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  4. Post Orgasmic Illness Syndrome (POIS)
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Post Orgasmic Illness Syndrome (POIS)

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Offline strike333

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8860 on: 17/08/2010 01:23:43 »
what other hormones should be tested, other than testosterone, progesterone and prolactin?
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8861 on: 17/08/2010 02:10:31 »
Quote from: strike333 on 17/08/2010 01:23:43
what other hormones should be tested, other than testosterone, progesterone and prolactin?
Neurotransmitters like dopamin and serotonin?
And Ts4 (thyroid).
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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8862 on: 17/08/2010 03:37:11 »
Quote from: RhythmSpring on 16/08/2010 20:48:52
And how did that work for you? I'm sorry, I don't feel like sifting back through this mess of a thread.

If this forum is such a mess why dont you leave and make all that progress you can make with your most organized existence.
If you were anttentive enough you would know how to look for counterpoint's old post without looking through all pages and you would also know what is needed to know is on the pois website.

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8863 on: 17/08/2010 03:48:52 »
Quote from: RhythmSpring on 16/08/2010 20:14:14
I went to the pharmacy inquiring about progesterone cream, and they said, "well THIS is like progesterone in that it gets converted into it when it's ingested," and they showed me a container of Plan B emergency contraceptive for women.

Yes? No? Bad idea? Good idea?

if this mess of a forum didnt exist you would have all the world to answer all the most fantastic questions you have.

plan b contains levornorgestrel a form of progesterone.
It is has about 5.3 the progesterone effect of noriethisterone and 8 times the testosterone effect of noriethisterone.
instead of buying plan b buy next choice it is much cheaper and if you have a kroger pharmacy or ralph they sell it much cheaper than others.

If there is no way to get noriethisterone it is the only option you have if you are willing to try progesterone.

I have tried it and i am 60% sure it will work, i itend on trying again soon.
I had another orgasm immedieatly after what i believe to a great first try without taking  another dose of levonorgestrel, and resulted in very strong pois.
I will advise one orgasm per dose to get best result.

* Any drug used should be under supervision of your doctor.*
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Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8864 on: 17/08/2010 15:56:32 »
Quote from: RhythmSpring on 16/08/2010 20:48:52
And how did that work for you? I'm sorry, I don't feel like sifting back through this mess of a thread.

You can search through the thread with google.  The norethisterone didn't work for me.  In answer to your first question, my instinct is to try something stronger at first (like an oral tablet of norethisterone instead of a progesterone cream), and if it works, regulate to find the appropriate dose -- especially since in the article Dr. Dexter said that the cream didn't work but the pills did.  Of course, I am not making any official recommendation, and I suggest consulting with a doctor.
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Offline strike333

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8865 on: 17/08/2010 17:52:55 »
my family doctor is on vacation right now, I have to wait a week to get results for my hormone test.  I'm wondering if I go to the emergency hospital and ask for a hormone test, would they get it for me right away?
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Offline GreenWyvern

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8866 on: 17/08/2010 19:25:27 »
I have been suffering from POIS for many years, but I've recently experienced a significant alleviation of symptoms after taking 500mg/day of L-Carnitine for a few weeks. I'm certain the effect was due to this supplement, as I was doing nothing else different.

Has anyone else had good results with L-Carnitine?
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Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8867 on: 17/08/2010 19:56:18 »
Quote from: GreenWyvern on 17/08/2010 19:25:27
I have been suffering from POIS for many years, but I've recently experienced a significant alleviation of symptoms after taking 500mg/day of L-Carnitine for a few weeks. I'm certain the effect was due to this supplement, as I was doing nothing else different.

Has anyone else had good results with L-Carnitine?

Interesting.  What were your symptoms, specifically?
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Offline Green

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8868 on: 17/08/2010 20:54:47 »
Quote from: strike333 on 17/08/2010 17:52:55
my family doctor is on vacation right now, I have to wait a week to get results for my hormone test.  I'm wondering if I go to the emergency hospital and ask for a hormone test, would they get it for me right away?

Depends where you are I suppose, I doubt you'll get the desired blood tests by turning up to A&E but it might prompt your GP to investigate thoroughly.

If the POIS or symptoms you are facing severe, do get it checked out! Just be careful the way you ascribe to your symptoms as otherwise you'll get pushed down the mental health route like me, it did me no favours.
« Last Edit: 17/08/2010 21:27:38 by green »
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Offline GreenWyvern

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8869 on: 17/08/2010 21:15:52 »
Quote from: Counterpoints on 17/08/2010 19:56:18
Quote from: GreenWyvern on 17/08/2010 19:25:27
I have been suffering from POIS for many years, but I've recently experienced a significant alleviation of symptoms after taking 500mg/day of L-Carnitine for a few weeks. I'm certain the effect was due to this supplement, as I was doing nothing else different.

Has anyone else had good results with L-Carnitine?

Interesting.  What were your symptoms, specifically?

Fairly standard: wiped out, fuzzy thinking, anger alternating with depression, difficulty speaking/remembering words, insomnia, often pain in heart area, tension in neck, headaches. Worse on second day, took 10-14 days to disappear.
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8870 on: 18/08/2010 01:34:13 »
GreenWyvern, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:


Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

Filling out the POIS survey created by "Counterpoints" can help you to share more POIS information and details with others here, as well as with future outside researchers.
http://pois.olympe-network.com/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
http://forums.delphiforums.com/POIS/chat

First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

  
Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


There are a couple of ways to get any or all of the above 3 studies: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF.

Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 3 years, our POIS forum has attracted over 150 POIS sufferers worldwide who have posted here, plus over 700,000 page visits. Not bad for a rare malady!

« Last Edit: 18/08/2010 02:31:52 by demografx »
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8871 on: 18/08/2010 01:38:02 »

GreenWyvern, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: 3 years' worth of posts (nearly 9,000 posts!) from 150+ Forum members, and an additional 150 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
demografx POIS site:http://thenakedscientists.com/

and 1,000+ results came up for "demografx" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8872 on: 18/08/2010 01:44:29 »
Quote from: GreenWyvern on 17/08/2010 19:25:27

Has anyone else had good results with L-Carnitine?


GreenWyvern, You can see the several discussions here that have included L-Carnitine:
http://www.google.com/#hl=en&source=hp&q=+L-Carnitine+POIS+site%3Ahttp%3A%2F%2Fthenakedscientists.com&rlz=1W1DAUS_en&aq=f&aqi=&aql=&oq=&gs_rfai=&pbx=1&fp=14dfc091e20a8b56
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8873 on: 18/08/2010 02:23:18 »
Quote from: strike333 on 17/08/2010 01:23:43

what other hormones should be tested, other than testosterone, progesterone and prolactin?


strike333, there is no single universally-agreed-upon hormone test here at the forum. Take a look at what some of the longer-term forum members - as well as some of the newer members - have tested. Here's mine, just as an EXAMPLE, taken from an old post. I was very lucky in that testosterone deficiency was a major finding for my POIS. I have been on TRT (replacement therapy) and it has helped my POIS enormously (but that doesn't mean it will necessarily help yours):

MY ENDOCRINOLOGIST'S LABWORK ORDERED FOR POIS

-PROLACTIN

-TESTOSTERONE

   -Bioavailable Testosterone,
   -Free Testosterone,
   -Total Testosterone,
   -Sex Hormone Globulin Binding (SHGB)

-DHEA-SULFATE

-FSH (Follicle Stimulating Hormone)

-LH (Luteinizing Hormone)

-TSH (Thyroid-Stimulating Hormone)

-CORTISOL

Hope this helps.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8874 on: 18/08/2010 15:30:54 »
Result of blood tests:

TSH           mU/L           4.3 (was 4.7)
Free T4       pmol/l         11 (was 12)
Testosterone  nmol/L         11
Prolactin     U/l            0.17
Progesterone  nmol/l         1.4

Hemoglobin    nmol/l         8.9
Hermatocriet  rel.fract      0.42
MCV           fl               84
MCH           fmol           1.78
erythrocytes  10e12/l        5.00
platelets     10e9/l         184
leukocytes    10e9/l         6.1
Neutrophils   10e9/l         4.1
Lymphocytes   10e9/l         1.6
Monocytes     10e9/l         0.3
Eosinophils   10e9/l         0.1
Basophils     10e9/l         0.0
Glucose       mmol/l         5.6
Vitamin D*    nmol/l         18
* Not authorized yet
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Offline Green

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8875 on: 18/08/2010 16:13:38 »
Quote from: Vandemolen3 on 18/08/2010 15:30:54
Result of blood tests:

TSH           mU/L           4.3 (was 4.7)
Free T4       pmol/l         11 (was 12)
Testosterone  nmol/L         11
Prolactin     U/l            0.17
Progesterone  nmol/l         1.4

Hemoglobin    nmol/l         8.9
Hermatocriet  rel.fract      0.42
MCV           fl               84
MCH           fmol           1.78
erythrocytes  10e12/l        5.00
platelets     10e9/l         184
leukocytes    10e9/l         6.1
Neutrophils   10e9/l         4.1
Lymphocytes   10e9/l         1.6
Monocytes     10e9/l         0.3
Eosinophils   10e9/l         0.1
Basophils     10e9/l         0.0
Glucose       mmol/l         5.6
Vitamin D*    nmol/l         18
* Not authorized yet

Do you have the lab ranges?

The results are very dependant on the lab assay used.

All of this stuff is pretty new to me, but the vitd looks deficient and the testosterone looks be a little on the lower side.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8876 on: 18/08/2010 16:48:54 »
Quote from: green on 18/08/2010 16:13:38
Quote from: Vandemolen3 on 18/08/2010 15:30:54
Result of blood tests:

TSH           mU/L           4.3 (was 4.7)
Free T4       pmol/l         11 (was 12)
Testosterone  nmol/L         11
Prolactin     U/l            0.17
Progesterone  nmol/l         1.4

Hemoglobin    nmol/l         8.9
Hermatocriet  rel.fract      0.42
MCV           fl               84
MCH           fmol           1.78
erythrocytes  10e12/l        5.00
platelets     10e9/l         184
leukocytes    10e9/l         6.1
Neutrophils   10e9/l         4.1
Lymphocytes   10e9/l         1.6
Monocytes     10e9/l         0.3
Eosinophils   10e9/l         0.1
Basophils     10e9/l         0.0
Glucose       mmol/l         5.6
Vitamin D*    nmol/l         18
* Not authorized yet

Do you have the lab ranges?

The results are very dependant on the lab assay used.

All of this stuff is pretty new to me, but the vitd looks deficient and the testosterone looks be a little on the lower side.
No this all there was on the form.

VitD: I will call my familydoctor when the result is final.
Testosterone: 6-12 is normal/ on the lower side
A familydoctor will not intervene my himself when the TT is 11. Maybe I have to ask him myself for a test treatment. Or do you know if there 's a vitamin/ pills/ food diet you can buy to bring Testosterone up?

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8877 on: 18/08/2010 17:49:11 »
POIS turns up in the strangest places!
http://itsonlyfashionblog.com/2010/08/17/its-a-mens-sweater-i-dont-care/

lol, see first paragraph.
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Offline reuniting

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8878 on: 18/08/2010 19:34:40 »
My site has a lot of visitors with various post-orgasmic complaints, although its focus is different (sexual relationships). I'm therefore always interested in the experiences of people struggling with POIS.

I know there's a belief that a pill will cure POIS, but it's actually looking like the situation is more complex than that. While we're waiting for science to figure it out, I'd just like to report on a behavioral approach that might offer comfort for some of you.

I know intimate relationships can be fear-producing when severe post-orgasmic symptoms will inevitably follow orgasm. Just keep in mind that many lovers experience milder forms of neurochemical shifts and related mood and perception changes after orgasm, too. Here's an account of a very sexually active woman (28) who decided to play around with the concept of sex play without orgasm. It might offer you another way of coping. http://www.reuniting.info/node/4466 [nofollow]

As tribal, pair-bonding primates, we humans get a lot of rewards from friendly interaction, whether with a lover or other companions (pets can help too). The latest research on this point shows that having a mate reduces cortisol levels during stress. http://scienceblog.com/37587/marriage-and-committed-romance-reduce-stress-related-hormone-production/ [nofollow] I share this because I suspect that one way to improve neurochemical balance, and reduce symptoms, is to increase the degree of connection with others.

Intriguingly, the ancient Chinese sexologists observed that "frequent sex with occasional ejaculation is less depleting than occasional sex with habitual ejaculation." It may be that frequent affection with virtually no orgasm is an ideal path for those whose brains are very sensitive to the neurochemical changes after orgasm.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8879 on: 18/08/2010 19:50:52 »
Quote from: Guthrie on 20/07/2010 20:08:42
Quote from: Dr. Matt on 20/07/2010 19:20:48
Vitamin D results were extremely low

That makes five cases now of low vitamin D!
Make that six cases. My Vitamin D is also extremely low: 18. It should be at least 30.
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