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... nobody seems to have been able to figure out how to connect the patterns in any meaningful way to the music itself.
I have no idea how science could legitimately get started on an investigation of the associated phenomena. Neurological reactions to music perhaps?
Emory University neuroscientists went straight to the source and looked at how teenage brains reacted to new music tracks. Kids ages 12 to 17 were shoved into MRI machines and asked to listen to new songs from upcoming artists on MySpace.Three years later, and the researchers looked at the results. The kids' taste in music showed no link to a song's commercial success, but their brain scans told another story. The ventral striatum -- the brain's reward region -- was predictive of a song's future sales.