Depression And Inositol

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Offline Rosa123

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Depression And Inositol
« on: 10/08/2006 07:42:32 »
Small studies have found inositol helpful for depression. Neurotransmitters such as serotonin and acetylcholine in the brain depend on inositol to function properly. Low levels of this nutrient may result in depression. Boosting inositol levels appears to be a promising treatment for depressive conditions.

Blatant advertising removed ! As there is a genuine response the thread will stay unless it does not develop further. I think that's fair !
« Last Edit: 05/09/2006 06:13:32 by Rosa123 »


Offline iko

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Re: Depression And Inositol
« Reply #1 on: 10/08/2006 13:31:54 »
Welcome in this forum (I actually joined few hours ago!)
I attach this abstract and you can see that inositol is not being neglected but actively tested...and it doesn't seem to do much.
Never mind, it's only one report.

Newer treatment studies for bipolar depression.
Gao K, Calabrese JR.
NIMH Bipolar Research Center, Mood Disorders Program, University Hospitals of Cleveland/Case Western Reserve University School of Medicine, Cleveland, OH, USA.
OBJECTIVE: Depressive symptoms of bipolar disorder have more negative impact on a patient's life than manic symptoms. This review focused on the emerging efficacy data for treatments in bipolar depression. METHODS: English-language literature cited in Medline was searched with terms bipolar depression, clinical trial, and trial. Randomized, placebo-controlled trials of newer studies with older agents and all studies with newer or novel agents were prioritized. Open-label studies of novel agents presented at major scientific meetings were also included. RESULTS: Olanzapine, olanzapine-fluoxetine combination (OFC), and quetiapine were superior to placebo in the acute treatment of bipolar depression. Lamotrigine only significantly reduced core symptoms of depression compared with placebo. Pramipexole, a dopamine D2/D3 receptor agonist and omega-3 fatty acids, a polyunsaturated fatty acid, augmentation to mood stabilizer (MS) had superiority to placebo in reducing depressive symptoms. Topiramate augmentation of an MS was equally as effective as Bupropion-SR. Patients treated with an MS responded well to the addition of agomelatine, a melatonin receptor agonist with 5-HT2C antagonist properties. However, inositol and repetitive transcranial magnetic stimulation did not separate from placebo. Lamotrigine and olanzapine, and to a lesser extent, divalproex, are superior to placebo in preventing depressive relapses. All agents were relatively well tolerated. CONCLUSIONS: Olanzapine, OFC, and quetiapine are effective in the acute treatment of bipolar depression. Compared with lithium and divalproex, lamotrigine is more effective in preventing bipolar depression. Larger controlled studies of the other agents in the acute and maintenance treatment of bipolar depression are warranted.
Bipolar Disord. 2005;7 Suppl 5:13-23.
« Last Edit: 10/08/2006 13:34:48 by iko »


Offline ArmenArtist

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Re: Depression And Inositol
« Reply #2 on: 15/09/2006 15:49:42 »
Ive tried inosital for depression.

It was amazing for a few days, but the feeling i got kinda went away, and im bipolar, so i dont know if it was natural or a bipolar mania.