[Defsync]

My OUT-OF-POIS test results. (Feeling well, 10 days after an N.E)

Serum Testosterone              27.6 nmol/L (8.0 - 30.0)
Serum Sex Hormone Binding Glob  52 nmol/L (13-71)
Serum TSH level                 1.2 miu/L (0.20-6.00)
Serum free T4 level            17.5 pmol/L (10.0-25.0)
Prostate Specific Antigen      1.00 ug/L (<3.00)
Serum FSH level                4.3 iu/L (1.0-9.0)
Serum prolactin level          149 mu/L (<550)

I have a question about TSH levels.
Is it better for it to be lower or higher?
In other words, does it go up with age or down?
Thanks everyone!

Thyroid Stimulating Hormone is the pituitary's reaction to how the Thyroid is performing. 1.2 is pretty much as normal as it gets. When yer thyroid is not producing enough, the TSH level shoots up as the pituitary tries to get the thyroid to up its production (indicative of hypothyroidism). When the TSH levels are lower ( < .8 ) it's the pituitary telling the thyroid to cool it (indicative of hyperthyroidism.)

[Defsync]

In regards to
Please consider this carefully.  A helpful response could save lives.

I was wondering if that statement might scare them off from even giving us a reply.
How about something like "would you be interested in working with us in the future or hearing more about this condition? etc etc"

Why would it scare someone off from replying?  If anything it would compel someone to reply, because there is a sense of urgency.  Mostly everyone is busy and no one particularly has time to spare if it doesn't seem urgent or especially fascinating. The honest answer (from most people) to the question you suggest would most likely be 'no'.  People need to realise this is both 1) urgent, 2) an opportunity to better understand fascinating connections between many areas of medicine (endocrinology, neurology, andrology, etc).

i still think a http link that includes "nakedscientist" is the most likely candidate for scaring someone off.

[horizon]

Limejuice,
did you ever get you SHBG level checked?

Does anyone know what the effects progesterone has on SHBG?
whether it traditionally is known to lower it or increase it?

Thanks

[demografx]

OK LET'S TRY THIS, I'M USING IT.

Dear Dr./Mr./Ms. X,

We would like to know if you would be interested in helping to research a serious new medical condition (described below). The smallest suggestion, idea, opinion or ideally a proposition from you to initiate some research, would be very welcome and appreciated. We already have a group of sufferers who would be willing to participate in a study.
 
The first cases were officially described in 2002, by Dr. Marcel Waldinger (MD PhD) and endocrinologist Dr. Dave Schweitzer, MD.(http://www.ncbi.nlm.nih.gov/pubmed/11995603).  He referred to the condition as "Postorgasmic Illness Syndrome" (POIS). His study results are attached.
 
Essentially, those with POIS usually suffer debilitating symptoms that follow within minutes of orgasm, and last for days. The symptoms include severe fatigue, anxiety, and cognitive impairment.
 
About 300 cases can be found directly (or are linked) on a POIS Science forum (see our link below), which is administered by a Cambridge physician.  Other cases are being increasingly described by the ISSM (International Society for Sexual Medicine).
 
Please consider this carefully.  A helpful reply means a great deal to us all. And If you have any questions, or need more information, please ask.

We look forward to working with you!
 
Best regards,
 
[Your username]
[or first name, surname initial - -
or full name if you're comfortable]
POIS Forum
h t t p : / / t i n y u r l . c o m / d 3 u v 8 8 [without spaces]


And please don't forget to add to Martin88's database:
http://pois.vndv.com/email_list.php

[demografx]

post-orgasm related studies
Stuart Brody of the University of Paisley, UK, and Tillmann Krüger of the Swiss Federal Institute of Technology in Zurich
http://www.newscientist.com/article/mg18925405.900

also Aliisa K. Humphries¹ and Jan Cioe¹
¹ Psychology Department, University of British Columbia Okanagan, Kelowna, BC
are doing/have done post-orgasm studies
http://www.sieccan.org/abstracts/vol18no3.html
http://web.ubc.ca/okanagan/psyo/faculty/cioe.html
(not exactly what we are looking for but there you go)

See we should be courting Canadian researchers! =D Canadians are very open minded people (in my experiences).

Great point, Defsync.! Now send 'em an email, I'm on the road!  []

[horizon]

http://en.wikipedia.org/wiki/Refractory_period_(sex)
According to some studies, 18-year-old males have a refractory period of about 15 minutes, while those in their 70s take about 20 hours, with the average for all men being about a half-hour.(5)

we should investigate who did the study on refractory periods for 70 year olds.
this is a great reason for a someone to study POIS in itself
references

Click on the wikipedia link above for the links in the references.
5.^ Kanner, Bernice. (2003). Are You Normal About Sex, Love, and Relationships? p. 52
Can someone find this book in their library/ or web? to find who did the study
(the author died in 2006 it seems)

further stuff from wikipedia:
http://en.wikipedia.org/wiki/La_petite_mort
2 studies in the references of La Petite Mort page:
http://www3.interscience.wiley.com/journal/118630802/abstract?CRETRY=1&SRETRY=0
E-mail: j.r.georgiadis@med.umcg.nl

http://www.springerlink.com/content/w580x14k0h15p38q/

[daveman]

I took some Claritin Clear, antihistamine yesterday, and man, I am never doing that again.  My POIS, as I've said before, comes in 2 stages, 1st is emotional (terrible mood, I want to kill somebody) , 2nd is mental (brain fog).  I haven't O'd in 15 days and took it on the 14th day.  Always as I "O", my brain fog stage turns into the emotional stage.  As I took the antihistamine, this had happened, very weird.  Thinking was crystal clear, but mood was the worst ever.
Testosterone, or should I say demografx  [)], I would try it, but I am a teenager with acne, and I think testosterone would probably be worse for me to take... right?  I believe I am full of it now.
Somebody else try claritin clear or an antihistamine (preferrably c.c. though) and see how they feel.

Hey GC,

Yeah, my trials with antihistamine (which compound is in Calritin Clear?) have been mixed at best. My emotional state is little effected by POIS, althugh I do get brain fog, so I haven't noticed any "depressive" effects. But I'd have to say that anti/histamines make it more worse than better.

On the other hand, I have found that noscapine ( in hot lemon cold/flu remedies ), especially on day 1 does wonders! I'd say that it does more than just help local symptoms, I'd have to say that it seems to reduce the length of the POIS session. Might be just a coincidence, but I 'O'd the night before last, took the cold remedy yesterday and today feel only about 5% POIS symptoms!! Go figure!

where do you get noscapine from i cant find it in stores and is it a cough suppresant.

I'm in Chile so things might be different. But here most hot cold/flue remedies have noscapine as the main ingredient. Is "Tapsin" a trademark there, I don't remember? I am Canadian, and it seems to me that when I lived there (16 yrs ago), cold remedies had like pseudo-ephidrine, among other things.

But yes, I understand that noscapine is a cough remedy, but seems to have a more general analgesic effect. Perhaps a residue of it's far opiate cousins.

But it seems more than a "pain killer". It's like it initiates some kind of change. And normally I usually only have to take it on day 1.

Formula, Tylonol 400mg, Noscapine 10mg, Cafiene 30mg.

By the way, Tylonol by itself doesn't do what the Noscapine does, there's a notable difference!

[daveman]

post-orgasm related studies
Stuart Brody of the University of Paisley, UK, and Tillmann Krüger of the Swiss Federal Institute of Technology in Zurich
http://www.newscientist.com/article/mg18925405.900

also Aliisa K. Humphries¹ and Jan Cioe¹
¹ Psychology Department, University of British Columbia Okanagan, Kelowna, BC
are doing/have done post-orgasm studies
http://www.sieccan.org/abstracts/vol18no3.html
http://web.ubc.ca/okanagan/psyo/faculty/cioe.html
(not exactly what we are looking for but there you go)

See we should be courting Canadian researchers! =D Canadians are very open minded people (in my experiences).

The Canadian health system lowers the significance of money as well. The whole issue of income is solved through the govt. plans. There are other countries that have similar systems.... perhaps they would be worth looking into as well. I'm not sure which they are though, but I think we're talking about Sweden, maybe Holland.... don't know, others?

[demografx]

Thanks, daveman, that's very helpful.

[nova]

My understanding from the information presented in this forum is that low levels of testosterone is only one of the reasons that one might experience POIS.  There have been a number of members on this forum that once they boosted their testosterone levels from a low level to a more medium one, benefited from a reduction of POIS symptoms. There is data out there that suggests that male average testosterone levels have decreased significantly over the past several decades. This information suggests firstly that POIS symptoms may be on the rise over the past 60 years, and secondly, that much more research should be done in zeroing in on the causes.  And have only testosterone levels been affected since the 1940's?  Have other hormone-levels been affected as well?

Below is the link as well as a quote from the link     


http://www.usdoctor.com/testone.htm [nofollow]
 The normal range of testosterone is reported as 350- 1200ng/dl. Studies in the 1940's showed the average testosterone level to be at 700 ng/dl, 300 ng/dl higher than for men today. In the past, a drop in testosterone levels to 250 ng/dl was rarely reported before men were 80 years of age. Yet today, it is not an uncommon value for middle aged men!

[daveman]

It's great that exercise works for you guys and it reduces the days of the pois.
When I was having pois it was so severe that there was no energy for exercise, and if I tried I would risk cardiac attack or complete shutdown. I once tried going out for a run, and nearly collapsed. For me the best thing was just to sleep and recover gently.
Now that I'm strong enough and don't get pois anymore, I can exercise again, and love a good workout. The key, like you said is not to over-exert yourself.

That's my case as well. Don't dare even try. There's an overpass on the highway that I have to cross (with about 2 stories of stairs). When I'm in day 1 my heart just about comes out of my chest when I cross it. On a normal day, no problem, don't even breath hard!

[nova]

Following is a list of some scientific studies about the importance of proper testosterone levels: 

Low testosterone linked to long-term risk of death in relatively healthy adult men
ENDO 2007: The Endocrine Society Research Summaries Book June 5, 2007 (The group with low testosterone levels had a 33 percent greater risk of death during the next 18 years than the men with higher testosterone.)

1. Bringing testosterone from low normal to high normal lowers the risk for heart disease by 60%
The Journal of Clinical Endocrinology & Metabolism. Aug 2002. Vol. 87, No. 8 3632-3639
2. 2 year study of low dose testosterone on libido in men
Clin Endocrinol Metab 1997
3. Dihydrotestoerone reduces prostate size
Ann Med 1993 Jun;25(3):235-41
4. Testosterone Improves Sexual Function, Mood, Muscle Strength, and Body Composition Parameters in Hypogonadal Men Improved:
J Clin Endocrinol Metab 85: 2839-2853, 2000
* Sexual function
* mood
* muscle strength, leg > arm
* Subjects did not exercise
* Improved lean body mass and fat mass
* Correlated with serum level of T obtained
Study showed that these benefits were not obtained with testosterone patches (Testosterone patches are too weak for most patients)
5. Testosterone supplementation increased working memory in men.
Janowsky J et al. Sex steroids modify working memory. J Cogn Neurosci 2000 May;12(3):407-14
6. Testosterone replacement reduces the risk of Alzheimer’s disease by preventing the production of beta amyloid precursor protein.
Gouras GK et al. Proc Natl Acad Sci U S A 2000 Feb 1;97(3):1202-5
7. Testosterone levels correlates with and testosterone replacement improves cognitive function.
Hormones and Behavior 1998; 33(2):85-94.
J Clin Endocrinol Metab 1999 Oct;84(10):3681-5
8. Testosterone replacement is more effective than antidepressants for depression.
Am J Psychiatry 157:1884, November 2000
Androl 1992 Jul-Aug;13(4):297-304
9. Low testosterone associated with fatigue and testosterone replacement increases sense of well being.
Many patients are able to stop Antidepressants after being treated with testosterone
Geriatr Psychiatry Neurol 2000 Summer;13(2):93-101
10. The lower the active testosterone the higher the risk for heart attack.
Circulation 1999 Apr 6;99(13):1666-70
- Acute anti-ischemic effect of testosterone in men with coronary artery disease
- Testosterone improves exercise induced ST depression
- Dilates coronary arteries
“Short-term administration of testosterone induces a beneficial effect on exercise- induced myocardial ischemia in men with coronary artery disease. This effect may be related to a direct coronary-relaxing effect.”
11. Men with heart disease have significantly lower:
- Total testosterone
- Free testosterone
- Bioavailability testosterone
-Men with coronary artery disease have lower levels of androgens than men with normal coronary angiograms.
Eur Heart J 2000 Jun;21(11):890-4
12. Low testosterone increases the risk of heart disease and more optimal levels decrease the risk of heart disease.
Int J Obes Relat Metab Disord, July 2003
13. Low testosterone levels increase the risk of prostate cancer and testosterone replacement expected to reduce risk of prostate cancer.
Dihydrotestosterone and testosterone levels in men screened for prostate cancer: a study of a randomized population.Br J Urol 1996 Mar;77(3):433-40
- DHT is lower in prostate cancer patients
- DHT is lower in more advanced tumors
- PSA and DHT have an inverse relationship (high DHT lower PSA)
14. Testosterone replacement is better than exercise to reduce body fat, gain lean muscle and improve strength, and works synergistic with exercise.
J Endocrinol 2001 Jul;170(1):27-38
15. Testosterone replacement reduces risk of diabetes.
- Testosterone replacement decreases insulin resistance
- Low levels of testosterone play a role in the development of type 2 diabetes
- Elevated insulin decreases testosterone levels resulting in a vicious cycle of worsening insulin resistance and reduced testosterone levels
- Testosterone replacement breaks this cycle
- Low testosterone is associated with Syndrome X, hypertension, type 2 diabetes and heart disease.
Journal of American Epidemiology 1996
Int J Obes Relat Metab Disord 2000
Mayo Clin Proc 2000 Jan;75 Suppl:S61-4
Diabetes Care. 2000 Apr;23(4):490-4
Metabolism 1997 May;46(5):526-9
16. Dihydrotestoterone with NSAIDS kills prostate cancer cells.
Cancer Chemother Pharmacol, 2002; 49(3):179-86
17. Using HCG to boost testosterone levels results in significant improvement in prostate enlargement and symptoms
Journal of Urology 2003
18. Testosterone replacement decreases fat and increases lean muscle.
Bhasin et al. journal of Endocrinology and Metabolism, 2003
19. Testosterone replacement speeds healing and results in the shortening of hospital stays.
Journal Am Geriatr Soc, 2002
20. Pesticides reduce testosterone production in men.
Biology and Reproduction, 2003
 

[nova]

When one reviews my two previous posts (average testosterone levels in males have significantly dropped during the past 60 years, and that testosterone is important for general health, one might be surprised that there has not been a bigger ruckus both in the medical profession and the media about the problem.  This forum has made strides in coming up with a solution to POIS, including inquiries to various medical practitioners.  Although low testosterone levels are not the only cause of POIS, I feel that an enterprising media reporter might find it helpful to his or her career to break a major story.  I'm trying to be objective when I say that it would not surprise me to find the following story as the cover article of Time or Newsweek: A New Outlook on Testosterone: Are Men's Health in Danger?  I am shocked that the fact that testosterone levels in males is much lower than 60 years ago has not garnered more attention, considering the importance testosterone for men's health.  Possibly one of the reasons for the lack of interest is the fact that many might be turned off by the fact that some athlete's are misusing testosterone treatment (steroids) and thus the treatment has gotten a negative spin.  Due to the negative connotations of the word testosterone/steroids, a media story on the subject would have to be very well done and balanced.

[demografx]

Following is a list of some scientific studies about the importance of proper testosterone levels: 

Low testosterone linked to long-term risk of death in relatively healthy adult men
ENDO 2007: The Endocrine Society Research Summaries Book June 5, 2007 (The group with low testosterone levels had a 33 percent greater risk of death during the next 18 years than the men with higher testosterone.)

1. Bringing testosterone from low normal to high normal lowers the risk for heart disease by 60%
The Journal of Clinical Endocrinology & Metabolism. Aug 2002. Vol. 87, No. 8 3632-3639
2. 2 year study of low dose testosterone on libido in men
Clin Endocrinol Metab 1997
3. Dihydrotestoerone reduces prostate size
Ann Med 1993 Jun;25(3):235-41
4. Testosterone Improves Sexual Function, Mood, Muscle Strength, and Body Composition Parameters in Hypogonadal Men Improved:
J Clin Endocrinol Metab 85: 2839-2853, 2000
* Sexual function
* mood
* muscle strength, leg > arm
* Subjects did not exercise
* Improved lean body mass and fat mass
* Correlated with serum level of T obtained
Study showed that these benefits were not obtained with testosterone patches (Testosterone patches are too weak for most patients)
5. Testosterone supplementation increased working memory in men.
Janowsky J et al. Sex steroids modify working memory. J Cogn Neurosci 2000 May;12(3):407-14
6. Testosterone replacement reduces the risk of Alzheimer’s disease by preventing the production of beta amyloid precursor protein.
Gouras GK et al. Proc Natl Acad Sci U S A 2000 Feb 1;97(3):1202-5
7. Testosterone levels correlates with and testosterone replacement improves cognitive function.
Hormones and Behavior 1998; 33(2):85-94.
J Clin Endocrinol Metab 1999 Oct;84(10):3681-5
8. Testosterone replacement is more effective than antidepressants for depression.
Am J Psychiatry 157:1884, November 2000
Androl 1992 Jul-Aug;13(4):297-304
9. Low testosterone associated with fatigue and testosterone replacement increases sense of well being.
Many patients are able to stop Antidepressants after being treated with testosterone
Geriatr Psychiatry Neurol 2000 Summer;13(2):93-101
10. The lower the active testosterone the higher the risk for heart attack.
Circulation 1999 Apr 6;99(13):1666-70
- Acute anti-ischemic effect of testosterone in men with coronary artery disease
- Testosterone improves exercise induced ST depression
- Dilates coronary arteries
“Short-term administration of testosterone induces a beneficial effect on exercise- induced myocardial ischemia in men with coronary artery disease. This effect may be related to a direct coronary-relaxing effect.”
11. Men with heart disease have significantly lower:
- Total testosterone
- Free testosterone
- Bioavailability testosterone
-Men with coronary artery disease have lower levels of androgens than men with normal coronary angiograms.
Eur Heart J 2000 Jun;21(11):890-4
12. Low testosterone increases the risk of heart disease and more optimal levels decrease the risk of heart disease.
Int J Obes Relat Metab Disord, July 2003
13. Low testosterone levels increase the risk of prostate cancer and testosterone replacement expected to reduce risk of prostate cancer.
Dihydrotestosterone and testosterone levels in men screened for prostate cancer: a study of a randomized population.Br J Urol 1996 Mar;77(3):433-40
- DHT is lower in prostate cancer patients
- DHT is lower in more advanced tumors
- PSA and DHT have an inverse relationship (high DHT lower PSA)
14. Testosterone replacement is better than exercise to reduce body fat, gain lean muscle and improve strength, and works synergistic with exercise.
J Endocrinol 2001 Jul;170(1):27-38
15. Testosterone replacement reduces risk of diabetes.
- Testosterone replacement decreases insulin resistance
- Low levels of testosterone play a role in the development of type 2 diabetes
- Elevated insulin decreases testosterone levels resulting in a vicious cycle of worsening insulin resistance and reduced testosterone levels
- Testosterone replacement breaks this cycle
- Low testosterone is associated with Syndrome X, hypertension, type 2 diabetes and heart disease.
Journal of American Epidemiology 1996
Int J Obes Relat Metab Disord 2000
Mayo Clin Proc 2000 Jan;75 Suppl:S61-4
Diabetes Care. 2000 Apr;23(4):490-4
Metabolism 1997 May;46(5):526-9
16. Dihydrotestoterone with NSAIDS kills prostate cancer cells.
Cancer Chemother Pharmacol, 2002; 49(3):179-86
17. Using HCG to boost testosterone levels results in significant improvement in prostate enlargement and symptoms
Journal of Urology 2003
18. Testosterone replacement decreases fat and increases lean muscle.
Bhasin et al. journal of Endocrinology and Metabolism, 2003
19. Testosterone replacement speeds healing and results in the shortening of hospital stays.
Journal Am Geriatr Soc, 2002
20. Pesticides reduce testosterone production in men.
Biology and Reproduction, 2003
 

I can certainly attest to many of the positive effects listed above since starting TRT (testosterone replacement therapy) two years ago.

[Animus]

I'm traveling for a few more days, it's clumsy to send/file correspondence on iPhone. Anyone care to send an email to horizon's contacts? (2nd post above). Thanks!!

http://en.wikipedia.org/wiki/Refractory_period_(sex)
According to some studies, 18-year-old males have a refractory period of about 15 minutes, while those in their 70s take about 20 hours, with the average for all men being about a half-hour.(5)

we should investigate who did the study on refractory periods for 70 year olds.
this is a great reason for a someone to study POIS in itself
references

Click on the wikipedia link above for the links in the references.
5.^ Kanner, Bernice. (2003). Are You Normal About Sex, Love, and Relationships? p. 52
Can someone find this book in their library/ or web? to find who did the study
(the author died in 2006 it seems)

further stuff from wikipedia:
http://en.wikipedia.org/wiki/La_petite_mort
2 studies in the references of La Petite Mort page:
http://www3.interscience.wiley.com/journal/118630802/abstract?CRETRY=1&SRETRY=0
E-mail: j.r.georgiadis@med.umcg.nl

http://www.springerlink.com/content/w580x14k0h15p38q/

That sounds like a really great idea to me- linking refractory periods and POIS. Keep up the good work...

[Animus]

When one reviews my two previous posts (average testosterone levels in males have significantly dropped during the past 60 years, and that testosterone is important for general health, one might be surprised that there has not been a bigger ruckus both in the medical profession and the media about the problem.  This forum has made strides in coming up with a solution to POIS, including inquiries to various medical practitioners.  Although low testosterone levels are not the only cause of POIS, I feel that an enterprising media reporter might find it helpful to his or her career to break a major story.  I'm trying to be objective when I say that it would not surprise me to find the following story as the cover article of Time or Newsweek: A New Outlook on Testosterone: Are Men's Health in Danger?  I am shocked that the fact that testosterone levels in males is much lower than 60 years ago has not garnered more attention, considering the importance testosterone for men's health.  Possibly one of the reasons for the lack of interest is the fact that many might be turned off by the fact that some athlete's are misusing testosterone treatment (steroids) and thus the treatment has gotten a negative spin.  Due to the negative connotations of the word testosterone/steroids, a media story on the subject would have to be very well done and balanced.

Wow, that's a very interesting fact...you bring up. Yes, you think there would be more attention put to something like this. I wonder about it, and I'll ask my doctor next time I see him.

[Animus]

I'm traveling for a few more days, it's clumsy to send/file correspondence on iPhone. Anyone care to send an email to horizon's contacts? (2nd post above). Thanks!!

Yes, I'll look into contacting them based on the info H posted...thanks.  Good luck on your trip...

[Animus]

why does it take around 7 days to recover from POIS?

My theory - but far from fact - is that very slow sperm regeneration time (SRT) causes the long recovery.

Since TRT, my SRT is now very quick, and POIS is vastly reduced. When I'm "full" (again), I'm fine.

Anyone agree/disagree?

I agree... I think it has to do with sperm and semen regeneration too. I was looking up the time it takes to make sperm, and found that it takes about 74 days, and is being done all the time, but it takes 2-6 days for the sperm to make their final journey and mature fully... the article is here:  http://www.ehow.com/about_5503589_long-sperm-mature.html

So I found that interesting because it seems to match the time it takes to recover...

i disagree... i can get POIS symptoms without ejaculating sperm, simply from the "feel good" contraction one gets during orgasm. A person familiar with kama sutra and tantric sex practices knows how to do this. I just learned it when I was a kid "experimenting".

This is why i believe POIS (at least mine) has to do with the histamine released from the mast cells in the genitalia. my theory is that for w/e reason my brain is unable to break it down properly and in a timely manner, and it causes my POIS (which is mainly mental dysfunction 3-5 days.)

Interesting.

[Animus]

Here's a letter I sent before you posted the inquiry letter, demo. Yours is a little more to the point. But I thought I'd post this anyway. I'll keep working on this.

Greetings Dr.Munarriz,
(Personal greeting...variable)I write to you as a member of a growing forum of men who experience something called "Post Orgasmic Illness Syndrome." The term was coined by Dr. M.D Waldinger in a 2002 paper in the Journal of Sex & Marital Therapy, in which he described two cases of this illness.

We are a forum of more than 300; 95% being men. The forum was started in England, in 2007, on a science discussion website, and has now members throughout the world,  of varying ages and backgrounds. The site is moderated, and we are part support- group, part compendium of data, and part laboratory.  Our members have created a survey, an excellent video describing the illness, a website, and other resources.

The forum itself is over 300 pages long and has many committed members. What we have in common is that we experience similar serious physical and mental adverse symptoms after ejaculation which last between 4 and 7 days. We are trying to investigate and overcome this and find that we are often outside the parameters of known medicine. Many of us have tried therapies based on science, intuition, and theory, with varying degrees of success. But as of yet, we have not gained the kind of medical scrutiny and cure that we are seeking.

In the very least we would like to get on your "radar" as an illness that has yet to be studied more extensively. Our goal is to enter into a study which will start to investigate POIS. The phenomenon of POIS is predictable, repeatable, and the symptoms are shared by many. We feel there may be many more like us who suffer this illness with no clear diagnosis or cure.

We feel the next step is to share our data with a medical researcher, who can do an objective, detailed investigation. Here is a link to our site: http://sites.google.com/site/poiswebsite/home

Please let me know if the BU School of Sexual Medicine has any resources which could help us or interest in this matter. Thank you.

Sincerely,
X
(then I included my contact info.)

[EDS]

daveman, you said you had a vasectomy reversal and pois started after that. have you tried having your reversal reversed to see if that doesnt take care of the problem.


is there anybody here who has a vasectomy and has pois?

Sorry for replying so late but I am trying to catch up with the forum after being away for a while.

Yes I have had a vasectomy - thinking it might help POIS symptoms - but it did not  [:-'(]. I had the surgery about 10 years ago and the only thing I have found that helps since then is testosterone patches, thanks to Demo.

I think that was another question a few pages back.... "Has anyone else benefited from testosterone treatment?" I can be placed in that category  []. I use 5mg patches and it has helped me greatly by reducing the symptoms and length of time that symptoms are present.

I will catch up to current posts and input anything that may be helpful.