[pauliebaby61]

My lyme dr, [Dr. Domminck Braccia, D.O. from Haverford, Pa. ph # 610-924-0600] was trying to help me with this'fatigue after orgasm' problem [thats what i called it] and told me he felt it could be neurotransmitter related, because the body releases hisamine at orgasm.  You can google it and will find this to be accurate. He ordered several neurotransmitter tests, via stool sample from Doctors Data. The results did show some deficiencies, most being Dopamine and seratonin.
My dr has put me on 5HTP[ precurser that makes Dopamine and seratonin  to see if it helps. So far, no difference, but his idea is worth exploring. It could be the release confuses the brain, and instead of sex being a good experience, it shuts down function and makes it a very negative one. Sounds like a nuerotransmitter imbalance of some kind to me. Ive been trying to figure this out on my own for 10yrs, because all the doctors look at me like im nuts, and tell me they never heard of this.
This is why i asked 'goingcrazy' about him feeling good after taking benadryl. If this is true, perhaps the benadryl[or any anti-histamine] blocks the hisamine from confusing the brain???
For years, I assumed this was an adrenal problem, due to low function, because adrenal insuffiency has very similar symptoms, but i have been on hydrocortisone for 10 yrs and prednisone for a month and it does NOT help this issue. Also have been on thyroid to no avail. Ativan helps the anxiety greatly.
I had undiagnosed Lyme for 25yrs before i got treatment, so it could be in my case the lyme has really screwed up my body, because my hormones are so wacked out....

[GoingCrazy]

The histamine release is a very good starting point to explain Pois.

I tried it (benadryl) yesterday in POIS and it had no effect, maybe if you take it beforehand it might do something.

Benadryl prevents release of histamine but doesn't effect it if its already there?

I had undiagnosed Lyme for 25yrs before i got treatment, so it could be in my case the lyme has really screwed up my body, because my hormones are so wacked out....

How do you manage to find that it was in your body for 25 years?

[pauliebaby61]

just re-looked at my neuro-tests from 4 months ago, and my histamine was high....mmmmm   ...and when the test was done, i hadnt had an orgasm for a long time. could it be orgasm and the release of histamine sends the level so high it is screwing with my brain.....?

[GoingCrazy]

Weird, I find the more I have POIS, the more I am on this website.  What's good news is I definitely feel at least twice as better than last year before finding this site,  I feel POIS is greatly reduced in pain and time, especially just after one "O" which may last about 2 days for me, especially after an NE which tends to be less harmful than a normal "O".  Once you've hit rock bottom there is nowhere to go but up, so I keep on telling myself it's always going to get better and better.

[pauliebaby61]

The lyme was found by a PCR[dna] test, and i was treated based upon that and symptoms. Chronic lyme many times doesnt show up in blood tests, and western blot test isnt reliable.
I was treated with I.V. roecephin, about 150 treatments. My health has improved, but the pois stuff never has gone away.
I am determined to solve this puzzle....

[GoingCrazy]

I am determined to solve this puzzle....

I always think if we can get ourselves into this, we can get ourselves out.  I think if I exercise every other day, and stay away from the downstairs, I can make great progress.  I remember back in the day when I used to "O", but I used to feel tiredness instead of anxiety, it gradually came on... Now I think I can gradually make it go off.  Hopefully, I just need to fully stay away for at least a year.

[pyropeach]

Benadryl prevents release of histamine but doesn't effect it if its already there?

Just to be clear here, antihistamines do not prevent the release of histamine, but rather block the histamine receptor sites.  This is why antihistamines work best when taken a few hours before exposure to allergens so it has a chance to bind to the histamine receptor sites before histamine binds. 

The histamine release is a very good starting point to explain Pois.

Yes, I completely agree!!

[THISFORUMROCKS!]

The histamine release is a very good starting point to explain Pois.

I also agree.

So far it has been easy for me to assume that histamine release, possibly leading to excess could be a problem. Along these lines, a diet low in histamines/histidine could be investigated on the intake side of the equation while factors that inhibit Diamine Oxidase (histamine breakdown) could be investigated on the other side. Apparently an unhealthy digestive tract can lead to high levels of bacteria produced histamine from the histidine in food.  

Conversely, after reading about the positive attributes of L-Histadine and histamines produced from it, I am also seriously considering if a lack of these substances could be a problem in our case; potentially caused by a bad immune reaction to them or by their lack of metabolization/utilization, or histamine receptor site issues for example. Maybe histamine does not have to be only helpful OR harmful in POIS cases but could be both depending on which processes are considered.

Notably cheese and therefore CHEESE SANDWICHES tend to be a food high in histamines which could explain why one furum member likes cheese sandwiches..

Here is one interesting article relating to food and histamines.

http://whfoods.org/genpage.php?tname=dailytip&dbid=246 [nofollow]

 

[demografx]

My lyme dr, [Dr. Domminck Braccia, D.O. from Haverford, Pa. ph # 610-924-0600]

That was very generous of you! Thank you for sharing the contact info!

Ive been trying to figure this out on my own for 10yrs, because all the doctors look at me like im nuts, and tell me they never heard of this.

If it's any consolation, I've been grappling with the same thing for 30+ years (could be 40+, but like most people here, I just didn't connect POIS symptoms to sex for a long time).

Doctors without a clue (and blaming us) - what a rude awakening THAT was!!!

[GoingCrazy]

I've been changing theories A LOT over the past few months and I would just like to know what people think about hormones being the cause of this... could it really create all of this mental confusion and mood?  Weird how something your body makes could be so detrimental for you.

When I POIS I feel like the first few seconds after orgasm is fine, then suddenly it's like almost too much is released, I get a very tense feeling in the back of my head.  Than POIS follows...

My new theory is the overactive gland theory

and... I posted the question on yahoo answers and somebody said it is because my brain grey matter is low?  Really?? []

[GoingCrazy]

http://www.anxietyinsights.info/overactive_brain_endorphin_system_linked_to_depression.htm

just found this, overactive endorphin system?  Maybe endorphins released during sexual climax results in this system to overactivate?

It is "a pain killer 3x more effective than morphine"

And I do realize that when in POIS I get these "good" feelings associated with the terrible POIS feeling, maybe endorphin release followed by my brain trying to get off the "drug" is what causes POIS.  Almost too many ideas.

[CertainlyPOIS]

goingcrazy

whoever answered must have minute grey matter for giving an answer like that.

[Itsmebutwho?]

Is it possible to have sex/masturbate (ejaculate) wrong way?

I have had many years many of these POIS symptoms, depression, very low mood, foggy mind, very introverted, very bad weakness in my body and mind, coldness, flu like feeling, concentration problems, pains everywhere in body, allergy symptoms and so on... all after 1-2 days from ejaculation. And recovery has taken always few days if i stay without ejaculating those days.

I have tried many solutions from here, totally changed how i eat and had lot of exercise, without much help. Well, i feel healthier but the POIS symptoms havent disappeared.

I also tested my testosterone levels, the result: 15.... quite low but not below limit.

Last few months i have been thinking that why i have had sometimes couple of weeks' periods that i havent felt POIS symptoms much at all. I noticed that during those days i have been masturbating different way, i have made it slowly, teasing myself, not letting ejaculation come fast.

I also noticed during these last months that i can ejaculate/masturbate/have sex different way than i have had done during my whole age. Most of my times i have masturbated/had sex as being very consciously what i have been doing as having sex or masturbated. I have controlled my body.

But now i have noticed, my body can do those things automatically, without i make my body do it. I usually use homemade vagina if im masturbating. Most of my times i have put my penis in and start to move my body and kept moving it. But now... I have noticed if i want to have sex, i put my penis in and hold it still, and watch some sexy babes, my body actually starts to move by itself, without i consciously do it by myself. I dont actually need to do it by myself, my body does it for me. All i need to do it just watch and enjoy.

How it all goes:

I put my penis into vagina, i may make some conscious movements by myself and watching something hot same time. I dont usually do it long time. I just stop or slow down my pace, relax my body/pelvis, then it happens, my body seems want to do it. My penis needs to get just little touch from the vagina around it and it makes my body move back and forward. I dont need to do it by myself. I let my body do so, and i keep watching my sexual objects.

There comes a point when my breath begins to get faster, and thats very important point. The point makes my body move faster and faster, my breath gets also faster and faster. I start to loose time and space, my body begins to get good feeling. Things around me blurs, my eyes which first wandered around on woman's body, actually goes out of control, and locks on usually woman pelvis/vagina. My body does it automatically, without i do anything, crazy speed and the breath feels also so weird...so fast, not normal what i have experienced during my past years as having sex/masturbated. Then i get my orgasm, it feels so great and relief... whats more, i really feel good after ejaculation.... that havent happened most of times my past years... And the good feel just continues.... Next day i feel still good, no much sadness, no much depression, and i have energy....im able to think..... it feels weird...

But if i do it fast way, consciously, and control my masturbation/sex moment ... the result is POIS symptoms.

I have kept thinking why it is so...? Does my body release more testosterony this way? And the 'wrong' way does something else/bad to my body?

Is the key just let animal insticts come alive, let off the control?  []

[Z_one]

Hello everyone,

I am new to the forum, though have been following up closely on it since a couple of months now....I am a 30 years old male and  POIS sufferer since almost 6 years.. yet I only truly understood what was happening to me when I discovered this forum one year ago and thus putting an end to endless speculations, doubts and assumptions......mostly and like many POIS sufferers, I had to endlessly explain, convince, repeat to doctors that what was happening to me was not psychological but physiological….thankfully now there is enough proof and thanks to this great forum that POIS is 100% real !

Though i have seen many propositions going from Fenugreek to Rerola as remedies as well as POIS theories such as nerodrelanine and auto-immune diseases….one thing is sure not everybody is alike and in my opinion they might be more than one cause that are all inter-related and leading to the same problem yet all post orgasmic,,,,

Meanwhile,

I was wondering whether anyone has tried "black seed oil" (Nigella Sativa}  ?.....I personally take two large spoons of it just at the beginning of my symptoms and it seems to be a great boost overall; especially if combined with any light juice such as lemon or orange juice.....mostly if taken continuously in safe doses and in intervals...I noticed that it considerably decreases overall symptoms (I would say by 75%) as well as recovery time by half....(From one week to three days)… I watch out, since too much of it can cause kidney disease just like too much of anything,,,,,

Also, and as obvious as it might sound....through trial and error...I got to notice the great benefits of a sunbath for a couple of hours,,,,i have done some research and found that sunrays have great healing benefits on the endocrine and immune systems and are often underestimate from fear of skin cancers....it accelerates healing and recharges the body with energy and mood.....I personally have found sunbaths very beneficial in decreasing recovery time....and boost overall energy...of course that is not an option for those living in cold weather countries; unless they take a break to Cuba or Dubai after each POIS.... [8D]...


In addition ,I noticed again and through trial and error and some logic...that a fully loaded banana milk shake with some whey protein & bee pollen or honey greatly assists the body in recovering from the symptoms and mostly reduces compulsive eating disorder since ....Whey in particular has many immune friendly properties if taken in reasonable amounts as well as provides the body with fullness and satiety,,,, So I think you might have guessed it , on weekends while I am half dead on the side of the pool, I always ask for a fully loaded banana milk shake with HONEY PLZ! 

Anyway, I am personally a great believer that for every illness there is a cure….yet if the cure if not directly pointed out by God must be digged  out by humans….As such I  like many others have declared war against POIS and I am gathering every bit and piece from this forum  and going to present all of  it to my GP & endocrinologist on Monday,,,,,,(Already done some blood tests waiting for results,,,,) I will sure post anything relevant once I finish my diagnosis…..

Last but not least....I just would like to remind everybody about the great health risks that herb supplements can cause....especially in what concerns drug-herb and herb-herb interaction....I recklessly took an anti-histamine drug combined with a couple of herbs and almost died that day from my symptoms....also too many herbs can slowly kill your kidneys or liver without you noticing the early stage symptoms….and therefore too much trial and errors might have fatal consequences….

Finaly, I personally would like to thank the initiators of this forum including all those who shared their stories whether fully cured or not…..also special thanks to Girlwind for that great video on youtube,,,,I truly think that if each and every POIS sufferer including myself  does enough noise to create awareness for this life ruining illness,,,,,that media, specialists, doctors, health associations will look even more seriously into POIS and hopefully thrive to find us a clear concise definite answer and a cure that would cause all of us an orgasmic scream of joy !!

Kind regards,

[lauracostis]

demografx

is the levitra your taking just for erectile dysfunction or is it for pois, what dosage do you take? how and when do you take it.  i know that levitra dialates blood vessels and stimulates conversion of cyclic gmp.  it works on many other areas of the body, dialting consricted vessels in the lungs. 

[Z_one]

Check out this : Bodybuilding.com Forums > More General Categories > Misc. > Why do people try to stop fapping?

Look up for the great posts by Devil_Z , I am sure the key to the solution is there,,,,

Z.

[GoingCrazy]

Check out this : Bodybuilding.com Forums > More General Categories > Misc. > Why do people try to stop fapping?

Look up for the great posts by Devil_Z , I am sure the key to the solution is there,,,,

Z.

Can't find it, they may have taken it off or something, can you give us a link?

[demografx]

demografx

is the levitra your taking just for erectile dysfunction or is it for pois, what dosage do you take? how and when do you take it.  i know that levitra dialates blood vessels and stimulates conversion of cyclic gmp.  it works on many other areas of the body, dialting consricted vessels in the lungs. 

Laurac, at one time I thought Levitra was "the cure" for POIS (for me). But I was taking testosterone injections at the time, so I might have misattributed what was working. Then the Levitra started to "fade" as a cure, but my testosterone use was also dwindling and then eventually discontinued.

Back then, and now, the primary reason for taking it was for ED.

Now, daily testosterone patches 15mg, appear to cure my POIS 75% to 90% per episode. Eight months since I've been on this treatment.

One theory I have is that - even if we're not low on testosterone, a boost might work nevertheless, for some people. I have just increased my dose 50%, with doc's approval. I just wrote to my endo to get his opinion on my theory.

[demografx]

itsmebutwho? and Z_one, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:

Our new POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/poiswebsite/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

If you want a copy (PDF), send me a Private Message with your regular email address and I'll send you back the PDF.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show the medical world - which often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community. This can help fight the immediate reaction of some: IT'S NOT "ALL IN OUR HEADS"!

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum for over 2 years, which has attracted over 150 POIS sufferers worldwide who have posted here, plus more than 350,000 page visits. Not bad for a rare malady!

[demografx]

itsmebutwho? and Z_one, this post might help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: over 2 years' worth of posts from 150+ Forum members, and an additional 150 POIS sufferers found on the Internet, but not on this forum.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://www.thenakedscientists.com/

for example, I tried
demografx POIS site:http://www.thenakedscientists.com/

and 1,000+ results came up for "demografx" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.