[demografx]

II would be more willing to believe that ONE of the medications is helping you vs a combination. You say you have tried stimulants alone and they did not help, okay. Have you tried testosterone alone without any other meds? Perhaps it is pivotal in the syndrome.

John

just curious, John, why do you think a single med is more believable than a combination?

[John21 (OP)]

demografx, it just sounds more logical to me. Perhaps I'm wrong, but it seems like the odds of taking the right combination would be much lower than the odds that one of the meds is helping you.

John

[demografx]

JP's PROFILE QUESTION

I agree with JP that if we learn more about each others' shared traits and similarities, we may learn more about POIS contributing factors.

I won't lay out my life story here, but I'll try to check in time to time with tidbits that may be relevant.

I suffer terrible jet lag, almost like POIS. The most disturbing part is an incredibly intense feeling of disorientation, particularly after the return home. Like the proverbial fish out of water. It can last a week on both sides.

Depression and ADD have periodically been problems as I noted earlier.

POIS has ruined a good chunk of my life, either beause of active symptoms or "hanging over my head" like a curse.

Enough for now, thanks

[Dave23]

Hi,

Thank you all for this very helpful thread.

What is the most effective dose amount you have experienced on Levitra for treating POIS ?

Also does anyone know what was the effective dose
of taking Zoloft that cured the mans POIS ?

I have had POIS since around 19 and also P.D since 15-16.

At its worst the POIS
symptoms would last a week. Now not so bad, 1-3 days
post ejaculation.

Started TRT 7 weeks ago plus HCG and an AI in Aromasin to help balance my hormone levels.

Iam on :

Testosterone cypionate at 32mg E2D schedule and 250ius of HCG E2D.

Dostinex at 125mcg ED and on ejaculation days at 500mcg. I have high prolactin levels. Side effects for 2 weeks of brain fog.

Im also on Isocort for low morning cortisol levels and Armour for low T3+T4 levels. Have been on for 8 weeks.

Before :

Energy for physical exercises : 1-2x a week

Ejaculation frequenzy : Once every week/2

POIS period : 4-7 days

Now :

Energy for physical exercises : 3-4x a week

Ejaculation frequenzy : Once every 4-5 days.

POIS period : 1-3  days

Have already ordered Levitra and Zoloft. Will experiment with these and post results and side effects.

[demografx]

DISAPPOINTED

Yesterday was POIS Day 1. I took Cialis (after ejac.) on Day Zero. Cialis has a longer lasting effect than Levitra. My fervent hope was that Cialis would be "the silver bullet," the cure (for me and perhaps others) for this nasty POIS business.

Boy, was I wrong! It was a day of severe exhaustion. And moderate depression. I was at a coffee shop for most of the day with my computer, on and off socializing with patrons. I would've been better off in bed! Tons of coffee succeeded only in making me hyper and nauseous.

My wife suggested exercising. She just doesn't understand that I simply have no energy when I'm like this. Has anyone had positive results excercising during POIS symptoms?

I'm not giving up. I emailed my psychiatrist to ask if it's possible that Levitra has a basically different chemical makeup than Cialis that would make it less effective for POIS(he hasn't responded yet). I will see him day after tomorrow, Thursday.

Maybe Levitra is still the key, I don't know. I am typing this right now from bed - conserving energy - on Day Two. I do feel better than yesterday, though.

Sorry to post my setback. Hope to have better news next time.

[demografx]

Hi,

Thank you all for this very helpful thread.

demo, what is the most effective dose amount you have experienced on Levitra for treating POIS ?............

....I have had...P.D since 15-16.

....Started TRT 7 weeks ago plus HCG and an AI in Aromasin to help balance my hormone levels.......................

....Have already ordered Levitra and Zoloft. Will experiment with these and post results and side effects.

Hi DAVE, thank you for posting and welcome! I was prescribed Levitra 10 mg for ED. It wasn't prescribed for POIS. It just turned out to be an "accidental" side-benefit.

Would you kindly explain what "P.D....TRT 7...HCG...AI" mean?

Re. Levitra and Zoloft, I hope you will do that under doctor supervision. As I mentioned to JP, I have no idea if Levitra can be potentially harmful at a young age where ED is not an issue.

Thanks again,
demografx

[jplewin]

Hi all... welcome Dave

Yesterday, fell asleep without taking my medication. Result, wet dream and POIS for today. What an idiot... another day of trash.
... I've tried working out in a gym. My mom used to insist, as your wife does, that I should do exercise. I can assure you it does not help in any way, only to distract your mind. At the best you will feel more tired and will sleep earlier so the day ends fast.
Hope that today goes fast so tomorrow I'd be Ok... hope so.

JP

[demografx]

JP

BEST WISHES FOR A SPEEDY POIS RECOVERY!!

[demografx]

EXPECT LESS OF YOURSELF DURING POIS

My psychiatrist suggested this and it's been helpful so I thought I'd pass it on to you all.

[John21 (OP)]

Day 0 today (had a nocturnal this morning before waking). I can definitely feel the difference, being blank minded, but it isn't too problematic. In my POIS I find it quite difficult to work alongside someone during the day, as the extra work of communication puts a huge load on my mind, I have to mentally work hard to try to keep up. Today I was able to work on my own so anxiety was kept low. I find it very important to keep anxiety low in this POIS state. I think it is the anxiety of dealing with it (working hard to appear mentally "there") that causes the second phase of my syndrome, the burnout phase.

My POIS is still present, but I am adamant that my experience is not nearly as severe as it used to be, before I stopped consuming milk. I have absolutely no explanation for this, just another weird piece of this puzzle that somehow goes together. Any ideas of what might cause this anyone? It may be an important clue to what is going on with all of us. I would suggest that anyone with POIS try going off dairy for a month or two. 

Hopefully tomorrow will go easy on me )

John

[Dave23]

[/quote]

Hi demografx, thank you for your welcome!

Would you kindly explain what "P.D....TRT 7...HCG...AI" mean?

P.D = Peyronies Disease

Penile Scarring, curvature, ED, Leakage, inflammation pain, penile dents all mixed in one.

TRT = Testosterone Replacement Therapy

Iam on 32mg (E2D) Every 2 days schedule to maintain consistant testosterone levels and to keep side effects(Mainly Aromatasing) low or non existant.

HCG = Human chorionic gonadotropin

250iu E2D.

Signals the brains LH hormone gland to keep naturally producing testosterone and sperm
so I dont become infertile and also to
prevent the boys from shrinking.


AI = Aromatase Inhibitor

Aromasin 10mg ED.

To Lower estrogen levels.

Have started 5htp (150mg) and Gaba (400mg) 3 times a week. Will post results if any.

Thanks again,
Dave
[/quote]

[demografx]

Personally I am chaste now and avoid the problem altogether.

I tried to be chaste many many times. It "works" but it is just too hard to STOP completely. Even though it relieves POIS, it creates another form of anxiety/depression as someone else pointed out here. Isn't this a kick in the head??? We can't "win" either way !!!!!

[demografx]

Day 0 today

I would suggest that anyone with POIS try going off dairy for a month or two. 

Hopefully tomorrow will go easy on me )

John

Best wishes for tomorrow, John!! (I'm also starting to "come back" from the dead myself LOL!)

My wife suggested cutting out milk, I hate to admit she's right!  []  But you, John, have credibility so I have to find a way to try it!(wife or no wife haha)

[demografx]

MILK/DAIRY

Cutting it out, as John suggests. Starting last night.

[demografx]

CYMBALTA

My psychiatrist pointed out today that it looks like Cymbalta is NOT effective for my POIS, because in this last devastating round of POIS suffering - hoping that Cialis would work, but it didn't - the Cymbalta didn't work.

My hope is now with Levitra and/or quitting milk/dairy.
And perhaps other successful results by others here.

[jplewin]

Frustrated...

Does anybody know someone who has recovered from this???

JP

[demografx]

Frustrated...

Does anybody know someone who has recovered from this???

JP

JP, I think B_Jim mentioned someone who was "cured" with Zoloft.

B_JIM: is what I just said correct?

Thanks,
demografx

[demografx]

TO JP

JP, I feel just like you do, very frustrated. I have had this for at least 25 years (!) and I STILL have a difficult time believing this is happening to me. In fact for many years, I REFUSED to believe this was happening to me, I was in such great denial - especially since one doctor/psychiatrist/psychologist/urologist after another had absolutely nothing to offer to alleviate the POIS suffering.

JP, the pain is somehow compounded I think when no one understands what you have!!!

The only thing we can do is be hopeful and not give up.

Although I am in shock over this last POIS episode (I just don't know why it was so BAD!, maybe it was the letdown after I had such great hopes for Cialis to work) I will go back to testing Levitra, which seemed to improve the condition.

Let's stay in touch, you have my address.

Best wishes,
demografx

[demografx]

Yes that's what i said but maybe "cured" is not the correct word. Zoloft has removed all his post orgasm symptoms.

Sorry, B_Jim, but I'm still just a little bit confused...can you please clarify: what is the difference between "cured" and "removed all his POIS symptoms"? To me, they both mean the same thing, i.e., with Zoloft, he no longer has post-orgasmic difficulties/problems.... Is that accurate?

Thanks again,
demografx

[John21 (OP)]

Listen guys I don't think that I am totally "cured" because at times I can still feel some of the effects in a minor way, but the severity has diminished from a 9.99 to a .9 on a scale from 1-10, and sometimes I experience no effect. As I repeat, I am convinced that milk is linked somehow. I'll let you all know how I arrived at this conclusion.

For many years I tried many things, every day of my life was focused around either coping with this problem (suffering, hiding it, trying to appear normal) and trying to find a solution. I went from doctor to doctor to doctor, test to test to test. One idea I had was that my horrible experience was due to a prostate infection. This idea had merit as PE can be caused by infection. So my doctor put me on antibiotics for months to experiment. And... it worked, so I thought for sure I had found the problem. Then, later I went off the medication and my symptoms came back. Honestly I can't remember what my thoughts were at that point, whether I wanted to go back on antibiotics, but I was aware that the only other thing that I had changed was that I quit drinking milk during the time I was taking the medication because milk would have reduced the amount of antibiotics absorbed. So, I did a trial of just quitting milk, and voila.

But still I can't understand it. As if my original problem wasn't strange enough, the "solution" was even stranger. I don't think that the problem is "gone", but just greatly diminished. When I started this thread I must have been going through a minor episode, I don't recall. As I said I am chaste now, but occasionally have NEs. I rarely have NEs if I keep my mind away from anything that would lead me to think of erotic images, not even prime time television dramas that would make me excited. This week I had one, and I have been feeling quite well. I definitely notice the change in my mind, but I suspect it to be what "normal" people experience, feeling more relaxed in the days following sex. I get the sense that my mind perhaps relaxes too much, but it is tolerable. I just makes me a little less quick on the draw mentally, which in turn causes anxiety. So I end up with a relaxed mind getting anxious, and a relaxed mind has more power somehow, so the anxiety can approach panic sometimes when I start to worry. Due to this having a good work environment is crucial to my well being.

John