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Nathan, You are one funny dude, you are taking B6 and you expect your blood levels to be normal? Stop testing your serum , it is not accurate and not relevant. Take what I told you to take. And yes you will feel bad on it for a while.
I just want to give my Congratulations to all those who have helped with the nord efforts on pois center. I dont share some people's extreme optimism with regards to this study, but nevertheless i think every one of us supports research and we should be very proud of this pretty major accomplishment together.
Who is currently moderating this forum?
Quote from: Nightingale on 01/03/2013 20:34:48Who is currently moderating this forum?no one: but it seems like the group does not want one, at least not an aggressive one.
The connection between vitamin D deficiency and VDR mutation.http://blogs.scientificamerican.com/observations/2010/06/10/vitamin-d-deficiency-linked-to-genetic-polymorphisms/ [nofollow]
Quote from: kurtosis on 01/03/2013 21:54:00The connection between vitamin D deficiency and VDR mutation.http://blogs.scientificamerican.com/observations/2010/06/10/vitamin-d-deficiency-linked-to-genetic-polymorphisms/This 2010 Lancet study seems to focus on DHCR7/NADSYN1, CYP2R1 and GC genes. I think these genes control transport and biosynthesis of 1,25(OH)_2D, while VDR is downstream. See this link on 1,25(OH)_2D biosynthesis:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675652/figure/fig1/According to this site: http://www.heartfixer.com/AMRI-Nutrigenomics.htm#VDR Taq: Vitamin D Receptor Taq AbnormalityVDR Taq + together with COMT(-/-) causes low dopamine in general, and needs methyl donors..I recently read some articles questioning some of Dr.Amy's claims:http://web.mit.edu/london/www/cbs.htmlthat suggestsUrinary ammonia test is unreliableUrinary taurine test is unreliableglutathione deficiency may be caused by SOD1/2/3 mutation.Kurtosis, have you done any blood test on glutathione? I wonder if there is a way to directly measure it. Thanks!I am rethinking what I have learned so far, A1298C mutation seems quite pronounced. VDR bsm and taq (++) seems to be not very rare in general population.
The connection between vitamin D deficiency and VDR mutation.http://blogs.scientificamerican.com/observations/2010/06/10/vitamin-d-deficiency-linked-to-genetic-polymorphisms/
Yasko, A. Arrow , et al. (1993) Acid Stable End Blocked Nucleic Acids and Therapeutic Uses Thereof. US Patent