.Hey! The old Ayurvedal/Chinese medicine is finally joining western orthodox medicine and is already giving very promising results, perhaps thanks to the immigrants from Asia to the USA/UK who are now leading big research labs.Curcumin alone (Turmeric) is being extensively tested for various dreadful human diseases: hundreds of scientific reports and astonishing data...Let's curry on!iko ...these news come from the original Continent: Curcumin-artemisinin combination therapy for malaria.Nandakumar DN, Nagaraj VA, Vathsala PG, Rangarajan P, Padmanaban G.Department of Biochemistry, Indian Institute of Science, Bangalore 560 012, India.Artemisinin and curcumin show an additive interaction in killing Plasmodium falciparum in culture. In vivo, 3 oral doses of curcumin following a single injection of alpha,beta-arteether to Plasmodium berghei-infected mice are able to prevent recrudescence due to alpha,beta-arteether monotherapy and ensure almost 100% survival of the animals.Antimicrob Agents Chemother. 2006 May;50(5):1859-60. But this paper came first: Curcumin for malaria therapy.Reddy RC, Vatsala PG, Keshamouni VG, Padmanaban G, Rangarajan PN.Dept.Int.Med.The Univ.Michigan Med.School, Ann Arbor, MI 48109-0360, USA.Malaria remains a major global health concern. New, inexpensive, and effective antimalarial agents are urgently needed. Here we show that curcumin, a polyphenolic organic molecule derived from turmeric, inhibits chloroquine-resistant Plasmodium falciparum growth in culture in a dose dependent manner with an IC(50) of approximately 5 microM. Additionally, oral administration of curcumin to mice infected with malaria parasite (Plasmodium berghei) reduces blood parasitemia by 80-90% and enhances their survival significantly. Thus, curcumin may represent a novel treatment for malarial infection.Biochem Biophys Res Commun. 2005 Jan 14;326(2):472-4.http://www.sb-roscoff.fr/CyCell/Images/plasmodium1.jpg