[meteo74]

Hi everyone,

I found this thread after realizing I had POIS. It was getting worse for me over time and now that I have a girlfriend my symptoms were really showing up.

I would feel tired/achy/grumpy for a day or two after sleeping with her, and the more we slept together the worse it got. It felt like a hangover from a really bad night of drinking.

I tried taking more vitamins, changing my sleep/exercise routines/, not watching porn anymore, etc., which all helped but never solved the problem.

Finally what worked for me was getting off of gluten. My POIS that I've had for many years vanished!

I just wanted to log in and share my experience in case it helps anybody searching for an answer. I know I got to the point where I was willing to try anything that might have helped, so here's another thing to try.

Good luck to everyone.

Sincerely,
Seth

hi sethlessness
what does gluten mean,i look for it in google translation but can't understand ,would you say some,and how many years were you in pois..
thank.

[MrVat7]

What Testosterone dosage do you take TRTers ?

[MrVat7]

I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?

[LAPOISSE2]

Hello to all of you,

I've been investigated the gluten lead recently and I think there is something :

-First of all, there is different testimony of people flaming that there are pretty much POIS free since they eliminate the gluten from their diet

http://poiscenter.com/forums/index.php?topic=1240.0

http://poiscenter.com/forums/index.php?topic=387.msg10629#msg10629


Seth recently :

http://www.thenakedscientists.com/forum/index.php?topic=6576.19475

-Some people have been diagnosed with gluten allergy(kurtosis, urano, etc)

-If you read about gluten intolerance/sensitivity, you find out that there is tons of potential symptoms ; it's due to the fact that (i) gluten triggers autoimmune reaction with the typical symptoms of it and that it can cause malabsorption and deficiency(of amino acid/vitamins/minerals) that lead to various symptoms and can explain the fatigue and the cognitive impairments.

-One the promising "cure" some year ago was multivitamin program ; helped a lot ; It's not surprising if we have deficiency and potentially lead to digestion problem.

-Some people I've talked with doesn't get weight easily and I'have read in POIS forum that they have greasy/sticky faeces and digestion problem : it's typical if gluten intolerance is involved ; we don't digest fat.

I believe that Orgasm/sexual activity just trigger/worsen an underlining problem ; It's maybe a mistake to focus on O.

Nevertheless, there is a link between potentially digestion and Orgasm...and this could be the Vagus nerve(object of the ongoing POIS research).

Personally I will verify that lead and going to a strict non gluten diet for at least 2 month

good luck fellow poiser's

[LAPOISSE2]

That is interesting too ; the part I like the most is :

"interesting fact that her problems were not constant, indicating that basically her brain was intact but something seemed to be detrimentally influencing her from time to time, causing her to have these significant issues with respect to how her brain functioned. In considering what factors change day to day in terms of someone's exposure, certainly diet is at the top of the list"

http://www.huffingtonpost.com/dr-david-perlmutter-md/gluten-impacts-the-brain_b_785901.html

[Kima]

LAPOISSE2

I fully agree with you!

[Kima]

vagus nerve

Treatment. Analgesics for pain relief used in combination with antihistamines, anesthetics (0.5% novocaine solution intravenously), B vitamins (cyanocobalamin - 1000 mcg and thiamine chloride - 1 ml of 0.5% solution intramuscularly every other day). Of physiotherapy appointment effectively diadynamic currents pain radiating portion. 

Treatment. B vitamins, stimulants, neostigmine (0.015 g), atropine (1 ml of 0.1% solution subcutaneously). When the etiology of diphtheria - large doses of diphtheria serum

Maybe that's why vitamins helps people?

[Kima]

Pois syndrome are very similar to nerve disease . Likely sperm touches a nerve and so we get these symptoms

[MrVat7]

Sounds possible kima.

[fornicationDENIED2]

I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?

I would not take Finasteride if I was you because DHT is not exactly as dangerous and destructive as estrogen can be . First you must get a blood test (a couple of days after injection, but I would wait around 3 weeks of treatment before testing, also do not test yourself at the testosterone peak which is around the 2 or 3 day but on the 4th or 5 day)  to see if DHT is outside the range , and or experience detrimental DHT side effects, then take it. Finasteride side effects include impotence, loss of sex drive(obviously caused by low DHT, can't prove if you are POIS free if that happens hahaha), it could (not guaranteed)  also cause anxiety and depression.
 Anastrozole binds reversibly to the aromatase enzyme through competitive inhibition, meaning once daily makes sense but if you need to lower dosage try a formula like 0.5mg daily, since this drug has short lasting effects and keep in mind your estrogen cant be zero or extremely low, since it can cause fatigue and other side effects.

[demografx]

I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?

[Former Moderator visiting periodically]

I recommend to anyone contemplating TRT for your POIS: discuss infertility risks carefully with your doctor!!!!

[MrVat7]

I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?

[Former Moderator visiting periodically]

I recommend to anyone contemplating TRT for your POIS: discuss infertility risks carefully with your doctor!!!!

Ive discussed this with my doctor. He says that injecting sustanone 250 till 6 weeks will bring sperm count to zero ( ie azoospermia ) and then if I stop taking injections sperm count would recover within 9 months.

I am still 18 so do not have to produce kids. So no worry.

[demografx]

[Former Moderator visiting periodically]

Excellent! []

[LAPOISSE2]

Hi everyone,

I found this thread after realizing I had POIS. It was getting worse for me over time and now that I have a girlfriend my symptoms were really showing up.

I would feel tired/achy/grumpy for a day or two after sleeping with her, and the more we slept together the worse it got. It felt like a hangover from a really bad night of drinking.

I tried taking more vitamins, changing my sleep/exercise routines/, not watching porn anymore, etc., which all helped but never solved the problem.

Finally what worked for me was getting off of gluten. My POIS that I've had for many years vanished!

I just wanted to log in and share my experience in case it helps anybody searching for an answer. I know I got to the point where I was willing to try anything that might have helped, so here's another thing to try.

Good luck to everyone.

Sincerely,
Seth

Hey All,

Nobody care about that ? We're all desperately trying to find a cure, someone show up saying that eliminating something from its regimen(not a big deal) kinda cured him and nobody make attention to it..
I know we've had many "magic cure" but believe me there is many other case and malabosption induce disease is not like breathing with right nostril or swallowing some magic  chinese herb...All the guys that talked about gluten problem in here never came back ; As we said in France, No news : good news

It just makes a lot of sense, digestion is the entrance door of our complete health...what you put in your mouth make you healthy or not.We are all looking for a root cause of our problem, this could be one.If your deficient is minerals or vitamins, all the system is screwed and orgasm could just be the spark. Gluten can be the root cause of many disease, POIS could be of them

Please guys, react to this, don't be blind...there is no certitude at all, but it definitely worth to investigate.

And if you have time, read about what is gluten intolerance

This is one of many article about it :

http://www.mindbodygreen.com/0-7482/10-signs-youre-gluten-intolerant.html`

By the way, do we any chinese or japanese here ? Saw 1 chinese in 3 years of looking at the forums...Why ? Maybe because they have no gluten at all in their diet

[LAPOISSE2]

This one also is ver very interesting :

http://chriskresser.com/50-shades-of-gluten-intolerance

[gpg]

hi guys,
Although I do not have POIS, I think that I may be able to throw some light on where to focus or investigate to track down the source of the problem.
Actually, I have the symptoms of POIS all the time, and always have had, which is why I found this forum.
But my symptoms are caused by life-long bilateral tumours of my adrenal glands, also known as pheochromocytoma (PCC), usually benign, but which release large quantities of adrenaline (epinephrine) into the bloodstream, either continuously or intermittently.
This is all very new to me too, and not fully-confirmed because I am still working through the full suite of tests and imaging studies for PCC. Initial imaging studies show a tumour within each adrenal gland and I have all the classic symptoms of PCC.
Its a pretty rare condition and one autopsy study found that 75% of patients die without being diagnosed - usually having been labelled "crazy".
It seems quite plausible to me that sexual arousal, activity and orgasm is triggering the release of a large adrenaline hit and causing POIS in susceptible men.
Do any of you guys have secreting adrenal tumours? Probably not, but I would suggest that the adrenal glands are at the pathophysiological centre of POIS whatever the actual pathological mechanism.
I read that some of you guys have had lots of standard blood tests, including hormonal ones too, like testosterone. But, unless you specifically have an endocrinologist, who actually suspects PCC, it is highly unlikely that you have had the blood and urine tests which will link POIS to the adrenal glands. Very often, even in PCC patients, the blood testing does not pick it up for various reasons, so the blood tests are backed up with 24 hour adrenaline in urine testing. Anyone on here done the latter?
Excessive adrenaline release really messes around with your blood pressure and heart rate for quite a long time afterwards so these physical correlates could offer some objective evidence for POIS. It messes with your brain too, as you know from experience, but that is more subjective.
Has anyone with POIS been regularly using a personal blood pressure and heart rate monitor? I would highly advise every POIS patient to buy an automatic one (battery-operated) not a manual one. They are available very cheaply everywhere. I use a wrist-mounted one rather than upper arm which are a lot smaller and less cumbersome to use. Most have a memory for around 60 to 100 readings. Just remember that when you take a reading with a wrist monitor your wrist must be on the same level as your heart. All the information that you need on this post will be found in the monitor instruction manual.
I would start by taking blood pressure readings when you are feeling well ie. after a week or two without sexual activity. Take two readings at rest - one after you have been lying horizontal for 5 minutes or more and then stand up and immediately take another reading and repeat this through the day. If you are well, then both your readings should be in normal range as advised on the monitor. When you stand up, you should get a similar blood pressure or maybe a lower one to the horizontal, but definitely not a higher one (ie. orthostatic hypertension).
Then, after orgasm, start taking regular readings when horizontal and immediately after standing up. Remember to keep your wrist at heart level when reading standing up.
Does your blood pressure remain in normal range after orgasm? Only when horizontal? Only when vertical? Or both? If your blood pressure increases after standing up then that is a red flag for excess adrenaline release.
Keep an eye on your heart rate during the readings too - is the monitor alerting any heart rate increases above normal?
Make a note of any headaches against the readings - rate the severity of the headaches. You might even have a continuous low-level headache during the days after orgasm?
Write down the dates and times of the blood pressure/heart readings from the monitor memory on to a calendar - is there a pattern over the days after orgasm? Anything noteworthy?
Ultimately, is there a similar pattern found in all POIS patients?
Well, I really hope you guys find this post useful. I am as interested in POIS as you are.
I will stay on the forum and reply to any responses - or any private emails.
It would be really fascinating to generate some medical data on POIS with this approach.
regards
gpg

[LAPOISSE2]

hi guys,
Although I do not have POIS, I think that I may be able to throw some light on where to focus or investigate to track down the source of the problem.
Actually, I have the symptoms of POIS all the time, and always have had, which is why I found this forum.
But my symptoms are caused by life-long bilateral tumours of my adrenal glands, also known as pheochromocytoma (PCC), usually benign, but which release large quantities of adrenaline (epinephrine) into the bloodstream, either continuously or intermittently.
This is all very new to me too, and not fully-confirmed because I am still working through the full suite of tests and imaging studies for PCC. Initial imaging studies show a tumour within each adrenal gland and I have all the classic symptoms of PCC.
Its a pretty rare condition and one autopsy study found that 75% of patients die without being diagnosed - usually having been labelled "crazy".
It seems quite plausible to me that sexual arousal, activity and orgasm is triggering the release of a large adrenaline hit and causing POIS in susceptible men.
Do any of you guys have secreting adrenal tumours? Probably not, but I would suggest that the adrenal glands are at the pathophysiological centre of POIS whatever the actual pathological mechanism.
I read that some of you guys have had lots of standard blood tests, including hormonal ones too, like testosterone. But, unless you specifically have an endocrinologist, who actually suspects PCC, it is highly unlikely that you have had the blood and urine tests which will link POIS to the adrenal glands. Very often, even in PCC patients, the blood testing does not pick it up for various reasons, so the blood tests are backed up with 24 hour adrenaline in urine testing. Anyone on here done the latter?
Excessive adrenaline release really messes around with your blood pressure and heart rate for quite a long time afterwards so these physical correlates could offer some objective evidence for POIS. It messes with your brain too, as you know from experience, but that is more subjective.
Has anyone with POIS been regularly using a personal blood pressure and heart rate monitor? I would highly advise every POIS patient to buy an automatic one (battery-operated) not a manual one. They are available very cheaply everywhere. I use a wrist-mounted one rather than upper arm which are a lot smaller and less cumbersome to use. Most have a memory for around 60 to 100 readings. Just remember that when you take a reading with a wrist monitor your wrist must be on the same level as your heart. All the information that you need on this post will be found in the monitor instruction manual.
I would start by taking blood pressure readings when you are feeling well ie. after a week or two without sexual activity. Take two readings at rest - one after you have been lying horizontal for 5 minutes or more and then stand up and immediately take another reading and repeat this through the day. If you are well, then both your readings should be in normal range as advised on the monitor. When you stand up, you should get a similar blood pressure or maybe a lower one to the horizontal, but definitely not a higher one (ie. orthostatic hypertension).
Then, after orgasm, start taking regular readings when horizontal and immediately after standing up. Remember to keep your wrist at heart level when reading standing up.
Does your blood pressure remain in normal range after orgasm? Only when horizontal? Only when vertical? Or both? If your blood pressure increases after standing up then that is a red flag for excess adrenaline release.
Keep an eye on your heart rate during the readings too - is the monitor alerting any heart rate increases above normal?
Make a note of any headaches against the readings - rate the severity of the headaches. You might even have a continuous low-level headache during the days after orgasm?
Write down the dates and times of the blood pressure/heart readings from the monitor memory on to a calendar - is there a pattern over the days after orgasm? Anything noteworthy?
Ultimately, is there a similar pattern found in all POIS patients?
Well, I really hope you guys find this post useful. I am as interested in POIS as you are.
I will stay on the forum and reply to any responses - or any private emails.
It would be really fascinating to generate some medical data on POIS with this approach.
regards
gpg

Hey, My doc thought I had these to because I was doing a bit of tachicardia ; I've tested my BP for a month and tested the blood and urine catecholamines and all was pretty normal..

[acronym]

gpg - thanks for that interesting post.
Q - Did having an orgasm make any difference for you, having PCC (I would have thought it would have)?
Q - Were you underweight and had great difficulty putting on weight?
Q - Did you have headaches most days of the week?
Q - Were you up and down between 'wired & anxious' and 'exhausted & brain foggy'?

I have never had high BP. In fact I was on the low side for many years and normal blood glucose levels, and lack of sweating as opposed to excessive sweating, but ticked the other symptoms. cheers

[MrVat7]

Do Poisers feel symptoms in summer ?

[Colmik]

After the vast amount of information given in this thread, I don't suppose this post will be of any value, but I'll throw it into the ring in case it sparks an idea ion somebody's mind.

I had a PSA test a few months ago.  PSA = Prostate Specific Antigen - an indicator for prostate cancer.
My count was 3.8, which was said to be safe for my age (less than 4.0), but I was still a bit concerned, as my previous count, a couple of years ago, was 2.0.   I was told that the reading is most reliable if it is not taken within three days of an orgasm.

So it seems that it takes several days for PSA levels to settle down.  Could that be connected with the subject of this thread?

Oh, well, I said it probably wasn't important!