[demografx]

I had hyperprolactinemia (10x the ref range!) and I self cured it - with endo approval - by quitting reglan, which I read about in wikipedia. Yes, that's prolly why MRI was ordered.

[Dean93]

Hey Ambient, are you aware of this?

http://www.neuroassist.com/neurotransmitter-depletion-5-HTP-Depletes-Dopamine.htm

[ophicus1213]

I am new to this forum, and term Pois.  I am actually pretty excited that I found you guys because I didnt think there was anyone else out there.  I have been a suferer for a decade now, and I striving to heal myself.  I originally tried five years ago with a physician, urologist, and endocrineologist who offered nothing.  I ended up settling for an SSRI prescription that only yield results for a couple of weeks.  Now, I am back on the hunt and over the course of the last month I have tried nearly every amino acid precussor of the 4 main neurotransmitters.  I do also suffer from PE, and it is my main focus.  After undergoing hours of research, my main focus is now on lowering histamine levels.  I was benefiting slowly from SAM-E, L-trytophan, and L-Tyrosine, and Gaba.  Last week I decided to add Clarinex to my cocktail, which changed things for me dramatically.  I have noticed since the addition my body is craving much more L-Tryptophan.  My Pois Is 75 percent better on Sam-e and clarinex. 

[demografx]

ophicus1213, welcome to the POIS thread of The Naked Science Forum!



Congratulations and thanks much for sharing the good news on your 75% improvement with Sam-e and clarinex!

Here are some POIS resources which may be helpful to you:

Our new POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

If you want a copy (PDF), send me a Private Message with your regular email address and I'll send you back the PDF.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show the medical world - which often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community. This can help fight the immediate reaction of some: IT'S NOT "ALL IN OUR HEADS"!

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum for nearly 3 years, which has attracted over 150 POIS sufferers worldwide who have posted here, plus more than 400,000 page visits. Not bad for a rare malady!

[demografx]

ophicus1213, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: over 2 years' worth of posts from 150+ Forum members, and an additional 150 POIS sufferers found on the Internet, but not on this forum.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://www.thenakedscientists.com/

for example, I tried
demografx POIS site:http://www.thenakedscientists.com/

and 1,000+ results came up for "demografx" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

[demografx]

Watson Pharmaceuticals

Slight snag resolved today. My letter, plus attachments, was sent 3X, and was only retrieved successfully today when I called.

Our contact promised to write up a possible POIS study scenario and send it on to a company committee that meets several times a year for consideration.

I wrote again today asking when I can call to follow up with Watson to see what our status is.

[demografx]

I originally tried five years ago with a physician, urologist, and endocrineologist who offered nothing.

Sadly, that is an all-too-common experience for most of us. We're working hard to change that, and we are succeeding!  []

[hurray]

Watson Pharmaceuticals certainly sounds like they are taking POIS seriously. Excellent news, Demo!

[CertainlyPOIS]

i just have a question on reasearch.
where do you start when doing reasearch for pois.

[demografx]

CC, good question. We'll find out when we get a researcher  []

[demografx]

Watson Pharmaceuticals certainly sounds like they are taking POIS seriously. Excellent news, Demo!

Many thanks, hurray! Keep in mind it's a giant corporation and as such, takes its time, and will need multiple staff approval.

But so far so good!! (And it doesn't hurt that I'm a walking testimony to their product working!)

************************************************************

By the way, I'm still pinching myself to see if I'm awake: since I increased my testosterone dose 50% AFTER hitting normal T-range, and supplemented that with a Day Zero increase in stimulants...I'm practically POIS-free now! 

It is simply unbelievable after 30+ years of wretched, ugly POIS!

I sincerely hope that this gives much hope to others!

[Looking_for_answer]

My POIS treatment

Lately, I've been able to maintain almost 100% POIS-free episodes (increased testosterone and increased adderall). Can't really explain it (the near-100%). Maybe the treatment is catching up and is in effect a "wholesale cure"!

Today, when Day Zero symptoms started creeping up, I forced myself out into the sunshine...and it worked! (My natural tendency on Day Zero is to maximize physical/mental passivity). Simplistic? You bet! []

i believe there is fundamentally nothing wrong with us and drugs are just a quick way out.

Very interesting point of view, not sure I agree.


Anyone else have a thought about that?

Personally i think there is something wrong with us and that thing was dormant untill excessive pleasure aggravated. Untill we can find out what is wrong we dont know if drug will be a quick fix or it will take longer.  

Yes ok by 'fundamentally wrong' i mean something like a genetic deffect or something like that, ie that probably needs pills for life (for example, bad eyesight needs glasses/contacts for life or surgery). But i dont exclude that we might have had a dormant problem for quite some time before symptoms appeared, I just mean that i believe it can be cured by natural means.

For example, suppose that as a kid someone is (asymptomatically) chronically dehydrated, or drink milk every meal, or his mother had low zinc levels during pregnancy, or had some digestive issues because some enzyme werent produced sufficiently, etc and end up with a low level of zinc. then it would be dormant for a while and would only get exposed after many ejaculations. i would not call that a fundamental problem, but rather a fixable problem.

dont forget that pharmaceutical compagnies only want to make profit (duh) so they will tell you of a cure only if they can sell u enough pills, ie u arent made aware of possible natural treatment and u likely end up with a life pill requiremnt, not a short pill treatment (like antibiotics). im too young to accept that sentence already.

[Looking_for_answer]

As anyone tried to taste zinc tally?

[Looking_for_answer]

My POIS treatment

Lately, I've been able to maintain almost 100% POIS-free episodes (increased testosterone and increased adderall). Can't really explain it (the near-100%). Maybe the treatment is catching up and is in effect a "wholesale cure"!

Today, when Day Zero symptoms started creeping up, I forced myself out into the sunshine...and it worked! (My natural tendency on Day Zero is to maximize physical/mental passivity). Simplistic? You bet! []

sorry if im confused, by day zero do u mean in the hours after sexual activity? and were you in the sun enough to actually see a change in skin color?

[hurray]

Good to hear that you are still getting the better of POIS, Demo! My Fenugreek has all but killed the social anxiety component of POIS I used to suffer from, and as a bizarre side-effect my hair is always really glossy and lustrous - well, I'm not complaining

Like you Demo I am cautiously optimistic about the latest developments. But I think Watson could do very well from researching a POIS drug. Although many posters here suffer POIS acutely, I believe that POIS is a sliding scale, and potentially millions of people may suffer from a milder form of POIS which could also be treatable.

If you posed the question "Have you ever suffered from sexual exhaustion?" to 100 people, I bet a reasonable number of them would answer "yes".

[Looking_for_answer]

ok last post for now.

if people wish, we could have a post with symptoms that everyone could quote and add all of his own health problems, even the ones he believes are totally unrelated to POIS and equally "embarrassing", like having testicules that shrink too much at the gym. Then if someone is computer litterate enough, we could turn the lists of all problems/symptoms into a survey in which we could vote on each item that affect us. End result would be a huge list of health problems/symptoms and their frequencies among POIS sufferes.. we could have surprises.


i was trying to make a short list myself, so i was reading page 247. i saw adrenal/chronic fatigue, immune system deficiencies, low testosterone, concentration/memory issues. i know im annoying with my zinc but i cant help to notice that these are the main effect of a zinc deficiency. Also 2-3 members on that page talked about alcolism, one of the leading cause of zinc deficiencies. I think a survey as mentionned above could really help. and every new member, in the introduction message, could be invited to take part in it. so it would keep evolving.

[demografx]

My POIS treatment

Lately, I've been able to maintain almost 100% POIS-free episodes (increased testosterone and increased adderall). Can't really explain it (the near-100%). Maybe the treatment is catching up and is in effect a "wholesale cure"!

Today, when Day Zero symptoms started creeping up, I forced myself out into the sunshine...and it worked! (My natural tendency on Day Zero is to maximize physical/mental passivity). Simplistic? You bet! []

sorry if im confused, by day zero do u mean in the hours after sexual activity? and were you in the sun enough to actually see a change in skin color?

Yes and no.

[demografx]

LFA,

1. Have you read through our previous discussions about zinc?
http://www.google.com/search?q=zinc+POIS+site:http://thenakedscientists.com&ie=UTF-8&oe=UTF-8&hl=en&client=safari

2. Did you see our online POIS survey questionnaire to see if you can recommend adding to it?

Both were discussed in your welcome post.

[hurray]

Welcome new sufferers .
We exceeded the number of 300 cases.
Hi, hurray. It's amazing that fenugreek helps you with social anxiety.    
It would be nice to talk about this with other social anxiety sufferers (Non-Pois).
Do you take 3 caps a day every day or just after ?
I will retry fenugreek extract after glutamine test.

I take one cap of Solgar Fenugreek (370mg raw fenugreek seed powder, 150mg fenugreek seed powdered extract) every day while in POIS, although I will often take it outside POIS for its positive social effects. I also take a couple of caps before and after orgasm as a precaution, it does help with the immediate after-effects but it isn't a 100% cure.

Fenugreek is supposed to help the body produce oxytocin (it is used by nursing mothers to encourage milk production) which could explain its effects - another theory is that it is a precursor to estrogen, which is thought to enhance sociability.

Good idea B_Jim - you would imagine that social anxiety sufferers would have discovered fenugreek themselves, but a quick google search didn't bring much up. Perhaps I should join a forum and ask around.

[CertainlyPOIS]

Welcome new sufferers .
We exceeded the number of 300 cases.
Hi, hurray. It's amazing that fenugreek helps you with social anxiety.    
It would be nice to talk about this with other social anxiety sufferers (Non-Pois).
Do you take 3 caps a day every day or just after ?
I will retry fenugreek extract after glutamine test.
---
I had an orgasm 3 days ago and I catch a cold the day after... There is really something wrong with immune system.
The tempeartures are cooler here and I feel much more sensitive to cold during the first hours dispite I have no more fevers (8-15 hours later) or diarrheas (3-7 hours later)since i stopped sugar.

That same thing happend to me, i did three big O's, and after every Big O my temprature went up and felt more sick but went a way after sleep. 
and then 2 days later i get the a flu without big O that last two days.   
This never happend during the summer i just got hot for mins and body temprature was back to normal.

i was scarred i thought got swine because i never get sick.   

Am in line with you here.
flu like symptoms
headaches
fatigue.
seems to lead to immune dysfuction.

so will it be the immune system is to strong or the immune system gets weaken after pois. or a totall different story.