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Sent to Andrew Daniels:QuoteDear Andrew Daniels,Thank you for an interesting article about the "orgasm flu". I am writing you because there are significant factual errors in the article, which could cause POIS patients to needlessly suffer and to be treated unfairly.The physician you quote, Dr. Resnick, appears to be unaware of the medical literature relating to auto-immune sperm allergies. It is said that 60-70% of men who have had a vasectomy develop an auto-immune reaction to their own sperm, because the physical barrier of Sertoli cells is removed. This is why many vasectomies are not reversible. To quote from a 2007 medical article (linked below),"Certain organs – including the testes and the brain – exist in what is the equivalent of a gated community in the body. Tiny tubes within the testes (in which sperm are produced) are protected by a physical barrier of Sertoli cells. The tight connections between these cells prevent blood-borne infections and poisonous molecules from entering the semen.After a vasectomy, however, the protective barrier is broken and semen mixes into the blood. The immune system recognizes the sperm as invading foreign agents and produces anti-sperm antibodies in 60 to 70 percent of men."Also, the statements "once thought to be a psychological illness" and "researchers estimate that it affects less than one percent of the population" are untrue. POIS was not known to the medical community prior to 2002, so it was never generally thought to be a psychological illness. Likewise, no researchers have attempted to estimate what percent of the population are affected by POIS. This latter statistic may be due to confusion with studies done on post orgasmic headaches.Finally, the symptom list, which is now routinely getting circulated by the media, is not especially accurate. The wikipedia article on POIS is a more accurate characterisation. Specifically, the cognitive problems are severe, and often appear in patients who have no physical symptoms. One of the significant cognitive problems is aphasia -- finding it difficult to formulate thoughts into sentences, having trouble remembering words, and having difficult reading and absorbing information. These symptoms are notable, but transient. They disappear after about a week following orgasm.Could you please amend your article, for the sake of the many people who have this condition and are hoping for treatment and further research?Thank you.Links:http://ihealthbulletin.com/blog/2007/02/13/vasectomy-may-lead-to-dementia-from-autoimmune-brain-damage/http://en.wikipedia.org/wiki/POIS
Dear Andrew Daniels,Thank you for an interesting article about the "orgasm flu". I am writing you because there are significant factual errors in the article, which could cause POIS patients to needlessly suffer and to be treated unfairly.The physician you quote, Dr. Resnick, appears to be unaware of the medical literature relating to auto-immune sperm allergies. It is said that 60-70% of men who have had a vasectomy develop an auto-immune reaction to their own sperm, because the physical barrier of Sertoli cells is removed. This is why many vasectomies are not reversible. To quote from a 2007 medical article (linked below),"Certain organs – including the testes and the brain – exist in what is the equivalent of a gated community in the body. Tiny tubes within the testes (in which sperm are produced) are protected by a physical barrier of Sertoli cells. The tight connections between these cells prevent blood-borne infections and poisonous molecules from entering the semen.After a vasectomy, however, the protective barrier is broken and semen mixes into the blood. The immune system recognizes the sperm as invading foreign agents and produces anti-sperm antibodies in 60 to 70 percent of men."Also, the statements "once thought to be a psychological illness" and "researchers estimate that it affects less than one percent of the population" are untrue. POIS was not known to the medical community prior to 2002, so it was never generally thought to be a psychological illness. Likewise, no researchers have attempted to estimate what percent of the population are affected by POIS. This latter statistic may be due to confusion with studies done on post orgasmic headaches.Finally, the symptom list, which is now routinely getting circulated by the media, is not especially accurate. The wikipedia article on POIS is a more accurate characterisation. Specifically, the cognitive problems are severe, and often appear in patients who have no physical symptoms. One of the significant cognitive problems is aphasia -- finding it difficult to formulate thoughts into sentences, having trouble remembering words, and having difficult reading and absorbing information. These symptoms are notable, but transient. They disappear after about a week following orgasm.Could you please amend your article, for the sake of the many people who have this condition and are hoping for treatment and further research?Thank you.Links:http://ihealthbulletin.com/blog/2007/02/13/vasectomy-may-lead-to-dementia-from-autoimmune-brain-damage/http://en.wikipedia.org/wiki/POIS
What kinds of allergic reactions can people have to semen?People can have localized problems after immediate contact with semen. They can have burning, pain and swelling that can occur for long periods of time. Typically it affects the outer vaginal vault area, though it can also affect the inner vault. Some women describe severe burning and pain, where it feels like 1,000 needles have been injected in them at one time
there may be biological syndromes, whose symptoms are erroneously ascribed to psychological factors ...., By previously consulted specialists, their symptoms were diagnosed as psychological in nature
We're also interested in isolating semen components, not just sperm. []
Quote from: POIS-SUFFERER on 01/02/2011 00:35:48This "gap" we are looking for, or the faulty blood sperm barrier, could this be my Spermatocele http://emedicine.medscape.com/article/443432-overviewThe DR found this a few years back, around the same time my POIS started!If this "buldge" broke or allow sperm to leak into the blood......Thoughts?PS.You just woke up a dormant memory of my "spermatocele" comments from my urologist. It's been years, but I'll check in with him next time about it.
This "gap" we are looking for, or the faulty blood sperm barrier, could this be my Spermatocele http://emedicine.medscape.com/article/443432-overviewThe DR found this a few years back, around the same time my POIS started!If this "buldge" broke or allow sperm to leak into the blood......Thoughts?PS.
Quote from: gabin on 31/01/2011 13:05:50Quote from: afghan666 on 31/01/2011 06:24:06 Last nyt i took I TOOK 100 mG TRAMADOL HCL AND 300 MG GABAPENTIN.THE DOSES ARE A BIT HIGH! anyways i o'd 2 times and then i slept.the timing of ejac had prolonged significantly.good for PE.I woke up ryt now.id nt hav any mental pois symptoms except a lil tiredness. - . Less fatigue. I feel good . I love u all.Demo ![/b]Hell yeah.. i bet you do feel better. Cocaine or heroine can do the job in the same successful way.Taking more Tramadol And Gabapentin Drug Interaction than prescribed by your doctor may cause serious side effects or DEATH.http://www.icq.com/blogs/post/54884 [nofollow]edit - From a physician friend just now received: "I don't know if it is as destructive as cocaine and heroin (which would do the same job), but tramadol is a synthetic opioid. Used very judiciously, that is no big deal. It would be like people who take a Vicodin once in a while when their back goes out. I don't really know if Tramadol 100 mg is a lot or not. Gabapentin 300 mg is not a lot."
Quote from: afghan666 on 31/01/2011 06:24:06 Last nyt i took I TOOK 100 mG TRAMADOL HCL AND 300 MG GABAPENTIN.THE DOSES ARE A BIT HIGH! anyways i o'd 2 times and then i slept.the timing of ejac had prolonged significantly.good for PE.I woke up ryt now.id nt hav any mental pois symptoms except a lil tiredness. - . Less fatigue. I feel good . I love u all.Demo ![/b]Hell yeah.. i bet you do feel better. Cocaine or heroine can do the job in the same successful way.
Last nyt i took I TOOK 100 mG TRAMADOL HCL AND 300 MG GABAPENTIN.THE DOSES ARE A BIT HIGH! anyways i o'd 2 times and then i slept.the timing of ejac had prolonged significantly.good for PE.I woke up ryt now.id nt hav any mental pois symptoms except a lil tiredness. - . Less fatigue. I feel good . I love u all.Demo ![/b]
Quote from: dbfd588 on 31/01/2011 04:52:45I read an article on adrenal exhaustion. It gave symtoms and one was about appetite... Can you provide a link to that article? dbfd, please don't take this personally: the subject has come up often here over the last 4 years by a number of posters. But as I mentioned, we have yet to see good evidence of "adrenal fatigue or exhaustion"."Adrenal Fatigue is not a real medical condition. There is no test that can detect adrenal fatigue.""Tests for adrenal fatigue are not based on scientific facts or supported by good scientific studies."The adrenal fatigue/exhaustion "diagnosis" is often a ruse to sell you health supplements and vitamins....or very questionable "[non]medical consultations". "[Real]doctors are concerned that supplements or vitamins sold as a treatment for adrenal fatigue could hurt you..."Above bold-italicized quotes are from The Endocrine Society and The Hormone FoundationAugust, 2010http://www.hormone.org/Public/upload/Adrenal-Fatigue-Web.pdf [nofollow]
I read an article on adrenal exhaustion. It gave symtoms and one was about appetite...
According to this the study comes from Northwestern University researchers (I don't know if it's valid) :http://www.northwestern.edu/newscenter/stories/2007/02/vasectomy.htmlI found interesting to read Dr. Resnick comments (accurate or not).It seems POIS don't have the symptoms experienced by women who have semen allergy (from a quick research).QuoteWhat kinds of allergic reactions can people have to semen?People can have localized problems after immediate contact with semen. They can have burning, pain and swelling that can occur for long periods of time. Typically it affects the outer vaginal vault area, though it can also affect the inner vault. Some women describe severe burning and pain, where it feels like 1,000 needles have been injected in them at one timeAbout psychological origin of POIS it can come from there:2002 study by Dr Waldinger:Quote there may be biological syndromes, whose symptoms are erroneously ascribed to psychological factors ...., By previously consulted specialists, their symptoms were diagnosed as psychological in nature
Quote from: demografx on 01/02/2011 00:36:46Quote from: Counterpoints on 31/01/2011 18:20:06I don't know where they get..."researchers estimate that it affects less than one percent of the population".I think wikipedia states 1/4 to 1% of the population?Yeah, that's where I saw it too, now that you mention it!!Ya see? With Wikipedia everybody can be an expert! [][]"Experts say". Ohh I like that!
Quote from: Counterpoints on 31/01/2011 18:20:06I don't know where they get..."researchers estimate that it affects less than one percent of the population".I think wikipedia states 1/4 to 1% of the population?
I don't know where they get..."researchers estimate that it affects less than one percent of the population".
Quote from: Counterpoints on 31/01/2011 21:07:46Sent to Andrew Daniels:QuoteDear Andrew Daniels,Thank you for an interesting article about the "orgasm flu". I am writing you because there are significant factual errors in the article, which could cause POIS patients to needlessly suffer and to be treated unfairly.The physician you quote, Dr. Resnick, appears to be unaware of the medical literature relating to auto-immune sperm allergies. It is said that 60-70% of men who have had a vasectomy develop an auto-immune reaction to their own sperm, because the physical barrier of Sertoli cells is removed. This is why many vasectomies are not reversible. To quote from a 2007 medical article (linked below),"Certain organs – including the testes and the brain – exist in what is the equivalent of a gated community in the body. Tiny tubes within the testes (in which sperm are produced) are protected by a physical barrier of Sertoli cells. The tight connections between these cells prevent blood-borne infections and poisonous molecules from entering the semen.After a vasectomy, however, the protective barrier is broken and semen mixes into the blood. The immune system recognizes the sperm as invading foreign agents and produces anti-sperm antibodies in 60 to 70 percent of men."Also, the statements "once thought to be a psychological illness" and "researchers estimate that it affects less than one percent of the population" are untrue. POIS was not known to the medical community prior to 2002, so it was never generally thought to be a psychological illness. Likewise, no researchers have attempted to estimate what percent of the population are affected by POIS. This latter statistic may be due to confusion with studies done on post orgasmic headaches.Finally, the symptom list, which is now routinely getting circulated by the media, is not especially accurate. The wikipedia article on POIS is a more accurate characterisation. Specifically, the cognitive problems are severe, and often appear in patients who have no physical symptoms. One of the significant cognitive problems is aphasia -- finding it difficult to formulate thoughts into sentences, having trouble remembering words, and having difficult reading and absorbing information. These symptoms are notable, but transient. They disappear after about a week following orgasm.Could you please amend your article, for the sake of the many people who have this condition and are hoping for treatment and further research?Thank you.Links:http://ihealthbulletin.com/blog/2007/02/13/vasectomy-may-lead-to-dementia-from-autoimmune-brain-damage/http://en.wikipedia.org/wiki/POISI don't really want to be a pain, but if I see these holes, I'm sure Andrew will do a double check.From:US National Library of Medicine and the National Institute of Healthhttp://www.ncbi.nlm.nih.gov/pubmed/7192697"Vasectomy, therefore, had no demonstrable effect on Sertoli cell function in the rat and our findings support the concept that ligation of the vas does not result in long-term biochemical testicular damage in the experimental animal."Go to:http://www.siteadvisor.com/sites/ihealthbulletin.comperhaps no indication of the validity of the article, but you have to wonder. I haven't read it, have to admit, but I won't go to the site. The article, from what has been said here and the title itself DOES seem to be an extreme case however.60% to 70% of vasectomy cases have sperm antibodies, I had sperm antibodies, but without POIS nor allergy. Even after reversal, I was POIS free for several years, but my case was exceptional for the quantity of time that passed pre-reversal.Most reversals are considered not viable, not because there are antibodies in the blood, but because antibodies bind to the sperm while still within the reproductory system. This happens only in a percentage of those who have antibodies also in the blood. (So of the 60 to 70%, only a percentage of those have antibodies bound to the sperm from within the repro system.And this does not even come close to forcasting POIS, just suggests that fertility would be low or non-viable.POIS requires "the gap".I don't know if Sertoli cells could eventually be responsible for this gap under extended conditions (such as mine for instance - after 22 yrs vasectomy and 15 yrs reversal) or if it's some other mechanism.Hopefully Andrew will just say Ooops and carry on.
Quote from: daveman on 31/01/2011 21:04:12We're also interested in isolating semen components, not just sperm. []Is there anything in semen -outside of sperm - that we should be concerned about? I always thought non-sperm was just a bunch of harmless preservatives []
Your 'holes' are not relevant. He is quoting people saying that we could not become allergic to our own sperm. It is WELL KNOWN that people develop anti-sperm antibodies. It DOES NOT MATTER whether or not these people develop POIS. That was not the point. There can be different types of reactions. One scientific journal paper speculates that such a reaction to sperm is responsible for primary progressive aphasia (PPA).Everything you have pointed out here was obvious to me from the start, and I honestly don't appreciate this 'help', at least in the way that you provided it. I have had discussions with extremely well regarded endocrinologists about the vasectomy reaction.
(wenever getting l - - d or mastrbate).
Quote from: daveman on 01/02/2011 00:58:24Quote from: demografx on 01/02/2011 00:36:46Quote from: Counterpoints on 31/01/2011 18:20:06I don't know where they get..."researchers estimate that it affects less than one percent of the population".I think wikipedia states 1/4 to 1% of the population?Yeah, that's where I saw it too, now that you mention it!!Ya see? With Wikipedia everybody can be an expert! [][]"Experts say". Ohh I like that!Either way, that statistic clearly isn't for POIS. No one has estimated the prevalence of POIS. That is for coital headaches, as I said in my letter.
Quote from: afghan666 on 01/02/2011 08:16:26(wenever getting l - - d or mastrbate).Please change the "intercourse" language and check your spelling just a little. RThis is a Science Forum. Schoolchildren on Science projects visit here.It would also help the people reading your posts if you didn't type in "text message" brief-clipped telegraph style, with words shortened.Thank you very much for your cooperation.