Three teams have improved iPSC stem cell production--which approach is best?

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Offline binnie

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Which of the three new iPSC generating techniques are the best? IPSCs are pluripotent stem cells made by genetically tweaking four so called "Yamanaka" genes in ordinary mature cells. Three teams have increased the haul from from 1% to close to 100%. But which approach is best?

http://www.biosciencetechnology.com/articles/2014/09/nobel-prize-winning-%E2%80%98ipsc%E2%80%99-stem-cell-method-vastly-improved