[Green]

I will gladly post up the ACTH test results as soon as I get them, but for that it's going to be quite a waiting game, my next endo appointment is early November, I'll see if I can get it moved to an earlier date, it's pretty stressful waiting around for results.

Maybe you can call for the results. They have the results in 1 up to 2 weeks max.
Tommorow I will call my familydoctor to send me to the endo. I will ask for a cortisol research and a mri scan for adrenal glands or the pituitary.

It's quite complicated interpreting them results I'm told. The first point of contact to get the results is my GP, I'll need to pay a visit later this week to get the results of the retest of the previous panel I had done, I'll see if I can get a hold of the ACTH sim results also, I've got a feeling they'll be raw numbers like the last set of results that were faxed over, making it very difficult to interpet.

Hopefully your doctor will realise that you're suffering and will send you to an endo for an investigation, I believe POIS is heavily tied into the endocrine system, so an endo will be the most appropriate specialist.

[demografx]

Heart problems? Demo is still alive. Haha.

No! I am writing this from The Great Beyond.

There is POIS in heaven also?  [:-'(] Dooomed.

Who said I was UP there???  []

[demografx]

(re-post)
 
Hi, POIS members and newcomers!

I've created an online CHAT ROOM called "POIS".
Please join or start the realtime discussion! This way we can perhaps get to know each other better and facilitate The POIS Cure(s) Of The Century! []

The best way into the Chat Room is at the following URL:
http://forums.delphiforums.com/POIS/chat

I don't have to be there. Just feel free to use this as your "POIS Lounge"! Whenever you want! Invite or join a co-member(s) from our POIS Forum for a more informal and realtime chat/discussion of your theories, wishes, ideas and thoughts.

[Green]

Heart problems? Demo is still alive. Haha.

No! I am writing this from The Great Beyond.

There is POIS in heaven also?  [:-'(] Dooomed.

Who said I was UP there???  []

Oh dear  [:0]

[demografx]

 [] [] []

[demografx]

My POIS cure - update

Approaching two years now, I will say that my daily testosterone + stimulants treatment is more along the line of 80% than 90% effective. The biggest complication is the extreme jump in libido, which makes comparison to the past difficult.

I am very grateful to this forum for making it possible. Thank you!

[Green]

What do you think of my Syndrome of Cushing-theory?

Looked into this in the past but wasn't fully satisfied POIS was down to Cushing's, my last recorded Cortisol level was well into the lower half of the range, but this was two months after masturbation/sex induced POIS.

I don't know anyone with Cushing's syndrome, but briefly looking on the internet can't find any posts pertaining to worsening symptoms after sex or masturbation.

Taken from; http://www.patient.co.uk/health/Cushing's-Syndrome.htm [I assume the symptoms list is cited] these are some of the symptoms.

Obesity - with fat around the main body area (trunk) rather than the arms and legs. The arms and legs can become quite thin compared with the obese body.
I am not at all obese, there is a collection of fat around my trunk lately, but this is down to some of the medications I'm on and also a lack of exercise recently due to a back injury. My legs are quite muscular, down the amount of cycling I do, my arms are also not thin. I have a lot of stomach bloat, my waist can fluctuate quite a few inches.

Facial puffiness, and the face often looks redder than usual.
This happens in POIS, my face becomes round and puffy, facial features usually return a month after POIS, face does not look redder in POIS although

Diabetes.
I'm not aware I have that

Facial hair in women.
Doesn't apply [|)]

High blood pressure.
I take beta blockers, I have seen it high as ~150/90 and low as 105/55 blood pressure although normally falls into the normal range

Muscle weakness. In particular a proximal muscle weakness. The proximal muscles are the ones in your arms and legs nearest to the body. So, the muscles around the thigh, pelvis, shoulders and upper arms are the proximal muscles.
Shoulder muscles are pretty weak because of a kyphotic curve, it's irritable and somedays I take pain killers, in POIS I struggle to brush my teeth for a minute or two

Thin skin which bruises easily.
I've always had thin skin, I get cut VERY easily, but I rarely bruise. This is significantly exaggerated during POIS

Purple/pink stretch marks (striae) may appear - similar to those seen on some pregnant women.
I have stretch marks around my stomach and biceps, slightly purple stretch marks in lower abdomen, but stretch marks are white on biceps.

Tiredness.
Synonymous with POIS

Aches and pains - particularly backache.
Kyphosis related muscle pain on my back, joints are VERY painful in POIS but after a month or so fluidity return, albeit still weak

Mood swings - such as being more irritable, depressed, or anxious than usual.
I have very little tolerance to stress, most things build up into an anxiety which I'm unable to account for, I'm very sure this is down to the very low testosterone level I've got <215ng/dl

Lack of sex drive (libido).
[:-'(] [:-'(] [:-'(]

Osteoporosis ('brittle bones'). You may fracture a bone more easily than usual.
Last time I had a confirmed broken bone was, when I was 1 years old and tumbled down a flight of stars, I've since fallen off my bike/sporting had related injures, none of which have caused any broken bones, altough my bones are thin, possibly down to low vit D

Oedema ('water retention') around the ankles.
none

Excess thirst.
Only in POIS

More susceptible to infections.
Sinus infection and UTI's hmmm...

Affected children tend to be obese, but grow slowly so are short for their age.
During childhood I was always underweight

All the research I've done points to POIS being a endocrine related illness, I'm not totally convinced it's Cushing's syndrome, but if a few more POIS suffers can do the above, then it might warrant looking into Cushing's more deeply.

If I was to play Where's Waldo then, I'd look into the full spectrum, sequence of orgasm and arousal and work with existing results, but that appears to be complicated, and for someone who has very little interest in biology, bar POIS I'm not going to get far, I'm going to try though.  [^]

[Vandemolen3]

What do you think of my Syndrome of Cushing-theory?

Looked into this in the past but wasn't fully satisfied POIS was down to Cushing's, my last recorded Cortisol level was well into the lower half of the range, but this was two months after masturbation/sex induced POIS.

I don't know anyone with Cushing's syndrome, but briefly looking on the internet can't find any posts pertaining to worsening symptoms after sex or masturbation.

Taken from; http://www.patient.co.uk/health/Cushing's-Syndrome.htm [I assume the symptoms list is cited] these are some of the symptoms.

Obesity - with fat around the main body area (trunk) rather than the arms and legs. The arms and legs can become quite thin compared with the obese body.
I am not at all obese, there is a collection of fat around my trunk lately, but this is down to some of the medications I'm on and also a lack of exercise recently due to a back injury. My legs are quite muscular, down the amount of cycling I do, my arms are also not thin. I have a lot of stomach bloat, my waist can fluctuate quite a few inches.

Facial puffiness, and the face often looks redder than usual.
This happens in POIS, my face becomes round and puffy, facial features usually return a month after POIS, face does not look redder in POIS although

Diabetes.
I'm not aware I have that

Facial hair in women.
Doesn't apply [|)]

High blood pressure.
I take beta blockers, I have seen it high as ~150/90 and low as 105/55 blood pressure although normally falls into the normal range

Muscle weakness. In particular a proximal muscle weakness. The proximal muscles are the ones in your arms and legs nearest to the body. So, the muscles around the thigh, pelvis, shoulders and upper arms are the proximal muscles.
Shoulder muscles are pretty weak because of a kyphotic curve, it's irritable and somedays I take pain killers, in POIS I struggle to brush my teeth for a minute or two

Thin skin which bruises easily.
I've always had thin skin, I get cut VERY easily, but I rarely bruise. This is significantly exaggerated during POIS

Purple/pink stretch marks (striae) may appear - similar to those seen on some pregnant women.
I have stretch marks around my stomach and biceps, slightly purple stretch marks in lower abdomen, but stretch marks are white on biceps.

Tiredness.
Synonymous with POIS

Aches and pains - particularly backache.
Kyphosis related muscle pain on my back, joints are VERY painful in POIS but after a month or so fluidity return, albeit still weak

Mood swings - such as being more irritable, depressed, or anxious than usual.
I have very little tolerance to stress, most things build up into an anxiety which I'm unable to account for, I'm very sure this is down to the very low testosterone level I've got <215ng/dl

Lack of sex drive (libido).
[:-'(] [:-'(] [:-'(]

Osteoporosis ('brittle bones'). You may fracture a bone more easily than usual.
Last time I had a confirmed broken bone was, when I was 1 years old and tumbled down a flight of stars, I've since fallen off my bike/sporting had related injures, none of which have caused any broken bones, altough my bones are thin, possibly down to low vit D

Oedema ('water retention') around the ankles.
none

Excess thirst.
No, never

More susceptible to infections.
Sinus infection and UTI's hmmm...

Affected children tend to be obese, but grow slowly so are short for their age.
During childhood I was always underweight

All the research I've done points to POIS being a endocrine related illness, I'm not totally convinced it's Cushing's syndrome, but if a few more POIS suffers can do the above, then it might warrant looking into Cushing's more deeply.

If I was to play Where's Waldo then, I'd look into the full spectrum, sequence of orgasm and arousal and work with existing results, but that appears to be complicated, and for someone who has very little interest in biology, bar POIS I'm not going to get far, I'm going to try though.  [^]

Green, when I read the article about Cushing on Wikipedia I saw that 1 symptom is purple stripes around the abdomen. And then I thought: I don't have that, so I don't have Cushing. But a week later I read that you don't have to have all the sympoms.
And diabetes is not a symptom of Cushing. But Cushing may lead in the long term to diabetes.

I've got a few symptoms of Cushing such as acne and I gained in weight in a short time (20 kg in 4 years).

You have to check your cortisol shortly after an O. Because an O increases cortisol. Maybe POIS isn't exactly Cushing, but their are a lot of similarities.

[Vandemolen3]

My Cushing-check:

Obesity - with fat around the main body area (trunk) rather than the arms and legs. The arms and legs can become quite thin compared with the obese body.
I have a little overweight. My arms and legs are slim. Bu I've a little belly.

Facial puffiness, and the face often looks redder than usual.
Little round face. Redder in POIS because of some burst blood vessels.

Diabetes.
No. I've checked this. But as I said, diabetes could be a long term effect of Cushing.

High blood pressure.
I don't know this. I think so because the last years I am a little stressed.

Muscle weakness. In particular a proximal muscle weakness. The proximal muscles are the ones in your arms and legs nearest to the body. So, the muscles around the thigh, pelvis, shoulders and upper arms are the proximal muscles.
Muscles and joints hurt. Most in POIS.

Thin skin which bruises easily.
I don't know. Don't think so.

Purple/pink stretch marks (striae) may appear - similar to those seen on some pregnant women.
No.

Tiredness.
Yes. Aggravated by POIS.

Aches and pains - particularly backache.
Yes.

Mood swings - such as being more irritable, depressed, or anxious than usual.
Yes.

Lack of sex drive (libido).
Yes in the last year it went down a lot. 

Osteoporosis ('brittle bones'). You may fracture a bone more easily than usual.
Not that I know.

Oedema ('water retention') around the ankles.
No. But I have moist eyes in POIS.

Excess thirst.
Yes, most in POIS.

More susceptible to infections.
Sinus infection and UTI's.

Affected children tend to be obese, but grow slowly so are short for their age.
During childhood I was always underweight and small.

Acne especially on the back
Yes, especially on the back. I get more acne after an O.

[demografx]

What do you think of my Syndrome of Cushing-theory?

Looked into this in the past but wasn't fully satisfied POIS was down to Cushing's, my last recorded Cortisol level was well into the lower half of the range, but this was two months after masturbation/sex induced POIS.

I don't know anyone with Cushing's syndrome, but briefly looking on the internet can't find any posts pertaining to worsening symptoms after sex or masturbation.

Taken from; http://www.patient.co.uk/health/Cushing's-Syndrome.htm [I assume the symptoms list is cited] these are some of the symptoms.

Obesity - with fat around the main body area (trunk) rather than the arms and legs. The arms and legs can become quite thin compared with the obese body.
I am not at all obese, there is a collection of fat around my trunk lately, but this is down to some of the medications I'm on and also a lack of exercise recently due to a back injury. My legs are quite muscular, down the amount of cycling I do, my arms are also not thin. I have a lot of stomach bloat, my waist can fluctuate quite a few inches.

Facial puffiness, and the face often looks redder than usual.
This happens in POIS, my face becomes round and puffy, facial features usually return a month after POIS, face does not look redder in POIS although

Diabetes.
I'm not aware I have that

Facial hair in women.
Doesn't apply [|)]

High blood pressure.
I take beta blockers, I have seen it high as ~150/90 and low as 105/55 blood pressure although normally falls into the normal range

Muscle weakness. In particular a proximal muscle weakness. The proximal muscles are the ones in your arms and legs nearest to the body. So, the muscles around the thigh, pelvis, shoulders and upper arms are the proximal muscles.
Shoulder muscles are pretty weak because of a kyphotic curve, it's irritable and somedays I take pain killers, in POIS I struggle to brush my teeth for a minute or two

Thin skin which bruises easily.
I've always had thin skin, I get cut VERY easily, but I rarely bruise. This is significantly exaggerated during POIS

Purple/pink stretch marks (striae) may appear - similar to those seen on some pregnant women.
I have stretch marks around my stomach and biceps, slightly purple stretch marks in lower abdomen, but stretch marks are white on biceps.

Tiredness.
Synonymous with POIS

Aches and pains - particularly backache.
Kyphosis related muscle pain on my back, joints are VERY painful in POIS but after a month or so fluidity return, albeit still weak

Mood swings - such as being more irritable, depressed, or anxious than usual.
I have very little tolerance to stress, most things build up into an anxiety which I'm unable to account for, I'm very sure this is down to the very low testosterone level I've got <215ng/dl

Lack of sex drive (libido).
[:-'(] [:-'(] [:-'(]

Osteoporosis ('brittle bones'). You may fracture a bone more easily than usual.
Last time I had a confirmed broken bone was, when I was 1 years old and tumbled down a flight of stars, I've since fallen off my bike/sporting had related injures, none of which have caused any broken bones, altough my bones are thin, possibly down to low vit D

Oedema ('water retention') around the ankles.
none

Excess thirst.
Only in POIS

More susceptible to infections.
Sinus infection and UTI's hmmm...

Affected children tend to be obese, but grow slowly so are short for their age.
During childhood I was always underweight

All the research I've done points to POIS being a endocrine related illness, I'm not totally convinced it's Cushing's syndrome, but if a few more POIS suffers can do the above, then it might warrant looking into Cushing's more deeply.

If I was to play Where's Waldo then, I'd look into the full spectrum, sequence of orgasm and arousal and work with existing results, but that appears to be complicated, and for someone who has very little interest in biology, bar POIS I'm not going to get far, I'm going to try though.  [^]

Thanks for the analysis, green!

[lauracostis]

i am luckily Cushing syndrome free

[Vandemolen3]

i am luckily Cushing syndrome free

How do you know that? The only way to know it for sure is to let your cortisol checked. And to make a scan of your adrenal glands and the pituitary.

[demografx]

B_Jim, POIS inconsistencies are unlike any I've ever encountered! Rules for one individual are broken for another.

[demografx]

Supracarbohydrate POIS treatment!  []

Yesterday, I was impatient waiting for my 80% to 90% POIS cure, so I experimented to hasten the cure with a heavy dose of carbohydrates!

Lots of lasagna. Iced espresso. Large oatmeal cookie.

It seemed to work! (Placebo effect? Maybe [])

Placebo or not, some of you may recall, that I have always historically craved carbohydrates at POIS onset. I realize that this goes counter to some of your experiences that indicate that carbohydrates can be POISon. []

It's really strange ! But it's a good thing if it works for you.
I think carbs may help you with concentration/cognition and less with allergy-like symptoms and itching, isn't it ?

My symptoms have been decreased a lot since I reduce and I chose my carbs. I often have some symptoms 30 or 45 min after meals that's why the influence of glycemia is clear.

I noticed the glycemia after heart surgery, I was frequently given insulin to counter it.

[GoingCrazy]

I really regret the three o's i had yesterday.  It's like i completely forget I have this disease.  My god I want this study to come out.

By the way, I went to the doctors to get tested for lyme disease yesterday, they should know within a week.

[John21 (OP)]

Update:
I had an O last Friday. I remained stable until Monday when I felt some of my old symptoms. It felt like too much of something was being released, I could sense my cognition being affected by the change, and my neck glands felt a little swollen. Who knows, maybe it is excessive cortisol being released, doesn't it supress the immune system? I am on nutmeg and I noticed that my reaction to it was less noticeable in the state, so I upped my intake and the next day the POIS "feeling" was not present, so maybe this might be an effective supplement for us. I will be interested in hearing if it helps others. I was taking 1/8 teaspoon daily, and I upped it to about 3/8 to 1/4 teaspoon temporarily.

[GoingCrazy]

Update:
I had an O last Friday. I remained stable until Monday when I felt some of my old symptoms. It felt like too much of something was being released, I could sense my cognition being affected by the change, and my neck glands felt a little swollen. Who knows, maybe it is excessive cortisol being released, doesn't it supress the immune system? I am on nutmeg and I noticed that my reaction to it was less noticeable in the state, so I upped my intake and the next day the POIS "feeling" was not present, so maybe this might be an effective supplement for us. I will be interested in hearing if it helps others. I was taking 1/8 teaspoon daily, and I upped it to about 3/8 to 1/4 teaspoon temporarily.

I'm going to try this nutmeg

[GoingCrazy]

Update:
I had an O last Friday. I remained stable until Monday when I felt some of my old symptoms. It felt like too much of something was being released, I could sense my cognition being affected by the change, and my neck glands felt a little swollen. Who knows, maybe it is excessive cortisol being released, doesn't it supress the immune system? I am on nutmeg and I noticed that my reaction to it was less noticeable in the state, so I upped my intake and the next day the POIS "feeling" was not present, so maybe this might be an effective supplement for us. I will be interested in hearing if it helps others. I was taking 1/8 teaspoon daily, and I upped it to about 3/8 to 1/4 teaspoon temporarily.

I'm going to try this nutmeg

I just tried some, it actually seems to create some numbing sensations (in my mouth at least) and I actually immediately do feel a bit better.  But what method do you use to eat it?  I am just ingesting it straight out of the carton.

I feel pretty high right now... haha, didn't read that health benefit

[Vandemolen3]

Be carefull with nutmeg. An overdose nutmeg can be deadly!

For the people who believe the high cortisol theory:
Caffeine raises the cortisol level.

Ginseng and Relora brings cortisol down. Ginseng is Chinese.

The best way to lower the cortisol level is to stay relaxed, don't stress.

I am not going to try Relora or Ginseng before a urine test of my cortisol. Tommorow I will go to my specialist and ask for a test or he has to make an appointment about a week. He doesn't know why I have so many UTI's. Well I know, because of the high Cortisol.

[GoingCrazy]

Be carefull with nutmeg. An overdose nutmeg can be deadly!

For the people who believe the high cortisol theory:
Caffeine raises the cortisol level.

Ginseng and Relora brings cortisol down. Ginseng is Chinese.

The best way to lower the cortisol level is to stay relaxed, don't stress.

I am not going to try Relora or Ginseng before a urine test of my cortisol. Tommorow I will go to my specialist and ask for a test or he has to make an appointment about a week. He doesn't know why I have so many UTI's. Well I know, because of the high Cortisol.

Thanks for that vandemolen.  I was actually considering just taking the whole bottle 0_o

I support the cortisol theory too, as I thought my POIS began with the consumption of coffee.

I used to drink Ginseng A lot, but stopped, don't really know why I'm going to try drinking it again though.

Another reason I support the cortisol theory is because when I gamble, play highly competitive games, I can feel the POIS a lot more.  But, a reason that I doubt it is cortisol is because of my body weight, I am pretty thin, and I read that cortisol causes excess weight gain.