[Green]

I'm also having severe problems with sport in POIS, with only 1-2 hours exercise each week since last November : increased difficulty to work in the following days, exhaustion, joint pain.
I just don't know what to do with that. I can stop but I think I need it for cardiovascular health so I don't (an other good reason for scientists to research about POIS!).
I must say that I have to stand up for a long time in my work and this doesn't help.

For a number of years I've been taking Diclofenac Sodium 50mg X3 a day for two weeks subsequent to orgasm, it helps a lot more than Paracetamol/cocadmol. I can't take Ibuprofen for prolonged periods of time as it worsens my already quite severe acid reflux problems.

Unlike some of the other medicines and herbs which have a limited effect in lessening POIS symptoms, this has consistently provided me with relief over the years.

In the Ashby POIS article, where the patient was given the same medication and saw a markedly reduced POIS episode, this is not long lived and the effect of the medication will reduce over time and useage. I would only rate the effectiveness of taking Diclofenac in relation to the feeling out of POIS to be <20% at the most, which is still quite significant.

This begs the question what mechanism is in play when we get POIS that an anti-inflammatary medicines respond well? (in my case anyways)

[Green]

Even if I wasn't tested for vitamin D I think I can have it too low.

I don't recall seeing it, how do we get tested for Vitamin D? Bloodtest with standard doctor's lab tests?

Yep just via a serum sample of blood, it should really be included in routine blood tests, but I guess that varies from doctor to doctor.

[Vandemolen3]

Demo, maybe it's an idea to send a pm to all the members of the POIS-forum. And to ask if they had a blood test for Vitamin D. And if not, maybe they can ask their doctor. Of almost 10 members it's know that they have a low Vitamin D. After your mail maybe it will occur that 50 or more members have a low Vitamin D. With this knowledge we can contact a doctor like dr. Dexter.

P.S. Maybe we can make list for Vitamine D, like B_Jim did in general.

[Counterpoints]

Demo, maybe it's an idea to send a pm to all the members of the POIS-forum. And to ask if they had a blood test for Vitamin D. And if not, maybe they can ask their doctor. Of almost 10 members it's know that they have a low Vitamin D. After your mail maybe it will occur that 50 or more members have a low Vitamin D. With this knowledge we can contact a doctor like dr. Dexter.

P.S. Maybe we can make list for Vitamine D, like B_Jim did in general.

It would be very hard to go through and compile a list of everyone to PM.  Even if we used a computer script to do this, it would be a lot of work to then go and PM all of these people, because you can only send messages to up to five people at a time.

Also, is the evidence really that strong?  More so than for testosterone deficiency, or cortisol excess, or pituitary abnormalities?  If we took a random sample of the population we would also find people low on vitamin D -- is the proportion here significantly more than that?

It's an interesting idea, but a mass PM should probably be reserved for when we have more evidence. 

[GoingCrazy]

Has anyone been completely celibate for one cycle?  (From day 0, all the way up to an NE)  By completely celibate, i mean, not touching or stimulating yourself what so ever.  I think that sexual stimulation is part of POIS, It releases serotonin and other chemicals.  It stimulates these certain nervous functions, and orgasm is just a big blast of stimulation.  I still seem to get bits of POIS if I am even slightly stimulated, orgasm is the worst I could do.

Maybe we do have a simple chemical imbalance that can be overcome by quality sleep (sleep between 9-10, wake between 8-10) diet, and possibly exercise... just if we resist stimulation...

[Counterpoints]

I've said this before, but my POIS feels a lot like an addiction.  Sometimes I have one orgasm, and I desperately crave another.  Then with the next, the craving may go away, and I may even feel euphoric for a time, but I eventually develop HUGE withdrawal symptoms after two days.  These are immediately alleviated by yet another orgasm.  But at this point I've developed brain fog and other symptoms.

[demografx]

Demo, maybe it's an idea to send a pm to all the members of the POIS-forum. And to ask if they had a blood test for Vitamin D...

If we took a random sample of the population we would also find people low on vitamin D -- is the proportion here significantly more than that?

(Following is linked:)

Vitamin D deficiency is widespread among U.S. population, expectant mothers are deficient and giving birth to deficient infants

[Vandemolen3]

Demo, maybe it's an idea to send a pm to all the members of the POIS-forum. And to ask if they had a blood test for Vitamin D. And if not, maybe they can ask their doctor. Of almost 10 members it's know that they have a low Vitamin D. After your mail maybe it will occur that 50 or more members have a low Vitamin D. With this knowledge we can contact a doctor like dr. Dexter.

P.S. Maybe we can make list for Vitamine D, like B_Jim did in general.

It would be very hard to go through and compile a list of everyone to PM.  Even if we used a computer script to do this, it would be a lot of work to then go and PM all of these people, because you can only send messages to up to five people at a time.

Also, is the evidence really that strong?  More so than for testosterone deficiency, or cortisol excess, or pituitary abnormalities?  If we took a random sample of the population we would also find people low on vitamin D -- is the proportion here significantly more than that?

It's an interesting idea, but a mass PM should probably be reserved for when we have more evidence. 

You are right. A lot of people have low Vitamin D.

But it should be better that more members of the POIS-forum had a bloodtest for hormons and vitamins.

[Vandemolen3]

Has anyone been completely celibate for one cycle?  (From day 0, all the way up to an NE)  By completely celibate, i mean, not touching or stimulating yourself what so ever.  I think that sexual stimulation is part of POIS, It releases serotonin and other chemicals.  It stimulates these certain nervous functions, and orgasm is just a big blast of stimulation.  I still seem to get bits of POIS if I am even slightly stimulated, orgasm is the worst I could do.

Maybe we do have a simple chemical imbalance that can be overcome by quality sleep (sleep between 9-10, wake between 8-10) diet, and possibly exercise... just if we resist stimulation...

I am 'clean' for more than two weeks. I will try to avoid an O or other things for another three weeks. I want to check how I react on a few weeks of Thyrax and Vitamin D supplement.

[demografx]

I think that sexual stimulation is part of POIS

Several people have also reported that, but stimulation has absolutely no effect on me personally. In fact, it sometimes even strengthens well-being if it doesn't go any further. I've also seen that reported in a number of writings.

Yet another baffling, elusive idea for POIS  []

[demografx]

Even if I wasn't tested for vitamin D I think I can have it too low.

I don't recall seeing it, how do we get tested for Vitamin D? Bloodtest with standard doctor's lab tests?

Yep just via a serum sample of blood, it should really be included in routine blood tests, but I guess that varies from doctor to doctor.

Thanks, green!

[GoingCrazy]

I think that sexual stimulation is part of POIS

Several people have also reported that, but stimulation has absolutely no effect on me personally. In fact, it sometimes even strengthens well-being if it doesn't go any further. I've also seen that reported in a number of writings.

Yet another baffling, elusive idea for POIS  []

The stimulation pois thing is different for me and took some time to notice.  It's like how normal POIS symptoms appear mainly the day after O'ing.  Just simple stimulation for me takes its toll, but not right after, maybe a couple hours after I will develop brain fog or be in a weird mood.

[GoingCrazy]

Has anyone been completely celibate for one cycle?  (From day 0, all the way up to an NE)  By completely celibate, i mean, not touching or stimulating yourself what so ever.  I think that sexual stimulation is part of POIS, It releases serotonin and other chemicals.  It stimulates these certain nervous functions, and orgasm is just a big blast of stimulation.  I still seem to get bits of POIS if I am even slightly stimulated, orgasm is the worst I could do.

Maybe we do have a simple chemical imbalance that can be overcome by quality sleep (sleep between 9-10, wake between 8-10) diet, and possibly exercise... just if we resist stimulation...

I am 'clean' for more than two weeks. I will try to avoid an O or other things for another three weeks. I want to check how I react on a few weeks of Thyrax and Vitamin D supplement.

You are 100% clean?  Not even touching?  That seems like you would have to put in a lot of effort to do that.

[GoingCrazy]

I've said this before, but my POIS feels a lot like an addiction.  Sometimes I have one orgasm, and I desperately crave another.  Then with the next, the craving may go away, and I may even feel euphoric for a time, but I eventually develop HUGE withdrawal symptoms after two days.  These are immediately alleviated by yet another orgasm.  But at this point I've developed brain fog and other symptoms.

Same as with me, after the first on I say "what the heck," than just do it without thinking.

[martin88]

after checking I changed my last post: I took L-carnitine instead of acetyl-L-carnitine.

Eventually vitamin D deficiency is a symptom of POIS and not a cause (link with endocrine gland parathyroid?)

I don't think so. My low Vitamin D is caused by a lack of sun. And I don't use milkproducts, sometime a little bit of cheese.

Low vitamin D can also be a symptom if POIS sufferers are staying more indoor because of all the other symptoms. I agree it should be tested for everyone.

For a number of years I've been taking Diclofenac Sodium 50mg X3 a day for two weeks subsequent to orgasm, it helps a lot more than Paracetamol/cocadmol. I can't take Ibuprofen for prolonged periods of time as it worsens my already quite severe acid reflux problems.

Unlike some of the other medicines and herbs which have a limited effect in lessening POIS symptoms, this has consistently provided me with relief over the years.

In the Ashby POIS article, where the patient was given the same medication and saw a markedly reduced POIS episode, this is not long lived and the effect of the medication will reduce over time and useage. I would only rate the effectiveness of taking Diclofenac in relation to the feeling out of POIS to be <20% at the most, which is still quite significant.

This begs the question what mechanism is in play when we get POIS that an anti-inflammatary medicines respond well? (in my case anyways)

Perhaps Dr Waldinger's study will help to answer. Was this treatment effective also for fatigue?

Several people have also reported that, but stimulation has absolutely no effect on me personally.

Me too but this could be different when I was between 20-30yo (however always very mild symptoms and short lasting).
 

[Counterpoints]

I think that sexual stimulation is part of POIS

Several people have also reported that, but stimulation has absolutely no effect on me personally.

I think that sexual stimulation is part of POIS

Several people have also reported that, but stimulation has absolutely no effect on me personally.

Same with me.  However, looking at pornography can make things worse.  Also, if I get really close to orgasm, I often can't just stop everything and go back to normal.  I'll feel quite tense.  I don't think this is specific to POIS, I think this is normal.  This makes me think it would be hard to follow Marnia's (sex without orgasm) suggestions.

[Vandemolen3]

Low vitamin D can also be a symptom if POIS sufferers are staying more indoor because of all the other symptoms. I agree it should be tested for everyone.

That's possible. The day after an O if it is possible I stay the whole day at home on the couch.

[Vandemolen3]

You are 100% clean?  Not even touching?  That seems like you would have to put in a lot of effort to do that.

I am single at the moment. So it's so hard.

But today I had POIS like symptoms: thick eyelids, moist eyes, feeling sick, joints en muscles hurt, my back hurts, feeling cold and tired. And all that because I feel asleep on the couch.

Maybe POIS has to do something with the muscles and joints. We are sexually so tense that after an O the body can't have a good realease. And then everything blocks. And then the body thinks you are sick and makes somes antibodies.
I found out that stimulation under the shower brings less POIS-symptoms than on other place. That's because under the shower you are more relaxed. The joints and muscles are more relaxed.

[Vandemolen3]

I think that sexual stimulation is part of POIS

Several people have also reported that, but stimulation has absolutely no effect on me personally. In fact, it sometimes even strengthens well-being if it doesn't go any further. I've also seen that reported in a number of writings.

Yet another baffling, elusive idea for POIS  []

Lucky you. I thought that POIS came only after an O. But with stimulation I've POIS-symptoms too. Not so bad after an O. The symptoms are small and after 1 day I feel 100 %.

[horizon]

Horizon how many hrs did use it before orgasm.

it was 5 days after I took it (Norethisterone) 4x5mg.
On a second occasion I took 2x5mg about 24hrs after. no positive effects.

Ive yet to try it prior to orgasm,
but Im thinking its not for me.