How is immune tolerance achieved?

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Offline cheryl j

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How is immune tolerance achieved?
« on: 19/12/2011 21:23:21 »
I believe that before birth and early in childhood the thymus is important in the maturation of T- lymphocytes, and their capacitiy to distingusih between self and non self, but I forget how it works. Are T cells that respond to self-antigens some how eliminated?Or do they never respond to self antigens?
« Last Edit: 20/12/2011 09:42:24 by chris »

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Offline Nizzle

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Re: immune tolerance
« Reply #1 on: 20/12/2011 07:54:07 »
T-cells that respond to self-antigens are indeed also formed and consequently eliminated, but that's about everything I remembered from my education. It had something to do with the "Major histocompatibility complex" but the exact mechanism should be out there on the interweb somewhere..
« Last Edit: 20/12/2011 07:56:17 by Nizzle »
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