Post Orgasmic Illness Syndrome (POIS)

  • 20075 Replies
  • 6558300 Views

0 Members and 2 Guests are viewing this topic.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15300 on: 10/01/2012 23:24:55 »


Great work, daveman!



*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15301 on: 10/01/2012 23:30:00 »

Anyone know what happened to the original POIS questionnaire database?


Yes, mellivora, we're looking at it now.

Thank you for the reminder!


« Last Edit: 10/01/2012 23:31:38 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15302 on: 11/01/2012 00:44:30 »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15303 on: 11/01/2012 03:23:43 »

Thank you very much Mellivora. With people like you going out of your way and doing real and tremendous work in benefit of POIS we ARE going to get somewhere.

Like both NORDs and HIHs database entry, it takes time to build up on additional information and references. As you say they have to check them out well. And that's why these sources are so respected.

I had a look at the three expert sources listed, and didn't see any direct mention of POIS. But they are in related fields. Let's see if there are people there that actually will work directly with POIS.

We hope to generate events this year that will be worthy of special mention in all of these referential databases.



And I concur and add the following!

« Last Edit: 11/01/2012 03:26:58 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15304 on: 11/01/2012 03:28:48 »
Thank you everyone for the astonishment occurring before my very eyes since wandering here in 2007.

February 18th will be our 5th Year Anniversary!

*

Offline mellivora

  • Sr. Member
  • ****
  • 152
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15305 on: 11/01/2012 10:48:43 »
We have a new TOY!
Are batteries included? Thanks for the time you've put into this Daveman. Sounds great!

I'd like to pledge $100 before the end of March 2012
Great to read that this morning badgerstripe, thanks!!

*

Offline Hoping

  • Full Member
  • ***
  • 57
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15306 on: 11/01/2012 18:17:58 »
"Orgasm Research: Climax in an MRI Machine? Been There, Done That "
http://www.huffingtonpost.com/kayt-sukel/orgasm_b_1193191.html?icid=maing-grid7%7Cmain5%7Cdl12%7Csec1_lnk2%26pLid%3D126089 [nofollow]

demo, this is actually a really interesting article. Throughout the years, there has been talk in the forum about how beneficial it would be to get an MRI during O. The article indicates that there were many test subjects. Is it possible to get a copy of this study? It was conducted in Newark, NJ at Rutgers University. Is anyone living in the area? It would be extremely valuable to get an MRI of a POIS sufferer to compare it with the "normal people" :) in the study. It could be a huge breakthrough examining post-O chemical reactions of POIS sufferers.

*

Offline daveman

  • Neilep Level Member
  • ******
  • 1002
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15307 on: 11/01/2012 20:19:46 »
"Orgasm Research: Climax in an MRI Machine? Been There, Done That "
http://www.huffingtonpost.com/kayt-sukel/orgasm_b_1193191.html?icid=maing-grid7%7Cmain5%7Cdl12%7Csec1_lnk2%26pLid%3D126089

demo, this is actually a really interesting article. Throughout the years, there has been talk in the forum about how beneficial it would be to get an MRI during O. The article indicates that there were many test subjects. Is it possible to get a copy of this study? It was conducted in Newark, NJ at Rutgers University. Is anyone living in the area? It would be extremely valuable to get an MRI of a POIS sufferer to compare it with the "normal people" :) in the study. It could be a huge breakthrough examining post-O chemical reactions of POIS sufferers.

Although this one was for a girl! And I think they were looking at different areas of the brain.

But there must be more than one study that zooms in on the male and his pituitary interactions etc.
How does Murphey do it??

*

Offline jferr

  • Full Member
  • ***
  • 57
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15308 on: 11/01/2012 20:27:07 »
Wow, I have been imaging something like this for quite some time and here it is. Lets find out more about this, It could be so useful.

*

Offline jferr

  • Full Member
  • ***
  • 57
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15309 on: 11/01/2012 21:13:17 »
Guys, As many of you know I have a constant, extremely debilitating POIS, on bad days I freeze with no thoughts like a dementia patient. Paranoia, fog, and physical symptoms..

I took Chlorella, Vitamin C, And ZMA afterwards to go with the niacin I had taken before the orgasm. I recovered much quicker than usual and within a few days I felt more alert and clear than I had felt in a while. I had a purpose in life again. I continued to cycle these products daily and this continued for over a week. My libido was back, Could smile, Got tons done. Have not had one orgasm since and int he past few days I have begun to feel the alertness leaving and as well as my energy. I was thinking maybe placebo but then again I was sustaining the good feelings for over a week. I believe that these medications effected some areas that are deficient and I'm just trying to figure out how to sustain the wellness. I fear that I'm slipping back.

Fellow member, 'Kurtosis', actually was the one who suggested a few of the products to me as he has had consistent relief for a long period of time. I will be trying different herbs to try and sustain some sort of health. Hoping I can come up with a treatment regiment of some kind, the suffering is extensive as you all know first hand.

Best,

Jon.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15310 on: 11/01/2012 21:28:02 »



"Orgasm Research: Climax in an MRI Machine? Been There, Done That "
http://www.huffingtonpost.com/kayt-sukel/orgasm_b_1193191.html?icid=maing-grid7%7Cmain5%7Cdl12%7Csec1_lnk2%26pLid%3D126089



demo, this is actually a really interesting article. Throughout the years, there has been talk in the forum about how beneficial it would be to get an MRI during O. The article indicates that there were many test subjects. Is it possible to get a copy of this study? It was conducted in Newark, NJ at Rutgers University. Is anyone living in the area? It would be extremely valuable to get an MRI of a POIS sufferer to compare it with the "normal people" :) in the study. It could be a huge breakthrough examining post-O chemical reactions of POIS sufferers.


Yes, Hoping, like you, since our early days here I was.....Hoping!.....to see something like this done for male POISers!

An fMRI of POIS!

I just now contacted Dr Komisaruk and we will hopefully get the full paper.

A couple years back, I tried to enlist the support of Dr Komisaruk and his 2 co-authors of their book, "The Science of Orgasm", sadly, no replies.


Wow, I have been imagining something like this for quite some time and here it is. Lets find out more about this, It could be so useful.


From Neuroscience Annual 2011 Conference, Washington, DC

Presentation Title:

An fMRI video animation time-course analysis of brain regions activated during self-stimulation to orgasm in women

Presentation time:

Monday, Nov 14, 2011, 3:00 PM - 4:00 PM

Authors:

 *B. R. KOMISARUK, N. WISE, E. FRANGOS, W. BIRBANO, K. ALLEN;
Dept Psychology, Rutgers, The State Univ. of New Jersey, NEWARK, NJ

Abstract:

 In an fMRI analysis of genital stimulation-induced orgasm, we reported the following sequential activation of multiple brain regions: genital sensory cortex (paracentral lobule) then limbic system regions (insula, anterior cingulate, amygdala, hippocampus) then prefrontal cortex and cerebellum then hypothalamus and nucleus accumbens, followed after orgasm by an overall reduction in activity of all these brain regions. That preliminary analysis was based upon continuous fMRI recording, in which we created regions of interest (ROIs) based on Brodmann’s areas, and represented the activity in each of 80 brain regions (40 on each laterality) as a rising or falling line graph over time (Komisaruk et al, SFN, 285.6, 2010). A more precise insight into the sequence of activation of these brain regions can be gained through dynamic visualization in the form of an animation video that utilizes the same form of data. Consequently, in the present analysis, we have represented the activity of each of 80 Brodmann Area ROIs in its “hot metal” analog, with 10 gradation levels progressing through red, orange, yellow to white. This color code is then applied to each ROI for each 2-sec period during the course of genital self-stimulation before, during, and after orgasm. This is represented in non-dynamic form as the matrix below (a representation of one woman’s orgasm, which is similar to others’), in which each column is an ROI and each row starting from the top down is a 2-sec period. Inspection of the matrix reveals: a) non-uniform sequence of activation of different brain regions leading up to orgasm, b) greater activation in the right hemisphere than the left, c) widespread activation of the brain at orgasm, and d) substantial reduction in brain activity after orgasm. Our analytic animation method utilizes a recurrent loop video. It facilitates an understanding of the interaction and sequential activation of the brain components underlying the gradual development of genital stimulation-induced orgasm.





Disclosures:

  B.R. Komisaruk: None. N. Wise: None. E. Frangos: None. W. Birbano: None. K. Allen: None.
Support: NIH 2R25 GM060826 and the Rutgers University Research Fund.


[Authors]. [Abstract Title]. Program No. XXX.XX. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online.


Great, Rutgers, you've shown us the possibilities and they are exciting!

Now let's do one on the guys!



« Last Edit: 12/01/2012 04:15:20 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15311 on: 11/01/2012 22:10:36 »
Hi all,

As I posted on a poiscenter.com thread a few months ago, encouraged by nordnurse I wrote to Orphanet, the European database of rare diseases in an effort to get POIS included in their database. I've made several follow-ups since then and today we finally have some good news!!

Orphanet now list POIS on their website!!! Daveman and Demo got us listed in the National Institutes for Health Office of Rare Diseases Research database in the U.S. and now we have similar recognition in Europe through Orphanet. Hopefully this will prove a great step in getting POIS to be more acknowledged and recognised by medical professionals and helps give us more credibility than ever.

The listing at this stage is not a huge amount more than the name of our condition. In time, a summary and more details of our condition should appear on the database. Here is a quote from the email I received from Orphanet:

"The summary addition is a complicated process due to the many accuracy controls and it will take time, however, the addition of POIS on Orphanet is the most important part."

The Orphanet listing can be seen here:
http://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=20421&Disease_Disease_Search_diseaseGroup=pois&Disease_Disease_Search_diseaseType=Pat&Disease%28s%29/group%20of%20diseases=Postorgasmic-illness-syndrome--POIS-&title=Postorgasmic-illness-syndrome--POIS-&search=Disease_Search_Simple

I'd like to emphasise that this would not have happened were it not for the advice and encouragement I received from nordnurse. It probably wouldn't have come about if Daveman and Demo hadn't taken the initiative and got us listed in the U.S. either as its that that set me thinking about European databases. And of course it wouldn't have happened without our forums! Our listing on Orphanet is further proof that everyone here can make a difference.

Tell us how ya did it!!

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15312 on: 11/01/2012 22:37:26 »

Request for all - Anyone who hasn't contributed/pledged yet, please do so as it is for our own benefit. The sooner we collect money, the sooner we can be POIS free. Yes, POIS freeeeeeeee!!!!!!   (If you can donate either $5000 or $100, it doesn't matter. What does matter is that we are slowly and slowly reaching our goal. Please pledge/donate as soon as you read this note. Don't wait, otherwise you'll be waiting to cure yourself!)
http://www.rarediseases.org/about/support/research-donations/fg_base_view_p3



Worth repeating!
« Last Edit: 12/01/2012 03:43:29 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15313 on: 11/01/2012 23:11:33 »
Sadly, Willem has been banned as a forum member. We have always made strenuous attempts to not deny any POISer in the world with participation in this Forum. Every ban decision has been made very painfully, but in the end, always contributed to the greater good of our community.

Willem has been recruiting members - for his FOR-PROFIT venture - against agreements we had made. This business-agenda-promoting also is a severe violation of this Forum's rules, its spirit and general ethical forum decorum.

He has demonstrated a blatant lack of respect for the well being of the community and is ONLY interested in his “for profit venture”.

We are in the final stage of very important and real progress, and are working our butts off without profit with the real intention of the community in mind.

More dilution to another profit oriented community will only delay or stop any chance of finding a cure.

Many Thanks, everyone, for your continuing loyalty. His sad, divisive differences coming from profit, and selfish motives will become very apparent to you , and we are very confident that reason - and common sense and most importantly:
G O O D  F A I T H - will prevail in the end.

As always,
Wishing you the best, and only for YOUR interests, not anyone else's.

demografx
and
Daveman
« Last Edit: 20/01/2012 21:27:43 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15314 on: 12/01/2012 00:31:39 »

"Orgasm Research: Climax in an MRI Machine? Been There, Done That "
http://www.huffingtonpost.com/kayt-sukel/orgasm_b_1193191.html?icid=maing-grid7%7Cmain5%7Cdl12%7Csec1_lnk2%26pLid%3D126089



demo, this is actually a really interesting article. Throughout the years, there has been talk in the forum about how beneficial it would be to get an MRI during O. The article indicates that there were many test subjects. Is it possible to get a copy of this study? It was conducted in Newark, NJ at Rutgers University. Is anyone living in the area? It would be extremely valuable to get an MRI of a POIS sufferer to compare it with the "normal people" :) in the study. It could be a huge breakthrough examining post-O chemical reactions of POIS sufferers.


Yes, Hoping, like you, since our early days here I was.....Hoping!.....to see something like this done for male POISers!

An fMRI of POIS!

I just now contacted Dr Komisaruk and we will hopefully get the full paper.

A couple years back, I tried to enlist the support of Dr Komisaruk and his 2 co-authors of their book, "The Science of Orgasm", sadly, no replies.


Wow, I have been imagining something like this for quite some time and here it is. Lets find out more about this, It could be so useful.


From Neuroscience Annual 2011 Conference, Washington, DC

Presentation Title:

An fMRI video animation time-course analysis of brain regions activated during self-stimulation to orgasm in women

Presentation time:

Monday, Nov 14, 2011, 3:00 PM - 4:00 PM

Authors:

 *B. R. KOMISARUK, N. WISE, E. FRANGOS, W. BIRBANO, K. ALLEN;
Dept Psychology, Rutgers, The State Univ. of New Jersey, NEWARK, NJ

Abstract:

 In an fMRI analysis of genital stimulation-induced orgasm, we reported the following sequential activation of multiple brain regions: genital sensory cortex (paracentral lobule) then limbic system regions (insula, anterior cingulate, amygdala, hippocampus) then prefrontal cortex and cerebellum then hypothalamus and nucleus accumbens, followed after orgasm by an overall reduction in activity of all these brain regions. That preliminary analysis was based upon continuous fMRI recording, in which we created regions of interest (ROIs) based on Brodmann’s areas, and represented the activity in each of 80 brain regions (40 on each laterality) as a rising or falling line graph over time (Komisaruk et al, SFN, 285.6, 2010). A more precise insight into the sequence of activation of these brain regions can be gained through dynamic visualization in the form of an animation video that utilizes the same form of data. Consequently, in the present analysis, we have represented the activity of each of 80 Brodmann Area ROIs in its “hot metal” analog, with 10 gradation levels progressing through red, orange, yellow to white. This color code is then applied to each ROI for each 2-sec period during the course of genital self-stimulation before, during, and after orgasm. This is represented in non-dynamic form as the matrix below (a representation of one woman’s orgasm, which is similar to others’), in which each column is an ROI and each row starting from the top down is a 2-sec period. Inspection of the matrix reveals: a) non-uniform sequence of activation of different brain regions leading up to orgasm, b) greater activation in the right hemisphere than the left, c) widespread activation of the brain at orgasm, and d) substantial reduction in brain activity after orgasm. Our analytic animation method utilizes a recurrent loop video. It facilitates an understanding of the interaction and sequential activation of the brain components underlying the gradual development of genital stimulation-induced orgasm.





Disclosures:

  B.R. Komisaruk: None. N. Wise: None. E. Frangos: None. W. Birbano: None. K. Allen: None.
Support: NIH 2R25 GM060826 and the Rutgers University Research Fund.


[Authors]. [Abstract Title]. Program No. XXX.XX. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online.


Great, Rutgers, you've shown us the possibilities and they are exciting!

Now let's do one on the guys! (Both POISers and nonPOISers)




« Last Edit: 13/01/2012 07:23:53 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15315 on: 12/01/2012 04:20:34 »

Guys, As many of you know I have a constant, extremely debilitating POIS, on bad days I freeze with no thoughts like a dementia patient. Paranoia, fog, and physical symptoms..

I took Chlorella, Vitamin C, And ZMA afterwards to go with the niacin I had taken before the orgasm. I recovered much quicker than usual and within a few days I felt more alert and clear than I had felt in a while. I had a purpose in life again. I continued to cycle these products daily and this continued for over a week. My libido was back, Could smile, Got tons done. Have not had one orgasm since and int he past few days I have begun to feel the alertness leaving and as well as my energy. I was thinking maybe placebo but then again I was sustaining the good feelings for over a week. I believe that these medications effected some areas that are deficient and I'm just trying to figure out how to sustain the wellness. I fear that I'm slipping back.

Fellow member, 'Kurtosis', actually was the one who suggested a few of the products to me as he has had consistent relief for a long period of time. I will be trying different herbs to try and sustain some sort of health. Hoping I can come up with a treatment regiment of some kind, the suffering is extensive as you all know first hand.

Best,

Jon.



Sorry if I missed it, but have you had hormonal bloodtesting done?

*

Offline jferr

  • Full Member
  • ***
  • 57
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15316 on: 12/01/2012 09:37:58 »
Not a problem, demografx. Thank you for the response. My bloodwork was as follows:
Name, Result, Reference.

Pregnenolone:           196, (55-455)
Growth Hormone:      4.16, (0.01-0.97) Very High
Free Insulin:              2.2 Micro IU/mL, (1.4-14)

Catecholamines
Norepinephrine:         271 pg/mL, [(70-750) - supine] [(200-1700) - standing]
Epinephrine:              18 pg/mL, [(Undetectable-110) - supine] [(Undetectable-140) - standing]
Dopamine:                 <10 pg/mL, (<30 no postural change) <---? Confused me

Free T3:                    3.4 pg/mL, (2.5-3.9)
Follicle Stimlating Hormone:  1.6mIU/mL, (1.3 - 19.3) Lower End
DHEA:                       3.2 ng/mL, (<13)
Progesterone:            1.07 ng/mL, (0.1-0.8) High
Prolactin:                   6.2 ng/mL, (2.6 - 13.1)
Vitamin B12:              560 pg/ml, (180 - 914)
Folic Acid:                  >20 ng/ml, (3.0-20) Mildly High
Cortisol, PM:              14.6 ug/dL, (3.1 - 16.7)
Total Testosterone:     422 ng/dL, (175 - 781)

Thyroid Tests
TSH:                         2.64 uIU/mL, (0.34 - 5.60)
ESR:                         1 mm/Hr, (0 - 15) Mildly High

CBC
WBC:                        5.8 1000/uL, (4.5 - 11.0)
RBC                          5.33 MiL/uL, (4.20 - 5.80)
Hemoglobin:              14 g/dL, (13.1 - 17.1)
Hematocrit:               43.4 %, (40 - 51)
MCV:                        81.4 fL, (80 - 100)
MCH:                        26.3 pG, (27 - 34) Low
MCHC:                      32.4 g/dL, (31.0 - 36.0)
RDW:                       13.5 %, (11.5 - 14.5)
Platelet Count:          164 1000/uL, (140 - 400)
Lymphocytes:           24.0 %, (17.0 - 40.0)
Neutrophils:              67.2 %, (48.0 - 75.0)
Monocytes:               6.3 %, (0.0 - 14.0)
Eosinophilis:             1.9 %, (0.0 - 5.0)
Basophils:                 0.6 %, (0.0 - 3.0)

CMP
NA:                          139 mmol/L, (136 - 145)
K:                            4.1 mmol/L, (3.5 - 5.3)
CL:                          102 mmol/L, (98 - 107)
CO2:                        28 mmol/L, (22 - 32)
Calcium:                   9.4 mg/dL, (8.4 - 10.2)
Bun:                         16 mg/dL, (7 - 26)
Creatinine:                0.90 mg/dL, (0.60 - 1.30)
eGFR:                       110 mL/mi/1.73 sq m, (>60)
Bun/Creatinine Ratio: 17.8
Glucose:                   88 mg/dL, (70 - 105)
Total Protein:            7.8 g/dL, (6.5 - 8.3)
Albumin:                   4.4 g/dL, (3.5 - 5.0)
Globulin:                   3.4 g/dL
A/G Ratio:                 
Total Bilirubin:           0.4 mg/dL, (0.2 - 1.2)
Alkaline Phos:           85 IU/L, (32 - 92)
ALT (SGPT):             16 IU/L, (10 - 40)
AST (SGOT):            22 IU/L, (10 - 42)

Lipid Profile
Triglycerides:           39 mg/dL, (35 - 160) Mildly Low
Chloresterol:            132 mg/dL, (100 - 200)
HDL:                        42 mg/dL, (29 - 71)
LDL (Calculation):     82 mg/dL, (62 - 130)

Glycohemoglobulin:  5.7, (0.0 - 5.9) Mildly High

Thyroid Tests 2
T3 Uptake:               41.30 %, (32.00 - 48.40)
T4:                          9.69 ug/dL, (6.09 - 12.23)
FTI:                         4.0
Total T3L                  131.12 ng/dL, (87.00 - 178.00)


These tests were taken the morning after orgasm when I'm usually feeling worst. I do want to mention that I lift 4 days a week or so and also take protein after my workout, I'm not sure if that could have affected these results. I'm not sure if there are important things that I did not test for such as other hormones or amino acids, but I tested for quite a bit. Any comments or suggestions are welcomed and appreciated.

Jon.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15317 on: 12/01/2012 17:26:16 »
Thank you, jferr. I would explore with an endocrinologist the possibility of a testosterone-type supplement, only because it has given me such giant relief.

Even when I was given daily testosterone patches that brought my readings into "normal", I asked for and received 50% more. I did this for 2 years and I am just now starting to reduce the testosterone because I show "too much."

Like desensitization, and niacin, TRT is experimental.

BEST WISHES, JFERR!!




« Last Edit: 12/01/2012 22:18:49 by demografx »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15318 on: 12/01/2012 17:53:16 »






From
http://www.capitalfm.co.ke/lifestyle/2012/01/11/are-you-allergic-to-your-own-semen/

Postorgasmic illness syndrome (POIS), or also known as a man’s sad story to a very good happy ending, is a legitimate medical syndrome that has been documented in medical journals since 2002.
It seems that experiencing flu-like symptoms such as runny nose, burning eyes, exhaustion, disordered speech, frightening dreams, swollen lips and feverishness immediately after ejaculating – is not so rare for men after all.
In a 2011 study, Dutch researchers found 87% of the 45 suspected male subjects with POIS experienced the symptoms within 30 minutes after ejaculation. All of the subjects reported clusters of symptoms that were flu-like and involved the head, eyes, nose, throat and muscles – leading researchers to also believe that the male subjects were allergic to their own semen.
When the men were exposed to their own semen through skin pricking tests, nearly 65% of the subjects experienced allergic reactions.
That’s right, they were allergic to their OWN semen.
Researchers believe POIS is caused by a Type-1 and Type-IV allergy, which is triggered as soon as a man experiences an orgasm and ejaculates. Some of the symptoms and discomfort may even last up to a week.
In the study, one of the subjects goes on to explain that because of the severity of his symptoms, the subject’s wife planned to have intercourse only on Fridays so he would have two days to recover before returning to work on Monday.
UK Researchers and doctors have also noted similar symptoms in patients that they’ve treated.
Scientists cannot definitively explain why some men experience allergic reactions to their own semen. However, researchers believe that some men’s semen may be exposed to immune cells, which sets off their immune system.
SOURCE:
Journal Reference:
1. Marcel Waldinger, Marcus Meinardi, Aeiko Zwinderman and Dave Schweitzer. Postorgasmic Illness Syndrome (POIS) in 45 Dutch Caucasian Males: Clinical Characteristics and Evidence for an Immunogenic Pathogenesis. The Journal of Sexual Medicine, April 2011


ARTICLES LIKE THESE ARE NOT THE TRUE OR COMPLETE PICTURE OF POIS AS WE KNOW IT HERE AT THE FORUM, BUT THE GROWING WORLDWIDE PUBLICITY HELPS US GAIN CREDIBILITY AS A MEDICAL CONDITION SO THAT DOCTORS WILL TAKE US MORE SERIOUSLY, WE WILL ATTRACT MORE MEMBERS. AND MORE FUNDING!
« Last Edit: 12/01/2012 23:06:13 by demografx »

*

Offline neilep

  • Withdrawnmist
  • Naked Science Forum GOD!
  • *******
  • 20602
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15319 on: 12/01/2012 21:16:54 »
Dr Sheepie is pleased to see that this thread is still procreating many bountiful replies and comments..and yet......despite the odd controversial circumstance the way that Demografx and the team keep this thread maintained is a tribute to all their incredible work and support that is given to all the members here.
In fact , without all the incredible contributions made by all ewe members there would not be the growing recognition that there is today for POIS..

so...well done to ewe all !!...Ewe are all so damn amazing !!


Dr Sheepie !!!!



[attachment=15837]

Men are the same as women, just inside out !

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15320 on: 12/01/2012 21:24:53 »



Dr Sheepy, whatever would we all dewe without yewe????

Our forums owe you our existence. As most generous friend and most astute mentor........since 2007!

Guys, as a Senior Naked Science Forum member, Neil was right there for us, supporting us, when John21 made his very first post on February 18, 2007!

Thanks A Million, Neil!


« Last Edit: 12/01/2012 21:42:43 by demografx »

*

Offline Vincent M

  • Sr. Member
  • ****
  • 285
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15321 on: 13/01/2012 01:26:49 »
Thank you for your support, neilep.
Taking fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.

*

Offline mellivora

  • Sr. Member
  • ****
  • 152
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15322 on: 13/01/2012 01:45:40 »
Amongst other things, we have started a new thread on the SMF forum documenting the geographic distribution of POIS sufferers. I know we have started similar things before but this new thread is as simple as I can think to make it and I hope it'll get more responses than other attempts in the past. Please log on and add your data if you don't mind. It's here:

http://poiscenter.com/forums/index.php?topic=299.0
« Last Edit: 13/01/2012 13:29:38 by daveman »

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15323 on: 13/01/2012 04:22:50 »


Thanks, mellivora!

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15324 on: 13/01/2012 04:35:46 »
Below is my actual correspondence with a forum member yesterday. His name has been disguised to protect his confidentiality - demo


Since I was a member of Willem's site does it mean I'll be banned if I don't delete my profile there? I didn't realize his site would be a threat to our forums.


No, Anonymous_POISer. Never! Anyone and Everyone should be free to explore anything that might make them feel better.

We just don't want him using OUR free platforms - deceptively - for a profit venture. Several months back, Willem invited me to lunch, pressing me hard to recruit our forum members to his website. I clearly said, "NO!", at lunch, and on subsequent occasions, daveman and I repeated, "No, this goes against the pricinples of a Free Forum." But he was not to be deterred in hunting profits, and continued deceitfully, in spite of assuring us otherwise.

Outright lies and bad faith dealings, I'm sad to report, marred our entire relationship. We're obviously sorry we didn't catch this sooner.

I want OUR MOTIVES dictated by OUR MEMBERS. And not some pharmaceutical company willing to pay "someone like Willem" top $$$$ for info about us (that THEY deem important) so they can sell us "POIS Toothpaste®" LOL...actually that's disgusting, not funny!

YOUR DATA ARE NOT FOR SALE AT NSF AND SMF!

ANONYMOUS_POISer, you are tops in our book!!!

Best,

demo



okay that's a relief, thanks demo : )


You're very welcome, My Friend.
« Last Edit: 13/01/2012 19:20:55 by demografx »

*

Offline neilep

  • Withdrawnmist
  • Naked Science Forum GOD!
  • *******
  • 20602
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15325 on: 13/01/2012 10:43:58 »
Thank you for your support, neilep.


[attachment=15839]
Men are the same as women, just inside out !

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15326 on: 13/01/2012 13:41:38 »





Thank you for your support, neilep.



[attachment=15839]


Still can't thank ewe enough, Buddy Neil!!!!




*

Offline martin88

  • Sr. Member
  • ****
  • 453
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15327 on: 13/01/2012 14:35:31 »
Growth Hormone:      4.16, (0.01-0.97) Very High
I had 0.8 for GH out of POIS. Hope you'll find out why it is so high.

*

Offline Limejuice

  • Sr. Member
  • ****
  • 313
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15328 on: 13/01/2012 15:15:22 »
Just wanted to post progress on exploring desensitization as a treatment. Visited the allergist and she was open to injecting treatments if they were prepared by a trusted doctor. Then contacted Dr Waldinger to see if preparing treatments and shipping them to the US was an option. Awaiting his response.

*

Offline Quasar

  • Sr. Member
  • ****
  • 104
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15329 on: 13/01/2012 16:03:55 »
Not a problem, demografx. Thank you for the response. My bloodwork was as follows:
Name, Result, Reference.

Follicle Stimlating Hormone:  1.6mIU/mL, (1.3 - 19.3) Lower End


Jon, i remember my FSH hormone was also in the lower end!

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15330 on: 13/01/2012 18:39:55 »

Just wanted to post progress on exploring desensitization as a treatment. Visited the allergist and she was open to injecting treatments if they were prepared by a trusted doctor. Then contacted Dr Waldinger to see if preparing treatments and shipping them to the US was an option. Awaiting his response.


LJ, many thanks for the desens update!

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15331 on: 13/01/2012 18:56:58 »



Not a problem, demografx. Thank you for the response. My bloodwork was as follows:
Name, Result, Reference.

Follicle Stimlating Hormone:  1.6mIU/mL, (1.3 - 19.3) Lower End


Jon, i remember my FSH hormone was also in the lower end!


My FSH was in the reference range, normal.


*

Offline Starsky

  • Full Member
  • ***
  • 99
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15332 on: 13/01/2012 19:26:15 »
Just wanted to post progress on exploring desensitization as a treatment. Visited the allergist and she was open to injecting treatments if they were prepared by a trusted doctor. Then contacted Dr Waldinger to see if preparing treatments and shipping them to the US was an option. Awaiting his response.
Limejuice, i think you did not read Waldingers papers. I can tell you ITS NOT A OPTION. Desens treatment is not based on standarized vaccines like for normal allergies. Waldinger dilutes FRESH semen and injects it. If you want really have it done by Walldinger the only option is to move to Holand. I personally would advise you that your allergist gets in touch with Walldinger just too learn how to make the dilutions properly. My allergist said that SCIT is too risky and we chose SLIT, if it will not work we will try provocation-neutralization treatment with injections. 
« Last Edit: 13/01/2012 19:32:24 by Starsky »

*

Offline Limejuice

  • Sr. Member
  • ****
  • 313
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15333 on: 14/01/2012 05:22:07 »
Thanks Starsky

*

Offline jferr

  • Full Member
  • ***
  • 57
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15334 on: 14/01/2012 06:03:43 »
Not a problem, demografx. Thank you for the response. My bloodwork was as follows:
Name, Result, Reference.

Follicle Stimlating Hormone:  1.6mIU/mL, (1.3 - 19.3) Lower End


Jon, i remember my FSH hormone was also in the lower end!

Interesting, Quasar. Were you able to get the levels back to normal? And, If so, What did you to fix it?

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15335 on: 14/01/2012 07:30:09 »


thanks demo (and daveman), for protecting us from commercial exploitation - much appreciated.


Our pleasure!



*

Offline B_Daniel

  • Sr. Member
  • ****
  • 288
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15336 on: 14/01/2012 19:06:12 »
Over the last few pages in the forum, here are the enzymes/ supplements/ vitamins/ treatments that have been suggested:

high grade omega 3s
salmon and seafood
sweet potato
wobenzym
bromelain
papain
multi-enzyme@ nuzyme
spinach
chocolate
B3, B3, B6, B1, B12
vitamin D
olive leaf extract
saw palmetto
garlic
krill oil
vitamin C
zinc
magnesium
zma
tripterygium wilfordil
zymnese
chlorella lecithin
folic acid
spirulina
quercetin

It's difficult for me to separate pie-in-the-sky treatments from the real ones, based on forum posts.  I keep hearing about a page that aggregates all of our treatments but I've never seen it.  And even if there were a list, I'm not sure that's enough.  We desperately need a way to vote on all this stuff.  Kinda like how Amazon reviews products.  Because I'm spending a freakin' fortune on all these supplements that aren't helping me, when that money could/should be going to the NORD fund!
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15337 on: 14/01/2012 19:27:23 »

B_Daniel, is the Polling Center at the other forum a way to begin?

*

Offline B_Daniel

  • Sr. Member
  • ****
  • 288
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15338 on: 14/01/2012 20:12:16 »
Yes I believe that could work!  Unfortunately you couldn't see who rated what so you couldn't reach out to individuals with questions, but it'd be a great start! 

The poll would need to either left open so that other members could add their own treatments to be rated, OR the poll would need to be carefully managed so all suggestions are added.  Plus, the Poll would need to be kept at the top of all the Polls, if possible, so it'd be easy to find.  We need our main pages to be easier to find/ get to than the rest.

I'll attempt to start the poll soon...
« Last Edit: 14/01/2012 20:29:37 by B_Daniel »
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.

*

Offline B_Daniel

  • Sr. Member
  • ****
  • 288
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15339 on: 14/01/2012 20:34:11 »
Yes I believe that could work!  Unfortunately you couldn't see who rated what so you couldn't reach out to individuals with questions, but it'd be a great start! 

The poll would need to either left open so that other members could add their own treatments to be rated, OR the poll would need to be carefully managed so all suggestions are added.  Plus, the Poll would need to be kept at the top of all the Polls, if possible, so it'd be easy to find.  We need our main pages to be easier to find/ get to than the rest.

I'll attempt to start the poll soon...

I tried to make the poll but it won't work - the polling center doesn't have the functionality we need.  To start, a Poller can only click on 1 treatment.  They need to be able to rate all that they've tried, so maybe 30+ in some instances. That's the main problem. 

Second, we need to know how much it helps each person, not just Yes or No.

Yeah, so good suggestion Demo, I thought it might work but it won't   :(
« Last Edit: 14/01/2012 20:35:56 by B_Daniel »
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.

*

Offline daveman

  • Neilep Level Member
  • ******
  • 1002
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15340 on: 14/01/2012 20:57:58 »
Yes I believe that could work!  Unfortunately you couldn't see who rated what so you couldn't reach out to individuals with questions, but it'd be a great start! 

The poll would need to either left open so that other members could add their own treatments to be rated, OR the poll would need to be carefully managed so all suggestions are added.  Plus, the Poll would need to be kept at the top of all the Polls, if possible, so it'd be easy to find.  We need our main pages to be easier to find/ get to than the rest.

I'll attempt to start the poll soon...

I tried to make the poll but it won't work - the polling center doesn't have the functionality we need.  To start, a Poller can only click on 1 treatment.  They need to be able to rate all that they've tried, so maybe 30+ in some instances. That's the main problem. 

Second, we need to know how much it helps each person, not just Yes or No.

Yeah, so good suggestion Demo, I thought it might work but it won't   :(

I am in the process of devising the best method possible to unite various types of information like this into a relational database.

Any surveys and lists that we've had up until now have all been pretty basically manual and with common text entries. So I'm working on organizing a way to have all this information transcripted through a database manager.

Once it's in, then we can start looking for categories and cross referencing  various pieces of data against others.

Also for a quicker fix, while I was browsing around today I found a software add-on to do surveys. I'll be checking it out along with a few more that are kicking around "free".

One of these will accumulate new data, and who knows, might even serve as a portal through which we can transfer the 5 yrs of information we already have.

Sorry for the delay, but I'm working my butt off! :)
« Last Edit: 14/01/2012 21:03:50 by daveman »
How does Murphey do it??

*

Offline B_Daniel

  • Sr. Member
  • ****
  • 288
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15341 on: 14/01/2012 21:01:54 »
It's good to know you're working on it!  Thanks.
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15342 on: 14/01/2012 22:12:38 »

Dave, you have performed one miracle after another here, so I'm not surprised!

I signed up for your walk-on-water lessons, too!

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15343 on: 14/01/2012 23:42:16 »




Individual efforts are (variably) valuable for alleviating [POIS] symptoms but I have no doubt a more methodical research is invariably better if the goal is to identify/confirm the causes and develop "truer" cures.

I'm sure all of us have financial obligations, most of which seem more important than this research fund. It's not my place to ask you to re-evaluate those obligations, but I highly recommend that you perhaps commit to a recurring, automatic donation of small payments, an option NORD offers. Otherwise, I suggest you set up a recurring reminder in your calendars or smartphones (weekly, monthly, bi-monthly, etc.) to manually make a small donation.



Thank you, Ali!

From the POIS funding thread at:
http://poiscenter.com/forums/index.php?topic=168.30



*

Offline daveman

  • Neilep Level Member
  • ******
  • 1002
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15344 on: 15/01/2012 00:05:53 »

Dave, you have performed one miracle after another here, so I'm not surprised!

I signed up for your walk-on-water lessons, too!

I've already found a survey software we can use. I'm going to have to spiff it up a bit, and link it into the forum like the chat software. We can use it for both new surveys, like for niacin etc. AND to recompile older information that's in text form, with help from members entering data.

Soon we'll have data from 5 yrs of effort in a relational database. Something you've wanted for a long time Demo!!
How does Murphey do it??

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15345 on: 15/01/2012 03:23:51 »

               Wow!!!

*

Offline kurtosis

  • Sr. Member
  • ****
  • 360
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15346 on: 15/01/2012 10:52:21 »
Over the last few pages in the forum, here are the enzymes/ supplements/ vitamins/ treatments that have been suggested:

high grade omega 3s
salmon and seafood
sweet potato
wobenzym
bromelain
papain
multi-enzyme@ nuzyme
spinach
chocolate
B3, B3, B6, B1, B12
vitamin D
olive leaf extract
saw palmetto
garlic
krill oil
vitamin C
zinc
magnesium
zma
tripterygium wilfordil
zymnese
chlorella lecithin
folic acid
spirulina
quercetin

It's difficult for me to separate pie-in-the-sky treatments from the real ones, based on forum posts.  I keep hearing about a page that aggregates all of our treatments but I've never seen it.  And even if there were a list, I'm not sure that's enough.  We desperately need a way to vote on all this stuff. 
It's also possible that not everybody's POIS is the same. That we may all have problems but that the root cause may be different or subtly different for some of us.

Of your list here's what worked / didn't work for me. I've no problem in entering this into a survey but getting the survey categories and responses right might be non-trivial :)
Some of these things work well in combination, some can have an effect taken by themselves but it's improved in combinations. It's not as simple as saying 1 thing works or doesn't.

Your list.
high grade omega 3s - Define "high grade". I found the seven seas orange syrup stuff with vitamin C to be the best for me. I also like their "high strength" product.  I tried expensive brands with exotic extraction and purification processes for EPA and DHA and found them to be less effective than the relatively cheap Seven Seas product. The oil worked to reduce inflammations and acne dramatically. Helped with clarity of thought in combination with niacin but NOT taken at the same time where it seemed to reduce the flush.

salmon and seafood - Salmon and Tuna are pretty good. But nothing like the effects of the aforementioned cod liver oil.

sweet potato - ate quite a bit of this. I didn't discern any effects.

wobenzym - never tried it.
bromelain - never tried it.
papain - never tried it.
multi-enzyme@ nuzyme - benefitted digestion issues.
spinach - no discernible effect.
chocolate - helped with concentration but increased acne. Couldn't continue with "chocolate therapy" for that reason.

B3, B3, B6, B1, B12 - B3 (Niacin) and B6 have worked wonders but  the others don't do much for me when taken independently. I take the others at ~100-200% RDA levels (normally in a multi-vitamin) .

vitamin D - by itself, no effect. In cod liver oil I noticed an effect. Whether any of this could be attributed to Vit D, I don't know.

olive leaf extract - no effect.
saw palmetto - never tried it.

garlic - improved stomach issues. Improved energy levels and clarity of thought. Made my breath stink :) I'd certainly recommend POISers to give it a try.

krill oil - worked similar to my favorite orange syrup cod liver oil but at a multiple of the price. This was the only one of the more exotic fish oils that delivered a similar benefit to the cod liver oil product mentioned so I've considered using it more. I'm also interested in seeing if Astaxanthin delivers longer term benefits. The brand I used was superba and I plan on trying it again next month. 

vitamin C - works a treat at improving energy and mental clarity but you need to take it in very large quantities (several grams every day) AND avoid brands which have artificial sweeteners or colorings that can actual impede attentiveness. I'm talking about "sunset orange" colorings, aspartame etc. Do your homework.

zinc - worked in combination with magnesium and b6. Delivered modest improvements to stamina and focus by itself.

magnesium - similar to Zinc. Made me slightly calmer but that may have been a placebo effect.

zma - works for me BUT works best when taken at night rather than in the morning or during the day.

tripterygium wilfordil - never tried it.

zymnese - never tried it.

chlorella - take it with spirulina. Improves mental clarity and in combination with vitamin c (taken within 30 minutes of each other) I can literally feel my POIS symptoms clearing after an O.

lecithin - appears to have some benefit but only in combination with fish oils (or piracetam, see below)

folic acid - take it as part of a multi-vitamin but I noticed a benefit to energy levels and memory when I took it with vitamin C alone, without any other supplementation.

This highlights a general problem. Few people take one supplement by itself. Synergistic effects are likely as nutrients used in one biochemical reaction may cause depletions of others that are replenished by other supplementation. Ratios and complimentary supplementations appear important but are very difficult to capture in surveys.

spirulina - taken with Chlorella. These 2 together really give me a boost of energy and reduce the tension and fuzzy feeling that, for me, define POIS.

quercetin - never tried it.

Other things I've tried
piracetam - gives a very temporary lift if I don't take the other supplementations. Effects can last for over a day if I take ZMA, fish oils, niacin and lecithin. These effects include increased creativity and recollection of past events. Piracetam gave me hope that when we figure out the "cure" it can help POISers glue their brains back together. 

However, piracetam only gives the good and expected results for me when I'm feeling good from the other supplement regime I discussed here and with jferr. Without those supplements, it doesn't give me the boost that many users report.

Tyrosine - gives a short term but powerful boost of energy and focus. For example, I can treble (or more) my average tetris score after about 1g of tyrosine. It's definitely having an effect and I've seen several studies to back this up.

Onto the problems :) Effects fade if I try to take it every day and it makes me feel quite aggressive by the 3rd - 4th day.  It seemed so promising when I took it first and I still think it could be useful as part of a post O protein supplementation regimen. However, I feel I get enough of these proteins in my chlorella & spirulina.

taurine - similar to tyrosine, this gives a short term boost of cognition and energy. I found there's less long term fade and I may restart experimentation with this.

So that's a potted summary of about 5 years of treating my body as a chemistry lab. Anything to get over the dreaded POIS symptoms.

*

Offline daveman

  • Neilep Level Member
  • ******
  • 1002
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15347 on: 15/01/2012 11:38:53 »
Surveys often don't link the user to his vote, so this is a slight touch I'm going to give to ours. Of all the surveys that we will undertake, an important one will be a POIS profile per individual.

Later when we do other surveys, each individual will be linked to his answers so that we can always extract information relative to a certain profile.

The survey programs that are available (free) usually have a limited set of evaluation criteria and usually just say, "to this question 47.3% andswered 'yes' and 52.7% answered 'no', useful, but limited.

But once the database is available, we can use different programs to extract the same answers but related to a specific "user profile", "Individuals that suffer mostly physical symptoms don't respond to niacin, and those with cognitive problems do" for instance.

So it should be interesting.
How does Murphey do it??

*

Offline badgerstripe

  • Jr. Member
  • **
  • 49
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15348 on: 15/01/2012 12:02:44 »
Over the last few pages in the forum, here are the enzymes/ supplements/ vitamins/ treatments that have been suggested:

high grade omega 3s
salmon and seafood
sweet potato
wobenzym
bromelain
papain
multi-enzyme@ nuzyme
spinach
chocolate
B3, B3, B6, B1, B12
vitamin D
olive leaf extract
saw palmetto
garlic
krill oil
vitamin C
zinc
magnesium
zma
tripterygium wilfordil
zymnese
chlorella lecithin
folic acid
spirulina
quercetin

It's difficult for me to separate pie-in-the-sky treatments from the real ones, based on forum posts.  I keep hearing about a page that aggregates all of our treatments but I've never seen it.  And even if there were a list, I'm not sure that's enough.  We desperately need a way to vote on all this stuff. 
It's also possible that not everybody's POIS is the same. That we may all have problems but that the root cause may be different or subtly different for some of us.

Of your list here's what worked / didn't work for me. I've no problem in entering this into a survey but getting the survey categories and responses right might be non-trivial :)
Some of these things work well in combination, some can have an effect taken by themselves but it's improved in combinations. It's not as simple as saying 1 thing works or doesn't.

Your list.
high grade omega 3s - Define "high grade". I found the seven seas orange syrup stuff with vitamin C to be the best for me. I also like their "high strength" product.  I tried expensive brands with exotic extraction and purification processes for EPA and DHA and found them to be less effective than the relatively cheap Seven Seas product. The oil worked to reduce inflammations and acne dramatically. Helped with clarity of thought in combination with niacin but NOT taken at the same time where it seemed to reduce the flush.

salmon and seafood - Salmon and Tuna are pretty good. But nothing like the effects of the aforementioned cod liver oil.

sweet potato - ate quite a bit of this. I didn't discern any effects.

wobenzym - never tried it.
bromelain - never tried it.
papain - never tried it.
multi-enzyme@ nuzyme - benefitted digestion issues.
spinach - no discernible effect.
chocolate - helped with concentration but increased acne. Couldn't continue with "chocolate therapy" for that reason.

B3, B3, B6, B1, B12 - B3 (Niacin) and B6 have worked wonders but  the others don't do much for me when taken independently. I take the others at ~100-200% RDA levels (normally in a multi-vitamin) .

vitamin D - by itself, no effect. In cod liver oil I noticed an effect. Whether any of this could be attributed to Vit D, I don't know.

olive leaf extract - no effect.
saw palmetto - never tried it.

garlic - improved stomach issues. Improved energy levels and clarity of thought. Made my breath stink :) I'd certainly recommend POISers to give it a try.

krill oil - worked similar to my favorite orange syrup cod liver oil but at a multiple of the price. This was the only one of the more exotic fish oils that delivered a similar benefit to the cod liver oil product mentioned so I've considered using it more. I'm also interested in seeing if Astaxanthin delivers longer term benefits. The brand I used was superba and I plan on trying it again next month. 

vitamin C - works a treat at improving energy and mental clarity but you need to take it in very large quantities (several grams every day) AND avoid brands which have artificial sweeteners or colorings that can actual impede attentiveness. I'm talking about "sunset orange" colorings, aspartame etc. Do your homework.

zinc - worked in combination with magnesium and b6. Delivered modest improvements to stamina and focus by itself.

magnesium - similar to Zinc. Made me slightly calmer but that may have been a placebo effect.

zma - works for me BUT works best when taken at night rather than in the morning or during the day.

tripterygium wilfordil - never tried it.

zymnese - never tried it.

chlorella - take it with spirulina. Improves mental clarity and in combination with vitamin c (taken within 30 minutes of each other) I can literally feel my POIS symptoms clearing after an O.

lecithin - appears to have some benefit but only in combination with fish oils (or piracetam, see below)

folic acid - take it as part of a multi-vitamin but I noticed a benefit to energy levels and memory when I took it with vitamin C alone, without any other supplementation.

This highlights a general problem. Few people take one supplement by itself. Synergistic effects are likely as nutrients used in one biochemical reaction may cause depletions of others that are replenished by other supplementation. Ratios and complimentary supplementations appear important but are very difficult to capture in surveys.

spirulina - taken with Chlorella. These 2 together really give me a boost of energy and reduce the tension and fuzzy feeling that, for me, define POIS.

quercetin - never tried it.

Other things I've tried
piracetam - gives a very temporary lift if I don't take the other supplementations. Effects can last for over a day if I take ZMA, fish oils, niacin and lecithin. These effects include increased creativity and recollection of past events. Piracetam gave me hope that when we figure out the "cure" it can help POISers glue their brains back together. 

However, piracetam only gives the good and expected results for me when I'm feeling good from the other supplement regime I discussed here and with jferr. Without those supplements, it doesn't give me the boost that many users report.

Tyrosine - gives a short term but powerful boost of energy and focus. For example, I can treble (or more) my average tetris score after about 1g of tyrosine. It's definitely having an effect and I've seen several studies to back this up.

Onto the problems :) Effects fade if I try to take it every day and it makes me feel quite aggressive by the 3rd - 4th day.  It seemed so promising when I took it first and I still think it could be useful as part of a post O protein supplementation regimen. However, I feel I get enough of these proteins in my chlorella & spirulina.

taurine - similar to tyrosine, this gives a short term boost of cognition and energy. I found there's less long term fade and I may restart experimentation with this.

So that's a potted summary of about 5 years of treating my body as a chemistry lab. Anything to get over the dreaded POIS symptoms.

I know the "my body as a lab" feeling. Thanks for all the information you posted. The one that I KNOW definitely halfs the POIS recovery time is Zinc supplements of 15 - 30 mg daily. Most of my lab stuff centred around food allergies some years ago. My experimentation with Niacin is ongoing and i will post results when i have a few attempts with Niacin. I sometimes go for more than a week without an O just to replenish myself so it may be  a few weeks yet. Thanks for all the work people are putting into this, on here and the other forum  :)

*

Offline demografx

  • Moderator
  • Neilep Level Member
  • *****
  • 8199
    • View Profile
Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #15349 on: 15/01/2012 18:31:59 »




badgerstripe wrote, " Thanks for all the work people are putting into this, on here and the other forum  :) "

And thank YOU, badgerstripe, for your terrific contributions!

Demo