Post Orgasmic Illness Syndrome (POIS)

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Offline ragnarlind

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19600 on: 11/07/2014 18:15:13 »
Hello ... I have not posted here for ages and as far as I can tell there is nothing very new going on for our syndrome ...
There are some perhaps relevant thoughts about how "stress" debilitates many body functions on a cellular level ... see Sapolsky's great documentary about "self esteem stress" impacting weight gain (around the belly), artery sclerosis , depression, dopamin function etc.
https://www.youtube.com/watch?v=eYG0ZuTv5rs

For me it is clearly a dopamine collapse happening around 6 hours after an O and then symptoms lasts for about a week. Headache (frontal lobe), severe grumpiness (poor my lovely wife).  I was first introduced to this hang-over syndrome http://www.reuniting.info by Marnia Robinson who still has the best explanation for how nature has genetically programed us for gene diversity, by finding fault with our mates after orgasm and looking for a NEW mate (see the Coolidge Effect -- http://www.reuniting.info/science/coolidge_effect ). 
My feeling is that many more people experience some variety of this than us POISers but that they don't connect the dots. If the symptoms are delayed it is not easy to say that there is a connection unless you have been alerted to the possibility of it !  Others, like me, have enough head aches so that it does not stand out (unless you look for it). The grumpiness, the brain fog, the cold symptoms, back aches etc. can be the same lack of connection so it is disappearing in our general up and down character...
So dopamine (the desire hormone) ... it falls sharply after orgasm but for some it disappears from the scale and keeps going down in waves ... total dopamine loss which affects the brain in many negative ways -- depression, memory loss and loss of other functions. Marnia's alarm started me looking and got me to the POIS page and for me the connection is obvious -- not so for everybody. There are many who want to find an answer that can be handled by antibiotics or some other pill. Perhaps there is some such solution for some I have not found one. I have never found Dr. Waldingers allergy autoimmune theory convincing, that we should be allergic to our sperm or semen ...
There was hope in Marnia's recommendation to skip frequent orgasms and practice Karrezza but for me that lead to another very disappointing discovery: that even getting "horny" triggered the hang-over respons but in a milder form. Still headaches but perhaps less intense. So how to deal with massive dopamine loss ? One that works but is dangerous is aspirin+codeine ... the morphine takes care of the dopamine loss but if you take it for more than 3 days you are hooked ! So you have to be aware and stop looking for relief at the 3d day onward. Oh well ... this is where I am now :-(

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Offline desperate man

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19601 on: 11/07/2014 21:17:43 »
Yes, the dopamine theory is still the most convincing for me. I have came across a study few days ago which mentions the reward circuit and food connection. It was saying something about junk food, high sugar downregulating dopamine production.

Basically if you have insufficient dopamine/or faulty receptor activity then you will crave junk food. Catch22. Dopamine plays a huge role in hunger and weight loss, weight gain.

I occasionally get POIS-like symptoms from very sugary foods. Other times it lifts my mood and gives me energy. It's very difficult to pin-point things but it could to be tied together to a combination of:

- adrenal hormone (cortisol) regulation throughout the day and your time of ejaculation in 24 hours period
- hunger and the foods you consume (are you starving yourself? it will screw up your adrenals)
- actual dopamine activity

I know that my symptoms are a result of losing a parent early in life (PTSD), previous SSRI use and the endless cycle from POIS causing fear and depression.

After further reading about the subject I truly feel that Cognitive Behavior Therapy could be an option in rewiring the brain and letting past traumas go in cases like mine, in which supplements do nothing but harm.
« Last Edit: 11/07/2014 21:39:50 by desperate man »

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Offline desperate man

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19602 on: 12/07/2014 22:33:03 »
Is there a way to boost dopamine or dopamine receptor activity without triggering panic attacks? Feeling intelligent is such a good quality to have, at least there would be a compensation for the rest of the POIS symptoms.
I'm trying skullcap caps in order to boost GABA receptors to counteract delusional thinking and paranoia. I don't know if it will help with the low dopamine and 0 motivation though, but it will definetly lower norepinephrine, which if high will make you stupid...

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19603 on: 13/07/2014 12:15:48 »
DM, it is possible to eliminate all sources of lust, but it takes commitment. I am a devout Catholic and adhere to it's instruction that avoiding all situations that lead to temptation will block temptation. I am living proof that a person can live (most of the time) without lust entering his mind, something unthinkable years ago. I don't watch many tv shows, very few movies (make sure they have no passion in them, and if they do I turn off the volume and avert my eyes) Sound crazy? It aint, it works! Online I am able to resist a search in the wrong direction that would spell certain disaster. I believe that worshiping God (obedience to His rules) gives me the ability to walk without falling. The only POIS that now afflicts me is very occasionally when I have an NE, otherwise I am a chase single person. I just wanted to let you know that there is hope from the maelstrom that of POIS.

As far as increasing dopamine, you can try consuming fava beans. I buy them dry and boil them, and include some with other beans for my evening protein most nights. Protein in general is very valuable to anyone with mental instability. I recommend a protein shake in the morning with breakfast, they contain lots of the amino acids used to build neurochemicals.

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Offline Nightingale

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19604 on: 13/07/2014 19:55:16 »
Guys, on dopamine:

It's not the answer. I've tried everything you can do to modulate/upregulate/downregulate dopamine. Stimulants. Parkinsons drugs. Antipsychotics. And on and on. I've been through serious medical care for a period of 5 years because of mental illness, and I've had the opportunity to work with the best physicians out there. I've been seen at the National Institutes of Health here in the USA, and I had the ex-director of the entire inpatient center of the NIH (a psychiatrist) literally pull everything out of his hat to see what it would do dopaminergically.

The dopamine theories of mental illness and mental health are old news. They are losing relevance in light of research that points to the brain working on neural circuits and specific pathways that primarily create good health or poor health.

I personally found out just how important pathways are when deciding to undergo electroconvulsive therapy. It changed my life and SAVED ME from major depression. The repeated shocks and seizures formed new pathways that to this day are the main reasons I am thinking more about life and less about death!

That's why I'm so excited about our research, it focuses on a nervous system dysfunction. Nerve tone is essential for your brain's communication with our body, and if our nerves are not toned, or "out of tune", you can get over or under stimulated. And with as complicated a nerve as the vagus nerve is (the one being studied), this means a LOT of things would go wrong, and that's what I believe we see with POIS.

How can you help yourself with this approach/theory? Stimulate your body in a healthy way! It seems to me that ejaculation seriously disrupts the state of the nervous system. I have found for myself that if I engage in 1-2 hours of vigorous cardiovascular exercise (like biking or running), then I feel MUCH more peaceful. This would be explained by exercise's modulation of the autonomic nervous system. What else works? Meditation. Mindfulness meditation allows the brain and body to enter into a protective state, where you can handle anxieties more easily and identify sources of pain, physical and psychological. The more active I am, the better I do, and the more I sit in quiet contemplation on a regular basis, the more I can handle.

I truly believe this has to do with engaging my body's natural mechanisms to regulate nerve tone.

I think that vagal nerve stimulation has a lot of promise for us, and I look forward to some great work done in our study!

IF YOU FIND THAT THOUGHTS OF DEATH AND KILLING YOURSELF ENTER YOUR MIND, PLEASE MAKE SURE YOU UNDERSTAND YOU ARE CONSIDERED MAJORLY DEPRESSED AND WOULD BE A CANDIDATE FOR ELECTROCONVULSIVE THERAPY. It IS safe. It IS powerful. Take my results as evidence. I was very scared going into it, but it HAS BEEN THE CHOICE THAT HAS SAVED MY LIFE. DON'T HESITATE TO ASK YOUR DOCTOR.

But on a last note, I do find that anti-inflammatories help me deal with POIS. If I take NSAIDs before I ejaculate, I have reduced symptoms. BUT. NSAIDs are dangerous in the long term, and I have found a GREAT replacement in the form of curcumin, the active ingredient in tumeric root. Find a product that CONCENTRATES it, like Terry Naturally's Curamed or Curamin. I have been feeling less aches and pains, and my recovery times are faster.

Best,
Nightingale
« Last Edit: 13/07/2014 19:58:30 by Nightingale »

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19605 on: 13/07/2014 20:21:06 »
Nightingale,
I'm curious, have you tried turmeric instead? Does curcumin have a different effect for you? It seems that it wouldn't as curcumin is a component of turmeric.

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Offline Nightingale

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19606 on: 14/07/2014 01:32:45 »
If you eat/take tumeric, you are eating/taking curcumin. There is no difference. Now, if you are SUPPLEMENTING with highly concentrated curcumin, thats the difference.

And yes, I have tried tumeric. It's in so many Indian dishes. You would have to eat so much that you would be sick, though, to achieve what you can with supplementation. A diet heavy on tumeric is not going to be realistic as a treatment.

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Offline Kima

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19607 on: 14/07/2014 05:48:37 »
Guys, on dopamine:

It's not the answer. I've tried everything you can do to modulate/upregulate/downregulate dopamine. Stimulants. Parkinsons drugs. Antipsychotics. And on and on. I've been through serious medical care for a period of 5 years because of mental illness, and I've had the opportunity to work with the best physicians out there. I've been seen at the National Institutes of Health here in the USA, and I had the ex-director of the entire inpatient center of the NIH (a psychiatrist) literally pull everything out of his hat to see what it would do dopaminergically.

The dopamine theories of mental illness and mental health are old news. They are losing relevance in light of research that points to the brain working on neural circuits and specific pathways that primarily create good health or poor health.

I personally found out just how important pathways are when deciding to undergo electroconvulsive therapy. It changed my life and SAVED ME from major depression. The repeated shocks and seizures formed new pathways that to this day are the main reasons I am thinking more about life and less about death!

That's why I'm so excited about our research, it focuses on a nervous system dysfunction. Nerve tone is essential for your brain's communication with our body, and if our nerves are not toned, or "out of tune", you can get over or under stimulated. And with as complicated a nerve as the vagus nerve is (the one being studied), this means a LOT of things would go wrong, and that's what I believe we see with POIS.

How can you help yourself with this approach/theory? Stimulate your body in a healthy way! It seems to me that ejaculation seriously disrupts the state of the nervous system. I have found for myself that if I engage in 1-2 hours of vigorous cardiovascular exercise (like biking or running), then I feel MUCH more peaceful. This would be explained by exercise's modulation of the autonomic nervous system. What else works? Meditation. Mindfulness meditation allows the brain and body to enter into a protective state, where you can handle anxieties more easily and identify sources of pain, physical and psychological. The more active I am, the better I do, and the more I sit in quiet contemplation on a regular basis, the more I can handle.

I truly believe this has to do with engaging my body's natural mechanisms to regulate nerve tone.

I think that vagal nerve stimulation has a lot of promise for us, and I look forward to some great work done in our study!

IF YOU FIND THAT THOUGHTS OF DEATH AND KILLING YOURSELF ENTER YOUR MIND, PLEASE MAKE SURE YOU UNDERSTAND YOU ARE CONSIDERED MAJORLY DEPRESSED AND WOULD BE A CANDIDATE FOR ELECTROCONVULSIVE THERAPY. It IS safe. It IS powerful. Take my results as evidence. I was very scared going into it, but it HAS BEEN THE CHOICE THAT HAS SAVED MY LIFE. DON'T HESITATE TO ASK YOUR DOCTOR.

But on a last note, I do find that anti-inflammatories help me deal with POIS. If I take NSAIDs before I ejaculate, I have reduced symptoms. BUT. NSAIDs are dangerous in the long term, and I have found a GREAT replacement in the form of curcumin, the active ingredient in tumeric root. Find a product that CONCENTRATES it, like Terry Naturally's Curamed or Curamin. I have been feeling less aches and pains, and my recovery times are faster.

Best,
Nightingale


I agree with you.

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Offline Kima

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19608 on: 14/07/2014 20:29:07 »
Dear Sir, I appreciate your concerns. What I proposed in the application was an hypothesis to be tested. This project is NOT anyone's doctoral dissertation; it is my own research project with collaborators, all of whom are doctors. While for formality, it is necessary to present a research protocol for approval by my University ethics committee, in reality, it will be necessary to do "pilot" research along those lines, starting with one or two POIS sufferers, requesting their feedback as to possible effectiveness, and inviting, and responding to, their suggestions. I do not intend to blindly proceed with the protocol on 12 POIS sufferers without obtaining continuous feedback and suggestions from each person. But please remember: this is research, NOT therapy. I appreciate your and the other POIS sufferers' sense of urgency and desperation. There are no guarantees in research; if there were, it would be therapy, not research. An hypothesis is an assertion that may be right or it may be wrong. Hopefully, by testing it in a flexible way (i.e., adjusting to results as they develop and modifying procedures that seem appropriate and useful), our knowledge of the cause(s) of POIS will improve and possibly lead eventually to therapy. Furthermore, I must await approval by our University ethics committee (i.e., IRB) before commencing the research. I expect that to occur at the beginning of next month. Sincerely,

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Offline MrVat7

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19609 on: 16/07/2014 14:27:24 »
Guys, on dopamine:

It's not the answer. I've tried everything you can do to modulate/upregulate/downregulate dopamine. Stimulants. Parkinsons drugs. Antipsychotics. And on and on. I've been through serious medical care for a period of 5 years because of mental illness, and I've had the opportunity to work with the best physicians out there. I've been seen at the National Institutes of Health here in the USA, and I had the ex-director of the entire inpatient center of the NIH (a psychiatrist) literally pull everything out of his hat to see what it would do dopaminergically.


Hello nightingle
Have u tried taking dopamine stimulants in higher dosage ? i have tried taking modafinil . which has weak Dopamine reuptake inhibition at very high dosage( 2.5 grams ) so it had and intense dopamine reuptake inhibition and i felt absolutely no POIS.

It may be that we POISers have very high and continues dopamine reuptake .. so normal doses may not work for us.. but DRI at high doses can block almost all dopamine reuptake sites giving us freedom from symptoms.

MrVat7

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Offline desperate man

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19610 on: 18/07/2014 16:53:45 »
Guys I think I'm onto something. If you would be so kind and share the actual chemical excretion during orgasm from most reliable source please do. I'd be grateful.

I'm connecting my case to a rare, recessive inherited condition involved in metabolizing sugar compounds. Will share more, but need to do my research first.
This is very promising and I even found studies that linking compounds to Ejaculation Retrograde, which has been a hot topic in the past, but nobody could connect the dots.

Edit: http://www.encognitive.com/node/10925 Is this a good source?
Thanks!
 
« Last Edit: 18/07/2014 17:40:03 by desperate man »

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Offline nathan123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19611 on: 24/07/2014 10:23:06 »
Hi, first I want to confess to this forum. As around several months back, I intimated to this forum that, I was cured from POIS. Factually, I got only few hint during that time for curing of POIS and due to the intention others to try my method, I intentionally posted that I am cured. Factually, I was not cured during that time. I sincerely apologies for my wrong information provided to this forum and for this wrong information provided to this forum, I get punishment from God and the punishment which is as below. 
In our country, people would believe in Astrology. One of my friend has gone to the Astrologer and he by his technique of astrology, told to my friend that I am gay. (I think the astrologer by this technique, understand that there is some problem sexually and took a wrong conclusion that I am a gay.).  My friend who has very faith in that astrologer believed that I am a gay and he started to spread this message to all people without any medical examination and people started to check me thinking that I am a gay and news spread to anyone. Even though I explained this POIS, its symptoms to few people, it seems they not believed this and they are thinking downfall after organism for several days as a Gay which is very unfortunate to me. Finally, I showed my genital to my friend to prove I am not that. It seems, still he has not trusted me even though I showed him the genital which is very unfortunate and presently I am in a position to leave my city due to spreading of bad news on me.   
Good news is I found few technique to found relief from POIS and found success in April and May. However, due to the above problem, I am not in a position to fully implement that technique and I hoping I would found a cure from this and my fight for POIS would not stop and only after founding of complete cure from the problem, I would post to this forum. 

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Offline nathan123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19612 on: 24/07/2014 19:13:18 »
Hello friends,
I decided to suicide myself as I am not able to tolerate the life. This is my death note. If I provide my death note to people in my city, no body would believe what I am saying. Thatís why I am providing my death note to this forum, so that atleast you guys would trust what I a a m saying and there would be a peace to my soul. Reason for sucide is as below
As posted in my previous post, people in my city are though that I am gay and they are spreading the message to all the people in the city. Further, my parents, my friends, my boss, my colleagues are under the assumption that I am Gay. With add to this, from the past several years, I am helping others too much and I am taking extra care of so many people and I am soft corner to all the people. Why I am doing this, for each help / each extra care / each soft care taking to others, I am praying with my god is that god please cure my POIS and see how I am helping to others. But people around me incluing my parents, my boss, my friends, thought that I am a gay and due to this, I am helping so much to others. But factually, as explained above, I am helping other because, I want to show god that how I am helping everyone and also with intention of my future business plant.  Due to this my too much helping nature along with POIS symptoms, people misunderstand me and they thought that I am a gay. Initially, I have around 500 people who had trusted me. But as of now, I not had even a single person who will trust me.  I not done even  a single mistake / harm to others and not seen any of them sexually except for one girl I loved her and later as she rejected had a quarrel with her and told many lies in this area and also I not taken care my parents and neglected them. Apart from this, I have not done a single mistake / error / bad behaviour in past 6 years of life. 
However, I confess that in my childhood, i.e. around 10 years back, I have done few mistakes in my life and I realized those mistakes and I never did such a mistake. As explained in my previous post, my astrologer has identified my childhood bad behaviour and he believed that I carrying that behaviour now also and spreaded bad message to my family. He not understand how I changed from 2005 and doing only good things in life and not at all scold any one even if they do any wrong thing, how helpful to others in teaching, giving jobs, giving money, solving problems without any much expectation except praying god for my care and also my future business help.
But, to all the people to whom I had helped, not understanding me.  Thatís why I came to a conclusion that people like me i.e. very sincere, honest, good, too much caring person is not possible to live in this commercial life, as people had different thing in thier mind and even thgough I had done good work with the intention, would not understand. Thatsís why I am realized that I am become too much honest and it is not possible to live in this world and also not possible to facIe POIS.  After my POIS cure, I had a dream of helping orphans. But now, I am leaving my life without achieving my objective i.e. to help orphans and unfortunately, now I am dying as a orphan even though I had so much of friends, parents etc and it is not of any oneís mistake. I also acknowledge my friends reaction to my behaviour as they are normaly commercial people and not abnormal like me where I helped too much to all that one no body would do in this era. So, I felt, my fate is not good and due to this, I am leaving my life at this young age of 26 and my death day is tomorrow late night i.e. between 25th and 26th morning or 26th afternoon. 
Further, people, due you know how I am going to die, I would take the tablets which I had experimented on body to cure my POIS and this time I would take bundled of tablets to die. 100% I know that I would go directly only to heaven as I have done so much of help to others. However, people in my city would believe that I would go directly to helll as they completely mis-understood me and god only knows  my behaviour and what I am and why I am helping so much to others and because of my honest behaviour he is calling very early in my life
Further, while writing this and also while taking the tablets, I would be extremely happy and not at all sad as I am going to add and further I am satisfying so many peopleís wish as they want me to die.  If I give this death note to my people, no body would trut, thatís why I am giving this note to this forum, so that atleast you would trust. I am humbly requesting you to pray for my soul to go directly to god and also, please pass this message to poiscenter.com.
Unfortunately, I am leaving you people in the middle of the POIS research, sorry for the same as I promised so many people that I would be a part of the POIS cure team and I pray god to excuse for this mistake of me.

Thanking you,

Nathan

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Offline Thapelo

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19613 on: 24/07/2014 19:14:31 »
Hello, also an update from my side

I am taking anti depressvium at the moment, just to try it.
It is a low dosage, and i have to admit, that it helps a lot. My mental condition is far better now, i got a reduced down feeling moment the 2 days after ejaculation. But, i still got the problem i am not able to talk the next day, i have trouble remembering things, dizziness, and unexpected anger and anxiety.
I had these symptoms before taking the medicine, but wauw, it is in such a lower level.

Please share your experiences so we can make a progress.

Kind regards

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Offline nathan123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19614 on: 24/07/2014 19:15:34 »
I forgot add one thing in my last post, tomorrow one day, I would watch and read, life after death videos with full happiness.  Bye. Bye. to all

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Offline Thapelo

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19615 on: 24/07/2014 19:25:38 »
Nathan

i want you to read your inbox

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Offline vik1379

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19616 on: 24/07/2014 21:22:57 »
I forgot add one thing in my last post, tomorrow one day, I would watch and read, life after death videos with full happiness.  Bye. Bye. to all
Nathan, my friend, life is biutiful!
Please, find the power to be with us!
Better time is near!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19617 on: 24/07/2014 23:57:07 »
<former Moderator visiting periodically>

I forgot add one thing in my last post, tomorrow one day, I would watch and read, life after death videos with full happiness.  Bye. Bye. to all

Why bye bye, nathan??

We don't want u 2 go!!

Demo

« Last Edit: 25/07/2014 00:00:38 by demografx »

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Offline desperate man

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19618 on: 26/07/2014 23:19:20 »
Check this out guys: http://ghr.nlm.nih.gov/condition/dopamine-beta-hydroxylase-deficiency

DBH deficiency. One of the symptom is Retrograde Ejaculation. That's not all. It also explains my hypoglycemia and ADHD, low dopamine, droopy left eye, constant stuffy nose and muscle weakness.

Strange thing is that they state the symptoms start occuring in infancy. It doesn't make sence. Haven't found anything else that could match so much of my POIS symptoms as well as other POIS sufferers' symptoms.  [:-\]

Edit: I just read Nathan's post. Can somebody give us an update? Does anybody know him personally? Nathan please read about DBH deficiency and I also wanted you to read about Fructose Malabsorbtion.

Second edit: Thank B_Jim for reminding me about the sugar theory. Wanted to put together a huge PDF for this, but the research is far from done and considering cases like Nathan's I think it's best to share what's available so far. Just like DBH deficiency sharing very familiar symptoms of POIS it seems that Fructose Malabsorbtion comes as a close second. I might as well be hanged for a sheep as a lamb because we are not talking about the "ordinary" FM, but the very rare form appearing in infancy called Inherited Fructose Intolerance.

This is a very rare and serious condition shutting down the kidneys, destroying liver cells etc. and is often fatal, BUT not all the time! I have found a scientific journal of a female patient who was over the age of 50 when got diagnosed with this so there is hope. The reason for this theory is the following:

I share symptoms of Lyme disease, Chronic Fatigue Syndrome, diabetes you name it! I have yet to meet somebody that has a reaction to a sugar alcohol called SORBITOL.
It's in your sugar free gum, it's in your fruits and certain vegetables it's in your TOOTHPASTE and your semen (semen has fructose as well).
For years I would just do my routine of brushing my teeth and each time I brush my teeth it takes less than 2 minutes to start feeling shaky and experience severe burning in my stomach.
This burning cannot be alleviated by anything other than eating something.
When deciding to neglect this sensation it will lead to full blown hypoglycemia besides the burning in my stomach like if I drank acid.
My wife decided to buy me an all organic toothpaste just to find out it will cause the same reaction in me.
Because of this I tried to avoid brushing my teeth for a very long time and yes, my teeth are not pretty. Like I said, I yet to find somebody sharing the same symptoms as I do.

Over a year ago I decided to give Sublingual B12-s a shot and they did give me an energy for a few minutes when I started to exercise I became very fatigued and hypoglycemic, hungry.
One of my good friend (naturopath) suggested that it could be the sorbitol. I've put it down to "having Lyme Disease that causes POIS and all kinds of crazy symptoms".

It was lately when I looked into sorbitol again after brushing my teeth followed by a set of crying in the corner of the bathroom asking why me. You can be allergic to sorbitol or at least have an intolerance to it, but it didn't explain the rest of my issues.

Cherries, honeydew melon, watermelon, apples, bananas. These were my main diet the past few weeks along with chicken and rice (which I don't react to). The cherries and apples caused me the exact burning sensation in my stomach as did the sorbitol containing supplement and toothpaste. Still didn't make sence, because the organic toothpaste had Xylitol in it.
That's when the lightbulb went off and I found out about IFI (Inherited Fructose Intolerance) which includes sugar, sorbitol, mannitol, xylitol etc.

The reason why I write these long posts is that maybe someone might see him/herself matching these symptoms and could finally find someone suffering with the exact issues of POIS.
IFI causes Ejaculation Retrograde.

SOLUTION: Follow this diet and avoid everything that doesn't have two double green smileys next to them: http://www.food-intolerance-network.com/food-intolerances/fructose-intolerance/fructose-table-in-alphabetical-order.html

Do NOT use any substitutes with sugar alcohol like sorbitol, mannitol, stevia, xylitol etc. !!!

Do this for a week and report back to me of your overall health and symptoms of POIS (and if you can please give your body a break and try to abstain from ejaculation to approve this theory).

Thanks!


« Last Edit: 27/07/2014 00:03:53 by desperate man »

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Offline prism

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19619 on: 27/07/2014 12:02:59 »
I decided to suicide myself as I am not able to tolerate the life. This is my death note.

What a bad idea.
http://www.youtube.com/watch?v=OnrLULAryv0

« Last Edit: 27/07/2014 12:30:39 by prism »

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Offline PmbPhy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19620 on: 27/07/2014 14:38:37 »
Nathan - Take it from someone who has attempted to kill himself many times that this is not a good idea. I live with chronic pain. During the period when no doctor would give me pain medication due to their cowardice regarding fear of doing something wrong prescribing and get into trouble with the law, they won't prescribe narcotics. So I had to suffer horrible unbearable pain for close to a decade. It messed up my mind severely. The pain was so horrible it was like my body was torturing me horribly. So I know what it's like to want to die and I had a very good reason to want to kill myself. Unbearable suffering is one of the recognized ethical reasons to commit suicide. My mind was so messed up from the pain that it kept twisting my mind into having horrible thoughts. Some of those thoughts ended up in an e-mail and for 30 seconds of insane thinking I said something scary to someone. It was taken very seriously and I ended up in jail for almost 3 months waiting to go to court. And the pain was even worst than ever there. I was quite literally being tortured by my pain and no ability to seek help. The jail people could care less how much pain the people in jail are in. It was horrible!!!!  I never knew that they could allow prisoners to suffer like that. When I went before the DA and the judge everyone understood that it happened because I was suffering too much to deal with. I was put on probation for two years and then my record will be wiped clean. It helped because I had no criminal record in the first place.

That was what happened one time when I had suicidal thoughts. Other times had other severe problems. It's not as easy to kill yourself as you might think. All times failed and I ended up merely suffering more and more.

The good news is that I finally found a wonderful doctor and am now on pain medication that takes care of the pain sufficiently. I am now living life again and actually enjoying it! :)

If I were you I'd sit down with that jerkoff who started spreading that rumor and say something like this;

Nathan: Just who do you think you are? What ever gave you the impression that you had the right or the correct information to spread rumors about me? Are you so ignorant that you're completely unable to comprehend what severe damage you can do to a person's like when you start horrible rumors like that? It doesn't matter whether it's true or not. I don't want you to walk away from our talk today thinking that its okay to tell everyone who is and who isn't gay. I'll tell you again right now - I'm NOT gay.  Your horrible actions have caused severe problems in my life, to the point where I can't enjoy life anymore. What's the sense of living when so many people are harassing me because of the false rumor that you started about me? What motivated you to do something so horrible? Exactly how did you benefit by spreading this rumor? Is it because you wanted to be the first person to set loose the gossip and therefore get credit for it later on when you and your friends are sitting around getting drunk and laughing at my horrible fortune? I've said it before and I'll say it one last time, after which I want nothing to do with you. Never contact me again after this, ever! Now cut the crap and stop spreading this lie!!

You need to stand up for yourself. If you can't say it to their face then e-mail it to them or send them a letter, please! Before something horrible happens to you like it did to me.
« Last Edit: 27/07/2014 20:58:25 by demografx »

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19621 on: 27/07/2014 20:56:03 »
<Former Moderator visiting periodically>


Hello friends,
I decided to suicide myself as I am not able to tolerate the life. This is my death note. If I provide my death note to people in my city, no body would believe what I am saying. Thatís why I am providing my death note to this forum, so that atleast you guys would trust what I a a m saying and there would be a peace to my soul. Reason for sucide is as below
As posted in my previous post, people in my city are though that I am gay and they are spreading the message to all the people in the city. Further, my parents, my friends, my boss, my colleagues are under the assumption that I am Gay. With add to this, from the past several years, I am helping others too much and I am taking extra care of so many people and I am soft corner to all the people. Why I am doing this, for each help / each extra care / each soft care taking to others, I am praying with my god is that god please cure my POIS and see how I am helping to others. But people around me incluing my parents, my boss, my friends, thought that I am a gay and due to this, I am helping so much to others. But factually, as explained above, I am helping other because, I want to show god that how I am helping everyone and also with intention of my future business plant.  Due to this my too much helping nature along with POIS symptoms, people misunderstand me and they thought that I am a gay. Initially, I have around 500 people who had trusted me. But as of now, I not had even a single person who will trust me.  I not done even  a single mistake / harm to others and not seen any of them sexually except for one girl I loved her and later as she rejected had a quarrel with her and told many lies in this area and also I not taken care my parents and neglected them. Apart from this, I have not done a single mistake / error / bad behaviour in past 6 years of life. 
However, I confess that in my childhood, i.e. around 10 years back, I have done few mistakes in my life and I realized those mistakes and I never did such a mistake. As explained in my previous post, my astrologer has identified my childhood bad behaviour and he believed that I carrying that behaviour now also and spreaded bad message to my family. He not understand how I changed from 2005 and doing only good things in life and not at all scold any one even if they do any wrong thing, how helpful to others in teaching, giving jobs, giving money, solving problems without any much expectation except praying god for my care and also my future business help.
But, to all the people to whom I had helped, not understanding me.  Thatís why I came to a conclusion that people like me i.e. very sincere, honest, good, too much caring person is not possible to live in this commercial life, as people had different thing in thier mind and even thgough I had done good work with the intention, would not understand. Thatsís why I am realized that I am become too much honest and it is not possible to live in this world and also not possible to facIe POIS.  After my POIS cure, I had a dream of helping orphans. But now, I am leaving my life without achieving my objective i.e. to help orphans and unfortunately, now I am dying as a orphan even though I had so much of friends, parents etc and it is not of any oneís mistake. I also acknowledge my friends reaction to my behaviour as they are normaly commercial people and not abnormal like me where I helped too much to all that one no body would do in this era. So, I felt, my fate is not good and due to this, I am leaving my life at this young age of 26 and my death day is tomorrow late night i.e. between 25th and 26th morning or 26th afternoon. 
Further, people, due you know how I am going to die, I would take the tablets which I had experimented on body to cure my POIS and this time I would take bundled of tablets to die. 100% I know that I would go directly only to heaven as I have done so much of help to others. However, people in my city would believe that I would go directly to helll as they completely mis-understood me and god only knows  my behaviour and what I am and why I am helping so much to others and because of my honest behaviour he is calling very early in my life
Further, while writing this and also while taking the tablets, I would be extremely happy and not at all sad as I am going to add and further I am satisfying so many peopleís wish as they want me to die.  If I give this death note to my people, no body would trut, thatís why I am giving this note to this forum, so that atleast you would trust. I am humbly requesting you to pray for my soul to go directly to god and also, please pass this message to poiscenter.com.
Unfortunately, I am leaving you people in the middle of the POIS research, sorry for the same as I promised so many people that I would be a part of the POIS cure team and I pray god to excuse for this mistake of me.

Thanking you,

Nathan



www.suicidepreventionlifeline.org/
Nathan, P L E A S E  call 1-800-273-TALK (8255) you'll be connected to a skilled, trained counselor!

OR CALL IN THE UK:
08457 90 90 90

IN INDIA:
http://www.suicide.org/hotlines/international/india-suicide-hotlines.html


We are not professionally equipped to help here!

Best,
Demo

« Last Edit: 29/07/2014 04:12:14 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19622 on: 28/07/2014 01:32:36 »
<Former Moderator visiting periodically>


POSTED BY "PRANCER" AT POISCENTER.COM

There's no need to end your life early Nathan. Life's short enough already! Enjoy life as much as possible and avoid or ignore those that piss you off. Only be around people you like and are comfortable with. Also, if people you know get upset because you're helping others too much, then they're what most people would refer to as: total MORONS! Who would be mad at someone who helps people!? People with room-temperature IQs, that's who.

You can consider moving to a new city if everyone is so mean to you all the time. Just don't make suicide an option because it's not worth it. Enjoy living life, make new friends and have a good time!

Prancer

« Last Edit: 28/07/2014 01:36:59 by demografx »

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Offline Nightingale

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19623 on: 28/07/2014 04:23:00 »
Where I come from, some people believe in astrology. Some seriously. I am not one of them, so I cannot talk to you Nathan as someone who understands it.

But I will tell you I live in a place where people aren't ashamed of being gay, or often have awkward but usually funny conversations with people who thought someone was gay but were mistaken! I have friends who are gay, and they all are accepted by MANY people, and MANY people think they are COURAGEOUS people for being openly gay!

I actually recently had a neighbor not far up the street from me speak to my roommate about me. My roommate is a man, and I rent from him, and most of the time people just see our cars in the driveway. My roommate has a girlfriend who lives 2 hours away by car, and she rarely stays at our home but instead my roommate travels to her. So naturally our neighbor was curious, and asked if I were my roommate's "partner"! It was a pure, innocent question, and my roommate got a little embarrassed, but he explained the situation and he and the neighbor had a good laugh! I did too, when my roommate told me the story! People are changing, and they recognize that not everyone is heterosexual, and our neighbor was one of the brave ones to try and invite us to tell them we were gay if we were. We are not, but I am proud of my neighbor for not stigmatizing being gay!

It's a shame people still think of people as "a gay", like they are something so different, like "a black", "a white". I believe, and with good evidence and reason, that being gay is NOT A CHOICE, and that it is something you are not responsible. I did not choose to be straight! Life made me that way. Life made a few of my friends gay, they don't have a choice in this! So there is no way to feel guilty or shameful, there is no way to be different, and NO REASON TO!

So, if you, or anyone else here are being harassed for being gay, KNOW WHAT YOU BELIEVE YOURSELF TO BE AND BE PROUD OF IT. YOU WERE BORN THAT WAY!

Nathan, I really do hope you are reading this. I've lost friends before this way, and seen friends saved from an ending like this. You, and anyone else reading this, I AM PROUD TO BE ASSOCIATED WITH ALL YOU BRAVE MEN WHO ARE FIGHTING THIS ILLNESS, STRAIGHT OR GAY, WHITE TO BLACK, CRAZY OR CALM! I TAKE SOLACE KNOWING I AM NOT ALONE IN MY PAIN, AND KNOW I SUPPORT YOU ALL!

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Offline romies

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19624 on: 29/07/2014 04:32:09 »
Nightingale,

Good to see you back. I read your article on dopamine and I admire your guts in undertaking electroconvulsive therapy. I am glad that it is working for you.

I remember that you have MAOA R279R (+) http://snpedia.com/index.php/Rs6323
Usually this variant causes dopamine level too high, and results in psychosis.
Also this variant make it very hard for you to tolerate 5htp supplement, because you may quickly go from deficiency to excess on serotonin.

There is a medicine that directly correct this problem for some people: http://www.respena.com/respen-A/respenAclinical.pdf
that increase MAOA activity specifically.

Antipsychotic medicines typically just block dopamine D2 receptors in the brain without actually lowering the dopamine levels.

I also recommend running this report on your 23andme results: http://www.snpedia.com/index.php/Promethease

It has lots of information on what medicine may or may not work for you due to your genetic make up. For example, my dad was able to switch to a more effective medicine for his bipolar disorder, after we found his genetics does not properly transport several SSRI over the brain-blood barrier, including the med he has been taking for years. Now he can take a much lower dose on a more effective med.

Also, this diagram may be helpful to you to see what neurotransmitter you are deficient: http://en.wikipedia.org/wiki/File:NorepinephrineDopamineSerotonin.png

Romie S
« Last Edit: 29/07/2014 04:58:26 by romies »

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19625 on: 29/07/2014 04:50:28 »
My update:

It's been a while since I post my progress, since life has been very busy.

In short, I am doing much better, having POIS under a manageable control: I do not worry about having orgasm any more (a big plus for my relationship with my partner)

Unless I have too many orgasms (twice a night straight for 2+ days), I have no more cognitive problems.

My daily regimen is now simplified to:
morning: Vitamin D, MethylGuard(1 capsule), Ginkgo Biloba extract (1 capsule), Fish Oil
vyvanse for my ADHD

before sleep: ZMA (1 capsule, to get some Mg and Zn), Vitamin C (100mg)

For the days I have orgasms, I take 1 tab 12-hr 100mg 5-HTP and NADH before sleep
I also take 1 capsule of NADH, and 100mg of Tyrosine upon wake-up the day after.

My main problem is low BH4 from A1298C variant, that makes me low in dopamine, Norepinephrine and seretonin. 5-htp helps on replenishing serotonin, and tyrosine helps on replenishing dopamine.
Vitamin C helps converting Dopamine to Norepinephrine

I realize that I also have low Norepinephrine, after realizing my POIS symptoms can be completed eliminated by taking a 24-hr Claritin-D (even if I need to take it right before sleep). Interestingly, the active ingredient is actually pseudoephedrine, that stimulate the release of Norepinephrine in brain. However, pseudoephedrine has a lot of other side effects, and depletes dopamine in my brain, so I don't take it as a long term solution.

5-htp can be converted to serotonin without consuming Bh4, which I need to save for dopamine...


Notice: there are many causes of POIS, and what works for me is probably only relevant to people with low BH4 (+ low dopamine and serotonin)



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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19626 on: 29/07/2014 04:55:25 »
Check this out guys: http://ghr.nlm.nih.gov/condition/dopamine-beta-hydroxylase-deficiency

DBH should be diagnosable through blood testing of Norepinephrine and epinephrine, coupled with genetic testing such as 23andme.

Those symptoms listed can be also caused by many other reasons, such as A1298C mutation, that reduces L-dopa level (a necessary ingredient to make Dopamine, Norepinephrine, epinephrine)
http://mthfr.net/mthfr-a1298c-mutation-some-information-on-a1298c-mthfr-mutations/2011/11/30/
http://www.snpedia.com/index.php/Rs1801131


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Offline desperate man

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19627 on: 29/07/2014 13:03:15 »
I know MTHFR inside and out, because I've worked with Dr. Lynch before and my work consists of researching (which I rarely do successfully nowadays bc of compulsive masturbation followed by POIS and low dopamine).

I also suggest looking into COMT since you are familiar with 23andme. It will lead to adrenal burnout in the long run. Royal jelly will help increase BH4 production.

Been there, done that. Vitamins, minerals from A-Z. Methyl B-s, digestive enzymes, probiotics etc.
Nothing worked besides L-Tyrosine which gave me severe anxiety so I stopped it.

Now I suspect longterm iodine deficiency. So I decided to give it a shot, but it made my blood sugar problems worse. It is because my adrenals are out of whack and I'm in overdrive from the COMT.
Going to follow this guy's dietary protein/carb ratio suggestions: http://ehealthforum.com/health/proteins-trigger-low-blood-sugar-t185956.html followed by megadosing of vitamin C (5-10 g /day), spending less time on the computer and going to bed earlier as well as limiting ejaculation. I've also ordered Skullcap and going to up my magnesium intake. If things will get better then I will give Iodine another shot. I think it's the root cause of my chronic anemia and it's worth mentioning.

PS: Anyone tried taking glucose tablets before or after orgasm? How did it affect you?
« Last Edit: 29/07/2014 14:28:52 by desperate man »

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Offline romies

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19628 on: 29/07/2014 17:53:54 »
I know MTHFR inside and out, because I've worked with Dr. Lynch before and my work consists of researching (which I rarely do successfully nowadays bc of compulsive masturbation followed by POIS and low dopamine).

I also suggest looking into COMT since you are familiar with 23andme. It will lead to adrenal burnout in the long run. Royal jelly will help increase BH4 production.

Been there, done that. Vitamins, minerals from A-Z. Methyl B-s, digestive enzymes, probiotics etc.
Nothing worked besides L-Tyrosine which gave me severe anxiety so I stopped it.


It is great that you investigated MTHFR completely. My personal experience is my genetic makeup is only part of the whole equation and I try to get more lab testing (blood or urine if possible) to find out the real levels of various vitamin/neurotransmitter metabolite in me.

Now I suspect longterm iodine deficiency. So I decided to give it a shot, but it made my blood sugar problems worse. It is because my adrenals are out of whack and I'm in overdrive from the COMT.
Going to follow this guy's dietary protein/carb ratio suggestions: http://ehealthforum.com/health/proteins-trigger-low-blood-sugar-t185956.html followed by megadosing of vitamin C (5-10 g /day), spending less time on the computer and going to bed earlier as well as limiting ejaculation. I've also ordered Skullcap and going to up my magnesium intake. If things will get better then I will give Iodine another shot. I think it's the root cause of my chronic anemia and it's worth mentioning.

PS: Anyone tried taking glucose tablets before or after orgasm? How did it affect you?

Lont term iodine deficiency can be tested with thyroid hormone levels and iodine levels directly.

Glucose levels: have you try to measure your blood glucose level with a home glucose meter? 5 years ago I suspected low blood glucose as a reason for my POIS as well, but my test shows my level pretty much the same on POIS and non-POIS days (+-3%). It is pretty easy to test that out.

BTW, I also found magnesium helpful for me. I am in the US and generally US diet is magnesium poor.

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Offline romies

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19629 on: 29/07/2014 20:35:25 »
I also suggest looking into COMT since you are familiar with 23andme. It will lead to adrenal burnout in the long run. Royal jelly will help increase BH4 production.

I am MAOA R297R(-), COMT V158M(-/-), COMT H62H(-/-) and VDR Taq(+/+), a typical case of low dopamine. I've posted my entire methylation profile here before.

You said you had severe anxiety from Tyrosine. I wonder if you are low on serotonin as well, since serotonin also needs BH4, VB6 and others (very similar to Dopamine) to be produced from tryptophan.

For me, taking 5-htp (12hr time-released) increase my serotonin, calms me down from anxiety, and gives me more energy (by channeling bh4 for dopamine generation).
Serotonin does not require COMT to be metabolized, so likely you are fine.



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Offline Nightingale

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19630 on: 30/07/2014 00:27:04 »
Nightingale,

Good to see you back. I read your article on dopamine and I admire your guts in undertaking electroconvulsive therapy. I am glad that it is working for you.

I remember that you have MAOA R279R (+) http://snpedia.com/index.php/Rs6323
Usually this variant causes dopamine level too high, and results in psychosis.
Also this variant make it very hard for you to tolerate 5htp supplement, because you may quickly go from deficiency to excess on serotonin.

There is a medicine that directly correct this problem for some people: http://www.respena.com/respen-A/respenAclinical.pdf
that increase MAOA activity specifically.

Antipsychotic medicines typically just block dopamine D2 receptors in the brain without actually lowering the dopamine levels.

I also recommend running this report on your 23andme results: http://www.snpedia.com/index.php/Promethease

It has lots of information on what medicine may or may not work for you due to your genetic make up. For example, my dad was able to switch to a more effective medicine for his bipolar disorder, after we found his genetics does not properly transport several SSRI over the brain-blood barrier, including the med he has been taking for years. Now he can take a much lower dose on a more effective med.

Also, this diagram may be helpful to you to see what neurotransmitter you are deficient: http://en.wikipedia.org/wiki/File:NorepinephrineDopamineSerotonin.png

Romie S

Cool. Thanks for the reponse.

I have run Promethease before, I don't recall any obvious changes I needed to make but it's been a while so it wouldn't hurt to run it again.

This homeopathic you recommended... I have no idea how I am to obtain that if I need a prescription without finding a doctor who would have an understanding of homeopathy. I personally don't understand it, but if there's a chance it would help I'm still curious. It does say that its designation is officially as an anti-hypertensive, which is a danger sign for me. I have had bad reactions to most meds that even make that effect in a small way.

I hate taking meds, I honestly do. I'm lucky to have found a few that I can actually tolerate daily. But things are not where I'd like them to be. I'll check with one of those doctors they list on their website if I don't respond during the research trial. I really do think that the neurotransmitter theory of mental health is flawed, and that understanding neural circuits and their function is going to fill in the holes in our comprehension of our mental health. Obviously, it is an important piece, but it's a dangerous one for me to experiment with.

I need to weigh this one out more. Thank you for the help, and I'm thrilled to hear you've found relief!
« Last Edit: 30/07/2014 00:31:07 by Nightingale »

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Offline desperate man

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19631 on: 01/08/2014 12:25:55 »
My naturopath friend told me that my norepinephrine is too high and it doesn't convert to adrenaline. This causes adrenal insufficiency which would explain the daily struggle with hypoglycemia and the chronic fatigue, Lyme symptoms.
I don't know what's the truth behind this.

By the way I've read a thread on Longecity about a guy who were experimenting with nootropics and found out that increased norepinephrine will make you stupid. That's exactly how I feel. If I go for a week without ejaculation I feel intelligent with personality changes for the better but then again I've never checked my neurotransmitter levels before so all this is just hypothesis based on symptoms.

By the way BH4 not only makes serotonin but dopamine as well.

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Offline GDR

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19632 on: 02/08/2014 04:07:21 »
Hi everyone. It has been a while since I have written something here. A couple of new developments for me. I am finding some definite relief in taking garlic oil capsules. I take a lot so I hope in the long run there is no health effects. At the moment I am using a regime of Vit B12 (methlycobalamin), Vitamin D3, garlic oil, L-Arginine, Chlorella and chia seeds. For the first time in years I am actually getting a proper erection. I also have something very curious happening to me after orgasm which I have never read before. On either side of my head in the exact spot I am feeling a tender spots. There is some slight relief as far as inflammation is which for me more than anything is photosensitivity (burning sensation of the eyes). I live in Taiwan where good acupuncture is available at cheap price so this is a path I will explore asap. I also find 5-HTCP to be hugely beneficial to me. I also keep the zn and mag supplements going as well. My discomfort has been reduced by 40-50%. Keep the good work moderators!

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19633 on: 02/08/2014 13:27:59 »
Hello,

I too used to have this issue. It began when I was 22 years old.  When I was 28 years old, I began experiencing terrible nausea and prostatic pain. When my Urologist could not find any sort of infection and no reason for the pain, I began experimenting with antifungal herbal remedies and over-the-counter medications. My pain went away and so did the POIS. I believe that the POIS was a result of yeast strapped inside my prostate and when I had an orgasm, my prostate released immediate fungus into my body and my immune system reacted to it. I believe this reaction caused the extreme fatigue, lethargy, dizziness, brain fog etc. Once in a while I still have POIS but it is never as bad as it used to be when I was younger. I also stay away from yeast-based foods such as breads, cheese and nuts. If this does not work for you, I read a few months ago about a man in his 60s who had terrible POIS and it turned out he had low levels of the hormone Progesterone. The man's POIS was also cured.

Good luck!

   
« Last Edit: 02/08/2014 13:34:44 by George10 »

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Offline desperate man

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19634 on: 02/08/2014 23:41:17 »
Thank you for bringing up L-Carnitine. What kind of experiences do you guys have with it?
I'm willing to try it even though it warns against ingestion by people with poor glucose tolerance I really don't care anymore.
Wife was acting funny for too long and now found out that she's a pathological liar. My work has gone downhill and I'll most likely be replaced by someone that can put 100% focus on doing my job.

If this fails then I will sell all my belongings and leave my country in hope of becoming a Buddhist monk. I feel the exact same way as Nathan did, but I've attempted suicide once and it didn't work out.
I might as well be free from women, sex, masturbation and anything my body was not designed for. Life is too precious and we have a reason to live.

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johanstefansson

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19635 on: 03/08/2014 18:45:33 »
Here is something interesting...

Had my ejaculation on Saturday the 26th July. Hell broke loose on Sunday with severe depression, however flu symptoms was delayed until Friday, quite strange actually.

This is quite different from earlier, usually the flu symptoms are more immediate... not this time.

Guess it took some time to brake down my immune system this time... was quite long time since last ejaculation. I have been on holiday and got lots of sun. Eaten well too. Its what I can think off.

What do you guys think is the reason for this partially delayed symptoms?

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Offline Defsync

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19636 on: 04/08/2014 05:40:41 »
Hello peoples.

I have returned with a small bit of useful info.

I have found a new regiment thats really helped me stave off unwanted nocturnal emissions.

I consume one Monster Energy Java drink a day. Thats it. Now how does this work? Not sure why this particular energy drink is so potent, but it seems to noticeably "desensitize" one as well as lower the sexual urge. I used to use dream control and take a muscle relaxer etc etc. For whatever reason though drinkin one of those Monster Java energy drinks a day has made avoiding NE's so much easier. Im not gonna even begin to dissect the reason, I just know that it works fairly well. Also relieves minor aches and pains, this particular brand of energy drink, so might be helpful for those who have O'ed as well? Anyways, fight the good fight. Im out. Peace.

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Offline B_Jim

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19637 on: 04/08/2014 06:32:10 »
Hello peoples.

I have returned with a small bit of useful info.

I have found a new regiment thats really helped me stave off unwanted nocturnal emissions.

I consume one Monster Energy Java drink a day. Thats it. Now how does this work? Not sure why this particular energy drink is so potent, but it seems to noticeably "desensitize" one as well as lower the sexual urge. I used to use dream control and take a muscle relaxer etc etc. For whatever reason though drinkin one of those Monster Java energy drinks a day has made avoiding NE's so much easier. Im not gonna even begin to dissect the reason, I just know that it works fairly well. Also relieves minor aches and pains, this particular brand of energy drink, so might be helpful for those who have O'ed as well? Anyways, fight the good fight. Im out. Peace.

=> Taurine (423mg) ?

The legend is these energy drinks are made with bulls semen. It's funny.
But taurine may be the ultimate key for Pois explanation.

Each time I eat fish like salmon, my Pois symptoms are much lower. . I don't have muscle twitch when I eat lot of fish. After ejaculation, my muscle twitching is maximum. Taurine is present in human semen, even if in very low level.
I have posted some testimonies like this one . We have a woman member in the PoisCenter saying his husband has good improvement with taurine supplement (even if 1.5g a day is too much, 500mg a day seems safer)
I tought it was vitamin D. But vitamin D supplement don't really help.
I tought it was astaxhantin. Once again, astaxxhantin 4mg supplement didn't work.
I tought it was omega 3 (sperm is rich in DHA). Maybe DHA is involved but the fact is oil fish doesn't really help.
So what is the secret of fish ?

There is few taurine in fish oil, only in whole fish !

fish standard : 90 mg per 100g of dry product
capelin : 143
salmon : 130
mussels : 665
mackerel : 207
pork leaver : 90
oysters : 70
beaf standard : 35
yoghurt : 3.3
energy drink : 400 to 1000 (Red Bxxx) per can

I never drink energy drink anyway.

Too much taurine is a problem but not enough is a problem too. It's not a magic elixir but it's worth to boost the levels in blood to show its influcence or not on Pois.
300-500mg to 1000mg (not more) seems correct.


Welcome back Nathan !
« Last Edit: 06/08/2014 20:11:52 by B_Jim »

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Offline nathan123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19638 on: 06/08/2014 06:10:27 »
Hello all,

As explained in my previous post, I attempted for bad thing on 26th, after taking those tablets, I realized importance of my life and our goal to remove POIS. Fortunately, I survived from my attempt and I was in ICU for two days and now back to normal life.  Presently praying god for a good job as I lost my previous job.  Thanks for the support provided to me.  I would be back again on trying things for cure at the earliest. 


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Offline Nightingale

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19640 on: 07/08/2014 05:34:57 »
Hello all,

As explained in my previous post, I attempted for bad thing on 26th, after taking those tablets, I realized importance of my life and our goal to remove POIS. Fortunately, I survived from my attempt and I was in ICU for two days and now back to normal life.  Presently praying god for a good job as I lost my previous job.  Thanks for the support provided to me.  I would be back again on trying things for cure at the earliest. 

Hi Nathan :)

Best thing I've read in a long while... :):):) Let us know how your job search goes, ok?

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Offline Jonas STHLM

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19641 on: 12/08/2014 12:25:50 »
I am a little bit curious to know if any of you have tried neuro feedback?

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johanstefansson

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19642 on: 13/08/2014 13:27:29 »
http://psychcentral.com/lib/the-vicious-cycle-of-adult-add-shame-and-compulsive-sexuality/000520

that is me in a nutshell. haven't been porn surfing for some years now but i think it has alternated my mind significantly, never seen prostitutes thank god. i think my tinnitus boosted my problems significantly.

my parents have never really acknowledged my talents, thats really a shame, they also made me isolated as a young adult.

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Offline Kima

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19643 on: 13/08/2014 20:14:02 »
Who tried to take large doses of nicotinamide? Helps symptoms disappear?

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Offline Omen 30

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19644 on: 14/08/2014 20:17:14 »
i am on a casein free(dairy free) diet since a year and it had helped me a lot,and with that i take vitamin d supplement not daily but once in 10-15 days around 5000-10000iu.try it friends it has helped me a lot.

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Offline desperate man

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19645 on: 15/08/2014 01:21:32 »
http://psychcentral.com/lib/the-vicious-cycle-of-adult-add-shame-and-compulsive-sexuality/000520

that is me in a nutshell. haven't been porn surfing for some years now but i think it has alternated my mind significantly, never seen prostitutes thank god. i think my tinnitus boosted my problems significantly.

my parents have never really acknowledged my talents, thats really a shame, they also made me isolated as a young adult.

It doesn't surprise me, buddy. The problem with POIS is that it's based on theories. Hundreds, thousands of theories. That article hit home. Our theories always start from people experiencing POIS.
What if we set a baseline and go from the ones who have a lack of experience with this devastating condition and say "it's all in your head"?

What if masturbation, ejaculation is normal and the problem lies in having an addictive personality? What if porn and compulsive masturbation are like HEROIN to us? What if our brain is wired differently because we had ADHD since a young age and been introduced to masturbation, magazines and porn as a child therefore it is the only thing that gives us that rush, that high which when ends, we suddenly awake to a cold and cruel world that our brain with lack of dopamine cannot appreciate and value? A sudden increase of prolactin for POIS and depleted DA levels for addictive behavior.

Started looking into genetics again. I want you to list me your lab tests of the following things:
- L-Tyrosine
- Iron
- Copper/Zinc
« Last Edit: 15/08/2014 01:26:16 by desperate man »

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Offline randomuser784

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19646 on: 15/08/2014 01:29:24 »
I have only recently begun getting serious symptoms that prompted me to do some research and it looks exactly like POIS to me so far but the odd part is that I do not get any of the symptoms when masturbating, only after actual sex.

About 30 minutes after sex I get fatigue so serious that I have trouble keeping my eyes open and my mind feels so clouded I have trouble responding to things quickly or keeping a car on the road and even walking some of the time. I feel sick to my stomach to the point that it feels as if I may throw up but have not yet. Sometimes slightly pounding headaches happen as well as difficulty concentrating, difficulty thinking of the right words while speaking to someone and so on. Basically a bit of all of the symptoms with the fatigue and nausea being the worst.

EDIT:: The symptoms are all there even if I have been awake all day or just woke up, ate food recently or ate nothing.

It does not last as long as it seems it normally does though, either. The shortest recovery so far was 8 hours and the longest so far a day and a half, but that is still plenty of time to ruin appointments, work and other day to day events.

So does anyone else here only get it after actual sex and can still masturbate fine? Do any of you happen to know of anything else that matches this better than POIS since I can't seem to find any cases of POIS only after sex? The only other thing I can seem to find that is close would be anaphylaxis in response to an unknown condom allergy but that seems to be a very serious reaction and it seems unlikely that I would be getting such a lesser version of it.
« Last Edit: 15/08/2014 01:32:28 by randomuser784 »

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Offline desperate man

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19647 on: 15/08/2014 23:42:32 »
I've been suspicious about personality issues responsible for POIS, but today further strengthened this theory. Get this; I ended up watching a youtube video about POIS and there was a guy in the comment section praising everyone because he thought he was alone in this condition all these years, and now he found people with the same issues. Wanted to send him a PM, but after clicking on his profile I saw that he likes the exact same fetishes a sane person would not like. He also has the same taste of music as me and this is a spanish guy thousands of miles from here. Wtf? I'll try to get a halt of him to discuss childhood traumas and other health problems for further evaluation. I am still shocked. There's another guy on POISCENTER (not naming him) who I consider the most desperate person looking to have a life without POIS, who added me as his friend on facebook but couldn't deal with the amount of PORN he shared publicly. It was truly sickening and embarassing.

So in cases like these one thing we can all agree on: supplements will NOT fix anything. The issue can arise from rare genetic conditions, childhood traumas, head traumas and personality disorders. I truly feel this is going to be a milestone for those who's POIS is related to the conditions mentioned above.

People like these need to have amino acid profiling and neurotransmitters and 23andMe done. Then we can go from there.
« Last Edit: 15/08/2014 23:56:30 by desperate man »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19648 on: 16/08/2014 02:03:21 »
<former Moderator visiting periodically>


Hello peoples.

I have returned with a small bit of useful info.

I have found a new regiment thats really helped me stave off unwanted nocturnal emissions.

I consume one Monster Energy Java drink a day. Thats it. Now how does this work? Not sure why this particular energy drink is so potent, but it seems to noticeably "desensitize" one as well as lower the sexual urge. I used to use dream control and take a muscle relaxer etc etc. For whatever reason though drinkin one of those Monster Java energy drinks a day has made avoiding NE's so much easier. Im not gonna even begin to dissect the reason, I just know that it works fairly well. Also relieves minor aches and pains, this particular brand of energy drink, so might be helpful for those who have O'ed as well? Anyways, fight the good fight. Im out. Peace.

Monster drinks have 400% more caffeine than same size Starbucks.


« Last Edit: 16/08/2014 03:24:10 by demografx »

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19649 on: 16/08/2014 02:48:24 »
Randomuser - You are doing a lot better than many here if you can get over your pois in 8-35 hrs. It used to take me about 5 days when I was younger and now I'd say its 3 days (depending on how run down I am at the time).

As for pois and sex. For me pois is less after sex compared to masturbation. That's clear cut, and reading a number of stories here of others its also the case. I think the over stimulation from porn accounts for some/much of that imo. Condom allergy is irrelevant considering masturbation or wet dreams or in some cases even just looking at porn (no touching) can result in pois to various degrees for many here.