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  4. Post Orgasmic Illness Syndrome (POIS)
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Post Orgasmic Illness Syndrome (POIS)

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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11760 on: 23/02/2011 18:14:10 »
The test was almost 3 hours after ejaculation.
It was a spoon of semen. I delivered it all. They said the dilution ratio. But I didn't remember that. I was too happy that the test was positive.
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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11761 on: 23/02/2011 18:21:30 »
Quote from: horizon on 23/02/2011 17:38:47
forum skinprick test count so far:
positive= 1, negative= 2

Van, did Dr.W do the test?
how long after ejaculation did you do the test?
we should also compare the symptoms of the positive and the negative.

habibbou and nightinghale what are your symmptoms you never posted those.
« Last Edit: 23/02/2011 18:28:03 by CCconfucius »
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11762 on: 23/02/2011 18:28:24 »

Vandemolen, many thanks for reporting!
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Offline afghan666

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11763 on: 23/02/2011 19:13:34 »
http://www.reuniting.info/science/articles/acute_dopamine_depletion_causes_psychological_distress [nofollow]

 Demo here is half of the evidence u asked for.
 I dont kno about tests but i surely can check what will high and low levels of neurotransmitter can cause.i can match my symptoms. . . . . .its based on common sense on how much they will match.
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Offline carlitto

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11764 on: 23/02/2011 20:07:53 »
Quote from: Vandemolen3 on 23/02/2011 18:14:10
The test was almost 3 hours after ejaculation.
It was a spoon of semen. I delivered it all. They said the dilution ratio. But I didn't remember that. I was too happy that the test was positive.

Van I have a question: did they inject the fluid with a syringe under your skin? how much fluid did they inject in your body? I am considering doing the skinprick test by myself following Dr. W's description in the paper
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Offline Nightingale

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11765 on: 23/02/2011 20:28:27 »
Quote from: CCconfucius on 23/02/2011 18:21:30
Quote from: horizon on 23/02/2011 17:38:47
forum skinprick test count so far:
positive= 1, negative= 2

Van, did Dr.W do the test?
how long after ejaculation did you do the test?
we should also compare the symptoms of the positive and the negative.

habibbou and nightinghale what are your symmptoms you never posted those.

My biggest symptom is mental fatigue, with some physical too.  I'd describe it as Attention Deficit Disorder (not ADHD, I'm not hyperactive in the least afterwards) I get cataplexy in the mornings after, which is temporary paralysis, mostly with my legs.  I feel some muscle soreness in my lower body too.  I usually feel more deperessed, probably +2 points on a scale of 10.  I "zone out" a lot and my eyelids get very droopy.  People commonly ask "are you ok" when they see me, because I look upset or "washed out".  The symptoms are most prevalent 15 min. after ejaculation to 2 days after.  Still feel some effects 3-4 days after.

Vandemelon, there are lots of details I'd like to know about your skin ***** test.  Mine was a negative, but they didn't do it like Dr. Waldinger did in his study.  Was it injected under your skin? Or did they just dip the tip of a small needle in your semen and poke you?  It would be SO great to know!!
« Last Edit: 23/02/2011 20:35:14 by Nightingale »
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11766 on: 23/02/2011 20:43:15 »
Carlitto, this injection can lead to a shock. It is better to do this test in a hospital. Other allergy injections also can lead to a shock. A friend had a pollen allergy and he had to wait an hour in the hospital because he might get into a shock.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11767 on: 23/02/2011 20:55:30 »
Quote from: Nightingale on 23/02/2011 20:28:27
My biggest symptom is mental fatigue, with some physical too.  I'd describe it as Attention Deficit Disorder (not ADHD, I'm not hyperactive in the least afterwards) I get cataplexy in the mornings after, which is temporary paralysis, mostly with my legs.  I feel some muscle soreness in my lower body too.  I usually feel more deperessed, probably +2 points on a scale of 10.  I "zone out" a lot and my eyelids get very droopy.  People commonly ask "are you ok" when they see me, because I look upset or "washed out".  The symptoms are most prevalent 15 min. after ejaculation to 2 days after.  Still feel some effects 3-4 days after.

Vandemelon, there are lots of details I'd like to know about your skin ***** test.  Mine was a negative, but they didn't do it like Dr. Waldinger did in his study.  Was it injected under your skin? Or did they just dip the tip of a small needle in your semen and poke you?  It would be SO great to know!!
They did the test as described in the latest paper of dr. Waldinger. I don't have a medical background so I don't like to tell you or your doctors how to do this. Also because, as I told earlier, that injections can lead to a shock. When I read that Carlitto wants to do this himself this frightens me. I don't want that responsibility. I know that you and others have a lot of questions but I am not the one who can answer this.

The needle was prepared in another room, so I don't know the details. In fact I was in POIS, so not so focussed. It was injected in my skin. Not so deep. It's like other allergy skin pr.ick tests. It was diluted, that's for sure. But you can read this also in the latest paper of dr. Waldinger.
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Offline horizon

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11768 on: 23/02/2011 21:46:48 »
van,
you getting the hypo-desensization injections for free?
if not how much are they?
« Last Edit: 23/02/2011 22:03:30 by horizon »
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Offline horizon

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11769 on: 23/02/2011 21:54:32 »
carlitto, im sure you'll find a professional.
very little point doing it yourself id imagine.
i mentioned a german doctor below, give him a try.

Quote from: horizon on 31/01/2011 12:26:09
Weidinger S, Ring J, Köhn FM.
Department of Dermatology and Allergy, Technical University Munich, Munich, Germany. weidinger@lrz.tum.de
http://www.ncbi.nlm.nih.gov/pubmed/16129942

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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11770 on: 23/02/2011 21:56:24 »
Quote from: afghan666 on 23/02/2011 15:08:07
Hello evryone,
   A thought came to my mind.we have guys in forum who react badly to alcohol.my face goes pale if i smoke cigarettes.we might be having a sensitive or weak LIVER.the liver is responsible for producing antibodies,amino acids,hormones,blood,affects balancing sodium and neurotransmitters.it controls cholestrol,etc.
  there must be a relation between pois,allergy,neurotransmitter imbalance and liver.

I personally can tolerate alcohol fine. I can drink about 10 beers in one night, get drunk, and wake up with barely a hangover the next day, however I am only 22. For me ejaculation causes every part of my body to weaken and perhaps atrophy. This is why I believe the cause of POIS is the extra energy the body has to use in order to regenerate lost semen. But as far as alcohol goes if I drink moderately I've noticed my pain is lessened and my health improves.
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Taking ginger tea, fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.
 

Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11771 on: 23/02/2011 22:02:41 »
Quote from: Vandemolen3 on 23/02/2011 20:55:30
Quote from: Nightingale on 23/02/2011 20:28:27
My biggest symptom is mental fatigue, with some physical too.  I'd describe it as Attention Deficit Disorder (not ADHD, I'm not hyperactive in the least afterwards) I get cataplexy in the mornings after, which is temporary paralysis, mostly with my legs.  I feel some muscle soreness in my lower body too.  I usually feel more deperessed, probably +2 points on a scale of 10.  I "zone out" a lot and my eyelids get very droopy.  People commonly ask "are you ok" when they see me, because I look upset or "washed out".  The symptoms are most prevalent 15 min. after ejaculation to 2 days after.  Still feel some effects 3-4 days after.

Vandemelon, there are lots of details I'd like to know about your skin ***** test.  Mine was a negative, but they didn't do it like Dr. Waldinger did in his study.  Was it injected under your skin? Or did they just dip the tip of a small needle in your semen and poke you?  It would be SO great to know!!
They did the test as described in the latest paper of dr. Waldinger. I don't have a medical background so I don't like to tell you or your doctors how to do this. Also because, as I told earlier, that injections can lead to a shock. When I read that Carlitto wants to do this himself this frightens me. I don't want that responsibility. I know that you and others have a lot of questions but I am not the one who can answer this.

The needle was prepared in another room, so I don't know the details. In fact I was in POIS, so not so focussed. It was injected in my skin. Not so deep. It's like other allergy skin pr.ick tests. It was diluted, that's for sure. But you can read this also in the latest paper of dr. Waldinger.

One of the problems is acheiving the dilutions. As I understand it, in most cases you have to go to a special university lab for this. But to give an idea of proportions, to acheive a 1:40000 dilution, you'd have to put 1 cubic mm of semen into 1/6 cup distilled water (sterile cup). Then find the smallest syringe possible and use 50 cu mm ( a cube a little more than 1/8 in. per side) from the 1/6 cup.

1 mm of semen is inpracticle I'd say because it's not very homogeneous. So if you put only 1 mm it may be possible that there is less semen in that sample. So perhaps it would be better to put like 50 cu mm ( a drop +/-) of well mixed semen into 8-1/3 cups.

Of course you'd have to maintain sterility. If the drop is a little big or a little small, you'd have to add or subtract a portion of water to the 8.3 cups. So perhaps 1 cc of semen in 166 cups would be a little more consistent!

And of course there's the risk of shock....

Those are just ballpark numbers for perspective, so I don't suggest following them to the letter. As the disclaimer on the JackAss show says.... don't try this at home.  [:P]
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How does Murphey do it??
 

Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11772 on: 23/02/2011 22:04:49 »
Horizon, in The Netherlands there is a good public health system. I have to pay 130 euro a month for this insurrance so it is not for free. :)
But I don't have to pay for the desensization.
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Offline afghan666

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11773 on: 23/02/2011 22:11:53 »
Quote from: CCconfucius on 23/02/2011 17:13:54
Quote from: afghan666 on 23/02/2011 15:08:07
Hello evryone,
   A thought came to my mind.we have guys in forum who react badly to alcohol.my face goes pale if i smoke cigarettes.we might be having a sensitive or weak LIVER.the liver is responsible for producing antibodies,amino acids,hormones,blood,affects balancing sodium and neurotransmitters.it controls cholestrol,etc.
  there must be a relation between pois,allergy,neurotransmitter imbalance and liver.
 Fenugreek has liver protective properties.
 Turmeric is a gud liver protectant.i ll be checking out herbs used for hormone balancing and herbs good for live
 By the way fenugreek+ginseng+sulbutiamine+gingko biloba+optimen tabs hav an enormous improvement in pois and i am O ing daily.the only thing am concerned is whether fenugreek's effect will last or if i might build up some sort of tolerance.???
if you are in the US and you figure out what test you need to check out your liver you can go through this website to do you your test without doctors apointment, they use labcorp..http://www.prepaidlab.com/ [nofollow] i have been using them for almost 2 years and using them as i try to increase my vitamin d.


there is way to check out your neurotransmitter but will be very difficult to find a place to do it since it is very new.


Thanks for the guidance......
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11774 on: 23/02/2011 23:10:06 »
Today I had an O. in the late morning. Maybe I will get less symptoms because I have the chance to drink a lot of water during the day. It could be that my throat, theeth, gums and tongue gets more infected because of the dry mouth. When you have an O. at night you go to sleep. And during the night you don't drink. When you wake up the mouth is very dry. I think this causes more infections.

I will let you know tommorow if I have less symptoms. But today I also started with antibiotics for ten days because of a possible UTI. So if I have less symptoms this time I can't exactly say what did it. Maybe others can try this too. But it's important to drink a lot of water.
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11775 on: 23/02/2011 23:35:17 »
Quote from: afghan666 on 23/02/2011 19:13:34

http://www.reuniting.info/science/articles/acute_dopamine_depletion_causes_psychological_distress

 Demo here is half of the evidence u asked for.
 I dont kno about tests but i surely can check what will high and low levels of neurotransmitter can cause.i can match my symptoms. . . . . .its based on common sense on how much they will match.


Thanks, afghan!
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11776 on: 23/02/2011 23:48:20 »
Quote from: carlitto on 23/02/2011 20:07:53

Van I have a question: did they inject the fluid with a syringe under your skin? how much fluid did they inject in your body? I am considering doing the skinprick test by myself following Dr. W's description in the paper

Quote from: Vandemolen3 on 23/02/2011 20:43:15

Carlitto, this injection can lead to a shock. It is better to do this test in a hospital. Other allergy injections also can lead to a shock. A friend had a pollen allergy and he had to wait an hour in the hospital because he might get into a shock.


Thank you, Vandemolen!
« Last Edit: 24/02/2011 04:20:07 by demografx »
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Offline Habibou

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11777 on: 24/02/2011 01:26:40 »
Quote from: CCconfucius on 23/02/2011 18:21:30
Quote from: horizon on 23/02/2011 17:38:47
forum skinprick test count so far:
positive= 1, negative= 2

Van, did Dr.W do the test?
how long after ejaculation did you do the test?
we should also compare the symptoms of the positive and the negative.

habibbou and nightinghale what are your symmptoms you never posted those.

Here are my symptoms : -flue like symptoms
-headache (very intense)
-dizzy period
-blurry eyes
-ears blowing
-unbalanced of blood pressure
-heartbeat rate very high (even without sport)
-digestive matters (colon...)
-unbalanced of temperature in the body
-collapse after standing
-temperature of feet changing
-exhaustion
-troubles to remember,
-writing
-speaking
-white face
-muscles pain
-vomiting in the morning (less and less)
-"electricity" in the brain
-between legs pain
-stress feeling (narrow throat, spasm, sweting, need to drink/dried throat, nightmars...)
-thinner than the normal /need to eat a lot (always hungry)
-irritation on the skin sometimes
-belly pain/disorders
-difficulty walking, having intercourse
-buring eyes (just twice)

I have it 20% after arousal, compare to 100% after an O... I have a brain fog for 2 days at least which is the worst = dizzy, impression of "over living"/unreality. I have to say that I never tried drug, smoke 1/10 of a cigaret and been once drunk in my life ...
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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11778 on: 24/02/2011 06:51:43 »
Quote from: afghan666 on 23/02/2011 15:08:07
Hello evryone,
   A thought came to my mind.we have guys in forum who react badly to alcohol.my face goes pale if i smoke cigarettes.we might be having a sensitive or weak LIVER.the liver is responsible for producing antibodies,amino acids,hormones,blood,affects balancing sodium and neurotransmitters.it controls cholestrol,etc.
  there must be a relation between pois,allergy,neurotransmitter imbalance and liver.
 Fenugreek has liver protective properties.
 Turmeric is a gud liver protectant.i ll be checking out herbs used for hormone balancing and herbs good for live
 By the way fenugreek+ginseng+sulbutiamine+gingko biloba+optimen tabs hav an enormous improvement in pois and i am O ing daily.the only thing am concerned is whether fenugreek's effect will last or if i might build up some sort of tolerance.???

Hi afghan666,

Good to hear that fenugreek (amongst other things) is helping you with your POIS. I have been taking it daily myself for a long time now, and it is the best way I have found so far to minimise my POIS symptoms. I don't think I have built up a tolerance to it, but everybody's body is different. Interesting to hear that it helps to protect the liver.
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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11779 on: 24/02/2011 07:29:39 »
Quote from: afghan666 on 23/02/2011 17:08:58
Quote from: demografx on 23/02/2011 15:55:38
We don't "know" there's a neurotransmitter deficiency. Testing is highly inaccurate. Some evidence, please.

 It has been tested by scientists that low levels pf dopamine causes depression,loss of focus,Adhd and parkinson disease.After an O ,our body is depleted of dopamine which also results in high prolactin levels.prolactin is a sex and dopamine inhibiting hormone....after an O the body signals the release of prolactin as the natural process of mating is job done.But in pois sufferer the prolactin is released in far greater amounts thus it affects our focus,causes depression,ADHD,etc.the abnormal release might be an organ insuffiency e.g kidney,liver,thyroid or adrenal gland.

 For more evidence please google out ''effects of low levels of dopamine''...i m using android handy...other wise i wud had sent the links....


Am trying to put a piece in the puzzle...it might be one secondary or may be tertiary effects in the pois complex....

 Daveman is right...i agree...

I was convinced for a long time that low levels of dopamine were responsible for my POIS - during the last few years I have used Selegiline, L-Tyrosine, and Bupropion extensively (not all at the same time  [:)]), and I have also tried cabergoline.

None of these drugs felt like they were fighting my POIS symptoms, and did little to alleviate them. I'm not saying that dopamine does not play a key part in POIS - the whole prolactin/dopamine reaction seems like an excellent way to rationalise why POIS happens, but I personally have had no luck exploring this avenue.
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