[sebastiano]

Hello friends, Just an update of my POIS status and Gaurav's.  We both are cured from the long time and POIS not bounce back on us. 

Also, as I mentioned in my earlier mails, along with my Dr( who has cured me), we have identified few patients in big neurology hospital and taken their views of their disease after orgasm. Interestingly, as i mentioned earlier, we got around 20 patients who are suffering from POIS and they are on the assumption that they are suffering from migraine.

Further, from the past several time, I and my doctor experimenting various techniques to decrease / cure POIS. Accordingly, we have got this new technique, if do this, the symtoms of POIS will come down in just two hours.        The technique is as follows. 

After orgasm, if you feel, you are attacked with POIS, after one or two hours after orgasm, please close your left nostril and breath only in right nostril for 30 minutes.    You would find a substantial decrease in the POIS symtoms.  If in the next day, if symtoms not fully cured, do the same thing in morning and at night only for 30 minutes. See the results. 

Requesting to give the feed back so it would help to know whether POIS in India is same as you are suffering. 

Please don't neglect as here we find lot of good results from this technique. I will explain the logic behind this if any good result found .

I've been using this technique for long time with good results.It' a yoga technique.

1) If you feel weak or tired you have to close your left nostril and breath with your right nostril.You are warming yourself

2) If you have migraine you have to close your right nostril and breath with your left nostril.You are cooling yourself.

I never have a migrain, but I feel weak after orgasm so I use tecnique number 1.And I drink hot water to raise my temperature (which lowers after orgasm)

sounds quite stupid that breathing through left or right will cool down or warmer you up. Not logical at all.

Your words sound stupid. You don't konw anything about yoga. And you think POIS is due to gluten!!!

Explain to me how left and right nostrils are NOT connected.

explain me why POIS syntomps appear after orgasm and not after eating gluten

[vik1379]

Nathan, your pois treatment did not work for Gaurav. Gaurav needed a different treatment (from your previous posts)... What treatment did Gaurav use to cure pois?

Thanks

As I mentioned earlier, my treatment not work for Gaurav. He cured by removing his Wisdom Teeth.
Requesting to try the above mentioned breathing exercise, as we are finding good results here for other persons.    It is very interesting. Pls try and tell yes or no, whether by doing that there would be any benefit or no.   

Even though I am cured, for the benefit of others, I along with my doctor, are engaged in findings cure for others with no money mind.  Pls I want response.  Pls send atleast half an hour and reply Yes or NO.

I tried it yesterday - no results

[johanstefansson]

Hello friends, Just an update of my POIS status and Gaurav's.  We both are cured from the long time and POIS not bounce back on us. 

Also, as I mentioned in my earlier mails, along with my Dr( who has cured me), we have identified few patients in big neurology hospital and taken their views of their disease after orgasm. Interestingly, as i mentioned earlier, we got around 20 patients who are suffering from POIS and they are on the assumption that they are suffering from migraine.

Further, from the past several time, I and my doctor experimenting various techniques to decrease / cure POIS. Accordingly, we have got this new technique, if do this, the symtoms of POIS will come down in just two hours.        The technique is as follows. 

After orgasm, if you feel, you are attacked with POIS, after one or two hours after orgasm, please close your left nostril and breath only in right nostril for 30 minutes.    You would find a substantial decrease in the POIS symtoms.  If in the next day, if symtoms not fully cured, do the same thing in morning and at night only for 30 minutes. See the results. 

Requesting to give the feed back so it would help to know whether POIS in India is same as you are suffering. 

Please don't neglect as here we find lot of good results from this technique. I will explain the logic behind this if any good result found .

I've been using this technique for long time with good results.It' a yoga technique.

1) If you feel weak or tired you have to close your left nostril and breath with your right nostril.You are warming yourself

2) If you have migraine you have to close your right nostril and breath with your left nostril.You are cooling yourself.

I never have a migrain, but I feel weak after orgasm so I use tecnique number 1.And I drink hot water to raise my temperature (which lowers after orgasm)

sounds quite stupid that breathing through left or right will cool down or warmer you up. Not logical at all.

Your words sound stupid. You don't konw anything about yoga. And you think POIS is due to gluten!!!

Explain to me how left and right nostrils are NOT connected.

explain me why POIS syntomps appear after orgasm and not after eating gluten

Dont act stupid please, take a look at your nose and tell me the difference between your right and left nostril. There is no difference, so please stop posting nonsence here. Your unscientific attitude is what keeps scaring doctors away from this subject.

Gluten would cause malnutrition and lack of vital vitamins, hence severe problems upon ejaculation since this consumes a lot of energy and vitamins etc.

[sebastiano]

Hello friends, Just an update of my POIS status and Gaurav's.  We both are cured from the long time and POIS not bounce back on us. 

Also, as I mentioned in my earlier mails, along with my Dr( who has cured me), we have identified few patients in big neurology hospital and taken their views of their disease after orgasm. Interestingly, as i mentioned earlier, we got around 20 patients who are suffering from POIS and they are on the assumption that they are suffering from migraine.

Further, from the past several time, I and my doctor experimenting various techniques to decrease / cure POIS. Accordingly, we have got this new technique, if do this, the symtoms of POIS will come down in just two hours.        The technique is as follows. 

After orgasm, if you feel, you are attacked with POIS, after one or two hours after orgasm, please close your left nostril and breath only in right nostril for 30 minutes.    You would find a substantial decrease in the POIS symtoms.  If in the next day, if symtoms not fully cured, do the same thing in morning and at night only for 30 minutes. See the results. 

Requesting to give the feed back so it would help to know whether POIS in India is same as you are suffering. 

Please don't neglect as here we find lot of good results from this technique. I will explain the logic behind this if any good result found .

I've been using this technique for long time with good results.It' a yoga technique.

1) If you feel weak or tired you have to close your left nostril and breath with your right nostril.You are warming yourself

2) If you have migraine you have to close your right nostril and breath with your left nostril.You are cooling yourself.

I never have a migrain, but I feel weak after orgasm so I use tecnique number 1.And I drink hot water to raise my temperature (which lowers after orgasm)

sounds quite stupid that breathing through left or right will cool down or warmer you up. Not logical at all.

Your words sound stupid. You don't konw anything about yoga. And you think POIS is due to gluten!!!

Explain to me how left and right nostrils are NOT connected.

explain me why POIS syntomps appear after orgasm and not after eating gluten

Dont act stupid please, take a look at your nose and tell me the difference between your right and left nostril. There is no difference, so please stop posting nonsence here. Your unscientific attitude is what keeps scaring doctors away from this subject.

Gluten would cause malnutrition and lack of vital vitamins, hence severe problems upon ejaculation since this consumes a lot of energy and vitamins etc.

You are ignorant like a goat.You have only one neuron and it doesn't work!

If you have a chronic and severe illness, you feel bad all the time and of course you feel bad after orgasm (which consumes a lot of energy) !!!!!! What a discovery!
This is not POIS !!!!  POIS is about people that have good health (doctors and exams can't find anything wrong) You are in the wrong forum.
You don't believe breathing techniques can increase or decrease body temperature?
Read!!!!

http://www.sciencedaily.com/releases/2013/04/130408084858.htm [nofollow]

"A  team of researchers led by Associate Professor Maria Kozhevnikov from the Department of Psychology at the National University of Singapore (NUS) Faculty of Arts and Social Sciences showed, for the first time, that it is possible for core body temperature to be controlled by the brain. The scientists found that core body temperature increases can be achieved using certain meditation techniques (g-tummo) which could help in boosting immunity to fight infectious diseases or immunodeficiency.

Published in science journal PLOS ONE in March 2013, the study documented reliable core body temperature increases for the first time in Tibetan nuns practising g-tummo meditation. Previous studies on g-tummo meditators showed only increases in peripheral body temperature in the fingers and toes. The g-tummo meditative practice controls "inner energy" and is considered by Tibetan practitioners as one of the most sacred spiritual practices in the region. Monasteries maintaining g-tummo traditions are very rare and are mostly located in the remote areas of eastern Tibet.

The researchers collected data during the unique ceremony in Tibet, where nuns were able to raise their core body temperature and dry up wet sheets wrapped around their bodies in the cold Himalayan weather (-25 degree Celsius) while meditating. Using electroencephalography (EEG) recordings and temperature measures, the team observed increases in core body temperature up to 38.3 degree Celsius. A second study was conducted with Western participants who used a breathing technique of the g-tummo meditative practice and they were also able to increase their core body temperature, within limits."



Be humble! You can't teach anything .You have to learn.

[MrVat7]

Does anyone know what are the side effects of taking high testosterone dosage (250 mg a week ) ? Can it cause development of Breasts in male?

[johanstefansson]

Orgasm saturday, hardly any symptoms. Used niacin before and after. Dont know if it was what worked but hey very nice not getting sick at all. Could also be the fact it was quite some time since last O.

I have read that niacin has been used to counterfeit depression and addiction, any comments on it?

Please keep posting guys!

[demografx]

[Former Moderator visiting periodically]

It has been interesting reading the comments about testosterone. I was brought up vegetarian and fed loads of soya meat-substitutes by a well-meaning mother, which I think is partly responsible for my condition, because soya increases estrogen levels.

I have scheduled a visit with an endocrinologist in 2 weeks and am going to have my T levels tested. If need be I will then go onto testosterone supplements. I will also move onto a full nutrition supplement.

I have suffered from this f^%king disorder for 18 years now, and have achieved nothing more than symptom reduction and management, so if it works for me hopefully will work for others. Will keep you posted.

My years-old similar visit to my endocrinologist changed my life!

[MrVat7]

Can high dose of testosterone cause gynecomastia ?

[LegatoMan]

Wow. After almost 6 years of desperately sifting through the internet for information, I can't believe I only just found this Forum today.

I wish I could write down all of the details of my odyssey (doctors, treatments, experiments, etc) ... but unfortunately the brain fog is too strong right now for me to compose a decent text here..

All I can say right now, is, I've been bouncing back and forth between doctors for many years, and only one of them actually BELIEVED my symptoms were real. He is an endocrinologist, and he's run more blood tests on me that I can number, we haven't found ANYTHING yet, but at least he believes me. And that means so much, I can't even tell you.

I have the deepest sympathy for all of you who are suffering from the same disease. It has cast a dark, dense shadow over all aspects of my life in the last 5 1/2 years, personally and "professionally", physically and mentally, yadda yadda yada.... you KNOW what I'm talking about!!

I would love to answer some questions, if you have any. Or spend some time talking to anyone who still frequents this thread. Seeing that it's already 780 pages long is kinda intimidating, I must admit I haven't read everyone's stories and aquainted myself with them...

Just a little background information about me:
I am 23 years old now, and my symptoms started shortly after my 18th birthday. I live in Germany, and I'm a musician.

My mental symptoms include:
Brain fog, fatigue, depression, lack of creativity.

Sexual symptoms are:
low libido, testicular and penile atrophy, (what feels like) varicoceles in my seminal cords, and (what feels like) scarring of the erectile tissue, making it difficult to maintain an erection (you can forget condoms)...

...and of course, the horrible crash after an orgasm, lasting for at least 3-4 days. It takes me 7 days of abstinence, exercise, exposure to sunlight, and a clean (mainly raw vegan) diet to achieve a relatively functional state of being. But it's STILL never 100%, like I used to feel. And a side-effect of being so clean and abstinent for so long, is that, well, some of my libido DOES come back! And then if I masturbate or have sex, the whole cycle starts again. It's a vicious cycle that I'm sure you're all well aware of.

Other, perhaps unrelated symptoms:
Digestive: loose stools, diarrhea, urgency to go to the bathroom, gas and bloating, and acid reflux/sulphur burps
Vocal: I'm a singer, and I've noticed a pronounced reduction in vocal cord closure. What this means: I am "hoarse" in certain areas (ranges) of my voice, I've lost range on both ends, I've had to re-learn my intonation, and it just makes singing very uncomfortable.

So... that's about it for now. When I get some mental clarity back, I'll attempt to read more posts and get to know you more!

[RD]

... exposure to sunlight ...

There are systemic diseases which are made worse by exposure to sunlight (UV light),
e.g. Lupus , dermatomyositis , porphyria.

[Thapelo]

Does anyone know what are the side effects of taking high testosterone dosage (250 mg a week ) ? Can it cause development of Breasts in male?

MrVat7,
i study medicine, and there are numerous side effects of taking high testosterone, ill ask my endocrinologue for you if he can make a list of the effects. taking high testosterone does not cure pois, says my doctor... but ill ask for the side effects

Lars

[LegatoMan]

... exposure to sunlight ...

There are systemic diseases which are made worse by exposure to sunlight (UV light),
e.g. Lupus , dermatomyositis , porphyria.

Well, then I certainly don't have any of those!

[mellivora]

Hi everyone,

I found this thread after realizing I had POIS. It was getting worse for me over time and now that I have a girlfriend my symptoms were really showing up.

I would feel tired/achy/grumpy for a day or two after sleeping with her, and the more we slept together the worse it got. It felt like a hangover from a really bad night of drinking.

I tried taking more vitamins, changing my sleep/exercise routines/, not watching porn anymore, etc., which all helped but never solved the problem.

Finally what worked for me was getting off of gluten. My POIS that I've had for many years vanished!

I just wanted to log in and share my experience in case it helps anybody searching for an answer. I know I got to the point where I was willing to try anything that might have helped, so here's another thing to try.

Good luck to everyone.

Sincerely,
Seth

Hi Seth,
Thanks for sharing your experience. How long after starting your gluten-free diet did you notice an improvement in your symptoms and how long after starting the diet until  you realised your symptoms  had vanished completely?
Mel

[fornicationDENIED2]

Does anyone know what are the side effects of taking high testosterone dosage (250 mg a week ) ? Can it cause development of Breasts in male?

MrVat7,
i study medicine, and there are numerous side effects of taking high testosterone, ill ask my endocrinologue for you if he can make a list of the effects. taking high testosterone does not cure pois, says my doctor... but ill ask for the side effects

Lars

No offense mister, but high testosterone would be 400mg or more a week .

I am going to cover basic information only because I am in a hurry, I will explain in more detail later.

Gyno is associated with exogenous thanks conversion of testosterone to estrogen(ESTROGEN is the catalyst of 80% of the nasty side effects from testosterone) and also keep in mind that conversion to estrogen will be greater because of the huge testosterone peak after injection even at TRT doses since natural production  is much lower and testosterone levels fluctuate (higher in morning lower at night). There are drugs called aromatase inhibitors (inhibiting the enzyme aromasin from converting testosterone to estrogen) which take care of this, and the best one by far is aromasin particularly for having less side effects like no reduction in IGF-1. These drugs should be taken in low dosages to prevent estrogen going down too low, which causes the majority of the scary side effects like osteoporosis, lower libido etc. that are never explained why they occur (generally speaking of course) .
I recommend to stay away from letrozole and arimidex if you can afford aromasin but I will explain why later. Send me PM if you want.

As for infertility, if you desire to restore it you can use Pregnyl (REAL HCG, not the crap at Walmart) which acts as LH in the body restoring testicular function and combine it with aromatase inhibitors and SERMS (Letrozole) to reduce estrogen and restore the hypothalamus pituitary gonadal axis quickly, restoring natural testosterone production and spermatogenesis.

There are also drugs that prevent conversion of testosterone to DHT if prostate issues are occurring.
As for non estrogen/DHT related side effects like increased blood cell count are completely manageable at 250 mg.

[fornicationDENIED2]

Personal ancedotes: TRT has cured my POIS.

I had mentioned earlier I was put on corticosteroids, these inhibited testosterone production, reduced TSH, reduced conversion of T4 to T3 and made me hypothyroidal apart from somehow increasing my estradiol to 3 digits and due to estrogen increase my prolactin went up to high yet inside the stupid range apart from all symptoms of Cushing syndrome. I am on aromasin and 200mg a week of testosterone cypionate, androgel is useless because it comes in contact with fat cells were aromatase enzymes are concentrated the most causing high estrogen. My IGF1 levels have increased, the anti inflammatory effects of testosterone have put crohns disease in remission and helping in the regeneration of the intestinal walls (since IGF1 is essential for the regeneration of my intestinal walls apart for some bonus immunomodulating effects). I am almost 100% POIS free and gaining 8 pounds of muscle every two months(a normal healthy human requires a year minimum to build all that muscle) which is helping my muscular atrophy greatly.  I will eventually come off with a Pregnyl and aromasin cycle because of my age(18).

Most recent labs:

estrogen <50 pg/mL
total testosterone 1721 ng/dL
Free testosterone 382.1 pg/mL

Testosterone is higher than it should at 200mg thanks to aromasin.

[acronym]

Personal ancedotes: TRT has cured my POIS.
......

FD, that's a pretty high dosage of T. Is your doctor prescribing you this amount or are you undertaking this on your own?
the cypionate ester if I remember right has a short half life, so you will need more frequent injections,but that is still a high dose, from a 'conventional' medical perspective. I am on Testosterone Ethanate (longer half life) and am currently at 100mg a week, which is higher than what my doctor wanted, but I feel better for it and have never scored high on T blood tests (with just T injections).

When I was originally put on T shots it was a once a month injection, and that screwed me up - way too much fluctuation, and my pois got worse. I split my doses up and increased the amount I was taking and I was a lot better for it. I did this then told my doctor and he reluctantly went along with it. The official doctors drug manual for Sustan250 for instance still recommends once a month injection. I found I was struggling by day 18 and when I had blood tests on say around day 10-12, my levels were at 1/4 of the normal range.  I have experimented with T by taking high doses at your levels and had mixed results. In the cooler months of the year I felt better for it and put on weight and my pois was less. In the warmer months of the year it seemed to make no difference. I had increased stress levels & more hair loss though. Its weird and very very frustrating. The only time I put on weight is in the cooler months. I still lose weight in the summer even during the times I was on 100mg+/week.

I took an OTC anti aromatase + also herbs. I did not experience any gyno, but some people are less susceptible. I have low body fat levels.  When I trialled 200mg/week, I took Clomid when I dropped my T intake back to lower levels, and I cant say I noticed anything, but then I did not crash so it could have been doing its job well. I did not get any T blood tests to verify my levels at this time.

I had good results with the herb TongkatAli which boosts LH ( and maybe also FSH levels) and testosterone a number of years ago. I have since tried it a few more times but have been disappointed. This is a potent herb and grown only in limited part of the word and there is a lot of bogus/weak product out there now being marketed. I feel this would be a good herb for some pois'ers to try. Unfortunately I cannot recommended a good source. It very expensive now too. I have asked a couple of my doctors about trying Clomid or Pregnyl to increase my natural T levels but they are not interested.

I also experimented by taking Nandrolone as well as Testosterone (lower dose - 60mg/week) and found taking the two together to be more potent at the equivalent dose of just testosterone. (blood test for T levels showed me at the top end of normal for the first time in my life) My pois was much better too, however like the comment I made earlier about T being more beneficial for me during the cooler months, it is the same story when I take T & N, alas.  My pois has always been less in the cooler months even before I took any supplements. I can't remember anyone else here saying there was a seasonal component to pois. Around the same time I got pois I got chemical sensitivities + food intolerances. I tested at very high on IgE levels (related to allergies) and strong reaction to many grasses (even though I don't get hayfever anymore - that stopped when I got pois). I wonder if the grasses which are high except in the cooler months are impacting badly on my immunity/endocrine system...even though I don't have hayfever.

I cannot comment on pois in relation to my IGF-1 levels, as I have never had a good IGF-1 reading. I have below normal IGF-1. Same with DHEA.  There certainly could be a connection though.

[MrVat7]

To all TRTers .. have you experienced any minor/major side effects ?

[acronym]

To all TRTers .. have you experienced any minor/major side effects ?

Increased stress levels during the warmer months of the year but less so during the cooler months. More assertiveness & confidence & libido & strength then (mid autumn - mid spring). Some hair loss. Fat loss - all over including face. No acne but skin a little oilier. No roid rage, but sometimes higher frustration/irritation over annoyances - but I would not really call this a side effect as it had no negative issues for me. When I was was on 1 a month injection it see-sawed my libido - start of the month I was very horny (more Os but quicker recovery), near the end of the month - poor libido + erections issues (by the end of the month the injected T had worn off and my own natural T was suppressed due to the higher levels at start of month signalling my body to lower production + also probably higher estrogen levels relating to the spike in T earlier in the month. My testicles would feel cold at the end of the month and pois was definitely worse. Stable levels are totally the way to go.
Before I went on TRT, I had suffered from dandruff (linked to pois somewhat) and this disappeared (great!) Also my levels of anxiousness & self consciousness (linked to pois) reduced, but really only when I went up to the higher levels.

[fornicationDENIED2]

Personal ancedotes: TRT has cured my POIS.
......

FD, that's a pretty high dosage of T. Is your doctor prescribing you this amount or are you undertaking this on your own?
the cypionate ester if I remember right has a short half life, so you will need more frequent injections,but that is still a high dose, from a 'conventional' medical perspective. I am on Testosterone Ethanate (longer half life) and am currently at 100mg a week, which is higher than what my doctor wanted, but I feel better for it and have never scored high on T blood tests (with just T injections).

When I was originally put on T shots it was a once a month injection, and that screwed me up - way too much fluctuation, and my pois got worse. I split my doses up and increased the amount I was taking and I was a lot better for it. I did this then told my doctor and he reluctantly went along with it. The official doctors drug manual for Sustan250 for instance still recommends once a month injection. I found I was struggling by day 18 and when I had blood tests on say around day 10-12, my levels were at 1/4 of the normal range.  I have experimented with T by taking high doses at your levels and had mixed results. In the cooler months of the year I felt better for it and put on weight and my pois was less. In the warmer months of the year it seemed to make no difference. I had increased stress levels & more hair loss though. Its weird and very very frustrating. The only time I put on weight is in the cooler months. I still lose weight in the summer even during the times I was on 100mg+/week.

I took an OTC anti aromatase + also herbs. I did not experience any gyno, but some people are less susceptible. I have low body fat levels.  When I trialled 200mg/week, I took Clomid when I dropped my T intake back to lower levels, and I cant say I noticed anything, but then I did not crash so it could have been doing its job well. I did not get any T blood tests to verify my levels at this time.

I had good results with the herb TongkatAli which boosts LH ( and maybe also FSH levels) and testosterone a number of years ago. I have since tried it a few more times but have been disappointed. This is a potent herb and grown only in limited part of the word and there is a lot of bogus/weak product out there now being marketed. I feel this would be a good herb for some pois'ers to try. Unfortunately I cannot recommended a good source. It very expensive now too. I have asked a couple of my doctors about trying Clomid or Pregnyl to increase my natural T levels but they are not interested.

I also experimented by taking Nandrolone as well as Testosterone (lower dose - 60mg/week) and found taking the two together to be more potent at the equivalent dose of just testosterone. (blood test for T levels showed me at the top end of normal for the first time in my life) My pois was much better too, however like the comment I made earlier about T being more beneficial for me during the cooler months, it is the same story when I take T & N, alas.  My pois has always been less in the cooler months even before I took any supplements. I can't remember anyone else here saying there was a seasonal component to pois. Around the same time I got pois I got chemical sensitivities + food intolerances. I tested at very high on IgE levels (related to allergies) and strong reaction to many grasses (even though I don't get hayfever anymore - that stopped when I got pois). I wonder if the grasses which are high except in the cooler months are impacting badly on my immunity/endocrine system...even though I don't have hayfever.

I cannot comment on pois in relation to my IGF-1 levels, as I have never had a good IGF-1 reading. I have below normal IGF-1. Same with DHEA.  There certainly could be a connection though.

Is your doctor prescribing you this amount or are you undertaking this on your own?  More like 50/50, the problem is, there is a depopulation and anti male agenda, and if I lower my dose and it does not work anymore I will get a hard time getting to the place I used to be. Besides, I am not experiencing side effects. Test cypionate has a 8 day half life I believe.

I think I read somewhere that low DHEA is an indicator of high cortisol and high cortisol would explain the low IGF- 1. I also read that increasing DHEA would suppress cortisol, which is why I experimented with DHEA supplements. You can also try HGH(human grwoth hormone) which will solve the IGF1 issue and will add some extra benefits like increased dose dependent collagen synthesis including other anti aging benefits. But there is a witch hunt againt HGH sadly which makes it hard to get (plus it is expensive as F...) Circulating IGF-1 is generated by the liver under the control of growth hormone (GH). The binding of GH with its hepatic receptor stimulates expression and release of IGF-1 peptide in the circulation, which has high affinity for IGFBPs, and represents the endocrine form of IGF-1
but that thing is very useful to the point that it would have regenerated my ulcerated intestines in weeks. IGF-1 is EXTREMELY IMPORTANT ,IGF-1 supports cellular division and growth to the muscles and organs among other things, you have to fix that quick.


 IGF-1– can induce reduction in oxidative stress, cell apoptosis, proinflammatory signaling, and endothelial dysfunction. Aging is associated with increased vascular oxidative stress and vascular disease, suggesting that IGF-1 may exert salutary effects on vascular aging processes.

Hypertension is a major risk factor for atherosclerosis, and aging influences the prevalence of hypertension, whereas aging by itself appears insufficient to induce hypertension (168,169). As described above, IGF-1 increases endothelial NO production; hence, a major part of IGF-1 effects on vascular tone regulation can be attributed to eNOS–NO dependent mechanisms. In addition, insulin/IGF-1 reduces [Ca2+]i and Ca2+-MLC sensitivity in VSMC (170,171), thereby inducing vascular relaxation.

http://biomedgerontology.oxfordjournals.org/content/67A/6/626.full

If you are interested I will post more studies later .

[fornicationDENIED2]

To all TRTers .. have you experienced any minor/major side effects ?

Well, the problem whit testosterone is that there is alot of misinformation particularly the fear mongering from the media.

I know what you truly are concerned about hahahaha, and the answer is no, TRT will not decrease the size of your ... how do I put this without getting banned... gentleman's sausage. I have personally experienced an increase in 0.5 inches in length and more girth but not enough to live my POIS free life as a pornstar sadly.